Genetic variants in sex hormone metabolic pathway genes and risk of esophageal squamous cell carcinoma

Carcinogenesis

Volumn 34, Issue 5, 2013, Pages 1062-1068

  Hyland, Paula L ^a,b   Freedman, Neal D ^c   Hu, Nan ^a   Tang, Ze Zhong ^d   Wang, Lemin ^a   Wang, Chaoyu ^a   Ding, Ti ^d   Fan, Jin Hu ^e   Qiao, You Lin ^e   Golozar, Asieh ^a   Wheeler, William ^f   Yu, Kai ^c   Yuenger, Jeff ^g   Burdett, Laurie ^g   Chanock, Stephen J ^g   Dawsey, Sanford M ^c   Tucker, Margaret A ^c   Goldstein, Alisa M ^a   Abnet, Christian C ^c   Taylor, Philip R ^a  

^a Division of Cancer Epidemiology and Genetics   (United States)

^b Division of Cancer Prevention   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d SHANXI CANCER HOSPITAL   (China)

^e PEKING UNION MEDICAL COLLEGE   (China)

^f INFORMATION MANAGEMENT SERVICES INC   (United States)

^g SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALCOHOL CONSUMPTION; ARTICLE; CANCER RISK; CHINA; CONTROLLED STUDY; CYP11A1 GENE; CYP1B1 GENE; CYP3A5 GENE; CYP3A7 GENE; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FEMALE; GENE; GENE INTERACTION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SEX HORMONE METABOLIC GENE; SHBG GENE; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; SULT2B1 GENE;

CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CHINA; ESOPHAGEAL NEOPLASMS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GONADAL STEROID HORMONES; HUMANS; INCIDENCE; MALE; METABOLIC NETWORKS AND PATHWAYS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; STOMACH NEOPLASMS;

EID: 84877101042     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgt030     Document Type: Article

References (50)

