Endometriosis: An update on management

Women's Health

Volumn 9, Issue 3, 2013, Pages 233-250

  Bernardi, Lia A ^a   Pavone, Mary Ellen ^b  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

dysmenorrhea; dyspareunia; endometrioma; endometriosis; infertility; IVF; medical treatment; pelvic pain; surgery

Indexed keywords

AROMATASE INHIBITOR; BUSERELIN; CLOMIFENE CITRATE; DANAZOL; ESTRADIOL; ESTROGEN; GESTAGEN; GESTRINONE; GONADORELIN AGONIST; GOSERELIN; LEUPRORELIN; LEVONORGESTREL; MEDROXYPROGESTERONE ACETATE; NAFARELIN; NORETHISTERONE ACETATE; ORAL CONTRACEPTIVE AGENT; PENTOXIFYLLINE; PLACEBO; TRIPTORELIN; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ANALGESIA; BLEEDING; BLOATING; BREAST TENDERNESS; CYSTECTOMY; DISEASE ASSOCIATION; DRUG INDUCED HEADACHE; DYSMENORRHEA; ENDOMETRIOSIS; FEMALE INFERTILITY; FERTILIZATION IN VITRO; FLUID RETENTION; HUMAN; INTRAUTERINE INSEMINATION; LAPAROSCOPY; LASER SURGERY; MOOD CHANGE; NAUSEA; OUTCOME ASSESSMENT; PAIN; PAIN ASSESSMENT; PATIENT SATISFACTION; PELVIS PAIN SYNDROME; REVIEW; SIDE EFFECT; WEIGHT GAIN;

HUMANS; IMMUNIZATION PROGRAMS; POPULATION SURVEILLANCE;

EID: 84877257534     PISSN: 17455057     EISSN: 17455065     Source Type: Journal    
DOI: 10.2217/whe.13.24     Document Type: Review

References (75)

