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Volumn 15, Issue 2, 2013, Pages 310-323

Neurotoxicity and reactive astrogliosis in the anterior cingulate cortex in acute ciguatera poisoning

Author keywords

Anterior cingulate cortex; Ciguatoxin; Neurotoxicity; Reactive astrogliosis; Synaptic plasticity

Indexed keywords

CIGUATOXIN; CONNEXIN 43; EXCITATORY AMINO ACID TRANSPORTER 2; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SODIUM CHANNEL;

EID: 84877742621     PISSN: 15351084     EISSN: 15591174     Source Type: Journal    
DOI: 10.1007/s12017-013-8220-7     Document Type: Article
Times cited : (20)

References (49)
  • 1
    • 0029984320 scopus 로고    scopus 로고
    • Metaplasticity: The plasticity of synaptic plasticity
    • 8658594 10.1016/S0166-2236(96)80018-X 1:CAS:528:DyaK28XhvFGgt70%3D
    • Abraham, W. C.; & Bear, M. F. (1996). Metaplasticity: The plasticity of synaptic plasticity. Trends in Neurosciences, 19, 126-130.
    • (1996) Trends in Neurosciences , vol.19 , pp. 126-130
    • Abraham, W.C.1    Bear, M.F.2
  • 2
    • 79551591722 scopus 로고    scopus 로고
    • Astrocyte-neuron metabolic relationships: For better and for worse
    • 21236501 10.1016/j.tins.2010.12.001 1:CAS:528:DC%2BC3MXhsFyisb0%3D
    • Allaman, I.; Bélanger, M.; & Magistretti, P. J. (2011). Astrocyte-neuron metabolic relationships: For better and for worse. Trends in Neurosciences, 34(2), 76-87.
    • (2011) Trends in Neurosciences , vol.34 , Issue.2 , pp. 76-87
    • Allaman, I.1    Bélanger, M.2    Magistretti, P.J.3
  • 3
    • 1642447155 scopus 로고    scopus 로고
    • A pilot study of the cognitive and psychological correlates of chronic ciguatera fish poisoning
    • 10.1016/j.hal.2003.08.006
    • Arena, P.; Levin, B.; Fleming, L. E.; Friedman, M. A.; & Blythe, D. (2004). A pilot study of the cognitive and psychological correlates of chronic ciguatera fish poisoning. Harmful Algae, 3, 51-60.
    • (2004) Harmful Algae , vol.3 , pp. 51-60
    • Arena, P.1    Levin, B.2    Fleming, L.E.3    Friedman, M.A.4    Blythe, D.5
  • 4
    • 0028356548 scopus 로고
    • Synaptic plasticity: LTP and LTD
    • 7919934 10.1016/0959-4388(94)90101-5 1:STN:280:DyaK2M%2FgtlKmsw%3D%3D
    • Bear, M. F.; & Malenka, R. C. (1994). Synaptic plasticity: LTP and LTD. Current Opinion in Neurobiology, 4, 389-399.
    • (1994) Current Opinion in Neurobiology , vol.4 , pp. 389-399
    • Bear, M.F.1    Malenka, R.C.2
  • 5
    • 79955476120 scopus 로고    scopus 로고
    • Toxicokinetics of the ciguatoxin P-CTX-1 in rats after intraperitoneal or oral administration
    • 21349314 10.1016/j.tox.2011.02.005
    • Bottein, M. Y.; Wang, Z.; & Ramsdell, J. S. (2011). Toxicokinetics of the ciguatoxin P-CTX-1 in rats after intraperitoneal or oral administration. Toxicology, 284, 1-6.
    • (2011) Toxicology , vol.284 , pp. 1-6
    • Bottein, M.Y.1    Wang, Z.2    Ramsdell, J.S.3
  • 7
    • 38649114357 scopus 로고    scopus 로고
    • Anterior cingulate cortex modulates visceral pain as measured by visceromotor responses in viscerally hypersensitive rats
    • 18242219 10.1053/j.gastro.2007.11.057 1:CAS:528:DC%2BD1cXivFOjsrs%3D
    • Cao, Z.; Wu, X.; Chen, S.; Fan, J.; Zhang, R.; Owyang, C.; et al. (2008). Anterior cingulate cortex modulates visceral pain as measured by visceromotor responses in viscerally hypersensitive rats. Gastroenterology, 134, 535-543.
