-
1
-
-
33750705653
-
A century of Alzheimer's disease
-
Goedert M, Spillantini MG, (2006) A century of Alzheimer's disease. Science 314: 777-781.
-
(2006)
Science
, vol.314
, pp. 777-781
-
-
Goedert, M.1
Spillantini, M.G.2
-
2
-
-
0035964312
-
Immune hyporesponsiveness to amyloid beta-peptide in amyloid precursor protein transgenic mice: implications for the pathogenesis and treatment of Alzheimer's disease
-
Monsonego A, Maron R, Zota V, Selkoe DJ, Weiner HL, (2001) Immune hyporesponsiveness to amyloid beta-peptide in amyloid precursor protein transgenic mice: implications for the pathogenesis and treatment of Alzheimer's disease. Proc Natl Acad Sci U S A 98: 10273-10278.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10273-10278
-
-
Monsonego, A.1
Maron, R.2
Zota, V.3
Selkoe, D.J.4
Weiner, H.L.5
-
3
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
-
Hardy J, Selkoe DJ, (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297: 353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
4
-
-
78650678688
-
Decreased clearance of CNS beta-amyloid in Alzheimer's disease
-
Mawuenyega KG, Sigurdson W, Ovod V, Munsell L, Kasten T, et al. (2010) Decreased clearance of CNS beta-amyloid in Alzheimer's disease. Science 330: 1774.
-
(2010)
Science
, vol.330
, pp. 1774
-
-
Mawuenyega, K.G.1
Sigurdson, W.2
Ovod, V.3
Munsell, L.4
Kasten, T.5
-
5
-
-
0019972810
-
The cholinergic hypothesis of geriatric memory dysfunction
-
Bartus RT, Dean RL 3rd, Beer B, Lippa AS (1982) The cholinergic hypothesis of geriatric memory dysfunction. Science 217: 408-414.
-
(1982)
Science
, vol.217
, pp. 408-414
-
-
Bartus, R.T.1
Dean III, R.L.2
Beer, B.3
Lippa, A.S.4
-
7
-
-
33745402341
-
Acetylcholinesterase inhibitors for Alzheimer's disease: anti-inflammatories in acetylcholine clothing!
-
Tabet N, (2006) Acetylcholinesterase inhibitors for Alzheimer's disease: anti-inflammatories in acetylcholine clothing! Age Ageing. 35: 336-338.
-
(2006)
Age Ageing
, vol.35
, pp. 336-338
-
-
Tabet, N.1
-
8
-
-
0034635589
-
No interaction of memantine with acetylcholinesterase inhibitors approved for clinical use
-
Wenk GL, Quack G, Moebius HJ, Danysz W, (2000) No interaction of memantine with acetylcholinesterase inhibitors approved for clinical use. Life Sci 66: 1079-1083.
-
(2000)
Life Sci
, vol.66
, pp. 1079-1083
-
-
Wenk, G.L.1
Quack, G.2
Moebius, H.J.3
Danysz, W.4
-
9
-
-
84871220525
-
Benzylphenethylamine alkaloids from the bulbs and flowers of Lycoris radiata
-
Wang H, Wang YH, Zhao FW, Huang QQ, Xu JJ, et al. (2011) Benzylphenethylamine alkaloids from the bulbs and flowers of Lycoris radiata. Chin Herbal Mediciens 3: 60-63.
-
(2011)
Chin Herbal Mediciens
, vol.3
, pp. 60-63
-
-
Wang, H.1
Wang, Y.H.2
Zhao, F.W.3
Huang, Q.Q.4
Xu, J.J.5
-
10
-
-
84891489966
-
Supercritical CO2 extraction technology of lycorenine in L. radiata
-
Geng ZF, Lv HS, Zhang MH, (2008) Supercritical CO2 extraction technology of lycorenine in L. radiata. Chin Tradit Herb Drugs 39: 543-546.
