메뉴 건너뛰기




Volumn 27, Issue 5, 2013, Pages 253-258

Comparative Cytotoxicity, Oxidative Stress, and Cytokine Secretion Induced by Two Cyanotoxin Variants, Microcystin LR and RR, in Human Intestinal Caco-2 Cells

Author keywords

Caco 2; Microcystins; Oxidative Stress; Proinflammatory response

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 8; MICROCYSTIN LR; MICROCYSTIN RR; REACTIVE OXYGEN METABOLITE;

EID: 84877589068     PISSN: 10956670     EISSN: 10990461     Source Type: Journal    
DOI: 10.1002/jbt.21482     Document Type: Article
Times cited : (24)

References (33)
  • 2
    • 0032124844 scopus 로고    scopus 로고
    • The toxicology of microcystins
    • Dawson RM. The toxicology of microcystins. Toxicon 1998;36:953-962.
    • (1998) Toxicon , vol.36 , pp. 953-962
    • Dawson, R.M.1
  • 3
    • 0024453110 scopus 로고
    • Accumulation of a peptide toxin from the cyanobacterium Oscillatoria agardhii in the freshwater mussel Anadonta cygnea
    • Eriksson JE, Meriluoto JAO, Lindholm T. Accumulation of a peptide toxin from the cyanobacterium Oscillatoria agardhii in the freshwater mussel Anadonta cygnea. Hydrobiologia 1989;183:211-216.
    • (1989) Hydrobiologia , vol.183 , pp. 211-216
    • Eriksson, J.E.1    Meriluoto, J.A.O.2    Lindholm, T.3
  • 4
    • 0035204961 scopus 로고    scopus 로고
    • Presence of Planktothrix sp. and cyanobacterial toxins in Lake Ammersee, Germany and their impact on whitefish (Coregonus lavaretus L.)
    • Ernst B, Hitzfeld B, Dietrich D. Presence of Planktothrix sp. and cyanobacterial toxins in Lake Ammersee, Germany and their impact on whitefish (Coregonus lavaretus L.). Environ Toxicol 2001;16:483-488.
    • (2001) Environ Toxicol , vol.16 , pp. 483-488
    • Ernst, B.1    Hitzfeld, B.2    Dietrich, D.3
  • 5
    • 35348901908 scopus 로고    scopus 로고
    • Accumulation of cyanobacterial toxins in freshwater "seafood" and its consequences for public health: a review
    • Ibelings BW, Chorus I. Accumulation of cyanobacterial toxins in freshwater "seafood" and its consequences for public health: a review. Environ Pollut 2007;150:177-192.
    • (2007) Environ Pollut , vol.150 , pp. 177-192
    • Ibelings, B.W.1    Chorus, I.2
  • 6
    • 14644403686 scopus 로고    scopus 로고
    • Guidance values for microcystins in water and cyanobacterial supplement products (blue-green algal supplements): a reasonable or misguided approach
    • Dietrich D, Hoeger S. Guidance values for microcystins in water and cyanobacterial supplement products (blue-green algal supplements): a reasonable or misguided approach? Toxicol Appl Pharmacol 2005;203:273-289.
    • (2005) Toxicol Appl Pharmacol , vol.203 , pp. 273-289
    • Dietrich, D.1    Hoeger, S.2
  • 7
    • 0033944639 scopus 로고    scopus 로고
    • Assessing potential health risks from microcystin toxins in blue-green algae dietary supplements
    • Gilroy DJ, Kauffman KW, Hall RA, Huang X, Chu FS. Assessing potential health risks from microcystin toxins in blue-green algae dietary supplements. Environ Health Perspect 2000;108:435-439.
    • (2000) Environ Health Perspect , vol.108 , pp. 435-439
    • Gilroy, D.J.1    Kauffman, K.W.2    Hall, R.A.3    Huang, X.4    Chu, F.S.5
  • 9
    • 82655188001 scopus 로고    scopus 로고
    • An acute case of intoxication with cyanobacteria and cyanotoxins in recreational water in Salto Grand Dam, Argentina
    • Giannuzzi L, Sedan D, Echenique R, Andrinolo D. An acute case of intoxication with cyanobacteria and cyanotoxins in recreational water in Salto Grand Dam, Argentina. Mar Drugs 2011;9:2164-2175.
    • (2011) Mar Drugs , vol.9 , pp. 2164-2175
