Continuous stress promotes expression of VGF in melanotroph via suppression of dopamine

Molecular and Cellular Endocrinology

Volumn 372, Issue 1-2, 2013, Pages 49-56

  Tokizane, Kyohei ^a   Konishi, Hiroyuki ^a   Yasui, Masaya ^a   Ogawa, Tokiko ^c   Sasaki, Kazuki ^b   Minamino, Naoto ^b   Kiyama, Hiroshi ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^c OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Chronic fatigue syndrome; Chronic stress; Dopamine; Hypothalamus; Pituitary

Indexed keywords

BROMOCRIPTINE; CELL PROTEIN; DOPAMINE; MESSENGER RNA; PEPTIDE; PROTEIN ANTIBODY; PROTEIN VGF; SULPIRIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTONOMIC INNERVATION; CARBOXY TERMINAL SEQUENCE; CELL STRESS; CELL SUBPOPULATION; CHRONIC FATIGUE SYNDROME; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; HYPOPHYSIS; HYPOPHYSIS INTERMEDIATE LOBE; HYPOTHALAMUS; IN VITRO STUDY; MALE; MELANOTROPH; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; RAT; UPREGULATION;

ANIMALS; BROMOCRIPTINE; CELLS, CULTURED; DOPAMINE; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; DOPAMINERGIC NEURONS; GENE EXPRESSION; HYPOTHALAMUS; MALE; MELANOTROPHS; NEUROPEPTIDES; PITUITARY GLAND, INTERMEDIATE; PRIMARY CELL CULTURE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; SULPIRIDE; TRANSCRIPTIONAL ACTIVATION;

EID: 84877147911     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.03.012     Document Type: Article

References (33)

