Thyroglobulin in smoking mothers and their newborns at delivery suggests autoregulation of placental iodide transport overcoming thiocyanate inhibition

European Journal of Endocrinology

Volumn 168, Issue 5, 2013, Pages 723-731

  Andersen, Stine L ^a   Nøhr, Susanne B ^a   Wu, Chun S ^b   Olsen, Jørn ^b   Pedersen, Klaus M ^c   Laurberg, Peter ^a  

^a AALBORG UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c LILLEBAELT HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

COTININE; IODIDE; THIOCYANATE; THYROGLOBULIN;

ADULT; ARTICLE; AUTOREGULATION; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DELIVERY; DENMARK; DIET SUPPLEMENTATION; FEMALE; HUMAN; IODINE DEFICIENCY; MAJOR CLINICAL STUDY; MATERNAL BLOOD; MATERNAL SMOKING; NEWBORN; PLACENTAL TRANSFER; PRIORITY JOURNAL; UMBILICAL CORD BLOOD;

ADULT; CROSS-SECTIONAL STUDIES; DELIVERY, OBSTETRIC; DENMARK; FEMALE; FETAL BLOOD; HOMEOSTASIS; HUMANS; INFANT, NEWBORN; IODINE; MALE; MATERNAL-FETAL EXCHANGE; PREGNANCY; SMOKING; THYROGLOBULIN;

EID: 84877151663     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-12-0759     Document Type: Article

References (45)

