Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation

Nature Communications

Volumn 4, Issue , 2013, Pages

  Hitosugi, Taro ^a   Zhou, Lu ^b   Fan, Jun ^a   Elf, Shannon ^a   Zhang, Liang ^b   Xie, Jianxin ^c   Wang, Yi ^c   Gu, Ting Lei ^c   Alečković, Masa ^d   Leroy, Gary ^d   Kang, Yibin ^d   Kang, Hee Bum ^a   Seo, Jae Ho ^a   Shan, Changliang ^a   Jin, Peng ^a   Gong, Weimin ^e   Lonial, Sagar ^a   Arellano, Martha L ^a   Khoury, Hanna J ^a   Chen, Georgia Z ^a   Shin, Dong M ^a   Khuri, Fadlo R ^a   Boggon, Titus J ^f   Kang, Sumin ^b   He, Chuan ^b   Chen, Jing ^a   more..

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c CELL SIGNALING TECHNOLOGY   (United States)

^d PRINCETON UNIVERSITY   (United States)

^e INSTITUTE OF BIOPHYSICS   (China)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOLYTIC ENZYME PHOSPHOGLYCERATE MUTASE 1; PHOSPHOGLYCERATE MUTASE; UNCLASSIFIED DRUG; 2,3 DIPHOSPHOGLYCERIC ACID; 2-PHOSPHOGLYCERATE; 3-PHOSPHOGLYCERATE; GLYCERIC ACID; HISTIDINE; PHOSPHOTYROSINE;

CANCER; CRYSTAL STRUCTURE; ENZYME ACTIVITY; GENE EXPRESSION; INHIBITOR; METABOLISM; PUBLIC HEALTH; TUMOR;

ARTICLE; CELL PROLIFERATION; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GLYCOLYSIS; METABOLIC PARAMETERS; NEOPLASM; SIGNAL TRANSDUCTION; UPREGULATION; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME STABILITY; ENZYMOLOGY; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

2,3-DIPHOSPHOGLYCERATE; AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME STABILITY; GLYCERIC ACIDS; GLYCOLYSIS; HISTIDINE; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEOPLASMS; PHOSPHOGLYCERATE MUTASE; PHOSPHORYLATION; PHOSPHOTYROSINE;

EID: 84877781067     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms2759     Document Type: Article

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