Schizophrenia susceptibility and age of diagnosis - A frailty approach

Schizophrenia Research

Volumn 147, Issue 1, 2013, Pages 140-146

  Svensson, Elisabeth ^a,b   Rogvin, Maria ^c   Hultman, Christina M ^d   Reichborn Kjennerud, Ted ^a,c   Sandin, Sven ^d   Moger, Tron A ^c  

^a NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^b AARHUS UNIVERSITY   (Denmark)

^c UNIVERSITY OF OSLO   (Norway)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Age factors; Genetic predisposition to disease epidemiology; Incidence; Risk factors; Schizophrenia; Susceptibility; Sweden

Indexed keywords

ADULT; AGE; ARTICLE; BIRTHPLACE; COHORT ANALYSIS; DISEASE REGISTRY; FAMILY HISTORY; FEMALE; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL MODEL; PATERNAL AGE; PRIORITY JOURNAL; PSYCHIATRIC DIAGNOSIS; PSYCHOLOGIC ASSESSMENT; REGRESSION ANALYSIS; RISK ASSESSMENT; RISK FACTOR; SCHIZOPHRENIA; SEASONAL VARIATION; SEX DIFFERENCE; URBAN RURAL DIFFERENCE;

ADOLESCENT; ADULT; AGE FACTORS; DISEASE SUSCEPTIBILITY; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MODELS, THEORETICAL; RISK FACTORS; SCHIZOPHRENIA; SWEDEN; YOUNG ADULT;

EID: 84877131523     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2013.03.004     Document Type: Article

References (30)

