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Volumn 14, Issue 4, 2013, Pages 8271-8290

Ovarian cancer: Can proteomics give new insights for therapy and diagnosis?

Author keywords

Biomarker; OVA1; Ovarian cancer; Proteomic; Therapy

Indexed keywords

GEFITINIB; HISTONE DEACETYLASE INHIBITOR; OLAPARIB; RETASPIMYCIN; THIOL SPECIFIC ANTIOXIDANT; TUMOR MARKER; UNCLASSIFIED DRUG; PROTEOME; TUMOR PROTEIN;

EID: 84877069374     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms14048271     Document Type: Review
Times cited : (33)

References (72)
  • 3
    • 78649427770 scopus 로고    scopus 로고
    • Proteomics as a guiding tool for more effective personalized therapy
    • Lee, J.M.; Kohn, E.C. Proteomics as a guiding tool for more effective personalized therapy. Ann. Oncol. 2010, 21, vii205-vii210.
    • (2010) Ann. Oncol , vol.21
    • Lee, J.M.1    Kohn, E.C.2
  • 4
    • 77956426658 scopus 로고    scopus 로고
    • Proteomics and ovarian cancer: Integrating proteomics information into clinical care
    • Hays, J.L.; Kim, G.; Giuroiu, I.; Kohn, E.C. Proteomics and ovarian cancer: Integrating proteomics information into clinical care. J. Proteomics 2010, 73, 1864-1872.
    • (2010) J. Proteomics , vol.73 , pp. 1864-1872
    • Hays, J.L.1    Kim, G.2    Giuroiu, I.3    Kohn, E.C.4
  • 5
    • 67649440886 scopus 로고    scopus 로고
    • The biology of ovarian cancer: New opportunities for translation
    • Bast, R.C., Jr.; Hennessy, B.; Mills, G.B. The biology of ovarian cancer: New opportunities for translation. Nat. Rev. Cancer 2009, 9, 415-428.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 415-428
    • Bast Jr., R.C.1    Hennessy, B.2    Mills, G.B.3
  • 7
    • 18344373769 scopus 로고    scopus 로고
    • Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract
    • Cheng, W.; Liu, J.; Yoshida, H.; Rosen, D.; Naora, H. Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract. Nat. Med. 2005, 11, 531-537.
    • (2005) Nat. Med , vol.11 , pp. 531-537
    • Cheng, W.1    Liu, J.2    Yoshida, H.3    Rosen, D.4    Naora, H.5
  • 8
    • 79959328816 scopus 로고    scopus 로고
    • Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer-shifting the paradigm
    • Kurman, R.J.; Shih, I.M. Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer-shifting the paradigm. Hum. Pathol. 2011, 42, 918-931.
    • (2011) Hum. Pathol , vol.42 , pp. 918-931
    • Kurman, R.J.1    Shih, I.M.2
  • 10
    • 41349100528 scopus 로고    scopus 로고
    • Pathogenesis of ovarian cancer: Lessons from morphology and molecular biology and their clinical implications
    • Kurman, R.J.; Shih, I.M. Pathogenesis of ovarian cancer: Lessons from morphology and molecular biology and their clinical implications. Int. J. Gynecol. Pathol. 2008, 27, 151-160.
    • (2008) Int. J. Gynecol. Pathol , vol.27 , pp. 151-160
    • Kurman, R.J.1    Shih, I.M.2
  • 11
    • 0142087616 scopus 로고    scopus 로고
    • Gynecologic Oncology Group Study. Prognostic significance of p53 mutation and p53 overexpression in advanced epithelial ovarian cancer: A Gynecologic Oncology Group Study
    • Havrilesky, L.; Darcy, K.M.; Hamdan, H.; Priore, R.L.; Leon, J.; Bell, J.; Berchuck, A. Gynecologic Oncology Group Study. Prognostic significance of p53 mutation and p53 overexpression in advanced epithelial ovarian cancer: A Gynecologic Oncology Group Study. J. Clin. Oncol. 2003, 21, 3814-3825.
    • (2003) J. Clin. Oncol , vol.21 , pp. 3814-3825
    • Havrilesky, L.1    Darcy, K.M.2    Hamdan, H.3    Priore, R.L.4    Leon, J.5    Bell, J.6    Berchuck, A.7
  • 16
    • 84870453484 scopus 로고    scopus 로고
    • A multidisciplinary clinic for individualizing management of patients at increased risk for breast and gynecologic cancer
    • Engel, N.J.; Gordon, P.; Thull, D.L.; Dudley, B.; Herstine, J.; Jankowitz, R.C.; Zorn, K.K. A multidisciplinary clinic for individualizing management of patients at increased risk for breast and gynecologic cancer. Fam. Cancer 2012, 11, 419-427.
    • (2012) Fam. Cancer , vol.11 , pp. 419-427
    • Engel, N.J.1    Gordon, P.2    Thull, D.L.3    Dudley, B.4    Herstine, J.5    Jankowitz, R.C.6    Zorn, K.K.7
  • 17
    • 0031958466 scopus 로고    scopus 로고
    • BRCA1, BRCA2, and hereditary nonpolyposis colorectal cancer gene mutations in an unselected ovarian cancer population: Relationship to family history and implications for genetic testing