    • Giannuzzi, L.1    Sedan, D.2    Echenique, R.3    Andrinolo, D.4
  • 10
  • 11
    • 33745991801 scopus 로고    scopus 로고
    • Oral toxicity of the microcystin-containing cyanobacterium Planktothrix rubescens in European whitefish (Coregonus lavaretus)
    • Ernst B, Hoeger SJ, O'Brien E, Dietrich DR. Oral toxicity of the microcystin-containing cyanobacterium Planktothrix rubescens in European whitefish (Coregonus lavaretus). Aquat Toxicol 2006;79:31-40.
    • (2006) Aquat Toxicol , vol.79 , pp. 31-40
    • Ernst, B.1    Hoeger, S.J.2    O'Brien, E.3    Dietrich, D.R.4
  • 12
    • 0034176293 scopus 로고    scopus 로고
    • Pathological and biochemical characterization of microcystin-induced hepatopancreas and kidney damage in carp (Cyprinus carpio)
    • Fischer WJ, Dietrich DR. Pathological and biochemical characterization of microcystin-induced hepatopancreas and kidney damage in carp (Cyprinus carpio). Toxicol Appl Pharmacol 2000;164:73-81.
    • (2000) Toxicol Appl Pharmacol , vol.164 , pp. 73-81
    • Fischer, W.J.1    Dietrich, D.R.2
  • 13
    • 0033991094 scopus 로고    scopus 로고
    • First report on the distribution of orally administered microcystin-LR in mouse tissue using an immunostaining method
    • Ito E, Kondo F, Harada KI. First report on the distribution of orally administered microcystin-LR in mouse tissue using an immunostaining method. Toxicon 2000;38:37-48.
    • (2000) Toxicon , vol.38 , pp. 37-48
    • Ito, E.1    Kondo, F.2    Harada, K.I.3
  • 14
    • 1242314785 scopus 로고    scopus 로고
    • The role of microcystin-LR in the induction of apoptosis and oxidative stress in Caco-2 cells
    • Botha N, Gehringer MM, Downing TG, van de Venter M, Shephard EG. The role of microcystin-LR in the induction of apoptosis and oxidative stress in Caco-2 cells. Toxicon 2004;43:85-92.
    • (2004) Toxicon , vol.43 , pp. 85-92
    • Botha, N.1    Gehringer, M.M.2    Downing, T.G.3    van de Venter, M.4    Shephard, E.G.5
  • 15
    • 72749122904 scopus 로고    scopus 로고
    • Differential oxidative stress responses to pure microcystin-LR and microcystin-containing and non-containing cyanobacterial crude extracts on Caco-2 cells
    • Puerto M, Pichardo S, Jos A, Prieto AI, Sevilla E, Frias JE, Cameán AM. Differential oxidative stress responses to pure microcystin-LR and microcystin-containing and non-containing cyanobacterial crude extracts on Caco-2 cells. Toxicon 2010;55:514-522.
    • (2010) Toxicon , vol.55 , pp. 514-522
    • Puerto, M.1    Pichardo, S.2    Jos, A.3    Prieto, A.I.4    Sevilla, E.5    Frias, J.E.6    Cameán, A.M.7
  • 16
    • 50549083214 scopus 로고    scopus 로고
    • Different sensitivities of human colon adenocarcinoma Caco-2, astrocytoma (IPDDC-A2) and lymphoblastoid (NCNC) cell lines to microcystin-LR induced reactive oxygen species and DNA damage
    • Zegura B, Volcic M, Lah TT, Filipic M. Different sensitivities of human colon adenocarcinoma Caco-2, astrocytoma (IPDDC-A2) and lymphoblastoid (NCNC) cell lines to microcystin-LR induced reactive oxygen species and DNA damage. Toxicon 2008;52:518-525.
    • (2008) Toxicon , vol.52 , pp. 518-525
    • Zegura, B.1    Volcic, M.2    Lah, T.T.3    Filipic, M.4
  • 17
    • 65749086670 scopus 로고    scopus 로고
    • Comparison of the toxicity induced by microcystin-RR and microcystin-YR in differentiated and undifferentiated Caco-2 cells
    • Puerto M, Pichardo S, Jos A, Cameán AM. Comparison of the toxicity induced by microcystin-RR and microcystin-YR in differentiated and undifferentiated Caco-2 cells. Toxicon 2009;54:161-169.
    • (2009) Toxicon , vol.54 , pp. 161-169
    • Puerto, M.1    Pichardo, S.2    Jos, A.3    Cameán, A.M.4
