Immunomodulating polysaccharides from the lichen Thamnolia vermicularis var. subuliformis

Phytomedicine

Volumn 14, Issue 2-3, 2007, Pages 179-184

  Omarsdottir, Sesselja ^a   Freysdottir, Jona ^b   Olafsdottir, Elin Soffia ^a  

^a UNIVERSITY OF ICELAND   (Iceland)

^b LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

Author keywords

immunmodulating polysaccharides; lichen; Thamnolia vermicularis var. subuliformis

Indexed keywords

BETA GLUCAN; GLYCAN DERIVATIVE; INTERLEUKIN 10; MANNAN; POLYSACCHARIDE; THAMNOLAN; THS 2; THS 4; THS 5; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CELL STIMULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG ACTIVITY; DRUG STRUCTURE; IMMUNOMODULATION; IN VITRO STUDY; LICHEN; MITOGENESIS; MOLECULAR WEIGHT; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RAT; SPLEEN; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; THAMNOLIA VERMICULARIS SUBULIFORMIS;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNE SYSTEM; IMMUNOLOGIC FACTORS; INTERLEUKIN-10; LICHENS; MACROPHAGES, PERITONEAL; PHYTOTHERAPY; PLANT EXTRACTS; POLYSACCHARIDES; RATS; SPLEEN; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS; THAMNOLIA; THAMNOLIA VERMICULARIS;

EID: 33846404098     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2006.11.012     Document Type: Article

References (27)