1. Aalen O.O., Tretli S. Analyzing incidence of testis cancer by means of a frailty model. Cancer Causes Control 1999, 10:285-292.
2. Aleman A., Kahn R.S., Selten J.P. Sex differences in the risk of schizophrenia: evidence from meta-analysis. Arch. Gen. Psychiatry 2003, 60:565-571.
3. Dalman C., Broms J., Cullberg J., Allebeck P. Young cases of schizophrenia identified in a national inpatient register - are the diagnoses valid?. Soc. Psychiatry Psychiatr. Epidemiol. 2002, 37:527-531.
4. Ekholm B., Ekholm A., Adolfsson R., Vares M., Osby U., Sedvall G.C., Jonsson E.G. Evaluation of diagnostic procedures in Swedish patients with schizophrenia and related psychoses. Nord. J. Psychiatry 2005, 59:457-464.
5. Gelman A., Hill J. Data Analysis Using Regression and Multilevel/Hierarchical Models 2006, Cambridge University Press, Cambridge.
6. Haugen M., Bray F., Grotmol T., Tretli S., Aalen O.O., Moger T.A. Frailty modeling of bimodal age-incidence curves of nasopharyngeal carcinoma in low-risk populations. Biostatistics 2009, 10:501-514.
7. Haukka J., Suvisaari J., Lonnqvist J. Increasing age does not decrease risk of schizophrenia up to age 40. Schizophr. Res. 2003, 61:105-110.
8. Hultman C.M., Sparen P., Takei N., Murray R.M., Cnattingius S. Prenatal and perinatal risk factors for schizophrenia, affective psychosis, and reactive psychosis of early onset: case-control study. BMJ 1999, 318:421-426.
9. Kong A., Frigge M.L., Masson G., Besenbacher S., Sulem P., Magnusson G., Gudjonsson S.A., Sigurdsson A., Jonasdottir A., Jonasdottir A., Wong W.S., Sigurdsson G., Walters G.B., Steinberg S., Helgason H., Thorleifsson G., Gudbjartsson D.F., Helgason A., Magnusson O.T., Thorsteinsdottir U., Stefansson K. Rate of de novo mutations and the importance of father's age to disease risk. Nature 2012, 488:471-475.
10. Laursen T.M., Munk-Olsen T., Nordentoft M., Bo M.P. A comparison of selected risk factors for unipolar depressive disorder, bipolar affective disorder, schizoaffective disorder, and schizophrenia from a Danish population-based cohort. J. Clin. Psychiatry 2007, 68:1673-1681.
11. Lee S.H., DeCandia T.R., Ripke S., Yang J., Sullivan P.F., Goddard M.E., Keller M.C., Visscher P.M., Wray N.R. Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs. Nat. Genet. 2012, 44:247-250.
12. Linscott R.J., van Os J. Systematic reviews of categorical versus continuum models in psychosis: evidence for discontinuous subpopulations underlying a psychometric continuum. Implications for DSM-V, DSM-VI, and DSM-VII. Annu. Rev. Clin. Psychol. 2010, 6:391-419.
13. Ludvigsson J.F., Andersson E., Ekbom A., Feychting M., Kim J.L., Reuterwall C., Heurgren M., Olausson P.O. External review and validation of the Swedish National Inpatient Register. BMC Publ. Health 2011, 11:450.
14. MacDonald A.W., Schulz S.C. What we know: findings that every theory of schizophrenia should explain. Schizophr. Bull. 2009, 35:493-508.
15. Malaspina D. Paternal factors and schizophrenia risk: de novo mutations and imprinting. Schizophr. Bull. 2001, 27:379-393.
16. Malaspina D., Harlap S., Fennig S., Heiman D., Nahon D., Feldman D., Susser E.S. Advancing paternal age and the risk of schizophrenia. Arch. Gen. Psychiatry 2001, 58:361-367.
17. Moger T.A., Aalen O.O., Halvorsen T.O., Storm H.H., Tretli S. Frailty modelling of testicular cancer incidence using Scandinavian data. Biostatistics 2004, 5:1-14.
18. Mortensen P.B., Pedersen C.B., Westergaard T., Wohlfahrt J., Ewald H., Mors O., Andersen P.K., Melbye M. Effects of family history and place and season of birth on the risk of schizophrenia. NEJM 1999, 340:603-608.
19. Murray R.M., Lewis S.W. Is schizophrenia a neurodevelopmental disorder?. Br. Med. J. (Clin. Res. Ed.) 1987, 295:681-682.
20. Osby U., Hammar N., Brandt L., Wicks S., Thinsz Z., Ekbom A., Sparen P. Time trends in first admissions for schizophrenia and paranoid psychosis in Stockholm County, Sweden. Schizophr. Res. 2001, 47:247-254.
21. Owen M.J. Implications of genetic findings for understanding schizophrenia. Schizophr. Bull. 2012, 38:904-907.
22. Petersen L., Mortensen P.B., Pedersen C.B. Paternal age at birth of first child and risk of schizophrenia. Am. J. Psychiatry 2011, 168:82-88.
23. Sullivan P.F., Kendler K.S., Neale M.C. Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch. Gen. Psychiatry 2003, 60:1187-1192.
24. Suvisaari J.M., Haukka J.K., Tanskanen A.J., Lonnqvist J.K. Decline in the incidence of schizophrenia in Finnish cohorts born from 1954 to 1965. Arch. Gen. Psychiatry 1999, 56:733-740.
25. Svensson E., Moger T.A., Tretli S., Aalen O.O., Grotmol T. Frailty modelling of colorectal cancer incidence in Norway: indications that individual heterogeneity in risk is related to birth cohort. Eur. J. Epidemiol. 2006, 21:587-593.
26. Svensson A.C., Lichtenstein P., Sandin S., Oberg S., Sullivan P.F., Hultman C.M. Familial aggregation of schizophrenia: the moderating effect of age at onset, parental immigration, paternal age and season of birth. Scand. J. Public Health 2012, 40:43-50.
27. Tandon R., Keshavan M.S., Nasrallah H.A. Schizophrenia, "just the facts" what we know in 2008. 2. Epidemiology and etiology. Schizophr. Res. 2008, 102:1-18.
28. The International Schizophrenia Consortium Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 2008, 455:237-241.
29. van Os J., Kenis G., Rutten B.P. The environment and schizophrenia. Nature 2010, 468:203-212.
30. Wohl M., Gorwood P. Paternal ages below or above 35years old are associated with a different risk of schizophrenia in the offspring. Eur. Psychiatry 2007, 22:22-26.