Immnunohistocheinical study of the effect of resveratrol on the expression of β-catenin protein in experimental colonic carcinoma of rat

Journal of Animal and Veterinary Advances

Volumn 11, Issue 23, 2012, Pages 4472-4475

  Doustar, Yousef ^a   Garjani, Alireza ^b  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b UNIVERSITY OF TABRIZ   (Iran)

Author keywords

catenin proteins; Colon carcinoma; Ketamine; Rat; Resveratrol

Indexed keywords

EID: 84877346340     PISSN: 16805593     EISSN: 1993601X     Source Type: Journal    
DOI: 10.3923/javaa.2012.4472.4475     Document Type: Article

References (23)

1. Boros, L.G., P.W. Lee, J.L. Brandes, M. Cascante and P. Muscarella et al, 1998. Nonoxidative pentose phosphate pathways and their direct role in nbose synthesis in tumors: Is cancer a disease of cellular glucose metabolism? Med. Hypotheses, 50: 55-59.
2. Cancer Genome Atlas Network, 2012. Comprehensive molecular characterization of human colon and rectal cancer. Nature, 487: 330-337.
3. De laLastra, C.A. and I Villegas, 2007. Resveratrol as an antioxidant and pro-oxidant agent: Mechanisms and clinical implications. Biochem. Soc. Trans., 35: 1156-1160.
4. Desbois-Moufhon, C, A. Cadoret, M.J. Blivet-Van Eggelpoel, F. Bertrand, G. Cherqui, C. Perret and J. Capeau, 2001. Insulin and IGF-1 stimulate the beta-catemn pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation. Oncogene, 20: 252-259.
5. Dudley, J., S. Das, S. Mukherjee and D.K. Das, 2009. Resveratrol, a unique phytoalexin present in red wine, delivers either survival signal or death signal to the ischemic myocardium depending on dose. J. Nutr. Biochem., 20: 443-452.
6. Dupont, J., A. Pierre, P. Fromentand C. Moreau, 2003. The insulin-like growth factor axis in cell cycle progression. Horm. Metab. Res., 35: 740-750.
7. Ferlay, J., H.R. Shin, F. Bray, D. Forman, C. Mathers and D.M. Parkin, 2010. Colorectal cancer incidence, mortality and prevalence worldwide in 2008. International Agency for Research on Cancer, Lyon, France.
8. Ferlay, J., P. Autier, M. Boniol, M. Heanue, M. Colombet and P. Boyle, 2007. Estimates of the cancer incidence and mortality in Europe in 2006. Ann. Oncol., 18: 581-592.
9. Hart, L.S., N.G. Dolloff, D.T. Dicker, C. Koumems, J.G. Chnstensen, A. Grimberg and W.S. El-Deiry, 2011. Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab. Cell Cycle, 10: 2331-2338.
10. Juan, M.E., U. Wenzel, H. Daniel and J.M. Planas, 2008. Resveratrol induces apoptosis through ROS-dependent mitochondria pathway in HT-29 human colorectal carcinoma cells. J. Agric. Food Chem., 56: 4813-4818.
11. Kraus, C, T. Liehr, J. Hulsken, J. Behrens, W. Birchmeier, K.H. Grzeschik and W.G. Ballhausen, 1994. Localization of the human β-catenin gene (CTNNB1) to 3p21: A region implicated in tumor development. Genomics, 23: 272-274.
12. Laurino, L., Wang, B.A. de la Houssaye, L. Sosa and S. Dupraz et al, 2005. PI3K activation by IGF-1 is essential for the regulation of membrane expansion at the nerve growth cone. J. Cell. Sci., 118: 3653-3662.
13. MacDonald, B.T., K. Tamai andX. He, 2009. Wnt/beta-catemn signaling: Components, mechanisms and diseases. Dev. Cell, 17: 9-26.
14. Mukherjee, S., J.I. Dudley and D.K. Das, 2010. Dose-dependency of resveratrol in providing health benefits. Dose Response, 8: 478-500.
15. Noordermeer, J., J. Klingensmith, N. Perrimon and R. Nusse, 1994. Dishevelled and Armadillo act in the wingless signalling pathway in Drosophila. Nature, 367: 80-83.
16. Peifer, M., C. Rauskolb, M. Williams, B. Riggleman and E. Wieschaus, 1991. The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation. Development, 111: 1029-1043.
17. Peifer, M., S. Berg and A.B. Reynolds, 1994. A repeating amino acid motif shared by proteins with diverse cellular roles. Cell, 76: 789-791.
18. Ramos-Montoya, A., W.N. Lee, S. Bassihan, S. Lim and R.V. Trebukhina et al., 2006. Pentose phosphate cycle oxidative and nonoxidative balance: A new vulnerable target for overcoming drug resistance in cancer. Int. J. Cancer, 119: 2733-2741.
19. Saldanha, G., V. Ghura, L. Potter and A. Fletcher, 2004. Nuclear p-catenin in basal cell carcinoma correlates with increased proliferation. Br. J. Dermatol., 151: 157-164.
20. Thompson, M.D. and S.P. Monga, 2007. WNT/β-catenin signaling in liver health and disease. Hepatology, 45: 1298-1305.
21. Vanamala, J., L. Reddivari, S. Radhakrishnan and C. Tarver, 2010. Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways. BMC Cancer, Vol. 10. 10.1186/1471-2407-10-238.
22. Vizan, P., G. Alcarraz-Vizan, S. Diaz-Moralli, O.N. Solovjeva, W.M. Frederiks and M. Cascante, 2009. Modulation of pentose phosphate pathway during cell cycle progression in human colon adenocarcinoma cell line HT29. Int. J. Cancer, 124:2789-2796.
23. Wang, X., E.L. Goode, Z.S. Fredericksen, R.A. Vierkant and V.S. Pankratz et al., 2008. Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer. Cancer Epidemiol. Biomarkers Prev., 17: 2101-2108.