1. Asahina Y., and Shibata S. Chemistry of Lichen Substances (1973), A. Asher & Co. Ltd., Vaals-Amsterdam
2. Bao X., Liu C., Fang J., and Li X. Structural and immunological studies of a major polysaccharide from spores of Ganoderma lucidium (FR.) Karst. Carbohydr. Res. 332 (2001) 67-74
3. Barreto-Bergter E., and Gorin P.A.J. Structural chemistry of polysaccharides from fungi and lichens. Adv. Carbohydr. Chem. Biochem. 67 (1983) 103
4. Bradford M. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248
5. Falch B.H., Espevik T., Ryan L., and Stokke B.T. The cytokine stimulating activity of (1(3)-β-d-glucans is dependent on the triple helix conformation. Carbohydr. Res. 329 (2000) 587-596
6. Hale M.E. The Biology of Lichens. second ed (1974), Edward Arnold Ltd., London
7. Han S.B., Park S.H., Lee K.H., Lee C.W., Lee S.H., Kim H.C., Kim Y.S., Lee H.S., and Kim H.M. Polysaccharides isolated from the radix of Platycodon grandiflorum selectively activates B cells and macrophages but not T cells. Int. Immunopharmacol. 1 (2001) 1969-1978
8. Hansen H.P., and Schädler M. Pflanzen in der traditionellen chinesischen Medizin. Dtsch. Apoth. Ztg. 125 (1985) 1239-1243
9. Im S.A., Oh S.T., Song S., Kim M.R., Kim D.S., Woo S.S., Jo T.H., Park Y.I., and Lee C.K. Identification of optimal molecular size of modified aloe polysaccharides with maximum immunomodulatory activity. Int. Immunopharmacol. 5 (2005) 271-279
10. Ingólfsdóttir K., Jurcic K., Fischer B., and Wagner H. Immunologically active polysaccharide from Cetraria islandica. Planta Med. 60 (1994) 527-531
11. Ingólfsdóttir K., Wiedemann B., Birgisdóttir M., Nenninger A., Jónsdóttir S., and Wagner H. Inhibitory effects of baeomycesic acid from the lichen Thamnolia subuliformis on 5-lipoxygenase in vitro. Phytomedicine 4 (1997) 125-128
12. Jones C., Todeschini A.R., Agrellos A.O., Previato J.O., and Mendonca-Previato L. Heterogeneity in the biosynthesis of mucin O-glycans from Trypanosoma cruzi Tulahuen strain with the expression of novel galactofuranosyl-containing oligosaccharides. Biochemistry 43 (2004) 11889-11897
13. Levery S.B., Toledo M.S., Straus A.H., and Takahashi H.K. Structure elucidation of sphingolipids from the mycopathogen Paracoccidioides brasiliensis: an immunodominant β-galactofuranose residue is carried by a novel glycosylionsitol phosphorylceramide antigen. Biochemistry 37 (1988) 8764-8775
14. Mizuno T. The extraction and development of antitumor-active polysaccharides from medicinal mushrooms in Japan. Int. J. Med. Mushrooms 1 (1999) 9-29
15. Olafsdottir E.S., and Ingolfsdottir K. Polysaccharides from lichens: structural characteristics and biological activity. Planta Med. 67 (2001) 199-208
16. Olafsdottir E.S., Omarsdottir S., Paulsen B.S., Jurcic K., and Wagner H. Rhamnopyranosylgalactofuranan, a new immunologically active polysaccharide from Thamnolia subuliformis. Phytomedicine 6 (1999) 273-279
17. Olafsdottir E.S., Ingolfsdottir K., Barsett H., Paulsen B.S., Jurcic K., and Wagner H. Immunologically active (1→3)-(1→4)-α-D-glucan from Cetraria islandica. Phytomedicine 6 (1999) 33-39
18. Olafsdottir E.S., Omarsdottir S., Paulsen B.S., and Wagner H. Immunologically active O6-branched (1→3)-β-glucan from the lichen Thamnolia vermicularis var. subuliformis. Phytomedicine 10 (2003) 318-324
19. Omarsdottir S., Freysdottir J., Barsett H., Paulsen B.S., and Olafsdottir E.S. Effect of lichen heteroglycans on proliferation and IL-10 secretion by rat spleen cells and TNF-α secretion by rat peritoneal macrophages in vitro. Phytomedicine 12 (2005) 461-467
20. Omarsdottir S., Petersen B.O., Paulsen B.S., Togola A., Duus J.Ø., and Olafsdottir E.S. Structural characterisation of novel lichen heteroglycans by NMR-spectroscopy and methylation analysis. Carbohydr. Res. 341 (2006) 2449-2455
21. Paulsen B.S., Olafsdottir E.S., and Ingólfsdóttir K. Chromatography and electrophoresis in separation and characterization of polysaccharides from lichens. J. Chromatogr. A 967 (2002) 163-171
22. Purvis O.W., Coppins B.J., Hawksworth P.W., and Moore D.M. The Lichen Flora of Great Britain and Ireland (1992), The British Lichen Society, St. Edmundsbury Press, Great Britian
23. Sassaki G.L., Ferreira J.C., Glienke-Blanco C., Torri G., De Toni F., Gorin P.A.J., and Iacomini M. Pustulan and branched β-galactofuranan from the phytopathogenic fungus Guignardia citricarpa, excreted from media containing glucose and sucrose. Carbohydr. Polym. 48 (2002) 385-389
24. Suzuki E., Toledo M.S., Takahashi H.K., and Straus A.H. A monoclonal antibody directed to teminal residue of β-galactofuranose of a glycolipid from Paracoccidioides brasiliensis: cross-reactivity with Leishmania major and Trypanosoma cruzi. Glycobiology 7 (1997) 463-468
25. Theler A. Systematics, phylogeny and classification. In: Nash III T.H. (Ed). Lichen Biology (1996), Cambridge University Press, Cambridge 238-239
26. Wang L.S., Narui T., Harada H., Culberson C.F., and Culberson W.L. Ethnic uses of lichens in Yunnan, China. Bryologist 104 (2001) 345-349
27. Yamada H., and Kiyhara H. Complement-activating polysaccharides from medicinal herbs. In: Wagner H. (Ed). Immunomodulatory Agents from Plants (1999), Birkhäuser Verlag, Basel 161-202