-
1
-
-
70249101414
-
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: Results of a randomized Phase II study of two different schedules
-
Demetri GD, Chawla SP, von Mehren M et al. Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized Phase II study of two different schedules. J. Clin. Oncol. 27(25), 4188-4196 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.25
, pp. 4188-4196
-
-
Demetri, G.D.1
Chawla, S.P.2
Von Mehren, M.3
-
2
-
-
0036189675
-
Progression-free rate as the principal end-point for Phase II trials in soft tissue sarcomas
-
EORTC Soft Tissue and Bone Sarcoma Group
-
Van Glabbeke M, Verweij J, Judson I, Nielsen OS; EORTC Soft Tissue and Bone Sarcoma Group. Progression-free rate as the principal end-point for Phase II trials in soft tissue sarcomas. Eur. J. Cancer 38(4), 543-549 (2002).
-
(2002)
Eur. J. Cancer
, vol.38
, Issue.4
, pp. 543-549
-
-
Van Glabbeke, M.1
Verweij, J.2
Judson, I.3
Nielsen, O.S.4
-
3
-
-
70350068771
-
Mapping the literature: Role of trabectedin as a new chemotherapy option in advanced pretreated soft tissue sarcoma
-
Le Cesne A, Domont J, Cioffi A et al. Mapping the literature: role of trabectedin as a new chemotherapy option in advanced pretreated soft tissue sarcoma. Drugs Today (Barc). 45(6), 403-421 (2009).
-
(2009)
Drugs Today (Barc)
, vol.45
, Issue.6
, pp. 403-421
-
-
Le Cesne, A.1
Domont, J.2
Cioffi, A.3
-
4
-
-
20044372153
-
Phase II study of ET-743 in advanced soft tissue sarcomas: a European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial
-
Le Cesne A, Blay JY, Judson I et al. Phase II study of ET-743 in advanced soft tissue sarcomas: a European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial. J. Clin. Oncol. 23(3), 576-584 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.3
, pp. 576-584
-
-
Le Cesne, A.1
Blay, J.Y.2
Judson, I.3
-
5
-
-
1542398698
-
Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients
-
Yovine A, Riofrio M, Blay JY et al. Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients. J. Clin. Oncol. 22(5), 890-899 (2004).
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.5
, pp. 890-899
-
-
Yovine, A.1
Riofrio, M.2
Blay, J.Y.3
-
6
-
-
2342461682
-
Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy
-
Garcia-Carbonero R, Supko JG, Manola J et al. Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy. J. Clin. Oncol. 22(8), 1480-1490 (2004).
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.8
, pp. 1480-1490
-
-
Garcia-Carbonero, R.1
Supko, J.G.2
Manola, J.3
-
7
-
-
0242522296
-
Therapeutic impact of ET-743 (Yondelis; trabectedin), a new marine-derived compound, in sarcoma
-
Jimeno J, Maki RG, Casali P et al. Therapeutic impact of ET-743 (Yondelis; trabectedin), a new marine-derived compound, in sarcoma. Curr. Opin. Orthop. 14(6), 419-428 (2003).
-
(2003)
Curr. Opin. Orthop.
, vol.14
, Issue.6
, pp. 419-428
-
-
Jimeno, J.1
Maki, R.G.2
Casali, P.3
-
8
-
-
57349160298
-
Translating targets into treatment: Changes in trial methodology and treatment approaches for soft tissue sarcomas
-
Perry MC (Ed.) American Society of Clinical Oncology, Alexandria, VA, USA
-
Verweij J, van Glabbeke M. Translating targets into treatment: changes in trial methodology and treatment approaches for soft tissue sarcomas. In: Classification and Treatment of Soft Tissue Sarcomas Educational Book. Perry MC (Ed.). American Society of Clinical Oncology, Alexandria, VA, USA, 522-530 (2003).
-
(2003)
Classification and Treatment of Soft Tissue Sarcomas Educational Book
, pp. 522-530
-
-
Verweij, J.1
Van Glabbeke, M.2
-
9
-
-
79957579501
-
Topoisomerase II-alpha protein expression and histological response following doxorubicin-based induction chemotherapy predict survival of locally advanced soft tissues sarcomas
-
Ruiz-Soto R, Auger N, Tournay E. Topoisomerase II-alpha protein expression and histological response following doxorubicin-based induction chemotherapy predict survival of locally advanced soft tissues sarcomas. Eur. J. Cancer 47(9), 1319-1327 (2011).
