Human immunodeficiency virus drug development assisted with AlGaN/GaN high electron mobility transistors and binding-site models

Applied Physics Letters

Volumn 102, Issue 17, 2013, Pages

  Kang, Yen Wen ^a   Lee, Geng Yen ^b   Chyi, Jen Inn ^b   Hsu, Chen Pin ^a   Hsu, You Ren ^a   Hsu, Chia Hsien ^c   Huang, Yu Fen ^a   Sun, Yuh Chang ^a   Chen, Chih Chen ^a   Chun Hung, Sheng ^b   Ren, Fan ^d   Andrew Yeh, J ^a   Wang, Yu Lin ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NATIONAL CENTRAL UNIVERSITY   (Taiwan)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^d J Crayton Pruitt Family Department of Biomedical Engineering   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGAN/GAN HEMTS; ALGAN/GAN HIGH ELECTRON MOBILITY TRANSISTORS; ALGAN/GAN HIGHELECTRON-MOBILITY TRANSISTORS (HEMTS); DISSOCIATION CONSTANT; DRUG DEVELOPMENT; EFAVIRENZ; HUMAN IMMUNODEFICIENCY VIRUS; REVERSE TRANSCRIPTASES;

BINDING SITES; DISEASES; DISSOCIATION; DRUG PRODUCTS; GALLIUM NITRIDE; VIRUSES;

HIGH ELECTRON MOBILITY TRANSISTORS;

EID: 84877259626     PISSN: 00036951     EISSN: None     Source Type: Journal    
DOI: 10.1063/1.4803916     Document Type: Article

References (28)

