Effects of (-)-gallocatechin-3-gallate on tetrodotoxin-resistant voltage-gated sodium channels in rat dorsal root ganglion neurons

International Journal of Molecular Sciences

Volumn 14, Issue 5, 2013, Pages 9779-9789

  Zhang, Yan ^a   Jia, Yan Yan ^a   Guo, Jin Lei ^a   Liu, Pei Qing ^a   Jiang, Jian Min ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

( ) gallocatechin 3 gallate; Catechins; Dorsal root ganglion; Na+ channel; Tetrodotoxin resistant

Indexed keywords

CATECHIN; GALLOCATECHIN 3 GALLATE; SODIUM CHANNEL NAV1.8; SODIUM CHANNEL NAV1.9; TETRODOTOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL; GALLOCATECHIN GALLATE; SODIUM; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; DRUG MECHANISM; ELECTRIC POTENTIAL; HYPERPOLARIZATION; NEWBORN; NONHUMAN; RAT; SODIUM CURRENT; SPINAL CORD NERVE CELL; SPINAL GANGLION; ANALOGS AND DERIVATIVES; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; DRUG RESISTANCE; METABOLISM; PATCH CLAMP TECHNIQUE; SPRAGUE DAWLEY RAT;

ANIMALS; CATECHIN; CELLS, CULTURED; DRUG RESISTANCE; GANGLIA, SPINAL; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; SODIUM; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TETRODOTOXIN;

EID: 84877722928     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms14059779     Document Type: Article

References (21)

1. Kaur, S.; Anurag, A.; Tirkey, N.; Chopra, K. Reversal of LPS-induced central and peripheral hyperalgesia by green tea extract. Phytother. Res. 2005, 19, 39-43.
2. Renno, W.M.; Saleh, F.; Klepacek, I.; Al-Khaledi, G.; Ismael, H.; Asfar, S. Green tea pain modulating effect in sciatic nerve chronic constriction injury rat model. Nutr. Neurosci. 2006, 9, 41-47.
3. Choi, J.I.; Kim, W.M.; Lee, H.G.; Kim, Y.O.; Yoon, M.H. Role of neuronal nitric oxide synthase in the antiallodynic effects of intrathecal EGCG in a neuropathic pain rat model. Neurosci. Lett. 2012, 510, 53-57.
4. Kuang, X.; Huang, Y.; Gu, H.F.; Zu, X.Y.; Zou, W.Y.; Song, Z.B.; Guo, Q.L. Effects of intrathecal epigallocatechin gallate, an inhibitor of Toll-like receptor 4, on chronic neuropathic pain in rats. Eur. J. Pharmacol. 2012, 676, 51-56.
5. 2+ and nitric oxide release. Eur. J. Pharmacol. 2006, 552, 123-130.
6. Ikeda, I.; Kobayashi, M.; Hamada, T.; Tsuda, K.; Goto, H.; Imaizumi, K.; Nozawa, A.; Sugimoto, A.; Kakuda, T. Heat-epimerized tea catechins rich in gallocatechin gallate and catechin gallate are more effective to inhibit cholesterol absorption than tea catechins rich in epigallocatechin gallate and epicatechin gallate. J. Agric. Food Chem. 2003, 51, 7303-7307.
7. Peng, L.; Khan, N.; Afaq, F.; Ye, C.; Mukhtar, H. In vitro and in vivo effects of water extract of white cocoa tea (Camellia ptilophylla) against human prostate cancer. Pharm. Res. 2010, 27, 1128-1137.
8. Waxman, S.G.; Cummins, T.R.; Dib-Hajj, S.; Fjell, J.; Black, J.A. Sodium channels, excitability of primary sensory neurons, and the molecular basis of pain. Muscle Nerve 1999, 22, 1177-1187.
9. Leo, S.; D'Hooge, R.; Meert, T. Exploring the role of nociceptor-specific sodium channels in pain transmission using Nav1.8 and Nav1.9 knockout mice. Behav. Brain Res. 2010, 208, 149-157.
10. Kim, T.H.; Lim, J.M.; Kim, S.S.; Kim, J.; Park, M.; Song, J.H. Effects of (-)-epigallocatechin-3-gallate on Na(+) currents in rat dorsal root ganglion neurons. Eur. J. Pharmacol. 2009, 604, 20-26.
11. Deng, H.M.; Yin, S.T.; Yan, D.; Tang, M.L.; Li, C.C.; Chen, J.T.; Wang, M.; Ruan, D.Y. Effects of EGCG on voltage-gated sodium channels in primary cultures of rat hippocampal CA1 neurons. Toxicology 2008, 252, 1-8.
12. Weiser, T.; Wilson, N. Inhibition of tetrodotoxin (TTX)-resistant and TTX-sensitive neuronal Na(+) channels by the secretolytic ambroxol. Mol. Pharmacol. 2002, 62, 433-438.
13. + channels and vanilloid VR1 receptors. Eur. J. Pharmacol. 2004, 485, 11-20.
14. Kelemen, K.; Kiesecker, C.; Zitron, E.; Bauer, A.; Scholz, E.; Bloehs, R.; Thomas, D.; Greten, J.; Remppis, A.; Schoels, W. et al. Green tea flavonoid epigallocatechin-3-gallate (EGCG) inhibits cardiac hERG potassium channels. Biochem. Biophys. Res. Commun. 2007, 364, 429-435.
15. Kang, J.; Cheng, H.; Ji, J.; Incardona, J.; Rampe, D. In vitro electrocardiographic and cardiac ion channel effects of (-)-epigallocatechin-3-gallate, the main catechin of green tea. J. Pharmacol. Exp. Ther. 2010, 334, 619-626.
16. Hirai, M.; Hotta, Y.; Ishikawa, N.; Wakida, Y.; Fukuzawa, Y.; Isobe, F.; Nakano, A.; Chiba, T.; Kawamura, N. Protective effects of EGCg or GCg, a green tea catechin epimer, against postischemic myocardial dysfunction in guinea-pig hearts. Life Sci. 2007, 80, 1020-1032.
17. Lee, S.M.; Kim, C.W.; Kim, J.K.; Shin, H.J.; Baik, J.H. GCG-rich tea catechins are effective in lowering cholesterol and triglyceride concentrations in hyperlipidemic rats. Lipids 2008, 43, 419-429.
18. Masukawa, Y.; Matsui, Y.; Shimizu, N.; Kondou, N.; Endou, H.; Kuzukawa, M.; Hase, T. Determination of green tea catechins in human plasma using liquid chromatography-electrospray ionization mass spectrometry. J. Chromatogr. B 2006, 834, 26-34.
19. Kotani, A.; Miyashita, N.; Kusu, F. Determination of catechins in human plasma after commercial canned green tea ingestion by high-performance liquid chromatography with electrochemical detection using a microbore column. J. Chromatogr. B 2003, 788, 269-275.
20. Chow, H.H.; Hakim, I.A.; Vining, D.R.; Crowell, J.A.; Ranger-Moore, J.; Chew, W.M.; Celaya, C.A.; Rodney, S.R.; Hara, Y.; Alberts, D.S. Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individuals. Clin. Cancer Res. 2005, 11, 4627-4633.
21. Xu, J.Z.; Yeung, S.Y.; Chang, Q.; Huang, Y.; Chen, Z.Y. Comparison of antioxidant activity and bioavailability of tea epicatechins with their epimers. Br. J. Nutr. 2004, 91, 873-881.