    • (2008) Gastroenterology , vol.134 , pp. 535-543
    • Cao, Z.1    Wu, X.2    Chen, S.3    Fan, J.4    Zhang, R.5    Owyang, C.6    Li, Y.7
  • 9
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • 11369436 10.1016/S0301-0082(00)00067-8 1:CAS:528:DC%2BD3MXjsFWns74%3D
    • Danbolt, N. C. (2001). Glutamate uptake. Progress in Neurobiology, 65, 1-105.
    • (2001) Progress in Neurobiology , vol.65 , pp. 1-105
    • Danbolt, N.C.1
  • 10
    • 0032890031 scopus 로고    scopus 로고
    • Ciguatoxins and brevetoxins, neurotoxic polyether compounds active on sodium channels
    • 9920485 10.1016/S0041-0101(98)00169-X 1:CAS:528:DyaK1cXnvF2lt74%3D
    • Dechraoui, M. Y.; Naar, J.; Pauillac, S.; & Legrand, A. M. (1999). Ciguatoxins and brevetoxins, neurotoxic polyether compounds active on sodium channels. Toxicon, 37, 125-143.
    • (1999) Toxicon , vol.37 , pp. 125-143
    • Dechraoui, M.Y.1    Naar, J.2    Pauillac, S.3    Legrand, A.M.4
  • 12
    • 65249146676 scopus 로고    scopus 로고
    • Up-regulation of anterior cingulate cortex NR2B receptors contributes to visceral pain responses in rats
    • 19208366 10.1053/j.gastro.2009.01.069 1:CAS:528:DC%2BD1MXmtFajsrw%3D
    • Fan, J.; Wu, X.; Cao, Z.; Chen, S.; Owyang, C.; & Li, Y. (2009). Up-regulation of anterior cingulate cortex NR2B receptors contributes to visceral pain responses in rats. Gastroenterology, 136(5), 1732-1740.
    • (2009) Gastroenterology , vol.136 , Issue.5 , pp. 1732-1740
    • Fan, J.1    Wu, X.2    Cao, Z.3    Chen, S.4    Owyang, C.5    Li, Y.6
  • 13
    • 33645902488 scopus 로고    scopus 로고
    • Enhanced responses of the anterior cingulate cortex neurones to colonic distension in viscerally hypersensitive rats
    • 16239277 10.1113/jphysiol.2005.096073 1:CAS:528:DC%2BD28Xlt1Sgug%3D%3D
    • Gao, J.; Wu, X.; Owyang, C.; & Li, Y. (2006). Enhanced responses of the anterior cingulate cortex neurones to colonic distension in viscerally hypersensitive rats. Journal of Physiology, 570, 169-183.
    • (2006) Journal of Physiology , vol.570 , pp. 169-183
    • Gao, J.1    Wu, X.2    Owyang, C.3    Li, Y.4
  • 14
    • 0033783707 scopus 로고    scopus 로고
    • Excitable properties in astrocytes derived from human embryonic CNS stem cells
    • 11029624 10.1046/j.1460-9568.2000.00234.x 1:STN:280: DC%2BD3M%2FjtlensQ%3D%3D
    • Gritti, A.; Rosati, B.; Lecchi, M.; Vescovi, A. L.; & Wanke, E. (2000). Excitable properties in astrocytes derived from human embryonic CNS stem cells. European Journal of Neuroscience, 12, 3549-3559.
    • (2000) European Journal of Neuroscience , vol.12 , pp. 3549-3559
    • Gritti, A.1    Rosati, B.2    Lecchi, M.3    Vescovi, A.L.4    Wanke, E.5
  • 15
    • 0028838068 scopus 로고
    • Long-term potentiation and depression of synaptic transmission in rat posterior cingulate cortex
    • 7743185 10.1016/0006-8993(94)01254-F 1:CAS:528:DyaK2MXjvVyjsLk%3D
    • Hedberg, T. G.; & Stanton, P. K. (1995). Long-term potentiation and depression of synaptic transmission in rat posterior cingulate cortex. Brain Research, 670, 181-196.
    • (1995) Brain Research , vol.670 , pp. 181-196
    • Hedberg, T.G.1    Stanton, P.K.2
  • 16
    • 0036979007 scopus 로고    scopus 로고
    • Ciguatoxin-induced oscillations in membrane potential and action potential firing in rat parasympathetic neurons
    • 12169106 10.1046/j.1460-9568.2002.02071.x 1:STN:280: DC%2BD38vhsFCltw%3D%3D
    • Hogg, R. C.; Lewis, R. J.; & Adams, D. J. (2002). Ciguatoxin-induced oscillations in membrane potential and action potential firing in rat parasympathetic neurons. European Journal of Neuroscience, 16, 242-248.
