A complicated liaison: IL-33 and IL-33R in arthritis pathogenesis

Arthritis Research and Therapy

Volumn 15, Issue 3, 2013, Pages

  Kamradt, Thomas ^a   Drube, Sebastian ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 33; INTERLEUKIN 33 RECEPTOR; STEM CELL FACTOR RECEPTOR; UNCLASSIFIED DRUG; INTERLEUKIN DERIVATIVE;

ARTHRITIS; DNA POLYMORPHISM; EDITORIAL; HUMAN; KNOCKOUT MOUSE; MACROPHAGE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; EXPERIMENTAL ARTHRITIS; IMMUNOLOGY; RHEUMATOID ARTHRITIS;

ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; INTERLEUKINS;

EID: 84877616048     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar4209     Document Type: Editorial

References (14)

1. Martin P, Talabot-Ayer D, Seemayer CA, Vigne S, Lamacchia C, Rodriguez E, Finckh A, Smith DE, Gabay C, Palmer G. Disease severity in K/BxN serum transfer-induced arthritis is not affected by IL-33 deficiency. Arthritis Res Ther 2013, 15:R13. 10.1186/ar4143, 23324173.
2. Smith DE. The biological paths of IL-1 family members IL-18 and IL-33. J Leukoc Biol 2011, 89:383-392. 10.1189/jlb.0810470, 20952658.
3. Oboki K, Ohno T, Kajiwara N, Saito H, Nakae S. IL-33 and IL-33 receptors in host defense and diseases. Allergol Int 2010, 59:143-160. 10.2332/allergolint.10-RAI-0186, 20414050.
4. Meisel C, Bonhagen K, Löhning M, Coyle AC, Guttierez-Ramos JC, Radbruch A, Kamradt T. Regulation and function of T1/ST2-expression on CD4+ T cells: induction of type 2 cytokine production by T1/ST2-crosslinking. J Immunol 2001, 166:3143-3150.
5. Palmer G, Talabot-Ayer D, Lamacchia C, Toy D, Seemayer CA, Viatte S, Finckh A, Smith DE, Gabay C. Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis. Arthritis Rheum 2009, 60:738-749. 10.1002/art.24305, 19248109.
6. Xu D, Jiang HR, Kewin P, Li Y, Mu R, Fraser AR, Pitman N, Kurowska-Stolarska M, McKenzie AN, McInnes IB, Liew FY. IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proc Natl Acad Sci USA 2008, 105:10913-10918. 10.1073/pnas.0801898105, 2491487, 18667700.
7. Zaiss MM, Kurowska-Stolarska M, Böhm C, Gary R, Scholtysek C, Stolarski B, Reilly J, Kerr S, Millar NL, Kamradt T, McInnes IB, Fallon PG, David JP, Liew FY, Schett G. IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-alpha-mediated bone loss. J Immunol 2011, 186:6097-6105. 10.4049/jimmunol.1003487, 21515798.
8. Xu D, Jiang HR, Li Y, Pushparaj PN, Kurowska-Stolarska M, Leung BP, Mu R, Tay HK, McKenzie AN, McInnes IB, Melendez AJ, Liew FY. IL-33 exacerbates autoantibody-induced arthritis. J Immunol 2010, 184:2620-2626. 10.4049/jimmunol.0902685, 20139274.
9. Anthony RM, Kobayashi T, Wermeling F, Ravetch JV. Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway. Nature 2011, 475:110-113. 10.1038/nature10134, 21685887.
10. Holmdahl R, Malissen B. The need for littermate controls. Eur J Immunol 2012, 42:45-47. 10.1002/eji.201142048, 22213045.
11. Brint EK, Xu D, Liu H, Dunne A, McKenzie AN, O'Neill LA, Liew FY. ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat Immunol 2004, 5:373-379. 10.1038/ni1050, 15004556.
12. Kamradt T, Schubert D. The role and clinical implications of G6PI in experimental models of rheumatoid arthritis. Arthritis Res 2005, 7:20-28.
13. Gutcher I, Urich E, Wolter K, Prinz M, Becher B. Interleukin 18-independent engagement of interleukin 18 receptor-alpha is required for autoimmune inflammation. Nat Immunol 2006, 7:946-953. 10.1038/ni1377, 16906165.
14. Drube S, Heink S, Walter S, Löhn T, Grusser M, Gerbaulet A, Berod L, Schons J, Dudeck A, Freitag J, Grotha S, Reich D, Rudeschko O, Norgauer J, Hartmann K, Roers A, Kamradt T. The receptor tyrosine kinase c-Kit controls IL-33 receptor signaling in mast cells. Blood 2010, 115:3899-3906. 10.1182/blood-2009-10-247411, 20200353.