Human antibody fragments specific for Bothrops jararacussu venom reduce the toxicity of other Bothrops sp. venoms

Journal of Immunotoxicology

Volumn 10, Issue 2, 2013, Pages 160-168

  Roncolato, Eduardo Crosara ^a   Pucca, Manuela Berto ^a   Funayama, Jaqueline Carlos ^b   Bertolini, Thaís Barboza ^a   Campos, Lucas Benício ^a   Barbosa, José Elpidio ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Sul de Minas Federal Institute of Education Science and Technology   (Brazil)

Author keywords

Antivenom; Bothrops sp.; Phage display; Phospholipase A2; ScFv

Indexed keywords

BOTHROPS JARARACUSSU VENOM; MONOCLONAL ANTIBODY; PHOSPHOLIPASE A2; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; SNAKE VENOM; SNAKE VENOM ANTISERUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY LIBRARY; ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ARTICLE; BOTHROPS; BOTHROPS JARARACA; BOTHROPS JARARACUSSU; BOTHROPS MOOJENI; BOTHROPS NEUWIEDI; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HEMOLYSIS; LD 50; LETHALITY; MOLECULAR CLONING; MOUSE; MYOTOXICITY; NONHUMAN; PRIORITY JOURNAL; SURVIVAL; TOXICITY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIVENINS; BOTHROPS; CELL SURFACE DISPLAY TECHNIQUES; CREATINE KINASE; CROTALID VENOMS; FEMALE; HEMOLYTIC PLAQUE TECHNIQUE; HUMANS; MICE; PHOSPHOLIPASES A2; SINGLE-CHAIN ANTIBODIES; SPECIES SPECIFICITY; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 84877717092     PISSN: 1547691X     EISSN: None     Source Type: Journal    
DOI: 10.3109/1547691X.2012.703253     Document Type: Article

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