Molecular epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) among veterinary students and personnel at a veterinary hospital in Malaysia

Veterinary Microbiology

Volumn 164, Issue 3-4, 2013, Pages 352-358

  Aklilu, E ^a,b   Zunita, Z ^a   Hassan, L ^a   Cheng, Chen Hui ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

^b UNIVERSITI MALAYSIA KELANTAN   (Malaysia)

Author keywords

MLST; Molecular epidemiology; Pandemic MRSA clones; PFGE; Spa typing; Veterinarians

Indexed keywords

ANTIBIOTIC SENSITIVITY; ARTICLE; DNA FINGERPRINTING; GENE AMPLIFICATION; GENOTYPE; GEOGRAPHY; HUMAN; MALAYSIA; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR EPIDEMIOLOGY; MULTILOCUS SEQUENCE TYPING; NONHUMAN; POLYMERASE CHAIN REACTION; PULSED FIELD GEL ELECTROPHORESIS; VETERINARY MEDICINE;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL TYPING TECHNIQUES; ELECTROPHORESIS, GEL, PULSED-FIELD; GENES, BACTERIAL; HOSPITALS, ANIMAL; MALAYSIA; MEDICAL STAFF; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MOLECULAR EPIDEMIOLOGY; MULTILOCUS SEQUENCE TYPING; PREVALENCE; STAPHYLOCOCCAL INFECTIONS; STUDENTS;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;

EID: 84877148916     PISSN: 03781135     EISSN: 18732542     Source Type: Journal    
DOI: 10.1016/j.vetmic.2013.02.030     Document Type: Article

References (47)

