Pragmatic trials of complex psychosocial interventions: Methodological challenges

Epidemiology and Psychiatric Sciences

Volumn 22, Issue 2, 2013, Pages 105-109

  Dunn, G ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

intention to treat analysis; pragmatic trials; psychosocial interventions; statistics

Indexed keywords

FOLLOW UP; HEALTH CARE; HEALTH SERVICE; HOSPITAL ADMISSION; HUMAN; PATIENT CARE; PSYCHOSOCIAL CARE; QUALITY OF LIFE; REVIEW; SOCIAL INTERACTION; TREATMENT REFUSAL; CLUSTER ANALYSIS; HEALTH CARE PERSONNEL;

CLUSTER ANALYSIS; HEALTH PERSONNEL; HUMANS;

EID: 84877758713     PISSN: 20457960     EISSN: 20457979     Source Type: Journal    
DOI: 10.1017/S2045796013000048     Document Type: Review

References (17)

1. Angrist JD, Imbens GW, Rubin DB (1996). Identification of causal effects using instrumental variables (with discussion). Journal of the American Statistical Association 91, 444-455.
2. Bloom HS (1984). Accounting for no-shows in experimental evaluation designs. Evaluation Review 8, 225-246.
3. Creed F, Mbaya P, Lancashire S, Tomenson B, Williams B, Holme S (1997). Cost effectiveness of day and inpatient psychiatric treatment: results of a randomized controlled trial. British Medical Journal 314, 1381-1385.
4. Donner A, Klar N (2000). Design and Analysis of Cluster Randomised Trials in Health Research. Edward Arnold: London.
5. Dowrick CF, Dunn G, Ayuso-Mateos J-L, Dalgard OS, Page H, Lehtinen V, Casey P, Wilkinson C, Vázquez-Barquero J-L, Wilkinson G, the ODIN Group (2000). Problem-solving treatment and group psycho-education for depression: a multicentre randomized controlled trial. British Medical Journal 321, 1450-1454.
6. Dunn G, Bentall R (2007). Modelling treatment-effect heterogeneity in randomized controlled trials of complex interventions (psychological treatments). Statistics in Medicine 26, 4719-4745.
7. Dunn G, Maracy M, Dowrick C, Ayuso-Mateos JL, Dalgard OS, Page H, Lehtinen V, Casey P, Wilkinson C, Vázquez-Barquero JL, Wilkinson G, and The Outcomes of Depression International (ODIN) Group (2003). Estimating psychological treatment effects from an RCT with both non-compliance and loss to follow-up. British Journal of Psychiatry 183, 323-331.
8. Dunn G, Maracy M, Tomenson B (2005). Estimating treatment effects from randomized clinical trials with non-compliance and loss to follow-up: the role of instrumental variable methods. Statistical Methods in Medical Research 14, 369-395.
9. Emsley R, White IR, Dunn G (2010). Mediation and moderation of treatment effects in randomised controlled trials of complex interventions. Statistical Methods in Medical Research 19, 237-270.
10. Frangakis CE, Rubin DB (1999). Addressing complications of intention-to-treat analysis in the combined presence of all-or-none treatment noncompliance and subsequent missing outcomes. Biometrika 86, 365-379.
11. Jo B, Asparouhov T, Muthén BO (2008a). Intention-to-treat analysis in cluster randomized trials with noncompliance. Statistics in Medicine 27, 5565-5577.
12. Jo B, Asparouhov T, Muthén BO, Ialongo NS, Brown CH (2008b). Cluster randomized trials with treatment noncompliance. Psychological Methods 13, 1-18.
13. Roberts C, Roberts S (2005). The analysis of clinical trials with clustering effects due to treatment. Clinical Trials 2, 152-162.
14. Schochet PZ, Chiang HS (2011). Estimation and identification of the complier average causal effect parameter in education RCTs. Journal of Educational and Behavioral Statistics 36, 307-345.
15. Schwartz D, Lellouch J (1967). Explanatory and pragmatic attitudes in therapeutic trials. Journal of Chronic Disease 20, 637-648.
16. Sommer A, Zeger SL (1991). On estimating efficacy from clinical trials. Statistics in Medicine 10, 45-52.
17. Spitzer WO, Feinstein AR, Sackett DL (1975). What is a health care trial? Journal of the American Medical Association 233, 161-163.