Epidemiology, clinical, immune, and molecular profiles of microsporidiosis and cryptosporidiosis among HIV/AIDS patients

International Journal of General Medicine

Volumn 5, Issue , 2012, Pages 603-611

  Wumba, Roger ^a   Longo Mbenza, Benjamin ^b   Menotti, Jean ^c,d   Mandina, Madone ^a   Kintoki, Fabien ^a   Situakibanza, Nani Hippolyte ^a   Kakicha, Marie Kapepela ^a   Zanga, Josue ^a   Mbanzulu Makola, Kennedy ^a   Nseka, Tommy ^a   Mukendi, Jean Pierre ^a   Kendjo, Eric ^e   Sala, Jean ^a   Thellier, Marc ^e  

^a UNIVERSITY OF KINSHASA   (Congo)

^b WALTER SISULU UNIVERSITY   (South Africa)

^c SAINT LOUIS HOSPITAL   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Africans; Cryptosporidium hominis; Cryptosporidium parvum; Diarrhea; Enterocytozoon bieneusi; Risk factors

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADOLESCENT; ADULT; AGED; ARTICLE; ASTHENIA; CD4 LYMPHOCYTE COUNT; CHRONIC DIARRHEA; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; CRYPTOSPORIDIOSIS; CRYPTOSPORIDIUM HOMINIS; CRYPTOSPORIDIUM PARVUM; DISEASE ASSOCIATION; DISEASE SURVEILLANCE; DNA SEQUENCE; ENCEPHALITOZOON INTESTINALIS; ENTAMOEBA COLI; ENTEROCYTOZOON; FECES ANALYSIS; FEMALE; GASTROINTESTINAL INFECTION; GENOTYPE; HERPES ZOSTER; HOST PARASITE INTERACTION; HUMAN; IMMUNOFLUORESCENCE TEST; INFECTION RISK; ISOSPORA BELLI; KAPOSI SARCOMA; MAJOR CLINICAL STUDY; MALE; MICROSPORIDIOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OPPORTUNISTIC INFECTION; PARASITE PREVALENCE; PARASITE TRANSMISSION; REAL TIME POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SENSITIVITY ANALYSIS; SEQUENCE ANALYSIS;

EID: 84877145541     PISSN: None     EISSN: 11787074     Source Type: Journal    
DOI: 10.2147/IJGM.S32344     Document Type: Article

References (57)