1. Abudu L., Blair I., Fraise A., Cheng K.K. Methicillin-resistant Staphylococcus aureus (MRSA): a community-based prevalence survey. Epidemiol. Infect. 2001, 126:351-356.
2. Aklilu E., Zunita Z., Hassan L., Chen H.C. Phenotypic and genotypic characterization of methicillinresistant Staphylococcus aureus (MRSA) isolated from dogs and cats at University Veterinary Hospital, Universiti Putra Malaysia. Trop. Biomed. 2010, 27:483-492.
3. Anderson M.E.C., Lefebvre S.L., Weese J.S. Evaluation of prevalence and risk factors for methicillin-resistant Staphylococcus aureus colonization in veterinary personnel attending an international equine veterinary conference. Vet. Microbiol. 2008, 129:410-417.
4. Araj G.F., Talhouk R.S., Simaan C.J., Maasad M.J. Discrepancies between mecA PCR and conventional tests used for the detection of methicillin-resistant Staphylococcus aureus. Int. J. Antimicrob. Agents 1999, 11:47-52.
5. Becker A., Forster D.H., Kniehl E. Oxacillin resistance screening agar base for detection of methicillin-resistant Staphylococcus aureus. J. Clin. Microbiol. 2002, 40:4400-4401.
6. Berger-Bachi B. Factors affecting methicillin resistance in Staphylococcus aureus. Int. J. Antimicrob. Agents 1995, 6:13-21.
7. Berger-Bachi B., Tschierske M. Role of Fem factors in methicillin resistance. Drug Res. Updates 1998, 1:325-335.
8. Cefai C., Ashurst S., Owens C. Human carriage of methicillin-resistant Staphylococcus aureus linked with pet dog. Lancet 1994, 344:539-540.
9. Chung M., Dickinson G., de Lencastre H., Tomasz A. International Clones of Methicillin-Resistant Staphylococcus aureus in Two Hospitals in Miami, Florida. J. Clin. Microbiol. 2004, 42:542-547.
10. CLSI Performance Standards for Antimicrobial Disk Susceptibility Tests; Sixteenth International Supplement 2006, Clinical and Laboratory Standards Institute, Wayne, PA, USA, Document M100-S16.
11. Deshpande L.M., Fritsche T.R., Jones R.N. Molecular epidemiology of selected multidrug-resistant bacteria: a global report from the SENTRY Antimicrobial Surveillance Program. Diagn. Microbiol. Infect. Dis. 2004, 49:231-236.
12. Duquette R.A., Nuttall T.J. Methicillin-resistant Staphylococcus aureus in dogs and cats: an emerging problem?. J. Small Anim. Pract. 2004, 45:591-597.
13. Enright M.C., Day N.P., Davies C.E., Peacock S.J., Spratt B.G. Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus. J. Clin. Microbiol. 2000, 38:1008-1015.
14. Enright M.C., Robinson D.A., Randle G., Feil E.J., Grundmann H., Spratt B.G. The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA). Proc. Natl. Acad. Sci. U.S.A. 2002, 99:7687-7692.
15. Goering R.V., Tenover F.C. Epidemiological interpretation of chromosomal macrorestriction fragments analysed by pulsed-field gel electrophoresis. J. Clin. Microbiol. 1997, 35:2432-2433.
16. Hanselman B.A., Kruth S.A., Rousseau J., Low D.E., Willey B.M., McGeer A., Weese J.S. Methicillin-resistant Staphylococcus aureus colonization in veterinary personnel. Emerg. Infect. Dis. 2006, 12:1933-1938.
17. Harmsen D., Claus H., Witte W., Rothganger J., Turnwald D., Vogel U. Typing of methicillin-resistant Staphylococcus aureus in a university hospital setting by using novel software for spa repeat determination and database management. J. Clin. Microbiol. 2003, 41:5442-5448.
18. Hawkey P.M. Molecular epidemiology of clinically significant antibiotic resistance genes. Br. J. Pharmacol. 2008, 153:406-413.
19. Jain A., Agarwal A., Verma R.K. Cefoxitin disc diffusion test for detection of methicillin-resistant staphylococci. J. Med. Microbiol. 2008, 57:957-961.
20. Ko K.S., Lee J.Y., Suh J.Y., Oh W.S., Peck K.R., Lee N.Y., Song J.H. Distribution of major genotypes among methicillin-resistant Staphylococcus aureus clones in Asian countries. J. Clin. Microbiol. 2005, 43:421-426.
21. Koreen L., Ramaswamy S.V., Graviss E.A., Naidich S., Musser J.M., Kreiswirth B.N. spa typing method for discriminating among Staphylococcus aureus isolates: implications for use of a single marker to detect genetic micro- and macro-variation. J. Clin. Microbiol. 2004, 42:792-799.
22. Lim V.K. Staphylococcal infections in Malaysian hospitals. J. Hosp. Infect. 1988, 11:S103-S108.
23. Loeffler A., Boag A.K., Sung J., Lindsay J.A., Guardabassi L., Dalsgaard A., Smith H., Stevens K.B., Lloyd D.H. Prevalence of methicillin-resistant Staphylococcus aureus among staff and pets in a small animal referral hospital in the UK. J. Antimicrob. Chemother. 2005, 56:692-697.
24. Louie L., Goodfellow J., Mathieu P., Glatt A., Louie M., Simor A.E. Rapid detection of methicillin-resistant staphylococci from blood culture bottles by using a multiplex PCR assay. J. Clin. Microbiol. 2002, 40:2786-2790.
25. Maudsley J., Stone S.P., Kibbler C.C., Iliffe S.R., Conaty S.J., Cookson B.D., Duckworth G.J., Johnson A., Wallace P.G. The community prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in older people living in their own homes: implications for treatment, screening and surveillance in the UK. J. Hosp. Infect. 2004, 57:258-262.
26. Middleton J.R., Fales W.H., Luby C.D., Oask J.L., Sanchez S., Kinyon J.M., Wu C.C., Maddox C.W., Welsh R.D., Hartmann F. Surveillance of Staphylococcus aureus in veterinary teaching hospitals. J. Clin. Microbiol. 2005, 43:2916-2919.
