Certain types of iron oxide nanoparticles are not suited to passively target inflammatory cells that infiltrate the brain in response to stroke

Journal of Cerebral Blood Flow and Metabolism

Volumn 33, Issue 5, 2013, Pages

  Harms, Christoph ^a   Datwyler, Anna Lena ^a   Wiekhorst, Frank ^b   Trahms, Lutz ^b   Lindquist, Randall ^a   Schellenberger, Eyk ^a   Mueller, Susanne ^a   Schütz, Gunnar ^c   Roohi, Farnoosh ^c   Ide, Andreas ^c   Füchtemeier, Martina ^a   Gertz, Karen ^a   Kronenberg, Golo ^a   Harms, Ulrike ^a   Endres, Matthias ^a   Dirnagl, Ulrich ^a   Farr, Tracy D ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b PHYSIKALISCH TECHNISCHE BUNDESANSTALT   (Germany)

^c BAYER PHARMA AG   (Germany)

Author keywords

inflammation; iron oxide nanoparticles; magnetic resonance imaging; stroke

Indexed keywords

GADOLINIUM PENTETATE MEGLUMINE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; HISTOLOGY; IMAGE ANALYSIS; INFLAMMATORY CELL; INFLAMMATORY INFILTRATE; LEUKOCYTE; LIVER; MAGNETIC PARTICLE SPECTROSCOPY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; PHAGOCYTOSIS; PRIORITY JOURNAL; REPERFUSION; SPECTROSCOPY; SPLEEN; ZETA POTENTIAL;

ANIMALS; BRAIN; CONTRAST MEDIA; INFARCTION, MIDDLE CEREBRAL ARTERY; LEUKOCYTES; MAGNETIC RESONANCE IMAGING; MAGNETITE NANOPARTICLES; MALE; MICE; MICE, INBRED C57BL; PARTICLE SIZE; PHAGOCYTOSIS;

EID: 84877582336     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2013.22     Document Type: Article

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