Chalcones, inhibitors for topoisomerase i and cathepsin B and L, as potential anti-cancer agents

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 11, 2013, Pages 3320-3324

  Kim, Seok Ho ^a   Lee, Eunyoung ^b   Baek, Kyung Hye ^b   Kwon, Han Byeol ^b   Woo, Hyunjung ^b   Lee, Eung Seok ^c   Kwon, Youngjoo ^b   Na, Younghwa ^a  

^a Cha University   (South Korea)

^b Ewha Womans University   (South Korea)

^c Yeungnam University   (South Korea)

Author keywords

Cathepsin Band L; Chalcone; Cytotoxicity; Topoisomerase I

Indexed keywords

ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CATHEPSIN B INHIBITOR; CHALCONE DERIVATIVE; DNA TOPOISOMERASE INHIBITOR; DOXORUBICIN; ETOPOSIDE;

ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; HUMAN; HUMAN CELL; IC 50; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CATHEPSIN B; CATHEPSIN L; CELL LINE, TUMOR; CELL SURVIVAL; CHALCONES; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; ENZYME INHIBITORS; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP; TOPOISOMERASE I INHIBITORS;

EID: 84877578310     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.03.106     Document Type: Article

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