Impact of antimouse CD52 monoclonal antibody on graft's γσ intraepithelial lymphocytes after orthotopic small bowel transplantation in mice

Transplantation

Volumn 95, Issue 5, 2013, Pages 663-670

  Shen, Bo ^a   Yu, Hong ^a   Hao, Xianhua ^a   Qu, Linlin ^b   Cai, Xiujun ^a   Li, Ning ^c  

^a ZHEJIANG UNIVERSITY   (China)

^b University Medical College   (China)

^c JINLING HOSPITAL   (China)

Author keywords

; Mice; Small intestine; T cell receptor; Transplantation

Indexed keywords

ALEMTUZUMAB; KERATINOCYTE GROWTH FACTOR; MESSENGER RNA; TACROLIMUS; CD52 ANTIGEN; GLYCOPROTEIN; LEUKOCYTE ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; MONOCLONAL ANTIBODY; TUMOR ANTIGEN;

ALLOGRAFT; ALPHA BETA T LYMPHOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; DONOR; DRUG MECHANISM; EPITHELIUM CELL; FLOW CYTOMETRY; GAMMA DELTA T LYMPHOCYTE; GENE EXPRESSION; GRAFT REJECTION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTESTINAL INTRAEPITHELIAL LYMPHOCYTE; INTESTINE GRAFT; INTESTINE INJURY; INTESTINE TRANSPLANTATION; MALE; MOUSE; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE DRUG DOSE; SMALL INTESTINE MUCOSA; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; ALLOTRANSPLANTATION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; LYMPHOCYTE; PATHOLOGY; SMALL INTESTINE; TRANSPLANTATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, NEOPLASM; FIBROBLAST GROWTH FACTOR 7; GLYCOPROTEINS; GRAFT REJECTION; INTESTINAL MUCOSA; INTESTINE, SMALL; LYMPHOCYTES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; TRANSPLANTATION, HOMOLOGOUS;

MLCS; MLOWN;

EID: 84877297321     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e31827e6ab3     Document Type: Article

References (30)