1. Parkin,D.M. et al. (2005) Global cancer statistics, 2002. CA. Cancer J. Clin., 55, 74-108.
2. Ferlay,J. et al. (2010) Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer, 127, 2893-2917.
3. Qiao,Y.L. et al. (2009) Total and cancer mortality after supplementation with vitamins and minerals: follow-up of the Linxian General Population Nutrition Intervention Trial. J. Natl. Cancer Inst., 101, 507-518.
4. WHO and I ARC World Cancer Report (2008). WHO. IARC, Lyon.
5. Lee,C.H. et al. (2007) Carcinogenetic impact of alcohol intake on squa-mous cell carcinoma risk of the oesophagus in relation to tobacco smoking. Eur. J. Cancer, 43, 1188-1199.
6. Pandeya,N. et al. (2009) Alcohol consumption and the risks of adenocar-cinoma and squamous cell carcinoma of the esophagus. Gastroenterology, 136, 1215-1224.
7. Tran,G.D. et al. (2005) Prospective study of risk factors for esophageal and gastric cancers in the Linxian general population trial cohort in China. Int. J. Cancer, 113, 456-463.
8. Wei,W.Q. et al. (2005) Risk factors for oesophageal squamous dysplasiain adult inhabitants of a high risk region of China. Gut, 54, 759-763.
9. Hu,N. et al. (1992) Familial aggregation of oesophageal cancer in Yangcheng County, Shanxi Province, China. Int. J. Epidemiol.,21, 877-882.
10. Gao,Y. et al. (2011) Risk factors for esophageal and gastric cancers in Shanxi Province, China: a case-control study. Cancer Epidemiol., 35
11. Yu,Y. et al. (1993) Retrospective cohort study of risk-factors for esophageal cancer in Linxian, People's Republic of China. Cancer Causes Control, 4, 195-202.
12. Carter,C.L. et al. (1992) Segregation analysis of esophageal cancer in 221 high-risk Chinese families. J. Natl. Cancer Inst., 84, 771-776.
13. Zhang,W. et al. (2000) Segregation analysis of esophageal cancer in a moderately high-incidence area of northern China. Am. J. Hum. Genet., 67,110-119.
14. Hiyama,T. et al. (2007) Genetic polymorphisms and esophageal cancer risk. Int. J. Cancer, 121, 1643-1658.
15. Yang,C.X. et al. (2005) Phase I/II enzyme gene polymorphisms and esophageal cancer risk: a meta-analysis of the literature. World J. Gastroenterol., 11, 2531-2538.
16. Zhang,H. et al. (2010) The high incidence of esophageal cancer in parts of China may result primarily from genetic rather than environmental factors. Dis. Esophagus, 23, 392-397.
17. Abnet,C.C. et al. (2010) A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. Nat. Genet., 42, 764-767.
18. Freedman,N.D. et al. (2010) The association of menstrual and reproductive factors with upper gastrointestinal tract cancers in the NIH-AARP cohort. Cancer, 116, 1572-1581.
19. Bodelon,C. et al. (2011) Hormonal factors and risks of esophageal squamous cell carcinoma and adenocarcinoma in postmenopausal women. Cancer Prev. Res. (Phila)., 4, 840-850.
20. Gallus,S. et al. (2001) Oesophageal cancer in women: tobacco, alcohol, nutritional and hormonal factors. Br. J. Cancer, 85, 341-345.
21. Wang,Q.M. et al. (2011) Relevance of serum estradiol and estrogen receptor beta expression from a high-incidence area for esophageal squamous cell carcinoma in China. Med. Oncol., 28, 188-193.
22. Nozoe,T. et al. (2007) Significance of immunohistochemical expression of estrogen receptors alpha and beta in squamous cell carcinoma of the esophagus. Clin. Cancer Res., 13, 4046-050.
23. Kalayarasan,R. et al. (2008) Estrogen and progesterone receptors in esophageal carcinoma. Dis. Esophagus, 21, 298-303.
24. Matsuoka,H. et al. (1990) Estradiol sensitivity test using contact-sensitive plates of confluent BALB/c 3T3 cell monolayers. Cancer Res., 50, 2113-2118.
25. Rashid,F. et al. (2010) Probing the link between oestrogen receptors and oesophageal cancer. World J. Surg. Oncol., 8, 9.
26. Ueo,H. et al. (1990) Inhibitory effects of estrogen on the growth of a human esophageal carcinoma cell line. Cancer Res., 50, 7212-7215.
27. Yamashita,Y. et al. (1989) Detection of androgen receptors in human esophageal cancer. Jpn. J. Surg., 19, 195-202.
28. Tihan,T. et al. (2001) Evidence of androgen receptor expression in squamous and adenocarcinoma of the esophagus. Anticancer Res., 21(4B), 3107-3114.
29. Taylor,P.R. et al. (1994) Prevention of esophageal cancer: the nutrition intervention trials in Linxian, China. Linxian Nutrition Intervention Trials Study Group. Cancer Res., 54(7 Suppl), 2029s-2031s.
30. Li,B. et al. (1993) Linxian nutrition intervention trials. Design, methods, participant characteristics, and compliance. Ann. Epidemiol., 3, 577-585.
31. Miller,W.L. (2008) Steroidogenic enzymes. Endocr. Dev., 13, 1-18.
32. Payne,A.H. et al. (2004) Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. Endocr. Rev., 25, 947-970.
33. Li,L. et al. (2010). Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer. Breast Canc. Res., 12, R19.
34. Yang,H.P. et al. (2010) Common genetic variation in the sex hormone metabolic pathway and endometrial cancer risk: pathway-based evaluation of candidate genes. Carcino gene sis, 31, 827-833.
35. Aoki,K.F. et al. (2005) Using the KEGG database resource. Curr. Protoc. Bioinformatics, Chapter 1.
36. Yu,K. et al. (2009) Pathway analysis by adaptive combination of P-values. Genet. Epidemiol., 33, 700-709.
37. Jiang,J. et al. (2010) Association of genetic variations in aromatase gene with serum estrogen and estrogen/testosterone ratio in Chinese elderly men. Clin. Chim. Acta, 411, 53-58.
38. Eriksson,A.L. et al. (2009) Genetic variations in sex steroid-related genes as predictors of serum estrogen levels in men. J. Clin. Endocrinol. Metab., 94, 1033-1041.
39. Vanbillemont,G. et al. (2009) Polymorphisms of the SHBG gene contribute to the interindividual variation of sex steroid hormone blood levels in young, middle-aged and elderly men. Clin. Endocrinol. (Oxf), 70, 303-310.
40. Rudolph,A. et al. (2011) Modification of menopausal hormone therapy-associated colorectal cancer risk by polymorphisms in sex steroid signaling, metabolism and transport related genes. Endocr. Relat. Cancer, 18, 371-384.
41. Ji,Y. et al. (2007) Human hydroxysteroid sulfotransferase SULT2B1 pharmacogenomics: gene sequence variation and functional genomics. J. Pharmacol. Exp. Ther., 322, 529-540.
42. Hanna,I.H. et al. (2000) Cytochrome P450 1B1 (CYP1B1) pharmacoge-netics: association of polymorphisms with functional differences in estrogen hydroxylation activity. Cancer Res., 60, 3440-3444.
43. Lee,S.J. et al. (2005) Functionally defective or altered CYP3A4 and CYP3A5 single nucleotide polymorphisms and their detection with geno-typing tests. Pharmacogenomics, 6, 357-371.
44. Lamba,J.K. et al. (2002) Genetic contribution to variable human CYP3A-mediated metabolism. Adv. Drug Deliv. Rev., 54, 1271-1294.
45. Kuehl,P. et al. (2001) Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat. Genet., 27, 383-391.
46. Dandara,C. et al. (2005) CYP3A5 genotypes and risk of oesophageal cancer in two South African populations. Cancer Lett., 225, 275-282.
47. Thompson,D.J. et al. (2008) Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women. Cancer Epidemiol. Biomarkers Prev., 17, 3490-3498.
48. Freedman,N.D. et al. (2009) Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer. Carcinogenesis, 30, 71-77.
49. Kaczmarek,K. et al. (2009) Ccdc33, a predominantly testis-expressed gene, encodes a putative peroxisomal protein. Cytogenet. Genome Res., 126, 243-252.
50. Kobayashi,S. et al. (2010) Identification of a new secretory factor, CCDC3/ Favine, in adipocytes and endothelial cells. Biochem. Biophys. Res. Commun., 392, 29-35