-
(2008)
Chin Tradit Herb Drugs
, vol.39
, pp. 543-546
-
-
Geng, Z.F.1
Lv, H.S.2
Zhang, M.H.3
-
11
-
-
66949112200
-
Two new amaryllidaceae alkaloids from the bulbs of Lycoris radiata
-
Wang L, Zhang XQ, Yin ZQ, Wang Y, Ye WC, (2009) Two new amaryllidaceae alkaloids from the bulbs of Lycoris radiata. Chem Pharm Bull (Tokyo) 57: 610-611.
-
(2009)
Chem Pharm Bull (Tokyo)
, vol.57
, pp. 610-611
-
-
Wang, L.1
Zhang, X.Q.2
Yin, Z.Q.3
Wang, Y.4
Ye, W.C.5
-
12
-
-
0043204252
-
Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function
-
Howes MJ, Houghton PJ, (2003) Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function. Pharmacol Biochem Behav 75: 513-527.
-
(2003)
Pharmacol Biochem Behav
, vol.75
, pp. 513-527
-
-
Howes, M.J.1
Houghton, P.J.2
-
13
-
-
4444232329
-
Galantamine and nicotine have a synergistic effect on inhibition of microglial activation induced by HIV-1 gp120
-
Giunta B, Ehrhart J, Townsend K, Sun N, Vendrame M, et al. (2004) Galantamine and nicotine have a synergistic effect on inhibition of microglial activation induced by HIV-1 gp120. Brain Res Bull 64: 165-170.
-
(2004)
Brain Res Bull
, vol.64
, pp. 165-170
-
-
Giunta, B.1
Ehrhart, J.2
Townsend, K.3
Sun, N.4
Vendrame, M.5
-
14
-
-
0037461768
-
Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation
-
Wang H, Yu M, Ochani M, Amella CA, Tanovic M, et al. (2003) Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 421: 384-388.
-
(2003)
Nature
, vol.421
, pp. 384-388
-
-
Wang, H.1
Yu, M.2
Ochani, M.3
Amella, C.A.4
Tanovic, M.5
-
15
-
-
14844322281
-
Acetylcholinesterase inhibitors effects on oncostatin-M, interleukin-1 beta and interleukin-6 release from lymphocytes of Alzheimer's disease patients
-
Reale M, Iarlori C, Gambi F, Lucci I, Salvatore M, et al. (2005) Acetylcholinesterase inhibitors effects on oncostatin-M, interleukin-1 beta and interleukin-6 release from lymphocytes of Alzheimer's disease patients. Exp Gerontol 40: 165-171.
-
(2005)
Exp Gerontol
, vol.40
, pp. 165-171
-
-
Reale, M.1
Iarlori, C.2
Gambi, F.3
Lucci, I.4
Salvatore, M.5
-
16
-
-
0342409367
-
Huperzine B, a novel acetylcholinesterase inhibitor, attenuates hydrogen peroxide induced injury in PC12 cells
-
Zhang HY, Tang XC, (2000) Huperzine B, a novel acetylcholinesterase inhibitor, attenuates hydrogen peroxide induced injury in PC12 cells. Neurosci Lett 292: 41-44.
-
(2000)
Neurosci Lett
, vol.292
, pp. 41-44
-
-
Zhang, H.Y.1
Tang, X.C.2
-
17
-
-
0037202279
-
Tacrine attenuates hydrogen peroxide-induced apoptosis by regulating expression of apoptosis-related genes in rat PC12 cells
-
Wang R, Zhou J, Tang XC, (2002) Tacrine attenuates hydrogen peroxide-induced apoptosis by regulating expression of apoptosis-related genes in rat PC12 cells. Brain Res Mol Brain Res 107: 1-8.
-
(2002)
Brain Res Mol Brain Res
, vol.107
, pp. 1-8
-
-
Wang, R.1
Zhou, J.2
Tang, X.C.3
-
18
-
-
0034284410
-
Huperzine A and tacrine attenuate beta-amyloid peptide-induced oxidative injury
-
Xiao XQ, Wang R, Tang XC, (2000) Huperzine A and tacrine attenuate beta-amyloid peptide-induced oxidative injury. J Neurosci Res 61: 564-569.