1. Alder J., Thakker-Varia S., Bangasser D.A., Kuroiwa M., Plummer M.R., Shors T.J., Black I.B. Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity. J. Neurosci. 2003, 23:10800-10808.
2. Bartolomucci A., Pasinetti G.M., Salton S.R. Granins as disease-biomarkers: translational potential for psychiatric and neurological disorders. Neuroscience 2010, 170:289-297.
3. Bartolomucci A., Possenti R., Mahata S.K., Fischer-Colbrie R., Loh Y.P., Salton S.R. The extended granin family: structure, function, and biomedical implications. Endocr. Rev. 2011, 32:755-797.
4. Cote T.E., Eskay R.L., Frey E.A., Grewe C.W., Munemura M., Stoof J.C., Tsuruta K., Kebabian J.W. Biochemical and physiological studies of the beta-adrenoceptor and the D-2 dopamine receptor in the intermediate lobe of the rat pituitary gland: a review. Neuroendocrinology 1982, 35:217-224.
5. D'Amato F., Noli B., Brancia C., Cocco C., Flore G., Collu M., Nicolussi P., Ferri G.L. Differential distribution of VGF-derived peptides in the adrenal medulla and evidence for their selective modulation. J. Endocrinol. 2008, 197:359-369.
6. D'Amato F., Cocco C., Noli B., Cabras T., Messana I., Ferri G.L. VGF peptides upon osmotic stimuli: changes in neuroendocrine regulatory peptides 1 and 2 in the hypothalamic-pituitary-axis and plasma. J. Chem. Neuroanat. 2012, 44:57-65.
7. Fujihara H., Sasaki K., Mishiro-Sato E., Ohbuchi T., Dayanithi G., Yamasaki M., Ueta Y., Minamino N. Molecular characterization and biological function of neuroendocrine regulatory peptide-3 in the rat. Endocrinology 2012, 153:1377-1386.
8. Hawley R.J., Scheibe R.J., Wagner J.A. NGF induces the expression of the VGF gene through a cAMP response element. J. Neurosci. 1992, 12:2573-2581.
9. Katafuchi T., Kikumoto K., Hamano K., Kangawa K., Matsuo H., Minamino N. Calcitonin receptor-stimulating peptide, a new member of the calcitonin gene-related peptide family. Its isolation from porcine brain, structure, tissue distribution, and biological activity. J. Biol. Chem. 2003, 278:12046-12054.
10. Kiryu-Seo S., Sasaki M., Yokohama H., Nakagomi S., Hirayama T., Aoki S., Wada K., Kiyama H. Damage-induced neuronal endopeptidase (DINE) is a unique metallopeptidase expressed in response to neuronal damage and activates superoxide scavengers. Proc. Natl. Acad. Sci. USA 2000, 97:4345-4350.
11. Konishi H., Namikawa K., Shikata K., Kobatake Y., Tachibana T., Kiyama H. Identification of peripherin as a Akt substrate in neurons. J. Biol. Chem. 2007, 282:23491-23499.
12. Konishi H., Ogawa T., Nakagomi S., Inoue K., Tohyama M., Kiyama H. Id1, Id2 and Id3 are induced in rat melanotrophs of the pituitary gland by dopamine suppression under continuous stress. Neuroscience 2010, 169:1527-1534.
13. Konishi H., Ogawa T., Kawahara S., Matsumoto S., Kiyama H. Continuous stress-induced dopamine dysregulation augments PAP-I and PAP-II expression in melanotrophs of the pituitary gland. Biochem. Biophys. Res. Commun. 2011, 407:7-12.
14. Levi A., Eldridge J.D., Paterson B.M. Molecular cloning of a gene sequence regulated by nerve growth factor. Science 1985, 229:393-395.
15. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
16. Mahata S.K., Mahata M., Hortnag H., Fischer-Colbrie R., Steiner H.J., Dietze O., Winkler H. Concomitant changes of messenger ribonucleic acid levels of secretogranin II, VGF, vasopressin and oxytocin in the paraventricular nucleus of rats after adrenalectomy and during lactation. J. Neuroendocrinol. 1993, 5:323-330.
17. Mishiro-Sato E., Sasaki K., Matsuo T., Kageyama H., Yamaguchi H., Date Y., Matsubara M., Ishizu T., Yoshizawa-Kumagaye K., Satomi Y., Takao T., Shioda S., Nakazato M., Minamino N. Distribution of neuroendocrine regulatory peptide-1 and -2, and proteolytic processing of their precursor VGF protein in the rat. J. Neurochem. 2010, 114:1097-1106.
18. Moss A., Ingram R., Koch S., Theodorou A., Low L., Baccei M., Hathway G.J., Costigan M., Salton S.R., Fitzgerald M. Origins, actions and dynamic expression patterns of the neuropeptide VGF in rat peripheral and central sensory neurones following peripheral nerve injury. Mol. Pain 2008, 4:62.
19. Nagata K., Kiryu-Seo S., Maeda M., Yoshida K., Morita T., Kiyama H. Damage-induced neuronal endopeptidase is critical for presynaptic formation of neuromuscular junctions. J. Neurosci. 2010, 30:6954-6962.
20. Ogawa T., Kiryu-Seo S., Tanaka M., Konishi H., Iwata N., Saido T., Watanabe Y., Kiyama H. Altered expression of neprilysin family members in the pituitary gland of sleep-disturbed rats, an animal model of severe fatigue. J. Neurochem. 2005, 95:1156-1166.
21. Ogawa T., Shishioh-Ikejima N., Konishi H., Makino T., Sei H., Kiryu-Seo S., Tanaka M., Watanabe Y., Kiyama H. Chronic stress elicits prolonged activation of alpha-MSH secretion and subsequent degeneration of melanotroph. J. Neurochem. 2009, 109:1389-1399.
22. Ogawa T., Sei H., Konishi H., Shishioh-Ikejima N., Kiyama H. The absence of somatotroph proliferation during continuous stress is a result of the lack of extracellular signal-regulated kinase 1/2 activation. J. Neuroendocrinol. 2012, 24:1335-1345.
23. Riedl M.S., Braun P.D., Kitto K.F., Roiko S.A., Anderson L.B., Honda C.N., Fairbanks C.A., Vulchanova L. Proteomic analysis uncovers novel actions of the neurosecretory protein VGF in nociceptive processing. J. Neurosci. 2009, 29:13377-13388.
24. Salton S.R., Fischberg D.J., Dong K.W. Structure of the gene encoding VGF, a nervous system-specific mRNA that is rapidly and selectively induced by nerve growth factor in PC12 cells. Mol. Cell. Biol. 1991, 11:2335-2349.
25. Salton S.R., Ferri G.L., Hahm S., Snyder S.E., Wilson A.J., Possenti R., Levi A. VGF: a novel role for this neuronal and neuroendocrine polypeptide in the regulation of energy balance. Front. Neuroendocrinol. 2000, 21:199-219.
26. Sasaki K., Takahashi N., Satoh M., Yamasaki M., Minamino N. A peptidomics strategy for discovering endogenous bioactive peptides. J. Proteome Res. 2010, 9:5047-5052.
27. Sasaki K., Osaki T., Minamino N. Large-scale identification of endogenous secretory peptides using electron transfer dissociation mass spectrometry. Mol. Cell. Proteomics 2012.
28. Sei C., Toneff T., Aaron W., Hook V.Y. Regulation of cellular alpha-MSH and beta-endorphin during stimulated secretion from intermediate pituitary cells: involvement of aspartyl and cysteine proteases in the control of cellular levels of alpha-MSH and beta-endorphin. Peptides 2002, 23:1409-1418.
29. Shishioh-Ikejima N., Ogawa T., Yamaguti K., Watanabe Y., Kuratsune H., Kiyama H. The increase of alpha-melanocyte-stimulating hormone in the plasma of chronic fatigue syndrome patients. BMC Neurol. 2010, 10:73.
30. Snyder S.E., Li J., Salton S.R. Comparison of VGF and trk mRNA distributions in the developing and adult rat nervous systems. Brain Res. Mol. Brain Res. 1997, 49:307-311.
31. Tanaka M., Nakamura F., Mizokawa S., Matsumura A., Nozaki S., Watanabe Y. Establishment and assessment of a rat model of fatigue. Neurosci. Lett. 2003, 352:159-162.
32. Taupenot L., Harper K.L., O'Connor D.T. The chromogranin-secretogranin family. N. Engl. J. Med. 2003, 348:1134-1149.
33. Yamaguchi H., Sasaki K., Satomi Y., Shimbara T., Kageyama H., Mondal M.S., Toshinai K., Date Y., Gonzalez L.J., Shioda S., Takao T., Nakazato M., Minamino N. Peptidomic identification and biological validation of neuroendocrine regulatory peptide-1 and -2. J. Biol. Chem. 2007, 282:26354-26360.