Novel single-nucleotide polymorphism markers predictive of pathologic response to preoperative chemoradiation therapy in rectal cancer patients

International Journal of Radiation Oncology Biology Physics

Volumn 86, Issue 2, 2013, Pages 350-357

  Kim, Jin C ^a,b   Ha, Ye J ^a,b   Roh, Seon A ^a,b   Cho, Dong H ^b,c   Choi, Eun Y ^a,b   Kim, Tae W ^a,b   Kim, Jong H ^a   Kang, Tae W ^d   Kim, Seon Y ^b,d   Kim, Yong S ^b,d  

^a University of Ulsan College of Medicine   (South Korea)

^b Asan Medical Center   (South Korea)

^c Kyung Hee University   (South Korea)

^d Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ASSOCIATION ANALYSIS; BIOLOGICAL VALIDATIONS; COLORECTAL CANCER CELL; METHODS AND MATERIALS; PREOPERATIVE CHEMORADIATION; SINGLE-NUCLEOTIDE POLYMORPHISM MARKERS; SINGLE-NUCLEOTIDE POLYMORPHISMS; TUMOR REGRESSION GRADES;

ASSAYS; BIOLOGICAL MATERIALS; CHEMORADIOTHERAPY; DIAGNOSIS; DISEASES; FLOW CYTOMETRY; GENES; NUCLEOTIDES; PATIENT MONITORING;

CELL DEATH;

CAPECITABINE; FLUOROURACIL; FOLINIC ACID;

ADULT; APOPTOSIS; ARTICLE; CANCER CELL; CHEMORADIOTHERAPY; CORO2A GENE; CYTOTOXICITY; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC SCREENING; GENOTYPING TECHNIQUE; HUMAN; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; MULTIMODALITY CANCER THERAPY; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; PYROSEQUENCING; RADIATION DOSE FRACTIONATION; RADIOSENSITIVITY; RECTUM CANCER; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT RESPONSE; TUMOR REGRESSION;

ALLELES; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CELL LINE, TUMOR; CHEMORADIOTHERAPY; DEOXYCYTIDINE; FEMALE; FLUOROURACIL; GENETIC MARKERS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPING TECHNIQUES; HUMANS; LEUCOVORIN; MALE; MICROFILAMENT PROTEINS; MIDDLE AGED; PREOPERATIVE CARE; RADIATION TOLERANCE; RECTAL NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 84877578854     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2012.12.018     Document Type: Article

References (19)

1. J.G. Guillem, D.B. Chessin, and A.M. Cohen Long-term oncologic outcome following preoperative combined modality therapy and total mesorectal excision of locally advanced rectal cancer Ann Surg 241 2005 829 836
2. M.S. Roh, L.H. Colangelo, and M.J. O'Connell Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABPR-03 J Clin Oncol 27 2009 5124 5130
3. J.H. Park, S.M. Yoon, and C.S. Yu Randomized phase 3 trial comparing preoperative and postoperative chemoradiotherapy with capecitabine for locally advanced rectal cancer Cancer 117 2011 3703 3712
4. J.G. Kuremsky, J.E. Tepper, and H.L. McLeod Biomarkers for response to neoadjuvant chemoradiation for rectal cancer Int J Radiat Oncol Biol Phys 74 2009 673 688
5. M.Y. Huang, J.Y. Wang, and H.J. Chang CDC25A, VAV1, TP73, BRCA1 and ZAP70 gene overexpression correlates with radiation response in colorectal cancer Oncol Rep 25 2011 1297 1306
6. B.M. Ghadimi, M. Grade, and M.J. Difilippantonio Effectiveness of gene expression profiling for response prediction of rectal adenocarcinomas to preoperative chemoradiotherapy J Clin Oncol 23 2005 1826 1838
7. C. Rimkus, J. Friederichs, and A.L. Boulesteix Microarray-based prediction of tumor response to neoadjuvant radiochemotherapy of patients with locally advanced rectal cancer Clin Gastroenterol Hepatol 6 2008 53 61
8. A.C. Begg Predicting response to radiotherapy: evolutions and revolutions Int J Radiat Biol 85 2009 825 836
9. G. Della Vittoria Scarpati, F. Falcetta, and C. Carlomagno A specific miRNA signature correlates with complete pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer Int J Radiat Oncol Biol Phys 83 2012 1113 1119
10. A.M. Mandard, F. Dalibard, and J.C. Mandard Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma: clinicopathologic correlations Cancer 73 1994 2680 2686
11. S. Purcell, B. Neale, and K. Todd-Brown PLINK: a tool set for whole-genome association and population-based linkage analyses Am J Hum Genet 81 2007 559 575
12. A.D. Johnson, R.E. Handsaker, and S.L. Pulit SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap Bioinformatics 24 2008 2938 2939
13. B.A. Rupnow, and S.J. Knox The role of radiation-induced apoptosis as a determinant of tumor responses to radiation therapy Apoptosis 4 1999 115 143
14. J. Muppidi, M. Porter, and R.M. Siegel Measurement of apoptosis and other forms of cell death Curr Protoc Immunol Supp 59 3.17 2004 1 36
15. V.N. Sumantran Cellular chemosensitivity assays: an overview Methods Mol Biol 731 2011 219 236
16. L. Smith Post-transcriptional regulation of gene expression by alternative 5′-untranslated regions in carcinogenesis Biochem Soc Trans 36 2008 708 711
17. J.C. Kim, S.Y. Kim, and D.H. Cho Novel chemosensitive single-nucleotide polymorphism markers to targeted regimens in metastatic colorectal cancer Clin Cancer Res 17 2011 1200 1209
18. H.G. Yoon, D.W. Chan, and A.B. Reynolds N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso Mol Cell 12 2003 723 734
19. W. Huang, S. Ghisletti, and K. Saijo Coronin 2A mediates actin-dependent de-repression of inflammatory response genes Nature 470 2011 414 418