A case of Epstein-Barr virus-related lymphadenopathy mimicking the clinical features of IgG4-related disease

Modern Rheumatology

Volumn 23, Issue 3, 2013, Pages 597-603

  Wada, Yoko ^a   Kojima, Masaru ^b   Yoshita, Kazuhiro ^a   Yamazaki, Mihoko ^a   Kobayashi, Daisuke ^a   Murakami, Shuichi ^a   Nishi, Shinichi ^c   Nakano, Masaaki ^d   Narita, Ichiei ^a  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^b DOKKYO MEDICAL UNIVERSITY   (Japan)

^c KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d NIIGATA UNIVERSITY   (Japan)

Author keywords

Bronchial asthma; Epstein Barr virus; IgG4 related disease; Membranous nephropathy; Systemic lymphadenopathy

Indexed keywords

ANTINUCLEAR ANTIBODY; C REACTIVE PROTEIN; COMPLEMENT COMPONENT C3C; CYTOMEGALOVIRUS ANTIBODY; GALLIUM; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G4; LOSARTAN; RHEUMATOID FACTOR;

AGED; ANTIBODY DETECTION; ARTICLE; AXILLARY LYMPH NODE; CASE REPORT; CERVICAL LYMPH NODE; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; EDEMA; ELECTRON MICROSCOPY; EPSTEIN BARR VIRUS INFECTION; FEMALE; GLOMERULUS BASEMENT MEMBRANE; GLOMERULUS CAPILLARY; HUMAN; HYPERGAMMAGLOBULINEMIA; IMMUNOFLUORESCENCE; IMMUNOGLOBULIN BLOOD LEVEL; IN SITU HYBRIDIZATION; JAPANESE; KIDNEY BIOPSY; LOW DRUG DOSE; LUNG FUNCTION; LYMPH NODE BIOPSY; LYMPHADENOPATHY; LYMPHOCYTIC INFILTRATION; PHYSICAL EXAMINATION; PLASMA CELL; PRIORITY JOURNAL; PROLIFERATIVE GLOMERULONEPHRITIS; PROTEIN BLOOD LEVEL; PROTEIN URINE LEVEL; PROTEINURIA; SWELLING; THROMBOCYTOPENIA; VIRUS LATENCY;

AGED; DIAGNOSIS, DIFFERENTIAL; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; HUMANS; HYPERGAMMAGLOBULINEMIA; IMMUNOGLOBULIN G; LYMPHATIC DISEASES;

EID: 84877748731     PISSN: 14397595     EISSN: 14397609     Source Type: Journal    
DOI: 10.1007/s10165-012-0695-9     Document Type: Article

References (24)