  • 18
    • 77952096858 scopus 로고    scopus 로고
    • Microcystin-LR induces toxic effects in differentiated and undifferentiated Caco-2 cells
    • Puerto M, Pichardo S, Jos A, Cameán AM. Microcystin-LR induces toxic effects in differentiated and undifferentiated Caco-2 cells. Arch Toxicol 2010;84:405-410.
    • (2010) Arch Toxicol , vol.84 , pp. 405-410
    • Puerto, M.1    Pichardo, S.2    Jos, A.3    Cameán, A.M.4
  • 19
    • 80053633597 scopus 로고    scopus 로고
    • Similar uptake profiles of microcystin-LR and -RR in an in vitro human intestinal model
    • Zeller P, Clement M, Fessard V. Similar uptake profiles of microcystin-LR and -RR in an in vitro human intestinal model. Toxicology 2011;290:7-13.
    • (2011) Toxicology , vol.290 , pp. 7-13
    • Zeller, P.1    Clement, M.2    Fessard, V.3
  • 20
    • 84863008112 scopus 로고    scopus 로고
    • Transcriptomic comparison of cyanotoxin variants in a human intestinal model revealed major differences in oxidative stress response: effects of MC-RR and MC-LR on Caco-2 cells
    • Zeller P, Quenault H, Huguet A, Blanchard Y, Fessard V. Transcriptomic comparison of cyanotoxin variants in a human intestinal model revealed major differences in oxidative stress response: effects of MC-RR and MC-LR on Caco-2 cells. Ecotoxicol Environ Saf 2012;82:13-21.
    • (2012) Ecotoxicol Environ Saf , vol.82 , pp. 13-21
    • Zeller, P.1    Quenault, H.2    Huguet, A.3    Blanchard, Y.4    Fessard, V.5
  • 21
    • 80052535624 scopus 로고    scopus 로고
    • Dimethyl sulfoxide (DMSO) attenuates the inflammatory response in the in vitro intestinal Caco-2 cell model
    • Hollebeeck S, Raas T, Piront N, Schneider Y, Toussaint O, Larondelle Y, During A. Dimethyl sulfoxide (DMSO) attenuates the inflammatory response in the in vitro intestinal Caco-2 cell model. Toxicol Lett 2011;206:268-275.
    • (2011) Toxicol Lett , vol.206 , pp. 268-275
    • Hollebeeck, S.1    Raas, T.2    Piront, N.3    Schneider, Y.4    Toussaint, O.5    Larondelle, Y.6    During, A.7
  • 22
    • 40849101434 scopus 로고    scopus 로고
    • Both direct and indirect effects account for the pro-inflammatory activity of enteropathogenic mycotoxins on the human intestinal epithelium: stimulation of interleukin-8 secretion, potentiation of interleukin-1β effect and increase in the transepithelial passage of commensal bacteria
    • Maresca M, Yahi N, Younes-Sakr L, Boyron M, Caporiccio B, Fantini J. Both direct and indirect effects account for the pro-inflammatory activity of enteropathogenic mycotoxins on the human intestinal epithelium: stimulation of interleukin-8 secretion, potentiation of interleukin-1β effect and increase in the transepithelial passage of commensal bacteria. Toxicol Appl Pharmacol 2008;228:84-92.
    • (2008) Toxicol Appl Pharmacol , vol.228 , pp. 84-92
    • Maresca, M.1    Yahi, N.2    Younes-Sakr, L.3    Boyron, M.4    Caporiccio, B.5    Fantini, J.6
  • 23
    • 20044371666 scopus 로고    scopus 로고
    • The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics
    • Sambuy Y, De Angelis I, Ranaldi G, Scarino ML, Stammati A, Zucco F. The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics. Cell Biol Toxicol 2005;21:1-26.
    • (2005) Cell Biol Toxicol , vol.21 , pp. 1-26
    • Sambuy, Y.1    De Angelis, I.2    Ranaldi, G.3    Scarino, M.L.4    Stammati, A.5    Zucco, F.6
  • 24
    • 73249127370 scopus 로고    scopus 로고
    • Oxidative stress generation by microcystins in aquatic animals: why and how
    • Amado LL, Monserrat JM. Oxidative stress generation by microcystins in aquatic animals: why and how. Environ Int 2010;36:226-235.
    • (2010) Environ Int , vol.36 , pp. 226-235