    • (2002) European Journal of Neuroscience , vol.16 , pp. 242-248
    • Hogg, R.C.1    Lewis, R.J.2    Adams, D.J.3
  • 19
    • 0026458124 scopus 로고
    • Primary structure and functional characterization of a high-affinity glutamate transporter
    • 1280334 10.1038/360467a0 1:CAS:528:DyaK3sXltV2itbY%3D
    • Kanai, Y.; & Hediger, M. A. (1992). Primary structure and functional characterization of a high-affinity glutamate transporter. Nature, 360, 467-471.
    • (1992) Nature , vol.360 , pp. 467-471
    • Kanai, Y.1    Hediger, M.A.2
  • 20
    • 0034696314 scopus 로고    scopus 로고
    • Three clusters of ciguatera poisoning: Clinical manifestations and public health implications
    • 10772586 1:STN:280:DC%2BD3c3jtlGmsg%3D%3D
    • Karalis, T.; Gupta, L.; Chu, M.; Campbell, B. A.; Capra, M. F.; & Maywood, P. A. (2000). Three clusters of ciguatera poisoning: Clinical manifestations and public health implications. Medical Journal of Australia, 172(4), 160-162.
    • (2000) Medical Journal of Australia , vol.172 , Issue.4 , pp. 160-162
    • Karalis, T.1    Gupta, L.2    Chu, M.3    Campbell, B.A.4    Capra, M.F.5    Maywood, P.A.6
  • 22
    • 0034332886 scopus 로고    scopus 로고
    • Ciguatera: Recent advances but the risk remains
    • 11078162 10.1016/S0168-1605(00)00382-2 1:CAS:528:DC%2BD3cXosFKhtbo%3D
    • Lehane, L.; & Lewis, R. J. (2000). Ciguatera: Recent advances but the risk remains. International Journal of Food Microbiology, 61, 91-125.
    • (2000) International Journal of Food Microbiology , vol.61 , pp. 91-125
    • Lehane, L.1    Lewis, R.J.2
  • 23
    • 40049111522 scopus 로고    scopus 로고
    • Repeat exposure to ciguatoxin leads to enhanced and sustained thermoregulatory, pain threshold and motor activity responses in mice: Relationship to blood ciguatoxin concentrations
    • 18280027 10.1016/j.tox.2007.12.013
    • Levin, E. D.; & Ramsdell, J. S. (2008). Repeat exposure to ciguatoxin leads to enhanced and sustained thermoregulatory, pain threshold and motor activity responses in mice: Relationship to blood ciguatoxin concentrations. Toxicology, 246, 55-62.
    • (2008) Toxicology , vol.246 , pp. 55-62
    • Levin, E.D.1    Ramsdell, J.S.2
  • 24
    • 0142212162 scopus 로고    scopus 로고
    • Hypothalamic regulation of pancreatic secretion is mediated by central cholinergic pathway in rat
    • 10.1113/jphysiol.2003.049122 1:CAS:528:DC%2BD3sXps1ehurc%3D
    • Li, Y.; Wu, X. Y.; Zhu, J. X.; & Owyang, C. (2003). Hypothalamic regulation of pancreatic secretion is mediated by central cholinergic pathway in rat. The Journal of Physiology (London), 552, 571-587.
    • (2003) The Journal of Physiology (London) , vol.552 , pp. 571-587
    • Li, Y.1    Wu, X.Y.2    Zhu, J.X.3    Owyang, C.4
  • 25
    • 84859756850 scopus 로고    scopus 로고
    • Phosphorylated CaMKII postsynaptic binding to NR2B subunits in the anterior cingulate cortex mediates visceral pain in visceral hypersensitive rats
    • 22380661 10.1111/j.1471-4159.2012.07717.x 1:CAS:528:DC%2BC38Xmsl2hsrc%3D
    • Li, Y.; Zhang, X.; Liu, H.; Cao, Z.; Chen, S.; Cao, B.; et al. (2012). Phosphorylated CaMKII postsynaptic binding to NR2B subunits in the anterior cingulate cortex mediates visceral pain in visceral hypersensitive rats. Journal of Neurochemistry, 121(4), 662-671.
