Genetic analysis of reaction time variability: Room for improvement?

Psychological Medicine

Volumn 43, Issue 6, 2013, Pages 1323-1333

  Kuntsi, J ^a   Frazier Wood, A C ^b   Banaschewski, T ^c   Gill, M ^d   Miranda, A ^e   Oades, R D ^f   Roeyers, H ^g   Rothenberger, A ^h   Steinhausen, H C ^i,j,k   Van Der Meere, J J ^l   Faraone, S V ^m   Asherson, P ^a   Rijsdijk, F ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d ST JAMES S HOSPITAL   (Ireland)

^e UNIVERSITY OF VALENCIA   (Spain)

^f UNIVERSITY OF DUISBURG ESSEN   (Germany)

^g GHENT UNIVERSITY   (Belgium)

^h UNIVERSITY OF GÖTTINGEN   (Germany)

ⁱ UNIVERSITY OF ZURICH   (Switzerland)

^j UNIVERSITY OF BASEL   (Switzerland)

^k AARHUS UNIVERSITY HOSPITAL   (Denmark)

^l UNIVERSITY OF GRONINGEN   (Netherlands)

^m State University of New York Upstate Medical University: College of Medicine   (United States)

more..

Author keywords

ADHD; event rate; genetic effects; reaction time variability; rewards

Indexed keywords

ADOLESCENT; ATTENTION DEFICIT DISORDER; BIOLOGICAL MODEL; CASE CONTROL STUDY; CHILD; DIZYGOTIC TWINS; FEMALE; GENETICS; HUMAN; INHIBITION (PSYCHOLOGY); MALE; MONOZYGOTIC TWINS; PHENOTYPE; PHYSIOLOGY; PSYCHOLOGY; REACTION TIME; TWINS; ARTICLE; PSYCHOLOGICAL ASPECT;

ADOLESCENT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CASE-CONTROL STUDIES; CHILD; FEMALE; HUMANS; INHIBITION (PSYCHOLOGY); MALE; MODELS, GENETIC; PHENOTYPE; REACTION TIME; TWINS; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 84877777710     PISSN: 00332917     EISSN: 14698978     Source Type: Journal    
DOI: 10.1017/S0033291712002061     Document Type: Article

References (37)