1. Giudice LC, Kao LC. Endometriosis. Lancet 364(9447), 1789-1799 (2004).
2. Bulun SE. Endometriosis. N. Engl. J. Med. 360(3), 268-279 (2009).
3. Practice bulletin no. 114: management of endometriosis. Obstet. Gynecol. 116(1), 223-236 (2010).
4. Falcone T, Lebovic DI. Clinical management of endometriosis. Obstet. Gynecol. 118(3), 691-705 (2011).
5. Fritz MA, Speroff L. Endometriosis. In: Clinical Gynecologic Endocrinology and Infertility (8th Edition). Lippincott Williams and Wilkins, PA, USA, 1221-1248 (2011).
6. Practice Committee of American Society for Reproductive Medicine. Treatment of pelvic pain associated with endometriosis. Fertil. Steril. 90(Suppl. 5), S260-S269 (2008).
7. Giudice LC. Clinical practice. Endometriosis. N. Engl. J. Med. 362(25), 2389-2398 (2010).
8. Olive DL. Medical therapy of endometriosis. Semin. Reprod. Med. 21(2), 209-222 (2003).
9. Vierikko P, Kauppila A, Ronnberg L, Vihko R. Steroidal regulation of endometriosis tissue: lack of induction of 17 beta-hydroxysteroid dehydrogenase activity by progesterone, medroxyprogesterone acetate, or danazol. Fertil. Steril. 43(2), 218-224 (1985).
10. Obolensky W, Kamber J. Therapy of endometriosis with dydrogesterone (Duphaston Depot) in delayed-action preparation form. Ther. Umsch. 30(7), 558-561 (1973).
11. Schweppe KW, Wynn RM. Ultrastructural changes in endometriotic implants during the menstrual cycle. Obstet. Gynecol. 58(4), 465-473 (1981).
12. Vercellini P, Trespidi L, Colombo A, Vendola N, Marchini M, Crosignani PG. A gonadotropin-releasing hormone agonist versus a low-dose oral contraceptive for pelvic pain associated with endometriosis. Fertil. Steril. 60(1), 75-79 (1993).
13. Harada T, Momoeda M, Taketani Y, Hoshiai H, Terakawa N. Low-dose oral contraceptive pill for dysmenorrhea associated with endometriosis: a placebo-controlled, double-blind, randomized trial. Fertil. Steril. 90(5), 1583-1588 (2008).
14. Guzick DS, Huang LS, Broadman BA, Nealon M, Hornstein MD. Randomized trial of leuprolide versus continuous oral contraceptives in the treatment of endometriosis-associated pelvic pain. Fertil. Steril. 95(5), 1568-1573 (2011).
15. Telimaa S, Puolakka J, Ronnberg L, Kauppila A. Placebo-controlled comparison of danazol and high-dose medroxyprogesterone acetate in the treatment of endometriosis. Gynecol. Endocrinol. 1(1), 13-23 (1987).
16. Harrison RF, Barry-Kinsella C. Efficacy of medroxyprogesterone treatment in infertile women with endometriosis: a prospective, randomized, placebo-controlled study. Fertil. Steril. 74(1), 24-30 (2000).
17. Vercellini P, De Giorgi O, Oldani S, Cortesi I, Panazza S, Crosignani PG. Depot medroxyprogesterone acetate versus an oral contraceptive combined with very-low-dose danazol for long-term treatment of pelvic pain associated with endometriosis. Am. J. Obstet. Gynecol. 175(2), 396-401 (1996).
18. Schlaff WD, Carson SA, Luciano A, Ross D, Bergqvist A. Subcutaneous injection of depot medroxyprogesterone acetate compared with leuprolide acetate in the treatment of endometriosis-associated pain. Fertil. Steril. 85(2), 314-325 (2006).
19. Vercellini P, Frontino G, De Giorgi O, Aimi G, Zaina B, Crosignani PG. Comparison of a levonorgestrel-releasing intrauterine device versus expectant management after conservative surgery for symptomatic endometriosis: a pilot study. Fertil. Steril. 80(2), 305-309 (2003).
20. Petta CA, Ferriani RA, Abrao MS et al. Randomized clinical trial of a levonorgestrel-releasing intrauterine system and a depot GnRH analogue for the treatment of chronic pelvic pain in women with endometriosis. Hum. Reprod. 20(7), 1993-1998 (2005).
21. Wong AY, Tang LC, Chin RK. Levonorgestrel-releasing intrauterine system (Mirena) and Depot medroxyprogesterone acetate (Depoprovera) as long-term maintenance therapy for patients with moderate and severe endometriosis: a randomised controlled trial. Aust. NZ J. Obstet. Gynaecol. 50(3), 273-279 (2010).
22. Tanmahasamut P, Rattanachaiyanont M, Angsuwathana S, Techatraisak K, Indhavivadhana S, Leerasiri P. Postoperative levonorgestrel-releasing intrauterine system for pelvic endometriosis-related pain: a randomized controlled trial. Obstet. Gynecol. 119(3), 519-526 (2012).
23. Vercellini P, Cortesi I, Crosignani PG. Progestins for symptomatic endometriosis: a critical analysis of the evidence. Fertil. Steril. 68(3), 393-401 (1997).
24. Brown J, Pan A, Hart RJ. Gonadotrophin-releasing hormone analogues for pain associated with endometriosis. Cochrane Database Syst. Rev. 12, CD008475 (2010).
25. Barbieri RL. Hormone treatment of endometriosis: the estrogen threshold hypothesis. Am. J. Obstet. Gynecol. 166(2), 740-745 (1992).