-
(2011)
Eur. J. Cancer
, vol.47
, Issue.9
, pp. 1319-1327
-
-
Ruiz-Soto, R.1
Auger, N.2
Tournay, E.3
-
10
-
-
34347214071
-
Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: A retrospective study
-
Grosso F, Jones RL, Demetri GD et al. Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study. Lancet Oncol. 8(7), 595-602 (2007).
-
(2007)
Lancet Oncol
, vol.8
, Issue.7
, pp. 595-602
-
-
Grosso, F.1
Jones, R.L.2
Demetri, G.D.3
-
11
-
-
84873733013
-
Growth modulation index as metric of clinical benefit assessment among advanced soft tissue sarcoma patients receiving trabectedin as a salvage therapy
-
Penel N, Demetri GD, Blay JY et al. Growth modulation index as metric of clinical benefit assessment among advanced soft tissue sarcoma patients receiving trabectedin as a salvage therapy. Ann. Oncol. 24(2), 537-42 (2012).
-
(2012)
Ann. Oncol.
, vol.24
, Issue.2
, pp. 537-542
-
-
Penel, N.1
Demetri, G.D.2
Blay, J.Y.3
-
12
-
-
84877309364
-
Growth modulation index and RECIST-based STBSG-EORTC criteria for the assessment of drug activity in advanced soft tissue sarcoma (ASTS) patients (pts)
-
Abstract 10014
-
Cousin S, Blay JY, Bertucci F et al. Growth modulation index and RECIST-based STBSG-EORTC criteria for the assessment of drug activity in advanced soft tissue sarcoma (ASTS) patients (pts). J. Clin. Oncol. 30(Suppl.), Abstract 10014 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.SUPPL.
-
-
Cousin, S.1
Blay, J.Y.2
Bertucci, F.3
-
13
-
-
84864348875
-
A retrospective pooled analysis of trabectedin safety in 1,132 patients with solid tumors treated in Phase II clinical trials
-
Le Cesne A, Yovine A, Blay JY et al. A retrospective pooled analysis of trabectedin safety in 1,132 patients with solid tumors treated in Phase II clinical trials. Invest. New Drugs 30(3), 1193-1202 (2012).
-
(2012)
Invest. New Drugs
, vol.30
, Issue.3
, pp. 1193-1202
-
-
Le Cesne, A.1
Yovine, A.2
Blay, J.Y.3
-
14
-
-
18144448739
-
Randomized Phase II study of docetaxel versus doxorubicin in first- and second-line chemotherapy for locally advanced or metastatic soft tissue sarcomas in adults: A study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
-
Verweij J, Lee SM, Ruka W et al. Randomized Phase II study of docetaxel versus doxorubicin in first- and second-line chemotherapy for locally advanced or metastatic soft tissue sarcomas in adults: a study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group. J. Clin. Oncol. 18(10), 2081-2086 (2000).
-
(2000)
J. Clin. Oncol.
, vol.18
, Issue.10
, pp. 2081-2086
-
-
Verweij, J.1
Lee, S.M.2
Ruka, W.3
-
15
-
-
18844475497
-
Effect of high-dose ifosfamide in advanced soft tissue sarcomas. A multicentre Phase II study of the EORTC Soft Tissue and Bone Sarcoma Group
-
Nielsen OS, Judson I, van Hoesel Q et al. Effect of high-dose ifosfamide in advanced soft tissue sarcomas. A multicentre Phase II study of the EORTC Soft Tissue and Bone Sarcoma Group. Eur. J. Cancer 36(1), 61-67 (2000).
-
(2000)
Eur. J. Cancer
, vol.36
, Issue.1
, pp. 61-67
-
-
Nielsen, O.S.1
Judson, I.2
Van Hoesel, Q.3
-
16
-
-
18844475615
-
Randomised Phase II trial of PEGylated liposomal doxorubicin (DOXIL/CAELYX) versus doxorubicin in the treatment of advanced or metastatic soft tissue sarcoma: A study by the EORTC Soft Tissue and Bone Sarcoma Group
-
Judson I, Radford JA, Harris M et al. Randomised Phase II trial of PEGylated liposomal doxorubicin (DOXIL/CAELYX) versus doxorubicin in the treatment of advanced or metastatic soft tissue sarcoma: a study by the EORTC Soft Tissue and Bone Sarcoma Group. Eur. J. Cancer 37(7), 870-877 (2001).