1. Morreale de Escobar G, Obregon MJ & Escobar del Rey F. Role of thyroid hormone during early brain development. European Journal of Endocrinology 2004 151 U25-U37. (doi:10.1530/eje. 0.151U025)
2. Delange F. The role of iodine in brain development. Proceedings of the Nutrition Society 2000 59 75-79. (doi:10.1017/ S0029665100000094)
3. Burrow GN, Fisher DA & Larsen PR. Maternal and fetal thyroid function. New England Journal of Medicine 1994 331 1072-1078. (doi:10.1056/NEJM199410203311608)
4. Gulaboglu M, Borekci B & Halici Z. Placental tissue iodine level and blood magnesium concentration in pre-eclamptic and normal pregnancy. International Journal of Gynaecology and Obstetrics 2007 98 100-104. (doi:10.1016/j.ijgo.2007.03.047)
5. Burns R, Azizi F, Hedayati M., Mirmiran P, O'Herlihy C & Smyth PP. Is placental iodine content related to dietary iodine intake? Clinical Endocrinology 2011 75 261-264. (doi:10.1111/j.1365-2265. 2011.04039.x)
6. Burns R, O'Herlihy C & Smyth PP. The placenta as a compensatory iodine storage organ. Thyroid 2011 21 541-546. (doi:10.1089/ thy.2010.0203)
7. K symporter and Pendred syndrome genes in trophoblast cells. Journal of Clinical Endocrinology and Metabolism 2000 85 4367-4372. (doi:10.1210/jc.85. 11.4367)
8. Mitchell AM, Manley SW, Morris J.C., Powell KA, Bergert ER & Mortimer RH. Sodium iodide symporter (NIS) gene expression in human placenta. Placenta 2001 22 256-258. (doi:10.1053/plac. 2000.0609)
9. Di Cosmo C., Fanelli G, Tonacchera M., Ferrarini E, Dimida A, Agretti P., De Marco G, Vitti P, Pinchera A, Bevilacqua G et al. The sodium-iodide symporter expression in placental tissue at different gestational age: an immunohistochemical study. Clinical Endocrinology 2006 65 544-548. (doi:10.1111/j.1365-2265.2006. 02577.x)
10. Arturi F, Lacroix L, Presta I., Scarpelli D, Caillou B, Schlumberger M., Russo D, Bidart JM & Filetti S. Regulation by human chorionic gonadotropin of sodium/iodide symporter gene expression in the JAr human choriocarcinoma cell line. Endocrinology 2002 143 2216-2220. (doi:10.1210/en.143.6. 2216)
11. Manley SW, Li H & Mortimer RH. The BeWo choriocarcinoma cell line as a model of iodide transport by placenta. Placenta 2005 26 380-386. (doi:10.1016/j.placenta.2004.07.004)
12. Dohan O, De la Vieja A, Paroder V, Riedel C, Artani M, Reed M, Ginter CS & Carrasco N. The sodium/iodide symporter (NIS): characterization, regulation, and medical significance. Endocrine Reviews 2003 24 48-77. (doi:10.1210/er.2001-0029)
13. Tazebay UH, Wapnir IL, Levy O, Dohan O., Zuckier LS, Zhao QH, Deng HF, Amenta PS, Fineberg S, Pestell RG et al. The mammary gland iodide transporter is expressed during lactation and in breast cancer. Nature Medicine 2000 6 871-878. (doi:10.1038/ 78630)
14. Laurberg P, Nohr SB, Pedersen KM & Fuglsang E. Iodine nutrition in breast-fed infants is impaired by maternal smoking. Journal of Clinical Endocrinology and Metabolism 2004 89 181-187. (doi:10.1210/jc.2003-030829)
15. Spitzweg C, Joba W, Eisenmenger W & Heufelder AE. Analysis of human sodium iodide symporter gene expression in extrathyroidal tissues and cloning of its complementary deoxyribonucleic acids from salivary gland, mammary gland, and gastric mucosa. Journal of Clinical Endocrinology and Metabolism 1998 83 1746-1751. (doi:10.1210/jc.83.5.1746)
16. K symporter mediates active iodide uptake in the intestine. American Journal of Physiology. Cell Physiology 2009 296 C654-C662. (doi:10.1152/ajpcell.00509.2008)
17. C-dependent multivitamin transporter. Archives of Biochemistry and Biophysics 1999 366 95-106. (doi:10.1006/ abbi.1999.1213)
18. C-dependent multivitamin transporter. Cloning, functional expression, gene structure, and chromosomal localization. Journal of Biological Chemistry 1999 274 14875-14883. (doi:10.1074/jbc.274.21.14875)
19. C/multi-vitamin transporter (hSMVT). Journal of Biological Chemistry 2011 286 131-137. (doi:10.1074/jbc. M110.167197)
20. Bidart JM, Mian C, Lazar V., Russo D, Filetti S, Caillou B & Schlumberger M. Expression of pendrin and the Pendred syndrome (PDS) gene in human thyroid tissues. Journal of Clinical Endocrinology and Metabolism 2000 85 2028-2033. (doi:10.1210/jc.85.5.2028)
21. Tonacchera M, Pinchera A, Dimida A., Ferrarini E, Agretti P, Vitti P., Santini F, Crump K & Gibbs J. Relative potencies and additivity of perchlorate, thiocyanate, nitrate, and iodide on the inhibition of radioactive iodide uptake by the human sodium iodide symporter. Thyroid 2004 14 1012-1019. (doi:10.1089/ thy.2004.14.1012)
22. Laurberg P, Pedersen IB, Carle A, Andersen S., Knudsen N & Karmisholt J. The relationship between thiocyanate and iodine. In Comprehensive Handbook of Iodine: Nutritional, Biochemical, Pathological and Therapeutic Aspects, edn 1st, pp 275-281. Eds VR Preedy, GN Burrow & RR Watson, Oxford: Academic Press/Elsevier, 2009.
23. Knudsen N, Bulow I, Laurberg P., Ovesen L, Perrild H & Jorgensen T. Association of tobacco smoking with goiter in a low-iodine-intake area. Archives of Internal Medicine 2002 162 439-443. (doi:10.1001/archinte.162.4.439)
24. Nohr SB, Laurberg P, Borlum K.G., Pedersen KM, Johannesen PL, Damm P, Fuglsang E & Johansen A. Iodine status in neonates in Denmark: regional variations and dependency on maternal iodine supplementation. Acta Paediatrica 1994 83 578-582. (doi:10.1111/j.1651-2227.1994.tb13085.x)
25. Schone F, Leiterer M, Lebzien P., Bemmann D, Spolders M & Flachowsky G. Iodine concentration of milk in a dose-response study with dairy cows and implications for consumer iodine intake. Journal of Trace Elements in Medicine and Biology 2009 23 84-92. (doi:10.1016/j.jtemb.2009.02.004)