-
(2000)
J Neurosci Res
, vol.61
, pp. 564-569
-
-
Xiao, X.Q.1
Wang, R.2
Tang, X.C.3
-
19
-
-
0028981288
-
Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans
-
Link CD, (1995) Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans. Proc Natl Acad Sci U S A 92: 9368-9372.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 9368-9372
-
-
Link, C.D.1
-
20
-
-
33751397131
-
C. elegans models of age-associated neurodegenerative diseases: lessons from transgenic worm models of Alzheimer's disease
-
Link CD, (2006) C. elegans models of age-associated neurodegenerative diseases: lessons from transgenic worm models of Alzheimer's disease. Exp Gerontol 41: 1007-1013.
-
(2006)
Exp Gerontol
, vol.41
, pp. 1007-1013
-
-
Link, C.D.1
-
21
-
-
26444582959
-
Soy isoflavone glycitein protects against beta amyloid-induced toxicity and oxidative stress in transgenic Caenorhabditis elegans
-
Gutierrez-Zepeda A, Santell R, Wu Z, Brown M, Wu Y, et al. (2005) Soy isoflavone glycitein protects against beta amyloid-induced toxicity and oxidative stress in transgenic Caenorhabditis elegans. BMC Neurosci 6: 54.
-
(2005)
BMC Neurosci
, vol.6
, pp. 54
-
-
Gutierrez-Zepeda, A.1
Santell, R.2
Wu, Z.3
Brown, M.4
Wu, Y.5
-
22
-
-
33845613251
-
Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans
-
Wu Y, Wu Z, Butko P, Christen Y, Lambert MP, et al. (2006) Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans. J Neurosci 26: 13102-13113.
-
(2006)
J Neurosci
, vol.26
, pp. 13102-13113
-
-
Wu, Y.1
Wu, Z.2
Butko, P.3
Christen, Y.4
Lambert, M.P.5
-
23
-
-
67349229369
-
Reserpine ameliorates Abeta toxicity in the Alzheimer's disease model in Caenorhabditis elegans
-
Arya U, Dwivedi H, Subramaniam JR, (2009) Reserpine ameliorates Abeta toxicity in the Alzheimer's disease model in Caenorhabditis elegans. Exp Gerontol 44: 462-466.
-
(2009)
Exp Gerontol
, vol.44
, pp. 462-466
-
-
Arya, U.1
Dwivedi, H.2
Subramaniam, J.R.3
-
24
-
-
1842431888
-
Acetylcholinesterase enzyme inhibitory effects of amaryllidaceae alkaloids
-
Elgorashi EE, Stafford GI, Van Staden J, (2004) Acetylcholinesterase enzyme inhibitory effects of amaryllidaceae alkaloids. Planta Med 70: 260-262.
-
(2004)
Planta Med
, vol.70
, pp. 260-262
-
-
Elgorashi, E.E.1
Stafford, G.I.2
Van Staden, J.3
-
25
-
-
80055117409
-
Assaying beta-amyloid toxicity using a transgenic C. elegans model
-
doi: 10.3791/2252
-
Dostal V, Link CD (2010) Assaying beta-amyloid toxicity using a transgenic C. elegans model. JoVe. doi: 10.3791/2252.
-
(2010)
JoVe
-
-
Dostal, V.1
Link, C.D.2
-
26
-
-
12244281810
-
Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model
-
Drake J, Link CD, Butterfield DA, (2003) Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model. Neurobiol Aging 24: 415-420.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 415-420
-
-
Drake, J.1
Link, C.D.2
Butterfield, D.A.3
-
28
-
-
0037405291
-
Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model
-
Link CD, Taft A, Kapulkin V, Duke K, Kim S, et al. (2003) Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model. Neurobiol Aging 24: 397-413.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 397-413
-
-
Link, C.D.1
Taft, A.2
Kapulkin, V.3
Duke, K.4
Kim, S.5
-
29
-
-
0034813088
-
Acetylcholinesterase genes in the nematode Caenorhabditis elegans
-
Combes D, Fedon Y, Toutant JP, Arpagaus M, (2001) Acetylcholinesterase genes in the nematode Caenorhabditis elegans. Int Rev Cytol 209: 207-239.
