Substrate stiffness affects sarcomere and costamere structure and electrophysiological function of isolated adult cardiomyocytes

Cardiovascular Pathology

Volumn 22, Issue 3, 2013, Pages 219-227

  Galie, Peter A ^a   Khalid, Nashmia ^a   Carnahan, Kelly E ^a   Westfall, Margaret V ^b   Stegemann, Jan P ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Adult cardiomyocyte; Costamere; Fibrosis; Sarcomere; Substrate stiffness

Indexed keywords

ALPHA ACTININ; ALPHA7 INTEGRIN; BETA1 INTEGRIN; CALCIUM ION; CALYCULIN A; DIMETICONE; VINCULIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL MODEL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL FUNCTION; CELL STRUCTURE; COSTAMERE; EXTRACELLULAR MATRIX; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBROSIS; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIGIDITY; SARCOMERE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CELLS, CULTURED; COSTAMERES; EXTRACELLULAR MATRIX; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOBLOTTING; MECHANICAL PHENOMENA; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SARCOMERES;

EID: 84877697758     PISSN: 10548807     EISSN: 18791336     Source Type: Journal    
DOI: 10.1016/j.carpath.2012.10.003     Document Type: Article

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