1. Dwivedi KK, Prasad G, Saini S, Mahajan S, Lal S, Baveja UK. Enteric opportunistic parasites among HIV infected individuals: associated risk factors and immune status. Jpn J Infect Dis. 2007;60(2-3):76-81.
2. Bern C, Kawai V, Vargas D, et al. The epidemiology of intestinal microsporidiosis in patients with HIV/AIDS in Lima, Peru. J Infect Dis. 2005;191(10):1658-1664.
3. Gumbo T, Sarbah S, Gangaidzo IT, et al. Intestinal parasites in patients with diarrhea and human immunodeficiency virus infection in Zimbabwe. AIDS. 1999;13(7):819-821.
4. Akinbo FO, Okaka CE, Omoregie R. Prevalence of intestinal parasitic infections among HIV patients in Benin City, Nigeria. Libyan J Med. 2010;5:doi:10.3402/ljm.v5i0.5506.
5. Rabeneck L, Gyorkey F, Genta RM, Gyorkey P, Foote LW, Risser JM. The role of microsporidia in the pathogenesis of HIV-related chronic diarrhea. Ann Intern Med. 1993;119(9):895-899.
6. Leelayoova S, Subrungruang I, Rangsin R, et al. Transmission of Enterocytozoon bieneusi genotype a in a Thai orphanage. Am J Trop Med Hyg. 2005;73(1):104-107.
7. Assefa S, Erko B, Medhin G, Assefa Z, Shimelis T. Intestinal parasitic infections in relation to HIV/AIDS status, diarrhea and CD4 T-cell count. BMC Infect Dis. 2009;9:155.
8. Anane S, Attouchi H. Microsporidiosis: epidemiology, clinical data and therapy. Gastroenterol Clin Biol. 2010;34(8-9):450-464.
9. Nel ED, Rabie H, Goodway J, Cotton MF. A retrospective study of cryptosporidial diarrhea in a region with high HIV prevalence. J Trop Pediatr. 2011;57(4):289-592.
10. Abarca VK, López Del PJ, Peña DA, López GJ. Pet ownership and health status of pets from immunocompromised children, with emphasis in zoonotic diseases. Rev Chilena Infectol. 2011;28(3):205-210. Spanish.
11. Erhabor O, Obunge O, Awah I. Cryptosporidiosis among HIV-infected persons in the Niger Delta of Nigeria. Niger J Med. 2011;20(3):372-375.
12. Barrett DM, Steel-Duncan J, Christie CD, Eldemire-Shearer D, Lindo JF. Absence of opportunistic parasitic infestations in children living with HIV/AIDS in children's homes in Jamaica: pilot investigations. West Indian Med J. 2008;57(3):253-256.
13. Asmuth DM, DeGirolami PC, Federman M, et al. Clinical features of microsporidiosis in patients with AIDS. Clin Infect Dis. 1994;18(5):819-825.
14. McOliver CC, Lemerman HB, Silbergeld EK, Moore RD, Graczyk TK. Risks of recreational exposure to waterborne pathogens among persons with HIV/AIDS in Baltimore, Maryland. Am J Public Health. 2009;99(6):1116-1122.
15. Omoruyi B, Matongo F, Nkwetshana NT, Green E, Clarke AM, Ndip RN. Environmental and demographic risk factors associated with the prevalence of cryptosporidium infection in the Alice rural settlements of the Eastern Cape Province of South Africa: a pilot study. Rev Environ Health. 2011;26(2):127-133.
16. Voglino MC, Donelli G, Rossi P, et al. Intestinal microsporidiosis in Italian individuals with AIDS. Ital J Gastroenterol. 1996;28(7):381-386.
17. Del Aguila C, Navajas R, Gurbindo D, et al. Microsporidiosis in HIV-positive children in Madrid (Spain). J Eukaryot Microbiol. 1997;44(6):84S-85S.
18. Chacín-Bornilla L. Microsporidiosis: an emerging and opportunistic infection. Invest Clin. 2006;47(2):105-107.
19. Lobo ML, Xiao L, Antunes F, Matos O. Microsporidia as emerging pathogens and the implication for public health: a 10-year study on HIV-positive and-negative patients. Int J Parasitol. 2012;42(2):197-205.
20. Fisseha B, Petros B, WoldeMichael T. Cryptosporidium and other parasites in Ethiopian AIDS patients with chronic diarrhea. East Afr Med J. 1998;75(2):100-101.
21. Wumba R, Enache-Angoulvant A, Develoux M, et al. Prevalence of opportunistic digestive parasitic infections in Kinshasa, Democratic Republic of Congo. Results of a preliminary study in 50AIDS patients. Med Trop (Mars). 2007;67(2):145-148.
22. Wumba R, Longo-Mbenza B, Mandina M, et al. Intestinal parasites infections in hospitalized AIDS patients in Kinshasa, Democratic Republic of Congo. Parasite. 2010;17(4):321-328.
23. World Health Organization. WHO case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV-related disease in adults aged 15 years or older. New Delhi, India: WHO SEARO Publication on HIV/AIDS; 2006.
24. Ritchie LS. An ether sedimentation technique for routine stool examinations. Bull U S Army Med Dep. 1948;8(4):326.
25. Henriksen SA, Pohlenz JF. Staining of cryptosporidia by a modified Ziehl-Neelsen technique. Acta Vet Scand. 1981;22(3-4):594-596.
26. Accoceberry I, Thellier M, Desportes-Livage I, et al. Production of monoclonal antibodies directed against the microsporidium. Enterocytozoon bieneusi. J Clin Microbiol. 1999;37(12):4107-4112.
27. Menotti J, Cassinat B, Porcher R, Sarfati C, Derouin F, Molina JM. Development of a real-time polymerase-chain-reaction assay for quantitative detection of Enterocytozoon bieneusi DNA in stool specimens from immunocompromised patients with intestinal microsporidiosis. J Infect Dis. 2003;187(9):1469-1474.
28. Fontaine M, Guillot E. Study of 18S rRNA and rDNA stability by real-time RT-PCR in heat-inactivated Cryptosporidium parvum oocysts. FEMS Microbiol Lett. 2003;226(2):237-243.
29. Guitard J, Menotti J, Desveaux A, et al. Experimental study of the effects of probiotics on Cryptosporidium parvum infection in neonatal rats. Parasitol Res. 2006;99(5):522-527.