-
(2001)
Eur. J. Cancer
, vol.37
, Issue.7
, pp. 870-877
-
-
Judson, I.1
Radford, J.A.2
Harris, M.3
-
17
-
-
0029001008
-
High-dose ifosfamide: Circumvention of resistance to standard-dose ifosfamide in advanced soft tissue sarcomas
-
Le Cesne A, Antoine E, Spielmann M et al. High-dose ifosfamide: circumvention of resistance to standard-dose ifosfamide in advanced soft tissue sarcomas. J. Clin. Oncol. 13(7), 1600-1608 (1995).
-
(1995)
J. Clin. Oncol.
, vol.13
, Issue.7
, pp. 1600-1608
-
-
Le Cesne, A.1
Antoine, E.2
Spielmann, M.3
-
18
-
-
81155149886
-
Trabectedin in advanced uterine leiomyosarcomas: A retrospective case series analysis from two reference centers
-
Sanfilippo R, Grosso F, Jones RL et al. Trabectedin in advanced uterine leiomyosarcomas: a retrospective case series analysis from two reference centers. Gynecol. Oncol. 123(3), 553-556 (2011).
-
(2011)
Gynecol. Oncol.
, vol.123
, Issue.3
, pp. 553-556
-
-
Sanfilippo, R.1
Grosso, F.2
Jones, R.L.3
-
19
-
-
77956287630
-
Trabectedin: An emerging therapeutic option in soft tissue sarcoma
-
Blay JY. Trabectedin: an emerging therapeutic option in soft tissue sarcoma. Eur. J. Clin. Med. Oncol. 1(2) (2009).
-
(2009)
Eur. J. Clin. Med. Oncol.
, vol.1
, Issue.2
-
-
Blay, J.Y.1
-
20
-
-
84655170216
-
Activity of trabectedin in desmoplastic small round cell tumor
-
López-González A, Cantos B, Tejerina E, Provencio M. Activity of trabectedin in desmoplastic small round cell tumor. Med. Oncol. 28(Suppl. 1), S644-S646 (2011).
-
(2011)
Med. Oncol.
, vol.28
, Issue.SUPPL. 1
-
-
López-González, A.1
Cantos, B.2
Tejerina, E.3
Provencio, M.4
-
21
-
-
77955228557
-
Response to trabectedin treatment in a highly pretreated patient with an advanced meningeal hemangiopericytoma
-
Martinez-Trufero J, Alfaro J, Felipo F, Alvarez M, Madani J, Cebollero A. Response to trabectedin treatment in a highly pretreated patient with an advanced meningeal hemangiopericytoma. Anticancer Drugs 21(8), 795-798 (2010).
-
(2010)
Anticancer Drugs
, vol.21
, Issue.8
, pp. 795-798
-
-
Martinez-Trufero, J.1
Alfaro, J.2
Felipo, F.3
Alvarez, M.4
Madani, J.5
Cebollero, A.6
-
22
-
-
79960983277
-
Efficacy of trabectedin in metastatic solitary fibrous tumor
-
Chaigneau L, Kalbacher E, Thiery-Vuillemin A et al. Efficacy of trabectedin in metastatic solitary fibrous tumor. Rare Tumors 3(3), e29 (2011).
-
(2011)
Rare Tumors
, vol.3
, Issue.3
-
-
Chaigneau, L.1
Kalbacher, E.2
Thiery-Vuillemin, A.3
-
23
-
-
84867579960
-
A retrospective analysis of antitumour activity with trabectedin in translocationrelated sarcomas
-
Le Cesne AL, Cresta S, Maki RG et al. A retrospective analysis of antitumour activity with trabectedin in translocationrelated sarcomas. Eur. J. Cancer 48(16), 3036-3044 (2012).
-
(2012)
Eur. J. Cancer
, vol.48
, Issue.16
, pp. 3036-3044
-
-
Le Cesne, A.L.1
Cresta, S.2
Maki, R.G.3
-
24
-
-
84857530639
-
Phase II clinical trial of neoadjuvant trabectedin in patients with advanced localized myxoid liposarcoma
-
Gronchi A, Bui BN, Bonvalot S et al. Phase II clinical trial of neoadjuvant trabectedin in patients with advanced localized myxoid liposarcoma. Ann. Oncol. 23(3), 771-776 (2012).
-
(2012)
Ann. Oncol.