26. Hornstein MD, Surrey ES, Weisberg GW, Casino LA. Leuprolide acetate depot and hormonal add-back in endometriosis: a 12-month study. Lupron Add-Back Study Group. Obstet. Gynecol. 91(1), 16-24 (1998).
27. Surrey ES, Hornstein MD. Prolonged GnRH agonist and add-back therapy for symptomatic endometriosis: long-term follow-up. Obstet. Gynecol. 99(5 Pt 1), 709-719 (2002).
28. Farquhar C, Prentice A, Singla AA, Selak V. Danazol for pelvic pain associated with endometriosis. Cochrane Database Syst. Rev. 4, CD000068 (2007).
29. Attar E, Bulun SE. Aromatase inhibitors: the next generation of therapeutics for endometriosis? Fertil. Steril. 85(5), 1307-1318 (2006).
30. Pavone ME, Bulun SE. Aromatase inhibitors for the treatment of endometriosis. Fertil. Steril. 98(6), 1370-1379 (2012).
31. Ailawadi RK, Jobanputra S, Kataria M, Gurates B, Bulun SE. Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study. Fertil. Steril. 81(2), 290-296 (2004).
32. Soysal S, Soysal ME, Ozer S, Gul N, Gezgin T. The effects of post-surgical administration of goserelin plus anastrozole compared to goserelin alone in patients with severe endometriosis: a prospective randomized trial. Hum. Reprod. 19(1), 160-167 (2004).
33. Amsterdam LL, Gentry W, Jobanputra S, Wolf M, Rubin SD, Bulun SE. Anastrazole and oral contraceptives: a novel treatment for endometriosis. Fertil. Steril. 84(2), 300-304 (2005).
34. Badawy A, Shokeir T, Allam AF, Abdelhady H. Pregnancy outcome after ovulation induction with aromatase inhibitors or clomiphene citrate in unexplained infertility. Acta. Obstet. Gynecol. Scand. 88(2), 187-191 (2009).
35. Kamencic H, Thiel JA. Pentoxifylline after conservative surgery for endometriosis: a randomized, controlled trial. J. Minim. Invasive Gynecol. 15(1), 62-66 (2008).
36. Alborzi S, Ghotbi S, Parsanezhad ME, Dehbashi S, Alborzi S, Alborzi M. Pentoxifylline therapy after laparoscopic surgery for different stages of endometriosis: a prospective, double-blind, randomized, placebo-controlled study. J. Minim. Invasive Gynecol. 14(1), 54-58 (2007).
37. Koninckx PR, Craessaerts M, Timmerman D, Cornillie F, Kennedy S. Anti-TNF-alpha treatment for deep endometriosis-associated pain: a randomized placebo-controlled trial. Hum. Reprod. 23(9), 2017-2023 (2008).
38. Sutton CJ, Ewen SP, Whitelaw N, Haines P. Prospective, randomized, double-blind, controlled trial of laser laparoscopy in the treatment of pelvic pain associated with minimal, mild, and moderate endometriosis. Fertil. Steril. 62(4), 696-700 (1994).
39. Sutton CJ, Pooley AS, Ewen SP, Haines P. Follow-up report on a randomized controlled trial of laser laparoscopy in the treatment of pelvic pain associated with minimal to moderate endometriosis. Fertil. Steril. 68(6), 1070-1074 (1997).
40. Jones KD, Haines P, Sutton CJ. Long-term follow-up of a controlled trial of laser laparoscopy for pelvic pain. JSLS 5(2), 111-115 (2001).
41. Jacobson TZ, Duffy JM, Barlow D, Koninckx PR, Garry R. Laparoscopic surgery for pelvic pain associated with endometriosis. Cochrane Database Syst. Rev. 4, CD001300 (2009).
42. Healey M, Ang WC, Cheng C. Surgical treatment of endometriosis: a prospective randomized double-blinded trial comparing excision and ablation. Fertil. Steril. 94(7), 2536-2540 (2010).
43. Furness S, Yap C, Farquhar C, Cheong YC. Pre and post operative medical therapy for endometriosis surgery. Cochrane Database Syst. Rev. 3, CD003678 (2004).
44. Beretta P, Franchi M, Ghezzi F, Busacca M, Zupi E, Bolis P. Randomized clinical trial of two laparoscopic treatments of endometriomas: cystectomy versus drainage and coagulation. Fertil. Steril. 70(6), 1176-1180 (1998).
45. Alborzi S, Momtahan M, Parsanezhad ME, Dehbashi S, Zolghadri J, Alborzi S. A prospective, randomized study comparing laparoscopic ovarian cystectomy versus fenestration and coagulation in patients with endometriomas. Fertil. Steril. 82(6), 1633-1637 (2004).
46. Chapron C, Chopin N, Borghese B, Malartic C, Decuypere F, Foulot H. Surgical management of deeply infiltrating endometriosis: an update. Ann. NY Acad. Sci. 1034, 326-337 (2004).
47. Roman H, Vassilieff M, Gourcerol G et al. Surgical management of deep infiltrating endometriosis of the rectum: pleading for a symptom-guided approach. Hum. Reprod. 26(2), 274-281 (2011).
48. D'Hooghe TM, Debrock S, Hill JA, Meuleman C. Endometriosis and subfertility: is the relationship resolved? Semin. Reprod. Med. 21(2), 243-254 (2003).
49. Hughes E, Brown J, Collins JJ, Farquhar C, Fedorkow DM, Vandekerckhove P. Ovulation suppression for endometriosis. Cochrane Database Syst. Rev. 3, CD000155 (2007).
50. Practice Committee of the American Society for Reproductive Medicine. Endometriosis and infertility: a committee opinion. Fertil. Steril. 98(3), 591-598 (2012).
