Losing Mom's message: Requirement for DCP1A and DCP2 in the degradation of maternal transcripts during oocyte maturation

Biology of Reproduction

Volumn 88, Issue 1, 2013, Pages

  Mehlmann, Lisa M ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DCP1A PROTEIN; DCP2 PROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; FERTILIZATION; GROWTH RATE; IN VITRO STUDY; METAPHASE; NONHUMAN; NOTE; OOCYTE DEVELOPMENT; OOCYTE MATURATION; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; RNA STABILITY;

ANIMALS; ENDORIBONUCLEASES; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; OOCYTES; PHOSPHORYLATION; PREGNANCY; RNA STABILITY; RNA, MESSENGER; TRANS-ACTIVATORS;

EID: 84877069906     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.112.106591     Document Type: Note

References (20)

1. Bachvarova R, DeLeon V. Polyadenylated RNA of mouse ova and loss of maternal RNA in early development. Dev Biol 1980; 74:1-8.
2. Brower PB, Gizang E, Boreen S, Schultz RM. Biochemical studies of mammalian oogenesis: synthesis and stability of various classes of RNA during growth of the oocyte in vitro. Dev Biol 1981; 86:373-383.
3. Schultz RM. Regulation of zygotic gene activation in the mouse. Bioessays 1993; 15:531-538.
4. Bachvarova R, De Leon V, Johnson A, Kaplan G, Paynton BV. Changes in total RNA, polyadenylated RNA, and actin mRNA during meiotic maturation of mouse oocytes. Dev Biol 1985; 108:325-331.
5. Su YQ, Sugiura K, Woo Y, Wigglesworth K, Kamdar S, Affourtit J, Eppig JJ. Selective degradation of transcripts during meiotic maturation of mouse oocytes. Dev Biol 2007; 302:104-117.
6. Stitzel ML, Seydoux G. Regulation of the oocyte-to-zygote transition. Science 2007; 316:407-408.
7. Ma J, Flemr M, Strnad H, Svoboda P, Schultz RM. Maternally-recruited DCP1A and DCP2 contribute to messenger RNA degradation during oocyte maturation and genome activation in mouse. Biol Reprod 2013; 88:11, 1-12.
8. Coller J, Parker R. Eukaryotic mRNA decapping. Annu Rev Biochem 2004; 73:861-890.
9. Paynton BV, Rempel R, Bachvarova R. Changes in state of adenylation and time course of degradation of maternal mRNAs during oocyte maturation and early embryonic development in the mouse. Dev Biol 1988; 129:304-314.
10. Yu J, Hecht NB, Schultz RM. Expression of MSY2 in mouse oocytes and preimplantation embryos. Biol Reprod 2001; 65:1260-1270.
11. Yu J, Hecht NB, Schultz, RM. RNA-binding properties and translation repression in vitro by germ cell-specific MSY2 protein. Biol Reprod 2002; 67:1093-1098.
12. Yu J, Deng M, Medvedev S, Yang J, Hecht NB, Schultz RM. Transgenic RNAi-mediated reduction of MSY2 in mouse oocytes results in reduced fertility. Dev Biol 2004; 268:195-206.
13. Medvedev S, Pan H, Schultz RM. Absence of MSY2 in mouse oocyte perturbs oocyte growth and maturation, RNA stability, and the transcriptome. Biol Reprod 2011; 85:575-583.
14. Yang J, Medvedev S, Yu J, Tang LC, Agno JE, Matzuk MM, Schultz RM, Hecht NB. Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility. Proc Natl Acad Sci U S A 2005; 102:5755-5760.
15. Medvedev S, Yang J, Hecht NB, Schultz RM. CDC2A (CDK1)-mediated phosphorylation of MSY2 triggers maternal mRNA degradation during mouse oocyte maturation. Dev Biol 2008; 321:205-215.
16. Beelman CA, Stevens A, Caponigro G, LaGrandeur TE, Hatfield L, Fortner DM, Parker R. An essential component of the decapping enzyme required for normal rates of mRNA turnover. Nature 1996; 382:642-646.
17. Dunckley T, Parker R. The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif. EMBO J 1999; 18:5411-5422.
18. Lykke-Andersen J. Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay. Mol Cell Biol 2002; 22:8114-8121.
19. van Dijk E, Cougot N, Meyer S, Babajko S, Wahle E, Seraphin B. Human Cdp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures. EMBO J 2002; 21:6915-6924.
20. Wang Z, Jiao X, Carr-Schmid A, Kiledjian M. The hDcp2 protein is a mammalian mRNA decapping enzyme. Proc Natl Acad Sci U S A 2002; 99:12663-12668.