    • Amado, L.L.1    Monserrat, J.M.2
  • 25
    • 28744446756 scopus 로고    scopus 로고
    • Differential detoxification and antioxidant response in diverse organs of Corydoras paleatus experimentally exposed to microcystin-RR
    • Cazenave J, Bistoni MDLA, Pesce SF, Wunderlin DA. Differential detoxification and antioxidant response in diverse organs of Corydoras paleatus experimentally exposed to microcystin-RR. Aquat Toxicol 2006;76:1-12.
    • (2006) Aquat Toxicol , vol.76 , pp. 1-12
    • Cazenave, J.1    Bistoni, M.D.L.A.2    Pesce, S.F.3    Wunderlin, D.A.4
  • 26
    • 24344438661 scopus 로고    scopus 로고
    • Microcystin-RR-induced accumulation of reactive oxygen species and alteration of antioxidant systems in tobacco BY-2 cells
    • Yin L, Huang J, Huang W, Li D, Wang G, Liu Y. Microcystin-RR-induced accumulation of reactive oxygen species and alteration of antioxidant systems in tobacco BY-2 cells. Toxicon 2005;46:507-512.
    • (2005) Toxicon , vol.46 , pp. 507-512
    • Yin, L.1    Huang, J.2    Huang, W.3    Li, D.4    Wang, G.5    Liu, Y.6
  • 27
    • 33646114525 scopus 로고    scopus 로고
    • Differential oxidative stress responses to microcystins LR and RR in intraperitoneally exposed tilapia fish (Oreochromis sp.)
    • Prieto AI, Jos A, Pichardo S, Moreno I, Cameán AM. Differential oxidative stress responses to microcystins LR and RR in intraperitoneally exposed tilapia fish (Oreochromis sp.). Aquat Toxicol 2006;77:314-321.
    • (2006) Aquat Toxicol , vol.77 , pp. 314-321
    • Prieto, A.I.1    Jos, A.2    Pichardo, S.3    Moreno, I.4    Cameán, A.M.5
  • 28
    • 84862948067 scopus 로고    scopus 로고
    • In vivo studies on the immunotoxic effects of microcystins on rabbit
    • Yuan G, Xie P, Zhang X, Tang R, Gao Y, Li D, Li L. In vivo studies on the immunotoxic effects of microcystins on rabbit. Environ Toxicol 2012;27:83-89.
    • (2012) Environ Toxicol , vol.27 , pp. 83-89
    • Yuan, G.1    Xie, P.2    Zhang, X.3    Tang, R.4    Gao, Y.5    Li, D.6    Li, L.7
  • 30
    • 79960691818 scopus 로고    scopus 로고
    • Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis
    • Boots AW, Drent M, de Boer VC, Bast A, Haenen GR. Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis. Clin Nutr 2011;30:506-512.
    • (2011) Clin Nutr , vol.30 , pp. 506-512
    • Boots, A.W.1    Drent, M.2    de Boer, V.C.3    Bast, A.4    Haenen, G.R.5
  • 32
    • 77956801100 scopus 로고    scopus 로고
    • 7-Ketocholesterol-induced inflammation: involvement of multiple kinase signaling pathways via NFκB but independently of reactive oxygen species formation
    • Larrayoz IM, Huang JD, Lee JW, Pascual I, Rodriguez IR. 7-Ketocholesterol-induced inflammation: involvement of multiple kinase signaling pathways via NFκB but independently of reactive oxygen species formation. Invest Ophthalmol Visual Sci 2010;51:4942-4955.
    • (2010) Invest Ophthalmol Visual Sci , vol.51 , pp. 4942-4955
    • Larrayoz, I.M.1    Huang, J.D.2    Lee, J.W.3    Pascual, I.4    Rodriguez, I.R.5
  • 33
    • 77956172500 scopus 로고    scopus 로고
    • Microcystin-LR activates the ERK1/2 kinases and stimulates the proliferation of the monkey kidney-derived cell line Vero-E6
    • Dias E, Matos P, Pereira P, Batoreu MCC, Silva MJ, Jordan P. Microcystin-LR activates the ERK1/2 kinases and stimulates the proliferation of the monkey kidney-derived cell line Vero-E6. Toxicol In Vitro 2010;24:1689-1695.
    • (2010) Toxicol In Vitro , vol.24 , pp. 1689-1695
    • Dias, E.1    Matos, P.2    Pereira, P.3    Batoreu, M.C.C.4    Silva, M.J.5    Jordan, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.