51. Deaton JL, Gibson M, Blackmer KM, Nakajima ST, Badger GJ, Brumsted Jr. A randomized, controlled trial of clomiphene citrate and intrauterine insemination in couples with unexplained infertility or surgically corrected endometriosis. Fertil. Steril. 54(6), 1083-1088 (1990).
52. Tummon IS, Asher LJ, Martin JS, Tulandi T. Randomized controlled trial of superovulation and insemination for infertility associated with minimal or mild endometriosis. Fertil. Steril. 68(1), 8-12 (1997).
53. Guzick DS, Carson SA, Coutifaris C et al. Efficacy of superovulation and intrauterine insemination in the treatment of infertility. National Cooperative Reproductive Medicine Network. N. Engl. J. Med. 340(3), 177-183 (1999).
54. Barnhart K, Dunsmoor-Su R, Coutifaris C. Effect of endometriosis on in vitro fertilization. Fertil. Steril. 77(6), 1148-1155 (2002).
55. Sallam HN, Garcia-Velasco JA, Dias S, Arici A. Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis. Cochrane Database Syst. Rev. 1, CD004635 (2006).
56. Littman E, Giudice L, Lathi R, Berker B, Milki A, Nezhat C. Role of laparoscopic treatment of endometriosis in patients with failed in vitro fertilization cycles. Fertil. Steril. 84(6), 1574-1578 (2005).
57. Marcoux S, Maheux R, Berube S. Laparoscopic surgery in infertile women with minimal or mild endometriosis. Canadian Collaborative Group on Endometriosis. N. Engl. J. Med. 337(4), 217-222 (1997).
58. Parazzini F. Ablation of lesions or no treatment in minimal-mild endometriosis in infertile women: a randomized trial. Gruppo Italiano per lo Studio dell'Endometriosi. Hum. Reprod. 14(5), 1332-1334 (1999).
59. Jacobson TZ, Duffy JM, Barlow D, Farquhar C, Koninckx PR, Olive D. Laparoscopic surgery for subfertility associated with endometriosis. Cochrane Database Syst. Rev. 1, CD001398 (2010).
60. Crosignani PG, Vercellini P, Biffignandi F, Costantini W, Cortesi I, Imparato E. Laparoscopy versus laparotomy in conservative surgical treatment for severe endometriosis. Fertil. Steril. 66(5), 706-711 (1996).
61. Decherney AH. Endometriosis: recurrence and retreatment. Clin. Ther. 14(6), 766-772; discussion 765 (1992).
62. Guo SW. Recurrence of endometriosis and its control. Hum. Reprod. Update 15(4), 441-461 (2009).
63. Vercellini P, Somigliana E, Vigano P, De Matteis S, Barbara G, Fedele L. The effect of second-line surgery on reproductive performance of women with recurrent endometriosis: a systematic review. Acta Obstet. Gynecol. Scand. 88(10), 1074-1082 (2009).
64. Tsoumpou I, Kyrgiou M, Gelbaya TA, Nardo LG. The effect of surgical treatment for endometrioma on in vitro fertilization outcomes: a systematic review and meta-analysis. Fertil. Steril. 92(1), 75-87 (2009).
65. Koch J, Rowan K, Rombauts L, Yazdani A, Chapman M, Johnson N. Endometriosis and infertility - a consensus statement from ACCEPT (Australasian CREI Consensus Expert Panel on Trial evidence). Aust. N Z J. Obstet. Gynecol. 52(6), 513-522 (2012).
66. Somigliana E, Infantino M, Benedetti F, Arnoldi M, Calanna G, Ragni G. The presence of ovarian endometriomas is associated with a reduced responsiveness to gonadotropins. Fertil. Steril. 86(1), 192-196 (2006).
67. Almog B, Shehata F, Sheizaf B, Tan SL, Tulandi T. Effects of ovarian endometrioma on the number of oocytes retrieved for in vitro fertilization. Fertil. Steril. 95(2), 525-527 (2011).
68. Benaglia L, Pasin R, Somigliana E, Vercellini P, Ragni G, Fedele L. Unoperated ovarian endometriomas and responsiveness to hyperstimulation. Hum. Reprod. 26(6), 1356-1361 (2011).
69. Benschop L, Farquhar C, van der Poel N, Heineman MJ. Interventions for women with endometrioma prior to assisted reproductive technology. Cochrane Database Syst. Rev. 11, CD008571 (2010).
70. Somigliana E, Arnoldi M, Benaglia L, Iemmello R, Nicolosi AE, Ragni G. IVF-ICSI outcome in women operated on for bilateral endometriomas. Hum. Reprod. 23(7), 1526-1530 (2008).
71. Tsolakidis D, Pados G, Vavilis D et al. The impact on ovarian reserve after laparoscopic ovarian cystectomy versus three-stage management in patients with endometriomas: a prospective randomized study. Fertil. Steril. 94(1), 71-77 (2010).
72. Somigliana E, Berlanda N, Benaglia L, Vigano P, Vercellini P, Fedele L. Surgical excision of endometriomas and ovarian reserve: a systematic review on serum antimullerian hormone level modifications. Fertil. Steril. 98(6), 1531-1538 (2012).
73. Raffi F, Metwally M, Amer S. The impact of excision of ovarian endometrioma on ovarian reserve: a systematic review and meta-analysis. J. Clin. Endocrinol. Metab. 97(9), 3146-3154 (2012).
74. CDC. US medical eligibility criteria for contraceptive use. www.cdc.gov/mmwr/pdf/rr/rr59e0528.pdf (Accessed 19 February 2013
75. Society for Assisted Reproductive Technology. National data summary from 2011. www.sart.org (Accessed 8 February 2013