Small airway obstruction in COPD: New insights based on micro-CT imaging and MRI imaging

Chest

Volumn 143, Issue 5, 2013, Pages 1436-1443

  Hogg, James C ^a   McDonough, John E ^a,b   Suzuki, Masaru ^a,c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AIRBORNE PARTICLE; AIRWAY OBSTRUCTION; AIRWAY REMODELING; AIRWAY RESISTANCE; ARTICLE; BRONCHIOLE; CELL INFILTRATION; CHRONIC INFLAMMATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; DISEASE COURSE; DISEASE SEVERITY; FORCED EXPIRATORY VOLUME; HISTOPATHOLOGY; HUMAN; IMAGE ANALYSIS; IMMUNOCOMPETENT CELL; LUNG DIFFUSION; LUNG EMPHYSEMA; MICRO-COMPUTED TOMOGRAPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; TIDAL VOLUME; TISSUE INJURY; TISSUE REPAIR; TOTAL LUNG CAPACITY;

EID: 84877611560     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.12-1766     Document Type: Article

References (41)

1. Rabe KF, Hurd S, Anzueto A, et al Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2007;176(6):532-555. (Pubitemid 47403272)
2. Hogg JC, Chu F, Utokaparch S, et al. The nature of smallairway obstruction in chronic obstructive pulmonary disease. N Engl J Med. 2004;350(26):2645-2653. (Pubitemid 38787999)
3. Kumar V, Abbas A, Fausto N. Tissue renewal and repair: regeneration, healing and fibrosis. In: Robbins & Cotran Pathologic Basis of Disease. 7th ed. Elsevier Saunders; 2005:87-118.
4. Reid L. Measurement of the bronchial mucous gland layer: a diagnostic yardstick in chronic bronchitis. Thorax. 1960;15:132-141.
5. Mullen JB, Wright JL, Wiggs BR, Pare PD, Hogg JC. Reassessment of inflammation of airways in chronic bronchitis. Br Med J (Clin Res Ed). 1985;291(6504):1235-1239. (Pubitemid 16223211)
6. Saetta M, Di Stefano A, Maestrelli P, et al. Activated T-lymphocytes and macrophages in bronchial mucosa of subjects with chronic bronchitis. Am Rev Respir Dis. 1993;147(2):301-306. (Pubitemid 23044899)
7. Hogg JC, Macklem PT, Thurlbeck WM. Site and nature of airway obstruction in chronic obstructive lung disease. N Engl J Med. 1968;278(25):1355-1360.
8. Miller WS. The Lung. Springfield, IL: C. C. Thomas; 1947:222.
9. McDonough JE, Yuan R, Suzuki M, et al. Small-airway obstruction and emphysema in chronic obstructive pulmonary disease. N Engl J Med. 2011;365(17):1567-1575.
10. Reid L. The secondary lobule in the adult human lung, with special reference to its appearance in bronchograms. Thorax. 1958;13(2):110-115.
11. Weibel ER. Morphometry of the Human Lung. New York, NY: Academic Press Inc; 1963.
12. Horsfield K, Cumming G. Morphology of the bronchial tree in man. J Appl Physiol. 1968;24(3):373-383.
13. Macklem PT, Mead J. Resistance of central and peripheral airways measured by a retrograde catheter. J Appl Physiol. 1967;22(3):395-401.
14. Yanai M, Sekizawa K, Ohrui T, Sasaki H, Takishima T. Site of airway obstruction in pulmonary disease: direct measurement of intrabronchial pressure. J Appl Physiol. 1992;72(3):1016-1023.
15. Altshuler B, Palmes ED, Yarmus L, Nelson N. Intrapulmonary mixing of gases studied with aerosols. J Appl Physiol. 1959;14(3):321-327.
16. Rohrer F. Der Stromungswiderstand in der menschlichen Atemwegen und der Einfluss der unregelmässigen Verzweigung es Bronchial-systems auf der Atmungsverlauf in vershiedenen Lungenbezinken. Arch Ges Physiol. 1915;162: 225-229.
17. Rohrer F. Physiologie der Atembewegung. In: Bethe A, von Bergmann G, Embden G, et al, eds. Handbuch der Normalen und Pathologischen Physiologie. Berlin, Germany: Springer; 1925: 70-127.
18. Green M. How big are the bronchioles? St Thomas Hosp Gaz. 1965;63: 136-139.
19. Mead J. The lung's "quiet zone". N Engl J Med. 1970;282(23):1318-1319.
20. Macklem PT, Permutt S, eds. The Lung in the Transition Between Health and Disease. New York, NY: Marcel Dekker Inc.; 1979.
