RET/PTC and PAX8/PPARγ chromosomal rearrangements in post-Chernobyl thyroid cancer and their association with iodine-131 radiation dose and other characteristics

Cancer

Volumn 119, Issue 10, 2013, Pages 1792-1799

  Leeman Neill, Rebecca J ^a   Brenner, Alina V ^b   Little, Mark P ^b   Bogdanova, Tetiana I ^c   Hatch, Maureen ^b   Zurnadzy, Liudmyla Y ^c   Mabuchi, Kiyohiko ^b   Tronko, Mykola D ^c   Nikiforov, Yuri E ^a  

^a PRESBYTERIAN UNIVERSITY HOSPITAL   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c STATE INSTITUTION NATIONAL RESEARCH CENTER FOR RADIATION MEDICINE OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE   (Ukraine)

Author keywords

Chernobyl; iodine 131; papillary thyroid carcinoma; PAX8 PPAR ; RET PTC

Indexed keywords

B RAF KINASE; IODINE 131; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RAS PROTEIN; TRANSCRIPTION FACTOR PAX8;

ADULT; ARTICLE; BRAF GENE; CANCER PATIENT; CHERNOBYL ACCIDENT; CHROMOSOME REARRANGEMENT; COHORT ANALYSIS; FEMALE; GENE ACTIVITY; GENE FUNCTION; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; HUMAN; IODINE DEFICIENCY; MAJOR CLINICAL STUDY; MALE; ONCOGENE; ONCOGENE RAS; PATHOPHYSIOLOGY; PAX8 GENE; PPAR GAMMA GENE; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; RET GENE; THYROID CARCINOMA; UKRAINE;

ADOLESCENT; ADULT; CARCINOMA; CHERNOBYL NUCLEAR ACCIDENT; CHILD; DEFICIENCY DISEASES; DNA MUTATIONAL ANALYSIS; FEMALE; GENE REARRANGEMENT; HUMANS; IODINE; IODINE RADIOISOTOPES; MALE; MULTIVARIATE ANALYSIS; ODDS RATIO; PAIRED BOX TRANSCRIPTION FACTORS; POINT MUTATION; PPAR GAMMA; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS C-RET; RADIATION INJURIES; THYROID NEOPLASMS; TIME FACTORS; UKRAINE;

EID: 84877585803     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.27893     Document Type: Article

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