1. Masaki Y, Dong L, Kurose N, Kitagawa K, Morikawa Y, Yamamoto H, et al. Proposal for a new clinical entity, IgG4-positive multi-organ lymphoproliferative syndrome: analysis of 64 cases of IgG4-related disorders. Ann Rheum Dis. 2009;68:1310-5.
2. Umehara H, Kazuichi O, Masaki Y, Kawano M, Yamamoto M, Saeki T, et al. A novel clinical entity, IgG4-related disease (IgG4RD): general concept and details. Mod Rheumatol. 2012;22:1-14.
3. Hamano H, Kawa S, Horiuchi A, Unno H, Furuya N, Akamatsu T, et al. High serum IgG4 concentrations in patients with sclerosing pancreatitis. N Engl J Med. 2001;344:732-8.
4. Zen Y, Sawazaki A, Miyayama S, Notsumata K, Tanaka N, Nakanuma Y. A case of retroperitoneal and mediastinal fibrosis exhibiting elevated levels of IgG4 in the absence of sclerosing pancreatitis (autoimmune pancreatitis). Hum Pathol. 2006;37:239-43.
5. Yamamoto M, Takahashi H, Ohara M, Suzuki C, Naishiro Y, Yamamoto H, et al. A new conceptualization for Mikulicz's disease as an IgG4-related plasmacytic disease. Mod Rheumatol. 2006;16:335-40.
6. Umehara H, Okazaki K, Masaki Y, Kawano M, Yamamoto M, Saeki T, et al. Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011. Mod Rheumatol. 2012;22:21-30.
7. Yamamoto M, Tabeya T, Naishiro Y, Yajima H, Ishigami K, Shimizu Y, et al. Value of serum IgG4 in the diagnosis of IgG4-related disease and in differentiation from rheumatic diseases and other diseases. Mod Rheumatol. 2011 (Epub ahead of print).
8. Iguchi A, Wada Y, Kobayashi D, Sato H, Oyama T, Nakatsue T, et al. A case of MPO and PR3-ANCA-positive hypertrophic cranial pachymeningitis with elevated serum IgG4. Mod Rheumatol. 2012 (in press).
9. Shacks SJ, Heiner DC, Bahna SL, Horwitz CA. Increased serum IgG4 levels in acute Epstein-Barr viral mononucleosis. Ann Allergy. 1985;54:284-8.
10. Okazaki K, Uchida K, Fukui T. Recent advances in autoimmune pancreatitis: concept, diagnosis, and pathogenesis. J Gastroenterol. 2008;43:409-18.
11. Kountouras J, Zavos C, Chatzopoulos D. A concept on the role of Helicobacter pylori infection in autoimmune pancreatitis. J Cell Mol Med. 2005;9:196-207.
12. Kurth J, Hansmann M-L, Rajewsky K, Küppers R. Epstein-Barr virus infected B cells expanding in germinal centers of infectious mononucleosis patients do not participate in germinal center reaction. Proc Natl Acad Sci USA. 2003;100:4730-5.
13. Poole BD, Scofield RH, Harley JB, James JA. Epstein-Barr virus and molecular mimicry in systemic lupus erythematosus. Autoimmunity. 2006;39:63-70.
14. Toussirot E, Roudier J. Epstein-Barr virus in autoimmune diseases. Best Pract Res Clin Rheumatol. 2008;22:883-96.
15. Niller HH, Wolf H, Minarovits J. Regulation and dysregulation of Epstein-Barr virus latency: implications for the development of autoimmune diseases. Autoimmunity. 2008;41:298-328.
16. Kashiwagi S, Kumasaka T, Bunsei N, Fukumura Y, Yamasaki S, Abe K, et al. Detection of Epstein-Barr virus-encoded small RNA-expressed myofibroblasts and IgG4-producing plasma cells in sclerosing angiomatoid nodular transformation of the spleen. Virchows Arch. 2008;453:275-82.
17. Kojima M, Sugiura I, Itoh H, Shimizu K, Murayama K, Motoori T, et al. Histological varieties of Epstein-Barr virus related lymph node lesion resembling autoimmune disease-like clinicopathological findings in middle-aged and elderly patients - a study of six cases. Pathol Res Pract. 2006;203:609-15.
18. Blowey DL. Nephrotic syndrome associated with an Epstein-Barr virus infection. Pediatr Nephrol. 1996;10:507-8.
19. Araya CE, Gonzalez-Peralta RP, Skoda-Smith S, Dharnidharka VR. Systemic Epstein-Barr virus infection associated with membranous nephropathy in children. Clin Nephrol. 2006;65:160-4.
20. Saeki T, Imai N, Ito T, Yamazaki H, Nishi S. Membranous nephropathy associated with IgG4-related systemic disease and without autoimmune pancreatitis. Clin Nephrol. 2009;71:173-8.
21. Nishi S, Imai N, Yoshita K, Ito Y, Saeki T. Clinicopathological findings of immunoglobulin G4-related kidney disease. Clin Exp Nephrol. 2011;15:810-9.
22. Stone JH, Zen Y, Deshpande V. IgG4-related disease. N Engl J Med. 2012;366:539-51.
23. Kuroki A, Iyoda M, Shibata T, Sugisaki T. Th2 cytokines increase and stimulate B cells to produce IgG4 in idiopathic membranous nephropathy. Kidney Int. 2005;68:302-10.
24. Ohshima K, Karube K, Hamasaki M, Tutiya T, Yamaguchi T, Suefuji H, et al. Differential chemokine, chemokine receptor and cytokine expression in Epstein-Barr virus-associated lymphoproliferative diseases. Leuk Lymphoma. 2003;44:1367-78.