21. Fletcher C, Peto R. The natural history of chronic airflow obstruction. BMJ. 1977;1(6077):1645-1648. (Pubitemid 8124466)
22. Cosio M, Ghezzo H, Hogg JC, et al. The relations between structural changes in small airways and pulmonary-function tests. N Engl J Med. 1978;298(23):1277-1281. (Pubitemid 8361451)
23. Van Brabandt H, Cauberghs M, Verbeken E, Moerman P, Lauweryns JM, Van de Woestijne KP. Partitioning of pulmonary impedance in excised human and canine lungs. J Appl Physiol. 1983;55(6):1733-1742. (Pubitemid 14210779)
24. Wagner EM, Liu MC, Weinmann GG, Permutt S, Bleecker ER. Peripheral lung resistance in normal and asthmatic subjects. Am Rev Respir Dis. 1990;141(3):584-588. (Pubitemid 20109142)
25. Wagner EM, Bleecker ER, Permutt S, Liu MC. Direct assessment of small airways reactivity in human subjects. Am J Respir Crit Care Med. 1998;157(2):447-452. (Pubitemid 28090533)
26. Bignon J, Khoury F, Even P, Andre J, Brouet G. Morphometric study in chronic obstructive bronchopulmonary disease. Pathologic, clinical, and physiologic correlations. Am Rev Respir Dis. 1969;99(5):669-695.
27. Matsuba K, Thurlbeck WM. The number and dimensions of small airways in emphysematous lungs. Am J Pathol. 1972;67(2):265-275.
28. Hsia CC, Hyde DM, Ochs M, Weibel ER; ATS/ERS Joint Task Force on Quantitative Assessment of Lung Structure. An official research policy statement of the American Thoracic Society/European Respiratory Society: standards for quantitative assessment of lung structure. Am J Respir Crit Care Med. 2010;181(4):394-418.
29. Findeisen W. Uber das Absetzen kleiner, in dur Luft suspendierter Teilchen in der menschlichen Lunge bei der Atmung. Arch Ges Physiol. 1935;236: 367-379.
30. Leopold JG, Gough J. The centrilobular form of hypertrophic emphysema and its relation to chronic bronchitis. Thorax. 1957;12(3):219-235.
31. McLean KH. The histology of generalized pulmonary emphysema. I. The genesis of the early centrolobular lesion: focal emphysema. Australas Ann Med. 1957;6(2):124-140.
32. Hogg JC, Nepszy SJ, Macklem PT, Thurlbeck WM. Elastic properties of the centrilobular emphysematous space. J Clin Invest. 1969;48(7):1306-1312.
33. Otis AB, McKerrow CB, Bartlett RA, et al. Mechanical factors in distribution of pulmonary ventilation. J Appl Physiol. 1956;8(4):427-443.
34. Hogg JC, Macklem PT, Thurlbeck WM. The resistance of collateral channels in excised human lungs. J Clin Invest. 1969;48(3):421-431.
35. Terry PB, Traystman RJ, Newball HH, Batra G, Menkes HA. Collateral ventilation in man. N Engl J Med. 1978;298(1):10-15. (Pubitemid 8256366)
36. Kirby M, Mathew L, Wheatley A, Santyr GE, McCormack DG, Parraga G. Chronic obstructive pulmonary disease: longitudinal hyperpolarized (3)He MR imaging. Radiology. 2010;256(1):280-289.
37. Marshall H, Deppe MH, Parra-Robles J, et al. Direct visualisation of collateral ventilation in COPD with hyperpolarised gas MRI. Thorax. 2012;67(7):613-617.
38. Yuan R, Hogg JC, Paré PD, et al. Prediction of the rate of decline in FEV(1) in smokers using quantitative computed tomography. Thorax. 2009;64(11):944-949.
39. Mohamed Hoesein FA, de Hoop B, Zanen P, et al. CT-quantified emphysema in male heavy smokers: association with lung function decline. Thorax. 2011;66(9):782-787.
40. Vestbo J, Edwards LD, Scanlon PD, et al ECLIPSE Investigators. Changes in forced expiratory volume in 1 second over time in COPD. N Engl J Med. 2011;365(13):1184-1192.
41. Nishimura M, Makita H, Nagai K, et al Hokkaido COPD Cohort Study Investigators. Annual change in pulmonary function and clinical phenotype in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2012;185(1):44-52.