    • (2012) Journal of Neurochemistry , vol.121 , Issue.4 , pp. 662-671
    • Li, Y.1    Zhang, X.2    Liu, H.3    Cao, Z.4    Chen, S.5    Cao, B.6    Liu, J.7
  • 26
    • 66149114824 scopus 로고    scopus 로고
    • Neurological picture. Reversible corpus callosum lesion in ciguatera poisoning
    • 10.1136/jnnp.2008.161786
    • Liang, C. K.; Lo, Y. K.; Li, J. Y.; & Lai, P. H. (2009). Neurological picture. Reversible corpus callosum lesion in ciguatera poisoning. Journal of Neurology, Neurosurgery and Psychiatry, 80(6), 587-588.
    • (2009) Journal of Neurology, Neurosurgery and Psychiatry , vol.80 , Issue.6 , pp. 587-588
    • Liang, C.K.1    Lo, Y.K.2    Li, J.Y.3    Lai, P.H.4
  • 27
    • 0033558371 scopus 로고    scopus 로고
    • Neurotoxins targeting receptor site 5 of voltage-dependent sodium channels increase the nodal volume of myelinated axons
    • 10220108 10.1002/(SICI)1097-4547(19990315)55:6<666: AID-JNR2>3.0.CO;2-H 1:CAS:528:DyaK1MXisVKku7c%3D
    • Mattei, C.; Dechraoui, M. Y.; Molgo, J.; Meunier, F. A.; Legrand, A. M.; & Benoit, E. (1999). Neurotoxins targeting receptor site 5 of voltage-dependent sodium channels increase the nodal volume of myelinated axons. Journal of Neuroscience Research, 55, 666-673.
    • (1999) Journal of Neuroscience Research , vol.55 , pp. 666-673
    • Mattei, C.1    Dechraoui, M.Y.2    Molgo, J.3    Meunier, F.A.4    Legrand, A.M.5    Benoit, E.6
  • 28
    • 0025271664 scopus 로고
    • Ciguatoxin enhances quantal transmitter release from frog motor nerve terminals
    • 1972891 10.1111/j.1476-5381.1990.tb12991.x 1:CAS:528:DyaK3cXhvFemsLs%3D
    • Molgo, J.; Comella, J. X.; & Legrand, A. M. (1990). Ciguatoxin enhances quantal transmitter release from frog motor nerve terminals. British Journal of Pharmacology, 99, 695-700.
    • (1990) British Journal of Pharmacology , vol.99 , pp. 695-700
    • Molgo, J.1    Comella, J.X.2    Legrand, A.M.3
  • 29
    • 0028212163 scopus 로고
    • Direct signaling from astrocytes to neurons in cultures of mammalian brain cells
    • 8134839 10.1126/science.8134839 1:CAS:528:DyaK2cXisVWht70%3D
    • Nedergaard, M. (1994). Direct signaling from astrocytes to neurons in cultures of mammalian brain cells. Science, 263, 1768-7171.
    • (1994) Science , vol.263 , pp. 1768-7171
    • Nedergaard, M.1
  • 30
    • 0025370632 scopus 로고
    • Visceral pain: A review of experimental studies
    • 2195438 10.1016/0304-3959(90)90021-5 1:STN:280:DyaK3czhtVGnug%3D%3D
    • Ness, T. J.; & Gebhart, G. F. (1990). Visceral pain: A review of experimental studies. Pain, 41, 167-234.
    • (1990) Pain , vol.41 , pp. 167-234
    • Ness, T.J.1    Gebhart, G.F.2
  • 33
    • 0028833561 scopus 로고
    • Neuroexcitatory actions of ciguatoxin on brain regions associated with thermoregulation
    • 7756616 10.1097/00001756-199501000-00020 1:CAS:528:DyaK2MXks1agu7w%3D
    • Peng, Y. G.; Taylor, T. B.; Finch, R. E.; Moeller, P. D.; & Ramsdell, J. S. (1995). Neuroexcitatory actions of ciguatoxin on brain regions associated with thermoregulation. NeuroReport, 6, 305-309.
    • (1995) NeuroReport , vol.6 , pp. 305-309
    • Peng, Y.G.1    Taylor, T.B.2    Finch, R.E.3    Moeller, P.D.4    Ramsdell, J.S.5
  • 35
    • 33644519960 scopus 로고    scopus 로고
    • Astrocyte dysfunction in neurological disorders: A molecular perspective
    • 16495941 10.1038/nrn1870 1:CAS:528:DC%2BD28Xhs1Gqt7g%3D
    • Seifert, G.; Schilling, K.; & Steinhauser, C. (2006). Astrocyte dysfunction in neurological disorders: A molecular perspective. Nature Reviews Neuroscience, 7, 194-206.