1. Abu-Elmagd KM, Costa G, Bond GJ, et al. Evolution of the immu-nosuppressive strategies for the intestinal and multivisceral recipients with special reference to allograft immunity and achievement of partial tolerance. Transpl Int 2009; 22: 96.
2. Li YX, Li N, Li YS, et al. Preliminary experience with partial tolerance protocol in small bowel transplantation. Zhonghua Yi Xue Za Zhi 2009; 89: 2695.
3. Florescu DF, Islam KM, Grant W, et al. Incidence and outcome of fungal infections in pediatric small bowel transplant recipients. Transpl Infect Dis 2010; 12: 497.
4. Das G, Augustine MM, Das J, et al. An important regulatory role for CD4+CD8 alpha alpha T cells in the intestinal epithelial layer in the prevention of inflammatory bowel disease. Proc Natl Acad Sci U S A 2003; 100: 5324.
5. Kunisawa J, Takahashi I, Kiyono H. Intraepithelial lymphocytes: their shared and divergent immunological behaviors in the small and large intestine. Immunol Rev 2007; 215: 136.
6. Matsumoto S, Nanno M, Watanabe N, et al. Physiological roles of gammadelta T-cell receptor intraepithelial lymphocytes in cyto-proliferation and differentiation of mouse intestinal epithelial cells. Immunology 1999; 97: 18.
7. Boismenu R, Havran WL. Modulation of epithelial cell growth by intraepithelial gamma delta T cells. Science 1994; 266: 1253.
8. Vivas S, Ruiz de Morales JM, Ramos F, et al. Alemtuzumab for refractory celiac disease in a patient at risk for enteropathy-associated T-cell lymphoma. N Engl J Med 2006; 354: 2514.
9. Qu L, Li Q, Jiang H, et al. Effect of anti-mouse CD52 monoclonal antibody on mouse intestinal intraepithelial lymphocytes. Transplantation 2009; 88: 766.
10. Cicalese L, Nussler NC, Hoffman RA, et al. Phenotypic and functional characteristics of intestinal intraepithelial lymphocytes during acute rejection of small intestinal allografts. Transpl Int 1998; 11: 102.
11. Yang H, Antony PA, Wildhaber BE, et al. Intestinal intraepithelial lymphocyte gamma deltaYT cellYderived keratinocyte growth factor modulates epithelial growth in the mouse. J Immunol 2004; 172: 4151.
12. Chen Y, Chou K, Fuchs E, et al. Protection of the intestinal mucosa by intraepithelial gamma delta T cells. Proc Natl Acad Sci U S A 2002; 99: 14338.
13. Uchida J, Hamaguchi Y, Oliver JA, et al. The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptorYdependent mechanisms during anti-CD20 antibody immunotherapy. J Exp Med 2004; 199: 1659.
14. Mathew JM, Defaria W, Kato T, et al. Abrogation of the alloreactive responses of cadaveric donor intestinal lymphocytes by intraoperative Campath-1H exposure. Transplant Proc 2005; 37: 1375.
15. Hayday AC. [gamma][delta] cells: a right time and a right place for a conserved third way of protection. Annu Rev Immunol 2000; 18: 975.
16. Hayday A, Theodoridis E, Ramsburg E, et al. Intraepithelial lymphocytes: exploring the Third Way in immunology. Nat Immunol 2001; 2: 997.
17. Chennupati V, Worbs T, Liu X, et al. Intra-and intercompartmental movement of gammadelta T cells: intestinal intraepithelial and peripheral gammadelta T cells represent exclusive nonoverlapping populations with distinct migration characteristics. J Immunol 2010; 185: 5160.
18. Lamb LS Jr, Musk P, Ye Z, et al. Human gammadelta(+) T lymphocytes have in vitro graft vs leukemia activity in the absence of an allogeneic response. Bone Marrow Transplant 2001; 27: 601.
19. Newell KA, He G, Hart J, et al. Treatment with either anti-CD4 or anti-CD8 monoclonal antibodies blocks alphabeta T cell-mediated rejection of intestinal allografts in mice. Transplantation 1997; 64: 959.
20. Sullivan B, Cohen Z, Fu XM, et al. Graft-infiltrating cells in rats receiving orthotopic semiallogeneic small intestine transplantation with portal or systemic venous drainage. Transplantation 1996; 62: 715.
21. Okabe K, Yamaguchi Y, Takai E, et al. CD45RC gammadelta T-cell infiltration is associated with immunologic unresponsiveness induced by prior donor-specific blood transfusion in rat hepatic allografts. Hepatology 2001; 33: 877.
22. Zhou J, Appleton SE, Stadnyk A, et al. CD8+ gammadelta Tregulatory cells mediate kidney allograft prolongation after oral exposure to al-loantigen. Transpl Int 2008; 21: 679.
23. Itoh S, Nakae S, Axtell RC, et al. IL-17 contributes to the development of chronic rejection in a murine heart transplant model. J Clin Immunol 2010; 30: 235.
24. Nikolic B, Cooke DT, Zhao G, et al. Both gamma delta T cells and NK cells inhibit the engraftment of xenogeneic rat bone marrow cells and the induction of xenograft tolerance in mice. J Immunol 2001; 166: 1398.
25. Kirk AD, Ibrahim S, Dawson DV, et al. Characterization of T cells expressing the gamma/delta antigen receptor in human renal allo-grafts. Hum Immunol 1993; 36: 11.
26. Quijano Y, Eiras P, Redondo C, et al. Origin and immunophenotype of intestinal intraepithelial lymphocytes in experimental long-surviving small bowel allografts. Transplant Proc 2002; 34: 221.
27. Oberhuber G, Schmid T, Thaler W, et al. Increase in intraepithelial lymphocytes as an early marker of rejection in a fully allogeneic rat small bowel transplantation model. Eur Surg Res 1993; 25: 310.
28. Kimura T, Hasegawa T, Nakai H, et al. FTY720 reduces T-cell recruitment into murine intestinal allograft and prevents activation of graft-infiltrating cells. Transplantation 2003; 75: 1469.
29. Shen B, Cao S, Shan T, et al. Intensive fluid therapy combined with epinephrine improves orthotopic small bowel transplantation in mice. J Surg Res 2011; 171: 833.
30. Yan S, Rodriguez-Barbosa JI, Pabst O, et al. Protection of mouse small bowel allografts by FTY720 and costimulation blockade. Transplantation 2005; 79: 1703.