-
1
-
-
84861583388
-
New quinazolinone-pyrimidine hybrids:Synthesis, anti-inflammatory, and ulcerogenicity studies
-
Abbas E. S., Awadallah M. F., Ibrahim A. N. et al. New quinazolinone-pyrimidine hybrids:Synthesis, anti-inflammatory, and ulcerogenicity studies. Eur J Med Chem: 2012; 53 141 149
-
(2012)
Eur J Med Chem
, vol.53
, pp. 141-149
-
-
Abbas, E.S.1
Awadallah, M.F.2
Ibrahim, A.N.3
-
2
-
-
77954313516
-
Synthesis of some new 4(3H)-quinazolinone-2-carboxaldehyde thiosemicarbazones and their metal complexes and a study on their anticonvulsant, analgesic, cytotoxic and antimicrobial activities
-
Ali M. M., Mohamed A. Y., El-Bayouki M. A. et al. Synthesis of some new 4(3H)-quinazolinone-2-carboxaldehyde thiosemicarbazones and their metal complexes and a study on their anticonvulsant, analgesic, cytotoxic and antimicrobial activities. Eur J med Chem: 2010; 45 3365 3373
-
(2010)
Eur J Med Chem
, vol.45
, pp. 3365-3373
-
-
Ali, M.M.1
Mohamed, A.Y.2
El-Bayouki, M.A.3
-
3
-
-
0023805583
-
Histologic evidence of an abnormal bone remodeling in b-cell malignancies other than multiple myeloma
-
Marcelli C., Chappard D., Rossi J. F. et al. Histologic evidence of an abnormal bone remodeling in b-cell malignancies other than multiple myeloma. Cancer: 1988; 62 1163 1170
-
(1988)
Cancer
, vol.62
, pp. 1163-1170
-
-
Marcelli, C.1
Chappard, D.2
Rossi, J.F.3
-
4
-
-
48549096209
-
Inhibition of mammalian aspartate transcarbamylase by quinazolinone derivatives
-
Balbaa M., Abdel-Megeed M., Diab T. et al. Inhibition of mammalian aspartate transcarbamylase by quinazolinone derivatives. J. Enzyme Inhib Med Chem: 2008; 23 483 492
-
(2008)
J. Enzyme Inhib Med Chem
, vol.23
, pp. 483-492
-
-
Balbaa, M.1
Abdel-Megeed, M.2
Diab, T.3
-
5
-
-
0037109014
-
ZD1839 (Iressa): An orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy
-
Wakeling A. E., Guy S. P., Woodburn J. R. et al. An Orally Active Inhibitor of Epidermal Growth Factor Signaling with Potential for Cancer Therapy. Cancer Res: 2002; 62 5749 5754 (Pubitemid 35204731)
-
(2002)
Cancer Research
, vol.62
, Issue.20
, pp. 5749-5754
-
-
Wakeling, A.E.1
Guy, S.P.2
Woodburn, J.R.3
Ashton, S.E.4
Curry, B.J.5
Barker, A.J.6
Gibson, K.H.7
-
6
-
-
33750527318
-
Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4(3H)-quinazolinone analogs
-
DOI 10.1016/j.bmc.2006.08.030, PII S0968089606006894
-
Rashood S. T., Aboldahab I. A., Nagi M. N. et al. Synthesis, Dihydrofolate Reductase Inhibition, and Molecular Modeling Study of Some New 4(3H)-Quinazolinone Analogues. Bioorg Med Chem: 2006; 14 8608 8621 (Pubitemid 44667527)
-
(2006)
Bioorganic and Medicinal Chemistry
, vol.14
, Issue.24
, pp. 8608-8621
-
-
Al-Rashood, S.T.1
Aboldahab, I.A.2
Nagi, M.N.3
Abouzeid, L.A.4
Abdel-Aziz, A.A.M.5
Abdel-hamide, S.G.6
Youssef, K.M.7
Al-Obaid, A.M.8
El-Subbagh, H.I.9
-
7
-
-
33750491945
-
N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy] -5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor
-
DOI 10.1021/jm060434q
-
Hennequin L. F., Allen J., Breed J. et al. N-(5-chloro-1,3-benzodioxol-4- yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy) quinazoline 4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor. J Med Chem: 2006; 49 6465 6488 (Pubitemid 44657442)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.22
, pp. 6465-6488
-
-
Hennequin, L.F.1
Allen, J.2
Breed, J.3
Curwen, J.4
Fennell, M.5
Green, T.P.6
Lambert-Van Der Brempt, C.7