30. Coupe S, Sarfati C, Hamane S, Derouin F. Detection of cryptosporidium and identification to the species level by nested PCR and restriction fragment length polymorphism. J Clin Microbiol. 2005;43(3):1017-1023.
31. Breton J, Bart-Delabesse E, Biligui S, et al. New highly divergent rRNA sequence among biodiverse genotypes of Enterocytozoon bieneusi strains isolated from humans in Gabon and Cameroon. J Clin Microbiol. 2007;45(8):2580-2589.
32. Katzwinkel-Wladarsch S, Lieb M, Helse W, Löscher T, Rinder H. Direct amplification and species determination of microsporidian DNA from stool specimens. Trop Med Int Health. 1996;1(3):373-378.
33. Genbank® [database on the Internet]. Bethesda, MD: National Center for Biotechnology Information, US Library of Medicine; nd [updated November 11, 2011]. Available from: http://www.ncbi.nlm.nih.gov/genbank/. Accessed May 29, 2012.
34. Ndao M. Diagnosis of parasitic diseases: old and new approaches. Interdiscip Perspect Infect Dis. 2009;2009:278246.
35. Kawashi FN, Longo-Mbenza B, Matanda NR, Nge-Okwe A, Fuele SM. Sociodemographic and semiological characteristics of ENT the sphere in patients with HIV/AIDS in Kinshasa, DR Congo. Pan Afr Med J. 2010;7:15.
36. Mash B, Fairall L, Adejayan O, et al. A morbidity survey of South African primary care. PLoS One. 2012;7(3):e32358.
37. Mucheto P, Chadambuka A, Shambira G, Tshimanga M, Gombe N, Nyamayaro W. Determinants of nondisclosure of HIV status among women attending the prevention of mother to child transmission programme, Makonde district, Zimbabwe, 2009. Pan Afr Med J. 2011;8:51.
38. Likatavicius G, Van de Laar MJ. HIV and AIDS in the European Union, 2009. Euro Surveill. 2010;15(48):19737.
39. Cotte L, Rabodonirina M, Chapuis F, et al. Waterborne outbreak of intestinal microsporidiosis in persons with and without human immunodeficiency virus infection. J Infect Dis. 1999;180(6):2003-2008.
40. Bergquist R, Morfeldt-Månsson L, Pehrson PO, Petrini B, Wasserman J. Antibody against Encephalitozoon cuniculi in Swedish homosexual men. Scand J Infect Dis. 1984;16(4):389-391.
41. Wittner M. Historic perspective on the microsporidia: expanding horizons. In: Wittner M, Weiss L, editors. Microsporidia and Microsporidiosis. Washington DC: American Society of Microbiology; 1999:24-31.
42. Didier ES, Stovall ME, Green LC, Brindley PJ, Sestak K, Didier PJ. Epidemiology of microsporidiosis: sources and modes of transmission. Vet Parasitol. 2004;126(1-2):145-166.
43. Espern A, Morio F, Miegeville M, et al. Molecular study of microsporidiosis due to Enterocytozoon bieneusi and Encephalitozoon intestinalis among human immunodeficiency virus-infected patients from two geographical areas: Niamey, Niger, and Hanoi, Vietnam. J Clin Microbiol. 2007;45(9):2999-3002.
44. Conteas CN, Berlin OG, Ash LR, Pruthi JS. Therapy for human gastrointestinal microsporidiosis. Am J Trop Med Hyg. 2000;63(3-4):121-127.
45. Weber R, Bryan RT, Schwartz DA, Owen RL. Human microsporidial infections. Clin Microbiol Rev. 1994;7(4):426-461.
46. Franzen C, Muller A. Molecular techniques for detection, species differentiation, and phylogenetic analysis of microsporidia. Clin Microbiol Rev. 1999;12(2):243-285.
47. Cheng HW, Lucy FE, Graczyk TK, Broaders MA, Mastitsky SE. Municipal wastewater treatment plants as removal systems and environment sources of human-virulent microsporidian spores. Parasitol Res. 2011;109(3):595-603.
48. Slodkowicz-Kowalska A, Graczyk TK, Tamang L, et al. Microsporidian species known to infect humans are present in aquatic birds: implications for transmission via water? Appl Environ Microbiol. 2006;72(7):4540-4544.
49. Lucy FE, Graczyk TK, Tamang L, Miraflor A, Minchin D. Biomonitoring of surface and coastal water for Cryptosporidium, Giardia and human-virulent microsporidia using molluscan shellfish. Parasitol Res. 2008;103(6):1369-1375.
50. Endeshaw T, Kebede A, Verweij JJ, et al. Intestinal microsporidiosis in diarrheal patients infected with human immunodeficiency virus-1 in Addis Ababa, Ethiopia. Jpn J Infect Dis. 2006;59(5):306-310.
51. Lebbad M, Norrgren H, Nauclér A, Dias F, Andersson S, Linder E. Intestinal parasites in HIV-2 associated AIDS cases with chronic diarrhea in Guinea-Bissau. Acta Trop. 2001;80(1):45-49.
52. Konate A, Minta D, Diarra M, et al. Intestinal parasitosis during AIDS diarrhoea. Bull Soc Pathol Exot. 2005;98(1):33-35.
53. Dworkin MS, Buskin SE, Davidson AJ, et al. Prevalence of intestinal microsporidiosis in human immunodeficiency virus-infected patients with diarrhea in major United States cities. Rev Inst Med Trop Sao Paulo. 2007;49(6):339-342.
54. Sarfati C, Bourgeois A, Menotti J, et al. Prevalence of intestinal parasites including microsporidia in human immunodeficiency virus-infected adults in Cameroon: a cross-sectional study. Am J Trop Med Hyg. 2006;74(1):162-164.
55. Hennequin C, Pialoux G, Bourre P, Dupont B. Microsporidiosis and acquired immunodeficiency syndrome (AIDS). Med Mal Infect. 1992;22(5):487-492.
56. Brady MT, Oleske JM, Williams PL, et al. Declines in mortality rates and changes in causes of death in HIV-1-infected children during the HAART era. J Acquir Immune Defic Syndr. 2010;53(1):86-94.
57. An W, Zhang D, Xiao S, Yu J, Yang M. Quantitative health risk assessment of Cryptosporidium in rivers of southern China based on continuous monitoring. Environ Sci Technol. 2011;45(11):4951-4958.