The protective effect of modified intravenous immunoglobulin in LPS sepsis model is associated with an increased IRA B cells response

Autoimmunity Reviews

Volumn 12, Issue 6, 2013, Pages 653-656

  Djoumerska Alexieva, Iglika ^a   Pashova, Shina ^a   Vassilev, Tchavdar ^a   Pashov, Anastas ^a  

^a INSTITUTE OF MICROBIOLOGY   (Bulgaria)

Author keywords

B1 lymphocytes; CD93; Ferrous ions; Innate response activator B1 cells; Intravenous immunoglobulins; Sepsis

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN;

B LYMPHOCYTE; CELL MIGRATION; CELL SURVIVAL; CELLULAR IMMUNITY; IN VITRO STUDY; INNATE IMMUNITY; INNATE RESPONSE ACTIVATOR B CELL; LYMPHOCYTE; LYMPHOCYTE PROLIFERATION; NONHUMAN; PERITONEAL CAVITY; PERITONEUM CELL; REVIEW; SEPSIS;

ANIMALS; B-LYMPHOCYTES; CELLS, CULTURED; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC FACTORS; IRON; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED ICR; PERITONEAL CAVITY; SEPSIS;

EID: 84877084936     PISSN: 15689972     EISSN: 18730183     Source Type: Journal    
DOI: 10.1016/j.autrev.2012.10.010     Document Type: Review

References (21)

1. Saenko V.A., Rott G.M., Poverennyi A.M. Latent autoantibodies to cardiolipin in the blood serum of healthy subjects. Biull Eksp Biol Med 1989, 107:217-219.
2. Bobrovnik S.A. Transformation of serum immunoglobulins and monoclonal antibodies into polyreactive immunoglobulins. Ukr Biokhim Zh 1997, 69:97-109.
3. McMahon M.J., O'Kennedy R. Polyreactivity as an acquired artefact, rather than a physiologic property, of antibodies: evidence that monoreactive antibodies may gain the ability to bind to multiple antigens after exposure to low pH. J Immunol Methods 2000, 241:1-10.
4. Bouvet J.P., Stahl D., Rose S., Quan C.P., Kazatchkine M.D., Kaveri S.V. Induction of natural autoantibody activity following treatment of human immunoglobulin with dissociating agents. J Autoimmun 2001, 16:163-172.
5. Dimitrov J.D., Roumenina L.T., Doltchinkova V.R., Mihaylova N.M., Lacroix-Desmazes S., Kaveri S.V., et al. Antibodies use heme as a cofactor to extend their pathogen elimination activity and to acquire new effector functions. J Biol Chem 2007, 282:26696-26706.
6. Djoumerska-Alexieva I.K., Dimitrov J.D., Voynova E.N., Lacroix-Desmazes S., Kaveri S.V., Vassilev T.L. Exposure of IgG to an acidic environment results in molecular modifications and in enhanced protective activity in sepsis. FEBS J 2010, 277:3039-3050.
7. Fish F., Ziff M. Hidden anti-double stranded DNA antibodies in autoimmune mice. Clin Exp Immunol 1982, 49:587-597.
8. Saenko V.A., Kabakov A.E., Poverenny A.M. Hidden high-avidity anti-DNA antibodies occur in normal human gammaglobulin preparations. Immunol Lett 1992, 34:1-5.
9. Cabiedes J., Cabral A.R., Alarcon-Segovia D. Hidden anti-phospholipid antibodies in normal human sera circulate as immune complexes whose antigen can be removed by heat, acid, hypermolar buffers or phospholipase treatments. Eur J Immunol 1998, 28:2108-2114.
10. St-Amour I., Laroche A., Bazin R., Lemieux R. Activation of cryptic IgG reactive with BAFF, amyloid beta peptide and GM-CSF during the industrial fractionation of human plasma into therapeutic intravenous immunoglobulins. Clin Immunol 2009, 133:52-60.
11. Zoller-Utz I.M., Esslinger B., Schulze-Krebs A., Dieterich W. Natural hidden autoantibodies to tissue transglutaminase cross-react with fibrinogen. J Clin Immunol 2010, 30:204-212.
12. Dimitrov J.D., Ivanovska N.D., Lacroix-Desmazes S., Doltchinkova V.R., Kaveri S.V., Vassilev T.L. Ferrous ions and reactive oxygen species increase antigen-binding and anti-inflammatory activities of immunoglobulin G. J Biol Chem 2006, 281:439-446.
13. Dimitrov J.D., Lacroix-Desmazes S., Kaveri S.V., Vassilev T.L. Transition towards antigen-binding promiscuity of a monospecific antibody. Mol Immunol 2007, 44:1854-1863.
14. Djoumerska-Alexieva I.K., Dimitrov J.D., Nacheva J., Kaveri S.V., Vassilev T.L. Protein destabilizing agents induce polyreactivity and enhanced immunomodulatory activity in IVIg preparations. Autoimmunity 2009, 42:365-367.
15. Rauch P.J., Chudnovskiy A., Robbins C.S., Weber G.F., Etzrodt M., Hilgendorf I., et al. Innate response activator B cells protect against microbial sepsis. Science 2012, 335:597-601.
16. Djoumerska I.K., Tchorbanov A.I., Donkova-Petrini V.D., Pashov A.D., Vassilev T.L. Serum IgM, IgG and IgA block by F(ab')-dependent mechanism the binding of natural IgG autoantibodies from therapeutic immunoglobulin preparations to self-antigens. Eur J Haematol 2005, 74:101-110.
17. Labadi A., Balogh P. Differential preferences in serosal homing and distribution of peritoneal B-cell subsets revealed by in situ CFSE labeling. Int Immunol 2009, 21:1047-1056.
18. Sen G., Bikah G., Venkataraman C., Bondada S. Negative regulation of antigen receptor-mediated signaling by constitutive association of CD5 with the SHP-1 protein tyrosine phosphatase in B-1 B cells. Eur J Immunol 1999, 29:3319-3328.
19. Minguet S., Dopfer E.P., Pollmer C., Freudenberg M.A., Galanos C., Reth M., et al. Enhanced B-cell activation mediated by TLR4 and BCR crosstalk. Eur J Immunol 2008, 38:2475-2487.
20. Hayashi E.A., Granato A., Paiva L.S., Bertho A.L., Bellio M., Nobrega A. TLR4 promotes B cell maturation: independence and cooperation with B lymphocyte-activating factor. J Immunol 2010, 184:4662-4672.
21. Fillatreau S., Sweenie C.H., McGeachy M.J., Gray D., Anderton S.M. B cells regulate autoimmunity by provision of IL-10. Nat Immunol 2002, 3:944-950.