The antitumor activity of hydrophobin SC3, a fungal protein

Applied Microbiology and Biotechnology

Volumn 97, Issue 10, 2013, Pages 4385-4392

  Akanbi, Marijke Haas Jimoh ^a,b   Post, Eduard ^a   Van Putten, Sander M ^a   De Vries, Louwe ^a   Smisterova, Jarmila ^a   Meter Arkema, Anita H ^a   Wösten, Han A B ^c   Rink, Rick ^a   Scholtmeijer, Karin ^a,c  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY OF ILORIN   (Nigeria)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Cytokines; Fungus; Hydrophobin; Immunomodulation; SC3; Tumor suppression

Indexed keywords

CYTOKINES; HYDROPHOBINS; IMMUNO MODULATIONS; SC3; TUMOR SUPPRESSION;

ANIMALS; CELL CULTURE; CHEMOTHERAPY; CYTOTOXICITY; DERMATOLOGY; DRUG PRODUCTS; FUNGI; ONCOLOGY; PROTEINS;

TUMORS;

ANTINEOPLASTIC AGENT; HYDROPHOBIN SC3; INTERLEUKIN 10; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

CANCER; CHEMOTHERAPY; DISEASE CONTROL; IMMUNE RESPONSE; MUSHROOM; PROTEIN; RADIANCE; RODENT; TRADITIONAL MEDICINE; TUMOR;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL CULTURE; CELLULAR IMMUNITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; IMMUNOMODULATION; IN VITRO STUDY; INCUBATION TIME; MALE; MELANOMA CELL; MICROSCOPY; MITOSIS RATE; MOUSE; NONHUMAN; ORGAN WEIGHT; SARCOMA CELL; SCHIZOPHYLLUM COMMUNE; SPLEEN CELL; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; FUNGAL PROTEINS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; SCHIZOPHYLLUM;

ANIMALIA; BASIDIOMYCOTA; FUNGI; SCHIZOPHYLLUM COMMUNE;

EID: 84877779885     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-012-4311-x     Document Type: Article

References (32)