Morgentin, R.8
Norman, R.A.9
Olivier, A.10
Otterbein, L.11
Ple, P.A.12
Warin, N.13
Costello, G.14
-
8
-
-
1442359950
-
Efficient Synthesis of 4-Aminoquinazoline and Thieno[3,2-d]pyrimidin-4- ylamine Derivatives by Microwave Irradiation
-
Rocco S. A., Barbarini J. E., Rittner R. Efficient Synthesis of 4-Aminoquinazoline and Thieno[3,2-d]pyrimidin-4-ylamine Derivatives by Microwave Irradiation. Synthesis: 2004; 3 429 435
-
(2004)
Synthesis
, vol.3
, pp. 429-435
-
-
Rocco, S.A.1
Barbarini, J.E.2
Rittner, R.3
-
9
-
-
0025741216
-
Characterization of effective chemopreventive agents in mammary gland in vitro using an initiation-promotion protocol
-
Mehta R. G., Moon R. C. Characterization of effective chemopreventive agents in mammary gland in vitro using an initiation-promotion protocol. Anti-cancer Res: 1991; 11 593 596
-
(1991)
Anti-cancer Res
, vol.11
, pp. 593-596
-
-
Mehta, R.G.1
Moon, R.C.2
-
10
-
-
0034655238
-
Chemoprevention of Breast Cancer in Rats by Celecoxib, a Cyclooxygenase 2 Inhibitor1
-
Harris R. E., Alshafie G. A., Abou-Issa H. et al. Chemoprevention of Breast Cancer in Rats by Celecoxib, a Cyclooxygenase 2 Inhibitor1. Cancer Res: 2001; 60 2101 2103
-
(2001)
Cancer Res
, vol.60
, pp. 2101-2103
-
-
Harris, R.E.1
Alshafie, G.A.2
Abou-Issa, H.3
-
11
-
-
84899774763
-
Celecoxib inhibits vascular endothelial growth factor expression in and reduces angiogenesis and metastasis of human pancreatic cancer via suppression of sp1 transcription factor activity
-
Daoyan W., Liwei W., Yanjuan H. et al. Celecoxib inhibits vascular endothelial growth factor expression in and reduces angiogenesis and metastasis of human pancreatic cancer via suppression of sp1 transcription factor activity. Cancer Res: 2004; 64 1916 1930
-
(2004)
Cancer Res
, vol.64
, pp. 1916-1930
-
-
Daoyan, W.1
Liwei, W.2
Yanjuan, H.3
-
12
-
-
0038339582
-
-
Angew Chem Int Ed
-
Yoshimura F., Rivkin A., gabarda A. E. et al. Synthesis and Conformational Analysis of (E)-9,10-Dehydroepothilone B, the Most Potent Epothilone Reported to Date: A Suggestive Linkage Between Observations in the Chemistry and Biology of Epothilones. Angew Chem Int Ed. 2003; 42 2518 2521
-
(2003)
Synthesis and Conformational Analysis of (E)-9,10-Dehydroepothilone B, the Most Potent Epothilone Reported to Date: A Suggestive Linkage between Observations in the Chemistry and Biology of Epothilones
, vol.42
, pp. 2518-2521
-
-
Yoshimura, F.1
Rivkin, A.2
Gabarda, A.E.3
-
13
-
-
36949021034
-
Synthesis and structure-activity relationships of potent antitumor active quinoline and naphthyridine derivatives
-
DOI 10.2174/187152007784111313
-
Srivastava S. K., Jha A., Agarwal S. K. et al. Synthesis and structure-activity relationships of potent antitumor active quinoline and naphthyridine derivatives. Anti-cancer Agents Med. Chem: 2007; 7 685 709 (Pubitemid 350237773)
-
(2007)
Anti-Cancer Agents in Medicinal Chemistry
, vol.7
, Issue.6
, pp. 685-709
-
-
Srivastava, S.K.1
Jha, A.2
Agarwal, S.K.3
Mukherjee, R.4
Burman, A.C.5
-
14
-
-
33745955860
-
Impact of genetic diagnostics on drug development strategy
-
Millon R. P. Impact of genetic diagnostics on drug development strategy. Nat. Rev: 2006; 5 459 462
-
(2006)
Nat. Rev
, vol.5
, pp. 459-462
-
-
Millon, R.P.1
-
15
-
-
0033861369
-
Synthesis and cytotoxicity of 2-methyl-1-substituted-imidazo [4,5-g]quinoline-4,9-dione and 7,8-dihydro-10H-1,4]oxazino[3',4':2,3]imidazo[4, 5-g]quinoline-5,12-dio ne derivatives