27. Murchan S., Kaufmann M.E., Deplano A., de Ryck R., Struelens M., Zinn C.E., Fussing V., Salmenlinna S., Vuopio-Varkila J., El Solh N., Cuny C., Witte W., Tassios P.T., Legakis N., van Leeuwen W., van Belkum A., Vindel A., Laconcha I., Garaizar J., Haeggman S., Olsson-Liljequist B., Ransjo U., Coombes G., Cookson B. Harmonization of pulsed-field gel electrophoresis protocols for epidemiological typing of strains of methicillin-resistant Staphylococcus aureus: a single approach developed by consensus in 10 European laboratories and its application for tracing the spread of related strains. J. Clin. Microbiol. 2003, 41:1574-1585.
28. Neela V., Sasikumar M., Ghaznavi G.R., Zamberi S., Mariana S. In vitro Activities of 28 antimicrobial agents against methicillin-resistant Staphylococcus aureus (MRSA) from a clinical setting in Malaysia. South Asian J. Trop. Med. Public Health 2008, 39:885-892.
29. Norazah A., Izayu R., Kamel M.A.G., Azura H., Salbiah N., Nazri M.A., Nurahan M., Lim V.K.E. The characteristics of methicillin-resistant Staphylococcus aureus strains carrying SCCmec type IV isolated from community and hospital-acquired methicillin-resistant Staphylococcus aureus from Malaysia. J. Med. Microbiol. 2009, 58:1213-1218.
30. Nulens E., Stobberingh E.E., van Dessel H., Sebastian S., van Tiel F.H., Beisser P.S., Deurenberg R.H. Molecular characterization of Staphylococcus aureus bloodstream isolates collected in a Dutch University hospital between 1999 and 2006. J. Clin. Microbiol. 2008, 46:2438-2441.
31. Nuttall T., Williams N., Saunders R., Dawson S. Methicillin-resistant staphylococci in companion animals. Eur. J. Companion Anim. Pract. 2008, 18:280-287.
32. O'Mahony R., Abbott Y., Leonard F.C., Markey B.K., Quinn P.J., Pollock P.J., Fanning S., Rossney A.S. Methicillin-resistant Staphylococcus aureus (MRSA) isolated from animals and veterinary personnel in Ireland. Vet. Microbiol. 2005, 109:285-296.
33. Oliveira D.C., Tomasz A., de Lencastre H. Secrets of success of a human pathogen: molecular evolution of pandemic clones of methicillin-resistant Staphylococcus aureus. Lancet Infect. Dis. 2002, 2:180-189.
34. Otter J.A., French G.L. Molecular epidemiology of community-associated meticillin-resistant Staphylococcus aureus in Europe. Lancet Infect. Dis. 2010, 10:227-239.
35. Palavecino E. Clinical, epidemiological, and laboratory aspects of methicillin-resistant Staphylococcus aureus (MRSA) infections. Methods in molecular biology: methicillin-resistant Staphylococcus aureus (MRSA) protocols 2007, 1-19. Humana Press, Totawa, NJ. Y. Ji (Ed.).
36. Rohani M.Y., Raudzah A., Lau M.G., Zaidatul A.A.R., Salbiah M.N., Keah K.C., Noraini A., Zainuldin T. Susceptibility pattern of Staphylococcus aureus isolated in Malaysian hospitals. Int. J. Antimicrob. Agent 2000, 13:209-213.
37. Sanches I.S., Aires-de Sousa M.A., Cleto L., de Campos M.B., de Lencastre H. Tracing the origin of an outbreak of methicillin-resistant Staphylococcus aureus infections in a Portuguese hospital by molecular fingerprinting methods. Microb. Drug Resist. 1996, 2:319-329.
38. Seguin J.C., Walker R.D., Caron J.P., Kloos W.E., Geworge C.G., Hollis R.J., Jones R.N., Pfaller M.A. Methicillin-resistant Staphylococcus aureus. Outbreak in veterinary teaching hospital: potential human-to-animal transmission. J. Clin. Microbiol. 1999, 37:1459-1463.
39. Struelens M.J., Deplano A., Godard C., Maes N., Serruys E. Epidemiologic typing and delineation of genetic relatedness of methicillinresistant Staphylococcus aureus by macrorestriction analysis of genomic DNA by using pulsed-field gel electrophoresis. J. Clin. Microbiol. 1992, 30:2599-2605.
40. Tenover F.C., Arbeit R.D., Goering R.V., Mickelsen P.A., Murray B.E., Persing D.H., Swaminathan B. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J. Clin. Microbiol. 1995, 33:2233-2239.
41. Tong S.Y.C., McDonald M.I., Holt D.C., Currie B.J. Global implications of the emergence of community-associated methicillin-resistant Staphylococcus aureus in indigenous populations. Clin. Infect. Dis. 2008, 46:1871-1878.
42. van Duijkeren E., Wolfhagen M.J.H.M., Box A.T., Wannet W.J., Fluit A.C. Human-to-dog transmission of methicillin-resistant Staphylococcus aureus. Emerg. Infect. Dis. 2004, 10:2235-2237.
43. Weese J.S. Methicillin-resistant Staphylococcus aureus in horses and horse personnel. Vet. Clin. North Am. Equine Pract. 2004, 20:601-613.
44. Weese J.S., Dick H., Willey B.M., McGeer A., Kreiswirth B.N., Innis B., low D.E. Suspected transmission of methicillin-resistant Staphylococcus aureus between domestic pets and humans in veterinary clinics and in the household. Vet. Microbiol. 2006, 115:148-155.
45. Williams N.J., Deacon V., Pinchbeck G., Dawson S. A pilot survey of the prevalence of methicllin-resistant Staphylococcus aureus (MRSA) and other methicillin resistant staphylococci (MRS) nasal carriage in small animal veterinary personnel. British Small Animal Veterinary Association Congress 2007.
46. Wulf M., van Nes A., Eikelenboom-Boskamp A., de Vries J., Melchers W., Klaassen C., Voss A. Methicillin-resistant Staphylococcus aureus in veterinary doctors and students, the Netherlands. Emerg. Infect. Dis. 2006, 12:1939-1941.
47. Zaraket H., Otsuka T., Saito K., Dohmae S., Takano T., Higuchi W., TakeshiOhkubo T., Ozaki K., Takano M., Reva I., Baranovich T., Yamamoto T. Molecular characterization of methicillin-resistant Staphylococcus aureus in hospitals in Niigata, Japan: divergence and transmission. Microbiol. Immunol. 2007, 51:171-176.