1. Chang R (2002) Bioactive polysaccharides from traditional Chinese medicine herbs as anticancer adjuvants. J Altern Complement Med 8:559-565 (Pubitemid 35291590)
2. Chen H-S, Tsai Y-F, Lin S, Lin C-C, Khoo K-H, Lin C-H, Wong C-H (2004) Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) polysaccharides. Bioorgan Med Chem 12:5595-5601 (Pubitemid 39304059)
3. De Visser KE, Eichten A, Coussens LM (2006) Paradoxical roles of the immune system during cancer development. Nature Rev Cancer 6:24-37 (Pubitemid 43053650)
4. De Vocht ML, Scholtmeijer K, van der Vegte EW, de Vries OMH, Sonveaux N, Wösten HAB, Ruysschaert JM, Hadziioannou G, Wessels JGH, Robillard GT (1998) Structural characterization of the hydrophobin SC3, as a monomer and after self-assembly at hydrophobic/hydrophilic interfaces. Biophys J 74:1-10
5. Fairbairn NJ (1953) A modified anthrone reagent. Chemistry and Industry 4:86
6. Hirazumi A, Furusawa E (1999) An immunomodulatory polysaccharide-rich substance from the fruit juice of Morinda citrifolia (Noni) with antitumor activity. Phytother Res 13:380-387 (Pubitemid 29401386)
7. Janssen MI, van Leeuwen MBM, Scholtmeijer K, van Kooten TG, Dijkhuizen L, Wösten HAB (2002) Coating with genetic engineered hydrophobin promotes growth of fibroblasts on a hydrophobic solid. Biomaterials 23:4847-4854 (Pubitemid 35286707)
8. Janssen MI, van Leeuwen MBM, van Kooten TG, de Vries J, Dijkhuizen L, Wösten HAB (2004) Promotion of fibroblast activity by coating with hydrophobins in the β-sheet end state. Biomaterials 25:2731-2739 (Pubitemid 38201299)
9. Jin M, Jung HJ, Choi JJ, Jeon H, Oh JH, Kim B, Shin SS, Lee JK, Yoon K, Kim S (2003) Activation of selective transcription factors and cytokines by water-soluble extract from Lentinus lepideus. Exp Biol M 228:749-758 (Pubitemid 37163267)
10. Kershaw MJ, Talbot NJ (1998) Hydrophobins and repellents: proteins with fundamental roles in fungal morphogenesis. Fungal Genet Biol 23:18-33 (Pubitemid 28403135)
11. Linder MB, Szilvay GR, Nakari-Setälä T, Penttilä ME (2005) Hydrophobins: the protein-amphiphiles of filamentous fungi. FEMS Microbiol Rev 29:877-896 (Pubitemid 41416842)
12. Liu F, Ooi VE, Liu WK, Chang ST (1996) Immunomodulation and antitumor activity of polysaccharide-protein complex from the culture filtrates of a local edible mushroom, Tricholoma lobayense. Gen Pharmacol 27:621-624 (Pubitemid 26233330)
13. Lowry OH, Rosbrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
14. Lugones LG, de Jong JF, de Vries OMH, Jalving R, Dijksterhuis J, Wösten HAB (2004) The SC15 protein of Schizophyllum commune mediates formation of aerial hyphae and attachment in the absence of the SC3 hydrophobin. Mol Microbiol 53:707-716 (Pubitemid 38998187)
15. Lull C, Wichers HJ, Savelkoul HFJ (2005) Antiinflammatory and immunomodulating properties of fungal metabolites. Mediators Inflamm 9:3-80
16. Martin GG, Cannon GC, McCormick CL (2000) Sc3p hydrophobin organization in aqueous media and assembly onto surfaces as mediated by the associated polysaccharide schizophyllan. Biomacromolecules 1:49-60
17. Omarsdottir S, Freysdottir J, Olafsdottir ES (2007) Immunomodulating polysaccharides from the lichen Thamnolia vermicularis var. subuliformis. Phytomedicine 14:179-184 (Pubitemid 46138160)
18. Scholtmeijer K, Janssen MI, Gerssen B, de Vocht ML, van Leeuwen MBM, van Kooten TG, Wösten HAB, Wessels JGH (2002) Surface modifications created by using engineered hydrophobins. Appl Environ Microbiol 68:1367-1373 (Pubitemid 34205378)
19. Scholtmeijer K, de Vocht ML, Rink R, Robillard GT, Wösten HAB (2009) Assembly of the fungal SC3 hydrophobin into functional amyloid fibrils depends on its concentration and is promoted by cell wall polysaccharides. J Biol Chem 284:26309-26314
20. Scudiero DA, Shoemaker RH, Paull KD, Monks A, Tierney S, Nofziger TH, Currens MJ, Seniff D, Boyd MR (1988) Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cancer Res 48:4827-4833
21. Thunnissen FBJM, Ambergen AW, Koss M, Travis WD, O'Leary TJ, Ellis IO (2001) Mitotic counting in surgical pathology: sampling bias, heterogeneity and statistical uncertainty. Histopathology 39:1-8 (Pubitemid 32848268)
22. Van der Vegt W, van der Mei HC, Wösten HAB, Wessels JGH, Busscher HJ (1996) A comparison of the surface activity of the fungal hydrophobin SC3p with those of other proteins. Biophys Chem 57:253-260
23. Van Wetter MA, Wösten HAB, Sietsma JH, Wessels JGH (2000) Hydrophobin gene expression affects hyphal wall composition in Schizophyllum commune. Fungal Genet Biol 31:99-104 (Pubitemid 32182238)
24. Wasser SP (2002) Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl Microbiol Biotechnol 60:258-274
25. Wasser SP (2011) Current findings, future trends, and unsolved problems in studies of medicinal mushrooms. Appl Microbiol Biotechnol 89:1323-1332
26. Wessels JGH (1994) Developmental regulation of fungal cell wall formation. Annu Rev Phytopathol 32:413-437 (Pubitemid 2151443)
27. Wessels JGH (1997) Hydrophobins, proteins that change the nature of the fungal surface. Adv Microbial Physiol 38:1-45 (Pubitemid 26377552)
28. Willment JA, Brown GD (2008) C-type lectin receptors in antifungal immunity. Trends Microbiol 16:27-32
29. Wösten HAB (2001) Hydrophobins: multipurpose proteins. Annu Rev Microbiol 55:625-646 (Pubitemid 32978118)
30. Wösten HAB, de Vocht ML (2000) Hydrophobins, the fungal coat unravelled. Biochim Biophys Acta 1469:79-86
31. Wösten HAB, van Wetter MA, Lugones LG, van der Mei HC, Busscher HJ, Wessels JGH (1999) How a fungus escapes the water to grow into the air. Curr Biol 9:85-88 (Pubitemid 29083532)
32. Zampieri F, Wösten HAB, Scholtmeijer K (2010) Creating surface properties using a palette of hydrophobins. Materials 3:4607-4625