-
(2001)
Int Rev Cytol
, vol.209
, pp. 207-239
-
-
Combes, D.1
Fedon, Y.2
Toutant, J.P.3
Arpagaus, M.4
-
30
-
-
0033618267
-
Structure and promoter activity of the 5′ flanking region of ace-1, the gene encoding acetylcholinesterase of class A in Caenorhabditis elegans
-
Culetto E, Combes D, Fedon Y, Roig A, Toutant JP, et al. (1999) Structure and promoter activity of the 5′ flanking region of ace-1, the gene encoding acetylcholinesterase of class A in Caenorhabditis elegans. J Mol Biol 290: 951-966.
-
(1999)
J Mol Biol
, vol.290
, pp. 951-966
-
-
Culetto, E.1
Combes, D.2
Fedon, Y.3
Roig, A.4
Toutant, J.P.5
-
31
-
-
0041879942
-
Multiple ace genes encoding acetylcholinesterases of Caenorhabditis elegans have distinct tissue expression
-
Combes D, Fedon Y, Toutant JP, Arpagaus M, (2003) Multiple ace genes encoding acetylcholinesterases of Caenorhabditis elegans have distinct tissue expression. Eur J Neurosci 18: 497-512.
-
(2003)
Eur J Neurosci
, vol.18
, pp. 497-512
-
-
Combes, D.1
Fedon, Y.2
Toutant, J.P.3
Arpagaus, M.4
-
32
-
-
28744443582
-
Nematode acetylcholinesterases are encoded by multiple genes and perform non-overlapping functions
-
Selkirk ME, Lazari O, Hussein AS, Matthews JB, (2005) Nematode acetylcholinesterases are encoded by multiple genes and perform non-overlapping functions. Chem Biol Interact 157-158: 263-268.
-
(2005)
Chem Biol Interact
, vol.157-158
, pp. 263-268
-
-
Selkirk, M.E.1
Lazari, O.2
Hussein, A.S.3
Matthews, J.B.4
-
33
-
-
0029033167
-
Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation
-
Barger SW, Horster D, Furukawa K, Goodman Y, Krieglstein J, et al. (1995) Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation. Proc Natl Acad Sci U S A 92: 9328-9332.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 9328-9332
-
-
Barger, S.W.1
Horster, D.2
Furukawa, K.3
Goodman, Y.4
Krieglstein, J.5
-
34
-
-
67651157036
-
Biological evaluation of structurally diverse amaryllidaceae alkaloids and their synthetic derivatives: discovery of novel leads for anticancer drug design
-
Evidente A, Kireev AS, Jenkins AR, Romero AE, Steelant WF, et al. (2009) Biological evaluation of structurally diverse amaryllidaceae alkaloids and their synthetic derivatives: discovery of novel leads for anticancer drug design. Planta Med 75: 501-507.
-
(2009)
Planta Med
, vol.75
, pp. 501-507
-
-
Evidente, A.1
Kireev, A.S.2
Jenkins, A.R.3
Romero, A.E.4
Steelant, W.F.5
-
35
-
-
67651155818
-
Anticancer evaluation of structurally diverse Amaryllidaceae alkaloids and their synthetic derivatives
-
Evidente A, Komienko A, (2009) Anticancer evaluation of structurally diverse Amaryllidaceae alkaloids and their synthetic derivatives. Phytochem Rev 8: 449-459.
-
(2009)
Phytochem Rev
, vol.8
, pp. 449-459
-
-
Evidente, A.1
Komienko, A.2
-
37
-
-
33845325215
-
Preparation of secolycorines against acetylcholinesterase
-
Lee SS, Venkatesham U, Rao CP, Lam SH, Lin JH, (2007) Preparation of secolycorines against acetylcholinesterase. Bioorg Med Chem 15: 1034-1043.
-
(2007)
Bioorg Med Chem
, vol.15
, pp. 1034-1043
-
-
Lee, S.S.1
Venkatesham, U.2
Rao, C.P.3
Lam, S.H.4
Lin, J.H.5
|