    • (2006) Nature Reviews Neuroscience , vol.7 , pp. 194-206
    • Seifert, G.1    Schilling, K.2    Steinhauser, C.3
  • 36
    • 70449678738 scopus 로고    scopus 로고
    • Molecular dissection of reactive astrogliosis and glial scar formation
    • 19782411 10.1016/j.tins.2009.08.002 1:CAS:528:DC%2BD1MXhsVKgs7bP
    • Sofroniew, M. V. (2009). Molecular dissection of reactive astrogliosis and glial scar formation. Trends in Neurosciences, 32, 638-647.
    • (2009) Trends in Neurosciences , vol.32 , pp. 638-647
    • Sofroniew, M.V.1
  • 37
    • 0030221741 scopus 로고    scopus 로고
    • + channels in glia: Properties and possible functions
    • 8843601 10.1016/0166-2236(96)10039-4 1:CAS:528:DyaK28XkvFWitr0%3D
    • + channels in glia: Properties and possible functions. Trends in Neurosciences, 19, 325-331.
    • (1996) Trends in Neurosciences , vol.19 , pp. 325-331
    • Sontheimer, H.1    Black, J.A.2    Waxman, S.G.3
  • 39
    • 79957578276 scopus 로고    scopus 로고
    • Proteomic modification in gills and brains of medaka fish (Oryzias melastigma) after exposure to a sodium channel activator neurotoxin, brevetoxin-1
    • 21632025 10.1016/j.aquatox.2011.04.019 1:CAS:528:DC%2BC3MXnslKitb4%3D
    • Tian, L.; Wang, M.; Li, X.; Lam, P. K.; Wang, D.; Chou, H. N.; et al. (2011). Proteomic modification in gills and brains of medaka fish (Oryzias melastigma) after exposure to a sodium channel activator neurotoxin, brevetoxin-1. Aquatic Toxicology, 104, 211-217.
    • (2011) Aquatic Toxicology , vol.104 , pp. 211-217
    • Tian, L.1    Wang, M.2    Li, X.3    Lam, P.K.4    Wang, D.5    Chou, H.N.6    Li, Y.7    Chan, L.L.8
  • 41
    • 23044435896 scopus 로고    scopus 로고
    • Astrocytes, from brain glue to communication elements: The revolution continues
    • 16025096 10.1038/nrn1722 1:CAS:528:DC%2BD2MXmvVGht7Y%3D
    • Volterra, A.; & Meldolesi, J. (2005). Astrocytes, from brain glue to communication elements: The revolution continues. Nature Reviews Neuroscience, 6, 626-640.
    • (2005) Nature Reviews Neuroscience , vol.6 , pp. 626-640
    • Volterra, A.1    Meldolesi, J.2
  • 42
    • 0033232909 scopus 로고    scopus 로고
    • Loss of synaptic depression in mammalian anterior cingulate cortex after amputation
    • 10531439 1:CAS:528:DyaK1MXnslyitLg%3D
    • Wei, F.; Li, P.; & Zhuo, M. (1999). Loss of synaptic depression in mammalian anterior cingulate cortex after amputation. Journal of Neuroscience, 19, 9346-9354.
    • (1999) Journal of Neuroscience , vol.19 , pp. 9346-9354
    • Wei, F.1    Li, P.2    Zhuo, M.3
  • 43
    • 0035339090 scopus 로고    scopus 로고
    • Potentiation of sensory responses in the anterior cingulate cortex following digit amputation in the anaesthetised rat
    • 11313449 10.1111/j.1469-7793.2001.0823e.x 1:CAS:528:DC%2BD3MXjslCgur4%3D
    • Wei, F.; & Zhuo, M. (2001). Potentiation of sensory responses in the anterior cingulate cortex following digit amputation in the anaesthetised rat. Journal of Physiology, 532, 823-833.
    • (2001) Journal of Physiology , vol.532 , pp. 823-833
    • Wei, F.1    Zhuo, M.2
  • 44
    • 84891633339 scopus 로고    scopus 로고
    • Stimulation of the medial thalamus-anterior cingulate cortex synapses is important for learning and triggering pain memories in visceral hypersensitive states
    • Wu, X. Y.; Fan, J.; Cao, Z.; Chen, S.; Owyang C.; & Li, Y. (2008b). Stimulation of the medial thalamus-anterior cingulate cortex synapses is important for learning and triggering pain memories in visceral hypersensitive states. Gastroenterology, 134(S1), A 562.
