Crystal structure of L,D-transpeptidase Ldt Mt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis

Cell Research

Volumn 23, Issue 5, 2013, Pages 728-731

  Li, Wen Juan ^a,b   Li, De Feng ^a   Hu, Yong Lin ^a   Zhang, Xian En ^a   Bi, Li Jun ^a   Wang, Da Cheng ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CARBAPENEM DERIVATIVE; MEROPENEM; PEPTIDYLTRANSFERASE; THIENAMYCIN DERIVATIVE; TUBERCULOSTATIC AGENT;

AMINO ACID SUBSTITUTION; BINDING SITE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; LETTER; METABOLISM; MYCOBACTERIUM TUBERCULOSIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SUBSTITUTION; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; BINDING SITES; CARBAPENEMS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; MYCOBACTERIUM TUBERCULOSIS; PEPTIDYL TRANSFERASES; THIENAMYCINS;

MYCOBACTERIUM TUBERCULOSIS;

EID: 84877116129     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2013.53     Document Type: Letter

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