1. Andreou P, Neale BM, Chen W, Christiansen H, Gabriels I, Heise A, Meidad S, Muller UC, Uebel H, Banaschewski T, Manor I, Oades R, Roeyers H, Rothenberger A, Sham P, Steinhausen HC, Asherson P, Kuntsi J (2007). Reaction time performance in ADHD: Improvement under fast-incentive condition and familial effects. Psychological Medicine 37, 1703-1715.
2. Asherson P, Zhou K, Anney RJ, Franke B, Buitelaar J, Ebstein R, Gill M, Altink M, Arnold R, Boer F, Brookes K, Buschgens C, Butler L, Cambell D, Chen W, Christiansen H, Feldman L, Fleischman K, Fliers E, Howe-Forbes R, Goldfarb A, Heise A, Gabriels I, Johansson L, Lubetzki I, Marco R, Medad S, Minderaa R, Mulas F, Muller U, Mulligan A, Neale B, Rijsdijk F, Rabin K, Rommelse N, Sethna V, Sorohan J, Uebel H, Psychogiou L, Weeks A, Barrett R, Xu X, Banaschewski T, Sonuga-Barke E, Eisenberg J, Manor I, Miranda A, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Steinhausen HC, Taylor E, Thompson M, Faraone SV (2008). A high-density SNP linkage scan with 142 combined subtype ADHD sib pairs identifies linkage regions on chromosomes 9 and 16. Molecular Psychiatry 13, 514-521.
3. Borger N, van der Meere J (2000). Motor control and state regulation in children with ADHD: A cardiac response study. Biological Psychology 51, 247-267.
4. Brotman MA, Rooney MH, Skup M, Pine DS, Leibenluft E (2009). Increased intrasubject variability in response time in youths with bipolar disorder and at-risk family members. Journal of the American Academy of Child and Adolescent Psychiatry 48, 628-635.
5. Castellanos FX, Kelly C, Milham MP (2009). The restless brain : Attention-deficit hyperactivity disorder, resting-state functional connectivity, and intrasubject variability. Canadian Journal of Psychiatry 54, 665-672.
6. Chen W, Zhou K, Sham P, Franke B, Kuntsi J, Campbell D, Fleischman K, Knight J, Andreou P, Arnold R, Altink M, Boer F, Boholst MJ, Buschgens C, Butler L, Christiansen H, Fliers E, Howe-Forbes R, Gabriels I, Heise A, Korn-Lubetzki I, Marco R, Medad S, Minderaa R, Muller UC, Mulligan A, Psychogiou L, Rommelse N, Sethna V, Uebel H, McGuffin P, Plomin R, Banaschewski T, Buitelaar J, Ebstein R, Eisenberg J, Gill M, Manor I, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Taylor E, Thompson M, Faraone SV, Asherson P (2008). DSM-IV combined type ADHD shows familial association with sibling trait scores : A sampling strategy for QTL linkage. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B, 1450-1460.
7. Conners CK (2003). Conners Rating Scales-Revised : Technical Manual. MHS.
8. Conners CK, Sitarenios G, Parker JD, Epstein JN (1998a). The revised Conners Parent Rating Scale (CPRS-R): Factor structure, reliability, and criterion validity. Journal of Abnormal Child Psychology 26, 257-268.
9. Conners CK, Sitarenios G, Parker JD, Epstein JN (1998b). Revision and restandardization of the Conners Teacher Rating Scale (CTRS-R): Factor structure, reliability, and criterion validity. Journal of Abnormal Child Psychology 26, 279-291.
10. Cronbach LJ, Furby L (1970). How we should measure change : Or should wePsychological Bulletin 74, 68-80.
11. Halperin JM, Trampush JW, Miller CJ, Marks DJ, Newcorn JH (2008). Neuropsychological outcome in adolescents/young adults with childhood ADHD: Profiles of persisters, remitters and controls. Journal of Child Psychology and Psychiatry 49, 958-966.
12. Johns G (1981). Difference score measures of organizational behavior variables : A critique. Organizational Behavior and Human Performance 27, 443-463.
13. Johnson KA, Kelly SP, Bellgrove MA, Barry E, Cox M, Gill M, Robertson IH (2007). Response variability in attention deficit hyperactivity disorder : Evidence for neuropsychological heterogeneity. Neuropsychologia 45, 630-638.
14. Kaiser S, Roth A, Rentrop M, Friederich HC, Bender S, Weisbrod M (2008). Intra-individual reaction time variability in schizophrenia, depression and borderline personality disorder. Brain and Cognition 66, 73-82.
15. Kuntsi J, Andreou P, Ma J, Borger NA, van der Meere JJ (2005). Testing assumptions for endophenotype studies in ADHD: Reliability and validity of tasks in a general population sample. BMC Psychiatry 5, 40.
16. Kuntsi J, Klein C (2012). Intraindividual variability in ADHD and its implications for research of causal links. Current Topics in Behavioral Neurosciences 9, 67-91.
17. Kuntsi J, Rogers H, Swinard G, Borger N, van der Meere J, Rijsdijk F, Asherson P (2006). Reaction time, inhibition, working memory and delay aversion performance: Genetic influences and their interpretation. Psychological Medicine 36, 1613-1624.