    • (2008) Gastroenterology , vol.134 , Issue.S1
    • Wu, X.Y.1    Fan, J.2    Cao, Z.3    Chen, S.4    Owyang, C.5    Li, Y.6
  • 45
    • 42049112756 scopus 로고    scopus 로고
    • Role for NMDA receptors in visceral nociceptive transmission in the anterior cingulate cortex of viscerally hypersensitive rats
    • 18258793 10.1152/ajpgi.00452.2007 1:CAS:528:DC%2BD1cXkslOrtrc%3D
    • Wu, X.; Gao, J.; Yan, J.; Fan, J.; Owyang, C.; & Li, Y. (2008a). Role for NMDA receptors in visceral nociceptive transmission in the anterior cingulate cortex of viscerally hypersensitive rats. American Journal of Physiology. Gastrointestinal and Liver Physiology, 294(4), G918-G927.
    • (2008) American Journal of Physiology. Gastrointestinal and Liver Physiology , vol.294 , Issue.4
    • Wu, X.1    Gao, J.2    Yan, J.3    Fan, J.4    Owyang, C.5    Li, Y.6
  • 46
    • 79958129600 scopus 로고    scopus 로고
    • Validation of an accelerated solvent extraction liquid chromatography-tandem mass spectrometry method for Pacific ciguatoxin-1 in fish flesh and comparison with the mouse neuroblastoma assay
    • 21505950 10.1007/s00216-011-4977-4 1:CAS:528:DC%2BC3MXkvVynsrw%3D
    • Wu, J. J.; Mak, Y. L.; Murphy, M. B.; Lam, J. C.; Chan, W. H.; Wang, M.; et al. (2011). Validation of an accelerated solvent extraction liquid chromatography-tandem mass spectrometry method for Pacific ciguatoxin-1 in fish flesh and comparison with the mouse neuroblastoma assay. Analytical and Bioanalytical Chemistry, 400, 3165-3175.
    • (2011) Analytical and Bioanalytical Chemistry , vol.400 , pp. 3165-3175
    • Wu, J.J.1    Mak, Y.L.2    Murphy, M.B.3    Lam, J.C.4    Chan, W.H.5    Wang, M.6    Chan, L.L.7    Lam, P.K.8
  • 47
    • 84155194952 scopus 로고    scopus 로고
    • Glutamatergic activation of anterior cingulate cortex mediates the affective component of visceral pain memory in rats
    • 22107830 10.1016/j.nlm.2011.11.003 1:CAS:528:DC%2BC38XhtlWqtA%3D%3D
    • Yan, N.; Cao, B.; Xu, J.; Hao, C.; Zhang, X.; & Li, Y. (2012). Glutamatergic activation of anterior cingulate cortex mediates the affective component of visceral pain memory in rats. Neurobiology of Learning and Memory, 97, 156-164.
    • (2012) Neurobiology of Learning and Memory , vol.97 , pp. 156-164
    • Yan, N.1    Cao, B.2    Xu, J.3    Hao, C.4    Zhang, X.5    Li, Y.6
  • 48
    • 33751543451 scopus 로고    scopus 로고
    • Intracortical circuits in rat anterior cingulate cortex are activated by nociceptive inputs mediated by medial thalamus
    • 16956990 10.1152/jn.00623.2006
    • Yang, J. W.; Shih, H. C.; & Shyu, B. C. (2006). Intracortical circuits in rat anterior cingulate cortex are activated by nociceptive inputs mediated by medial thalamus. Journal of Neurophysiology, 96, 3409-3422.
    • (2006) Journal of Neurophysiology , vol.96 , pp. 3409-3422
    • Yang, J.W.1    Shih, H.C.2    Shyu, B.C.3
  • 49
    • 0024504982 scopus 로고
    • Development of saxitoxin-sensitive and insensitive sodium channels in cultured neonatal rat astrocytes
    • 2538579 1:STN:280:DyaL1M7nslClug%3D%3D
    • Yarowsky, P. J.; & Krueger, B. K. (1989). Development of saxitoxin-sensitive and insensitive sodium channels in cultured neonatal rat astrocytes. Journal of Neuroscience, 9, 1055-1061.
    • (1989) Journal of Neuroscience , vol.9 , pp. 1055-1061
    • Yarowsky, P.J.1    Krueger, B.K.2


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