-
Suh M. E., Kang M. J., Yoo H. W. et al. Synthesis and cytotoxicity of 2-methyl-1-substituted-imidazo [4,5-g]quinoline-4,9-dione and 7,8-dihydro-10H-1,4]oxazino[3',4':2,3]imidazo[4,5-g]quinoline-5,12-dio ne derivatives. Bioorg Med Chem: 2000; 8 2079 2083
-
(2000)
Bioorg Med Chem
, vol.8
, pp. 2079-2083
-
-
Suh, M.E.1
Kang, M.J.2
Yoo, H.W.3
-
16
-
-
41349085423
-
Synthesis of novel 4,6-disubstituted quinazoline derivatives, their anti-inflammatory and anti-cancer activity (cytotoxic) against U937 leukemia cell lines
-
DOI 10.1016/j.ejmech.2007.06.010, PII S0223523407002607
-
Chandrika P. M., Yakaiah T., Rao A. R. et al. Synthesis of novel 4, 6-disubstituted quinazoline derivatives, their anti-inflammatory and anti-cancer activity (cytotoxic) against U937 leukemia cell lines. Eur J Med Chem: 2008; 43 846 852 (Pubitemid 351447327)
-
(2008)
European Journal of Medicinal Chemistry
, vol.43
, Issue.4
, pp. 846-852
-
-
Chandrika, P.M.1
Yakaiah, T.2
Rao, A.R.R.3
Narsaiah, B.4
Reddy, N.C.5
Sridhar, V.6
Rao, J.V.7
-
17
-
-
0642340255
-
Effects of lipophilicity on the affinity and nonspecific binding of iodinated benzothiazole derivatives
-
Yanming W., Chester A. M., Guo-Feng H. et al. Effects of lipophilicity on the affinity and nonspecific binding of iodinated benzothiazole derivatives. J mol neurosci: 2003; 20 255 260
-
(2003)
J Mol Neurosci
, vol.20
, pp. 255-260
-
-
Yanming, W.1
Chester, A.M.2
Guo-Feng, H.3
-
18
-
-
0022344490
-
Quantitative chemical structure - pharmacokinetic data relationships. IV. Relationships between pharmacokinetic data and lipophilicity of iodine-substituted aromatic and arylaliphatic compounds
-
Laznicek M., Beno P., Waisser K. et al. Quantitative chemical structure-pharmacokinetic data relationships. IV. Relationships between pharmacokinetic data and lipophilicity of iodine-substituted aromatic and arylaliphatic compounds. Cesko-Slovenska Farmacie: 1985; 34 353 358 (Pubitemid 16173950)
-
(1985)
Cesko-Slovenska Farmacie
, vol.34
, Issue.9
, pp. 353-358
-
-
Laznicek, M.1
Beno, P.2
Waisser, K.3
Kvetina, J.4
-
19
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods: 1983; 65 55 63 (Pubitemid 14203433)
-
(1983)
Journal of Immunological Methods
, vol.65
, Issue.1-2
, pp. 55-63
-
-
Mosmann, T.1
-
20
-
-
84873769112
-
Anti-inflammatory and antipyretic activities of indomethacin, 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
-
Winter C. A., Risley E. A., Nuss G. W. Anti-inflammatory and antipyretic activities of indomethacin, 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3- acetic acid. J Pharmacol Exp Ther: 1963; 141 369 376
-
(1963)
J Pharmacol Exp Ther
, vol.141
, pp. 369-376
-
-
Winter, C.A.1
Risley, E.A.2
Nuss, G.W.3
-
21
-
-
1942518042
-
Pharmacology and biochemical evaluation of Tridax Procumbens on infl ammation
-
Diwan P. V., Karwande I., Margaret I. et al. Pharmacology and biochemical evaluation of Tridax Procumbens on infl ammation. Indian J Pharmacol: 1989; 21 101 105
-
(1989)
Indian J Pharmacol
, vol.21
, pp. 101-105
-
-
Diwan, P.V.1
Karwande, I.2
Margaret, I.3
-
23
-
-
49149147973
-
Iterative partial equalization of orbital electronegativity - A rapid access to atomic charges
-
Gasteiger J., Marsili M. Iterative partial equalization of orbital electronegativity - A rapid access to atomic charges. Tetrahedron: 1980; 36 3219 3228
-
(1980)
Tetrahedron
, vol.36
, pp. 3219-3228
-
-
Gasteiger, J.1
Marsili, M.2
|