18. Kuntsi J, Wood AC, Rijsdijk F, Johnson KA, Andreou P, Albrecht B, Arias-Vasquez A, Buitelaar JK, McLoughlin G, Rommelse NN, Sergeant JA, Sonuga-Barke EJ, Uebel H, van der Meere JJ, Banaschewski T, Gill M, Manor I, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Steinhausen HC, Faraone SV, Asherson P (2010). Separation of cognitive impairments in attention-deficit/hyperactivity disorder into 2 familial factors. Archives of General Psychiatry 67, 1159-1167.
19. Kuntsi J, Wood AC, van Der Meere J, Asherson P (2009). Why cognitive performance in ADHD may not reveal true potential : Findings from a large population-based sample. Journal of the International Neuropsychological Society 15, 570-579.
20. Loehlin JC (1996). The Cholesky approach: A cautionary note. Behavior Genetics 26, 65-69.
21. Neale MC, Boker SM, Xie G, Maes H (2006). Mx: Statistical Modeling. Department of Psychiatry : Richmond, VA.
22. Nikolas MA, Burt SA (2010). Genetic and environmental influences on ADHD symptom dimensions of inattention and hyperactivity : A meta-analysis. Journal of Abnormal Psychology 119, 1-17.
23. OConnell RG, Dockree PM, Bellgrove MA, Turin A, Ward S, Foxe JJ, Robertson IH (2009). Two types of action error : Electrophysiological evidence for separable inhibitory and sustained attention neural mechanisms producing error on go/no-go tasks. Journal of Cognitive Neuroscience 21, 93-104.
24. Oliver BR, Plomin R (2007). Twins Early Development Study (TEDS): A multivariate, longitudinal genetic investigation of language, cognition and behavior problems from childhood through adolescence. Twin Research and Human Genetics 10, 96-105.
25. Peter JP, Churchill GA, Brown TJ (1993). Caution in the use of difference scores in consumer research. Journal of Consumer Research 19, 655-662.
26. Rijsdijk FV, van Haren NE, Picchioni MM, McDonald C, Toulopoulou T, Hulshoff Pol HE, Kahn RS, Murray R, Sham PC (2005). Brain MRI abnormalities in schizophrenia : Same genes or same environmentPsychological Medicine 35, 1399-1409.
27. Rommelse NN, Altink ME, Oosterlaan J, Buschgens CJ, Buitelaar J, Sergeant JA (2008). Support for an independent familial segregation of executive and intelligence endophenotypes in ADHD families. Psychological Medicine 38, 1595-1606.
28. Sergeant JA (2005). Modeling attention-deficit/hyperactivity disorder : A critical appraisal of the cognitive-energetic model. Biological Psychiatry 57, 1248-1255.
29. Slusarek M, Velling S, Bunk D, Eggers C (2001). Motivational effects on inhibitory control in children with ADHD. Journal of the American Academy of Child and Adolescent Psychiatry 40, 355-363.
30. Taylor E, Everitt B, Thorley G, Schachar R, Rutter M, Wieselberg M (1986a). Conduct disorder and hyperactivity : II. A cluster analytic approach to the identification of a behavioural syndrome. British Journal of Psychiatry 149, 768-777.
31. Taylor E, Schachar R, Thorley G, Wieselberg M (1986b). Conduct disorder and hyperactivity : I. Separation of hyperactivity and antisocial conduct in British child psychiatric patients. British Journal of Psychiatry 149, 760-767.
32. Trouton A, Spinath FM, Plomin R (2002). Twins early development study (TEDS): A multivariate, longitudinal genetic investigation of language, cognition and behavior problems in childhood. Twin Research 5, 444-448.
33. Uebel H, Albrecht B, Asherson P, Borger NA, Butler L, Chen W, Christiansen H, Heise A, Kuntsi J, Schafer U, Andreou P, Manor I, Marco R, Miranda A, Mulligan A, Oades RD, van der Meere J, Faraone SV, Rothenberger A, Banaschewski T (2010). Performance variability, impulsivity errors and the impact of incentives as genderindependent endophenotypes for ADHD. Journal of Child Psychology and Psychiatry 51, 210-218.
34. van der Meere JJ (2002). The role of attention. In Hyperactivity Disorders of Childhood (ed. S. Sandberg), pp. 162-213.
35. Cambridge University Press : Cambridge. Wood AC, Asherson P, van der Meere JJ, Kuntsi J (2010). Separation of genetic influences on attention deficit hyperactivity disorder symptoms and reaction time performance from those on IQ. Psychological Medicine 40, 1027-1037.
36. Wood AC, Rijsdijk F, Johnson KA, Andreou P, Albrecht B, Arias-Vasquez A, Buitelaar JK, McLoughlin G, Rommelse NN, Sergeant JA, Sonuga-Barke EJ, Uebel H, van der Meere JJ, Banaschewski T, Gill M, Manor I, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Steinhausen HC, Faraone SV, Asherson P, Kuntsi J (2011). The relationship between ADHD and key cognitive phenotypes is not mediated by shared familial effects with IQ. Psychological Medicine 41, 861-871.
37. Yordanova J, Kolev V, Albrecht B, Uebel H, Banaschewski T, Rothenberger A (2011). May posterror performance be a critical factor for behavioral deficits in attention-deficit/hyperactivity disorder Biological Psychiatry 70, 246-254.