26. Leung AM, Braverman LE, He X, Heeren T & Pearce EN. Breastmilk iodine concentrations following acute dietary iodine intake. Thyroid 2012 22 1176-1180. (doi:10.1089/thy.2012. 0294)
27. Pedersen KM, Borlum KG, Knudsen P.R., Hansen ES, Johannesen PL & Laurberg P. Urinary iodine excretion is low and serum thyroglobulin high in pregnant women in parts of Denmark. Acta Obstetricia et Gynecologica Scandinavica 1988 67 413-416. (doi:10.3109/00016348809004251)
28. Vejbjerg P, Knudsen N, Perrild H., Laurberg P, Carle A, Pedersen I.B., Rasmussen LB, Ovesen L & Jorgensen T. Thyroglobulin as a marker of iodine nutrition status in the general population. European Journal of Endocrinology 2009 161 475-481. (doi:10.1530/EJE-09-0262)
29. Knudsen N, Bulow I, Jorgensen T., Perrild H, Ovesen L & Laurberg P. Serum Tg - a sensitive marker of thyroid abnormalities and iodine deficiency in epidemiological studies. Journal of Clinical Endocrinology and Metabolism 2001 86 3599-3603. (doi:10. 1210/jc.86.8.3599)
30. Nohr SB, Laurberg P, Borlum K.G., Pedersen KM, Johannesen PL, Damm P, Fuglsang E & Johansen A. Iodine deficiency in pregnancy in Denmark. Acta Obstetricia et Gynecologica Scandinavica 1993 72 350-353. (doi:10.3109/00016349 309021111)
31. Nohr SB & Laurberg P. Opposite variations in maternal and neonatal thyroid function induced by iodine supplementation during pregnancy. Journal of Clinical Endocrinology and Metabolism 2000 85 623-627. (doi:10.1210/jc.85.2.623)
32. Laurberg P, Jorgensen T, Perrild H., Ovesen L, Knudsen N, Pedersen I.B., Rasmussen LB, Carle A & Vejbjerg P. The Danish investigation on iodine intake and thyroid disease, DanThyr: status and perspectives. European Journal of Endocrinology 2006 155 219-228. (doi:10.1530/eje.1.02210)
33. Degiampietro P, Peheim E, Drew D., Graf H & Colombo JP. Determination of thiocyanate in plasma and saliva without deproteinisation and its validation as a smoking parameter. Journal of Clinical Chemistry and Clinical Biochemistry 1987 25 711-717.
34. Laurberg P. Thyroxine and 3,5, 3'-triiodothyronine content of thyroglobulin in thyroid needle aspirates in hyperthyroidism and hypothyroidism. Journal of Clinical Endocrinology and Metabolism 1987 64 969-974. (doi:10.1210/jcem-64-5-969)
35. Laurberg P & Pedersen KM. Sensitive assay for thyroglobulin autoantibodies in serum employing polyethylene glycol for precipitation. Scandinavian Journal of Clinical and Laboratory Investigation 1988 48 137-140.
36. Spencer CA, Takeuchi M, Kazarosyan M., Wang CC, Guttler RB, Singer PA, Fatemi S, LoPresti JS & Nicoloff JT. Serum thyroglobulin autoantibodies: prevalence, influence on serum thyroglobulin measurement, and prognostic significance in patients with differentiated thyroid carcinoma. Journal of Clinical Endocrinology and Metabolism 1998 83 1121-1127. (doi:10.1210/jc.83. 4.1121)
37. Laurberg P, Pedersen KM, Hreidarsson A, Sigfusson N., Iversen E & Knudsen PR. Iodine intake and the pattern of thyroid disorders: a comparative epidemiological study of thyroid abnormalities in the elderly in Iceland and in Jutland, Denmark. Journal of Clinical Endocrinology and Metabolism 1998 83 765-769. (doi:10.1210/ jc.83.3.765)
38. Laurberg P, Andersen S, Bjarnadottir R.I., Carle A., Hreidarsson A, Knudsen N, Ovesen L., Pedersen I & Rasmussen L. Evaluating iodine deficiency in pregnant women and young infants - complex physiology with a risk of misinterpretation. Public Health Nutrition 2007 10 1547-1552. (doi:10.1017/S136898000 7360898)
39. Schröder-van der Elst JP, van der Heide D, Kastelijn J, Rousset B & Obregon MJ. The expression of the sodium/iodide symporter is up-regulated in the thyroid of fetuses of iodine-deficient rats. Endocrinology 2001 142 3736-3741. (doi:10.1210/en.142. 9.3736)
40. Li H, Richard K, McKinnon B & Mortimer RH. Effect of iodide on human choriogonadotropin, sodium-iodide symporter expression, and iodide uptake in BeWo choriocarcinoma cells. Journal of Clinical Endocrinology and Metabolism 2007 92 4046-4051. (doi:10.1210/jc.2006-2358)
41. Ferretti E, Arturi F, Mattei T., Scipioni A, Tell G, Tosi E., Presta I, Morisi R, Lacroix L, Gulino A et al. Expression, regulation, and function of paired-box gene 8 in the human placenta and placental cancer cell lines. Endocrinology 2005 146 4009-4015. (doi:10.1210/en.2005-0084)
42. Li H, Landers K, Patel J., Richard K & Mortimer RH. Effect of oxygen concentrations on sodium iodide symporter expression and iodide uptake and hCG expression in human choriocarcinoma BeWo cells. American Journal of Physiology. Endocrinology and Metabolism 2011 300 E1085-E1091. (doi:10.1152/ajpendo. 00679.2010)
43. Prasad PD, Ramamoorthy S, Leibach FH & Ganapathy V. Characterization of a sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin and lipoate in human placental choriocarcinoma cells. Placenta 1997 18 527-533. (doi:10.1016/0143-4004(77)90006-6)
44. Egebjerg Jensen K., Jensen A, Nohr B & Kruger Kjaer S. Do pregnant women still smoke? A study of smoking patterns among 261,029 primiparous women in Denmark 1997-2005. Acta Obstetricia et Gynecologica Scandinavica 2008 87 760-767. (doi:10.1080/00016340802179814)
45. Pincus MR, Abraham NZ & Carty RP. Clinical enzymology. In Henry's Clinical Diagnosis and Management by Laboratory Methods, edn 22nd, pp 273-295. Eds RA McPherson & MR Pincus, Philadelphia, PA, USA: Saunders/Elsevier, 2011.