, vol.23
, Issue.3
, pp. 771-776
-
-
Gronchi, A.1
Bui, B.N.2
Bonvalot, S.3
-
25
-
-
84877246705
-
Trabectedin (T) in advanced, pre-treated synovial sarcoma (SS): A retrospective analysis of 61 patients from four European institutions and from the Italian Rare Cancer Network
-
Prague, Czech Republic, 14-17 November 2012
-
Sanfilippo R, Dileo P, Blay JY et al. Trabectedin (T) in advanced, pre-treated synovial sarcoma (SS): a retrospective analysis of 61 patients from four European institutions and from the Italian Rare Cancer Network. Presented at: 17th Annual Meeting of the Connective Tissue Oncology Society. Prague, Czech Republic, 14-17 November 2012.
-
17th Annual Meeting of the Connective Tissue Oncology Society
-
-
Sanfilippo, R.1
Dileo, P.2
Blay, J.Y.3
-
26
-
-
84878730984
-
Trabectedin in soft tissue sarcomas (STS) carrying a chromosomal translocation: An exploratory analysis
-
Seattle, WA, USA, 1-3 November 2007 (Abstract 900)
-
Grosso F, Jones RL, Blay JY et al. Trabectedin in soft tissue sarcomas (STS) carrying a chromosomal translocation: an exploratory analysis. Presented at: 13th Annual Meeting of the Connective Tissue Oncology Society. Seattle, WA, USA, 1-3 November 2007 (Abstract 900).
-
13th Annual Meeting of the Connective Tissue Oncology Society
-
-
Grosso, F.1
Jones, R.L.2
Blay, J.Y.3
-
27
-
-
84877308031
-
Randomized multicenter Phase III trial of trabectedin (T) versus doxorubicin-based chemotherapy as first-line therapy in patients with translocation-related sarcoma (TRS)
-
Abstract TPS10101
-
Blay JY, Leahy MG, Bui BN et al. Randomized multicenter Phase III trial of trabectedin (T) versus doxorubicin-based chemotherapy as first-line therapy in patients with translocation-related sarcoma (TRS). J. Clin. Oncol. 30(Suppl.), Abstract TPS10101 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.SUPPL.
-
-
Blay, J.Y.1
Leahy, M.G.2
Bui, B.N.3
-
28
-
-
24944460785
-
Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: Multicenter Phase II and pharmacokinetic study
-
Garcia-Carbonero R, Supko JG, Maki RG et al. Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: multicenter Phase II and pharmacokinetic study. J. Clin. Oncol. 23(24), 5484-5492 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.24
, pp. 5484-5492
-
-
Garcia-Carbonero, R.1
Supko, J.G.2
Maki, R.G.3
-
29
-
-
58149186082
-
Phase i combination study of trabectedin and doxorubicin in patients with soft tissue sarcoma
-
Blay JY, von Mehren M, Samuels BL et al. Phase I combination study of trabectedin and doxorubicin in patients with soft tissue sarcoma. Clin. Cancer Res. 14(20), 6656-6662 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, Issue.20
, pp. 6656-6662
-
-
Blay, J.Y.1
Von Mehren, M.2
Samuels, B.L.3
-
30
-
-
84873261540
-
Long-term outcome and effect of maintenance therapy in patients with advanced sarcoma treated with trabectedin: An analysis of 181 patients of the French ATU compassionate use program
-
Blay JY, Italiano A, Ray-Coquard I et al. Long-term outcome and effect of maintenance therapy in patients with advanced sarcoma treated with trabectedin: an analysis of 181 patients of the French ATU compassionate use program. BMC Cancer 13, 64 (2013).
-
(2013)
BMC Cancer
, vol.13
, pp. 64
-
-
Blay, J.Y.1
Italiano, A.2
Ray-Coquard, I.3
-
31
-
-
84877263756
-
Rechallenge with trabectedin in patients with locally advanced or metastatic soft tissue sarcoma following drug holiday: The experience of the French Sarcoma Group (FSG)
-
Abstract 10062
-
Saada E, Rahal C, Ray-Coquard I et al. Rechallenge with trabectedin in patients with locally advanced or metastatic soft tissue sarcoma following drug holiday: the experience of the French Sarcoma Group (FSG). J. Clin. Oncol. 30(Suppl.), Abstract 10062 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.SUPPL.
-
-
Saada, E.1
Rahal, C.2
Ray-Coquard, I.3
-
34
-
-
84877311310
-
-
Institut de cancérologie Gustave Roussy willejuif
-
Institut de cancérologie Gustave Roussy willejuif. Les essais cliniques à l'IGR. www.igr.fr/index.php?p-m=igrinter&p- a=essai&p-sa=cancer-12
-
Les Essais Cliniques À l'Igr
-
-
|