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Volumn , Issue , 2008, Pages 481-490

Compound Properties and Drug Quality

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EID: 84877738654     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-374194-3.00022-6     Document Type: Chapter
Times cited : (3)

References (16)
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    • Identification and evaluation of molecular properties related to preclinical optimization and clinical fate
    • Blake J.F. Identification and evaluation of molecular properties related to preclinical optimization and clinical fate. Med. Chem. 2005, 1:649-655.
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    • The influence of target family and functional activity on the physicochemical properties of pre-clinical compounds
    • Morphy R. The influence of target family and functional activity on the physicochemical properties of pre-clinical compounds. J. Med. Chem. 2006, 49:2969-2978.
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    • Morphy, R.1
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    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski C.A., Lombardo F., Dominy B.W., Feeney P.J. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. 2001, 46:3-26.
    • (2001) Adv. Drug Deliv. Rev. , vol.46 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 6
    • 33847381100 scopus 로고    scopus 로고
    • A decade of fragment-based drug design: strategic advances and lessons learned
    • Hajduk P.J., Greer J. A decade of fragment-based drug design: strategic advances and lessons learned. Nat. Rev. Drug Discov. 2007, 6(3):211-219.
    • (2007) Nat. Rev. Drug Discov. , vol.6 , Issue.3 , pp. 211-219
    • Hajduk, P.J.1    Greer, J.2
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    • 34548039925 scopus 로고    scopus 로고
    • Solubility of sparingly-soluble ionizable drugs
    • Avdeef A. Solubility of sparingly-soluble ionizable drugs. Adv. Drug Deliv. Rev. 2007, 59(7):568-590.
    • (2007) Adv. Drug Deliv. Rev. , vol.59 , Issue.7 , pp. 568-590
    • Avdeef, A.1
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    • 1042287180 scopus 로고    scopus 로고
    • Drug polymorphism and dosage form design: a practical perspective
    • Singhal D., Curatolo W. Drug polymorphism and dosage form design: a practical perspective. Adv. Drug Deliv. Rev. 2004, 56(3):335-347.
    • (2004) Adv. Drug Deliv. Rev. , vol.56 , Issue.3 , pp. 335-347
    • Singhal, D.1    Curatolo, W.2
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    • 0036821028 scopus 로고    scopus 로고
    • The consequences of translational and rotational entropy lost by small molecules on binding to proteins
    • Murray C.W., Verdonk M.L. The consequences of translational and rotational entropy lost by small molecules on binding to proteins. J. Comput.-Aided Mol. Des. 2002, 16(10):741-753.
    • (2002) J. Comput.-Aided Mol. Des. , vol.16 , Issue.10 , pp. 741-753
    • Murray, C.W.1    Verdonk, M.L.2
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    • Drug-like properties: guiding principles for design - or chemical prejudice?
    • Leeson P.D., Davis A.M., Steele J. Drug-like properties: guiding principles for design - or chemical prejudice?. Drug Discov. Today Tech. 2004, 1(3):189-195.
    • (2004) Drug Discov. Today Tech. , vol.1 , Issue.3 , pp. 189-195
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  • 14
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    • Ligand efficiency: a useful metric for lead selection
    • Hopkins A.L., Groom C.R., Alex A. Ligand efficiency: a useful metric for lead selection. Drug Discov. Today 2004, 9(10):430-431.
    • (2004) Drug Discov. Today , vol.9 , Issue.10 , pp. 430-431
    • Hopkins, A.L.1    Groom, C.R.2    Alex, A.3
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.