1. D. G. Prajapati, R. Ramajayam, M. R. Yadav, and R. Giridhar, Bioorg. Med. Chem. 17 (16), 5744 (2009). 10.1016/j.bmc.2009.06.060
2. S. G. Sarafianos, K. Das, S. H. Hughes, and E. Arnold, Curr. Opin. Struct. Biol. 14 (6), 716 (2004). 10.1016/j.sbi.2004.10.013
3. J. Ren, J. Milton, K. L. Weaver, S. A. Short, D. I. Stuart, and D. K. Stammers, Structure 8 (10), 1089 (2000). 10.1016/S0969-2126(00)00513-X
4. M. Gochin, R. Savage, S. Hinckley, and L. F. Cai, Biol. Chem. 387 (4), 477 (2006) 10.1515/BC.2006.063.
5. P. R. Morrill, R. B. Millington, and C. R. Lowe, J. Chromatogr., B: Biomed. Sci. Appl. 793 (2), 229 (2003) 10.1016/S1570-0232(03)00282-4.
6. M. Geitmann, T. Unge, and U. H. Danielson, J. Med. Chem. 49 (8), 2375 (2006). 10.1021/jm0504050
7. C. Bertucci and S. Cimitan, J. Pharm. Biomed. Anal. 32 (4-5), 707 (2003). 10.1016/S0731-7085(03)00178-X
8. Y. Chen, H. Vedala, G. P. Kotchey, A. Audfray, S. Cecioni, A. Imberty, S. Vidal, and A. Star, ACS Nano 6 (1), 760 (2011) 10.1021/nn2042384;
9. W. U. Wang, C. Chen, K. Lin, Y. Fang, and C. M. Lieber, Proc. Natl. Acad. Sci. U.S.A. 102 (9), 3208 (2005). 10.1073/pnas.0406368102
10. T. W. Lin, P. J. Hsieh, C. L. Lin, Y. Y. Fang, J. X. Yang, C. C. Tsai, P. L. Chiang, C. Y. Pan, and Y. T. Chen, Proc. Natl. Acad. Sci. U.S.A. 107 (3), 1047 (2010); 10.1073/pnas.0910243107
11. M. Dragusanu, B.-A. Petre, S. Slamnoiu, C. Vlad, T. Tu, and M. Przybylski, J. Am. Soc. Mass Spectrom. 21 (10), 1643 (2010); 10.1016/j.jasms.2010.06.011
12. Y. Liu, X. Tang, F. Liu, and K. Li, Anal. Chem. 77 (13), 4248 (2005); 10.1021/ac050026e
13. K. Mitsakakis and E. Gizeli, Biosens. Bioelectron. 26 (11), 4579 (2011); 10.1016/j.bios.2011.05.030
14. K. H. Chen, H. W. Wang, B. S. Kang, C. Y. Chang, Y. L. Wang, T. P. Lele, F. Ren, S. J. Pearton, A. Dabiran, A. Osinsky, and P. P. Chow, Sens. Actuators B: Chem. 134 (2), 386 (2008); 10.1016/j.snb.2008.05.012
15. Y. L. Wang, B. H. Chu, K. H. Chen, C. Y. Chang, T. P. Lele, Y. Tseng, S. J. Pearton, J. Ramage, D. Hooten, A. Dabiran, P. P. Chow, and F. Ren, Appl. Phys. Lett. 93 (26), 262101 (2008); 10.1063/1.3056612
16. X. Yu, C. Li, Z. Low, J. Lin, T. J. Anderson, H. T. Wang, F. Ren, Y. L. Wang, C. Y. Chang, S. J. Pearton, C.-H. Hsu, A. Osinsky, A. M. Dabiran, P. Chow, C. Balaban, and J. Painter, ECS Trans. 16 (7), 127 (2008); 10.1149/1.2983168
17. B. S. Kang, H. T. Wang, F. Ren, S. J. Pearton, T. E. Morey, D. M. Dennis, J. W. Johnson, P. Rajagopal, J. C. Roberts, E. L. Piner, and K. J. Linthicum, Appl. Phys. Lett. 91 (25), 252103 (2007). 10.1063/1.2825574
18. S. J. Pearton, F. Ren, Y.-L. Wang, B. H. Chu, K. H. Chen, C. Y. Chang, W. Lim, J. Lin, and D. P. Norton, Prog. Mater. Sci. 55 (1), 1 (2010). 10.1016/j.pmatsci.2009.08.003
19. K. H. Chen, B. S. Kang, H. T. Wang, T. P. Lele, F. Ren, Y. L. Wang, C. Y. Chang, S. J. Pearton, D. M. Dennis, J. W. Johnson, P. Rajagopal, J. C. Roberts, E. L. Piner, and K. J. Linthicum, Appl. Phys. Lett. 92 (19), 192103 (2008); 10.1063/1.2926656
20. B. H. Chu, B. S. Kang, F. Ren, C. Y. Chang, Y. L. Wang, S. J. Pearton, A. V. Glushakov, D. M. Dennis, J. W. Johnson, P. Rajagopal, J. C. Roberts, E. L. Piner, and K. J. Linthicum, Appl. Phys. Lett. 93 (4), 042114 (2008); 10.1063/1.2966158
21. B. S. Kang, F. Ren, L. Wang, C. Lofton, W. H. W. Tan, S. J. Pearton, A. Dabiran, A. Osinsky, and P. P. Chow, Appl. Phys. Lett. 87 (2), 023508 (2005); 10.1063/1.1994951
22. Y. L. Wang, B. H. Chu, K. H. Chen, C. Y. Chang, T. P. Lele, G. Papadi, J. K. Coleman, B. J. Sheppard, C. F. Dungen, S. J. Pearton, J. W. Johnson, P. Rajagopal, J. C. Roberts, E. L. Piner, K. J. Linthicum, and F. Ren, Appl. Phys. Lett. 94 (24), 243901 (2009). 10.1063/1.3153130
23. G. N. Nikolenko, K. A. Delviks-Frankenberry, and V. K. Pathak, J. Virol. 84 (10), 5238 (2010). 10.1128/JVI.01545-09
24. S. D. Young, S. F. Britcher, L. O. Tran, L. S. Payne, W. C. Lumma, T. A. Lyle, J. R. Huff, P. S. Anderson, D. B. Olsen, and S. S. Carroll, Antimicrob. Agents Chemother. 39 (12), 2602 (1995). 10.1128/AAC.39.12.2602
25. Q. Xia, J. Radzio, K. S. Anderson, and N. Sluis-Cremer, Protein Sci. 16 (8), 1728 (2007). 10.1110/ps.072829007
26. S. A. Clark, N. S. Shulman, R. J. Bosch, and J. W. Mellors, AIDS 20 (7), 981 (2006). 10.1097/01.aids.0000222069.14878.44
27. P. Decha, P. Intharathep, T. Udommaneethanakit, P. Sompornpisut, S. Hannongbua, P. Wolschann, and V. Parasuk, J. Enzyme Inhib. Med. Chem. 26 (1), 29 (2011). 10.3109/14756360903563393
28. See supplementary material at http://dx.doi.org/10.1063/1.4803916 E-APPLAB-102-005319 for leveling the real-time current in Figure.