    • Rubin, S.C.; Blackwood, M.A.; Bandera, C.; Behbakht, K.; Benjamin, I.; Rebbeck, T.R.; Boyd, J. BRCA1, BRCA2, and hereditary nonpolyposis colorectal cancer gene mutations in an unselected ovarian cancer population: Relationship to family history and implications for genetic testing. Am. J. Obstet. Gynecol. 1998, 178, 670-677.
    • (1998) Am. J. Obstet. Gynecol , vol.178 , pp. 670-677
    • Rubin, S.C.1    Blackwood, M.A.2    Bandera, C.3    Behbakht, K.4    Benjamin, I.5    Rebbeck, T.R.6    Boyd, J.7
  • 18
    • 18844445319 scopus 로고    scopus 로고
    • The molecular make-up of a tumour: Proteomics in cancer research
    • Kolch, W.; Mischak, H.; Pitt, A.R. The molecular make-up of a tumour: Proteomics in cancer research. Clin. Sci. (Lond.) 2005, 108, 369-383.
    • (2005) Clin. Sci. (Lond.) , vol.108 , pp. 369-383
    • Kolch, W.1    Mischak, H.2    Pitt, A.R.3
  • 22
    • 84871297843 scopus 로고    scopus 로고
    • Next-generation proteomics: Towards an integrative view of proteome dynamics
    • Altelaar, A.F.; Munoz, J.; Heck, A.J. Next-generation proteomics: towards an integrative view of proteome dynamics. Nat. Rev. Genet. 2013, 14, 35-48.
    • (2013) Nat. Rev. Genet , vol.14 , pp. 35-48
    • Altelaar, A.F.1    Munoz, J.2    Heck, A.J.3
  • 23
    • 77954464041 scopus 로고    scopus 로고
    • Proteomics: A pragmatic perspective
    • Mallick, P.; Kuster, B. Proteomics: A pragmatic perspective. Nat. Biotechnol. 2010, 28, 695-709.
    • (2010) Nat. Biotechnol , vol.28 , pp. 695-709
    • Mallick, P.1    Kuster, B.2
  • 26
    • 84866915917 scopus 로고    scopus 로고
    • Targeted mass spectrometry imaging: Specific targeting mass spectrometry imaging technologies from history to perspective
    • Gagnon, H.; Franck, J.; Wisztorski, M.; Day, R.; Fournier, I.; Salzet, M. Targeted mass spectrometry imaging: Specific targeting mass spectrometry imaging technologies from history to perspective. Prog. Histochem. Cytochem. 2012, 47, 133-174.
    • (2012) Prog. Histochem. Cytochem , vol.47 , pp. 133-174
    • Gagnon, H.1    Franck, J.2    Wisztorski, M.3    Day, R.4    Fournier, I.5    Salzet, M.6
  • 27
    • 84860848068 scopus 로고    scopus 로고
    • Mass spectrometry-based targeted quantitative proteomics: Achieving Sensitive and Reproducible Detection of Proteins
    • Boja, E.S.; Rodriguez, H. Mass spectrometry-based targeted quantitative proteomics: Achieving sensitive and reproducible detection of proteins. Proteomics 2012, 12, 1093-1110.
    • (2012) Proteomics , vol.12 , pp. 1093-1110
    • Boja, E.S.1    Rodriguez, H.2
  • 29
    • 48449084487 scopus 로고    scopus 로고
    • Application of genomic and proteomic technologies to early detection of cancer
    • Ardekani, A.M.; Akhondi, M.M.; Sadeghi, M.R. Application of genomic and proteomic technologies to early detection of cancer. Arch. Iran. Med. 2008, 11, 427-434.
    • (2008) Arch. Iran. Med , vol.11 , pp. 427-434
    • Ardekani, A.M.1    Akhondi, M.M.2    Sadeghi, M.R.3
  • 30
    • 17844377553 scopus 로고    scopus 로고
    • Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma
    • Sheehan, K.M.; Calvert, V.S.; Kay, E.W.; Lu, Y.; Fishman, D.; Espina, V.; Aquino, J.; Speer, R.; Araujo, R.MillsG.B.et al; Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma. Mol. Cell Proteomics 2005, 4, 346-355.
    • (2005) Mol. Cell Proteomics , vol.4 , pp. 346-355
    • Sheehan, K.M.1    Calvert, V.S.2    Kay, E.W.3    Lu, Y.4    Fishman, D.5    Espina, V.6    Aquino, J.7    Speer, R.8    Araujo, R.9    Mills, G.B.10
  • 31
    • 84863006290 scopus 로고    scopus 로고
    • Identifying cancer biomarkers by mass spectrometry-based glycomics
    • Mechref, Y.; Hu, Y.; Garcia, A.; Hussein, A. Identifying cancer biomarkers by mass spectrometry-based glycomics. Electrophoresis 2012, 33, 1755-1767.
    • (2012) Electrophoresis , vol.33 , pp. 1755-1767
    • Mechref, Y.1    Hu, Y.2    Garcia, A.3    Hussein, A.4
  • 33
    • 76649133774 scopus 로고    scopus 로고
    • Identification of candidate biomarkers with cancer-specific glycosylation in the tissue and serum of endometrioid ovarian cancer patients by glycoproteomic analysis
    • Abbott, K.L.; Lim, J.M.; Wells, L.; Benigno, B.B.; McDonald, J.F.; Pierce, M. Identification of candidate biomarkers with cancer-specific glycosylation in the tissue and serum of endometrioid ovarian cancer patients by glycoproteomic analysis. Proteomics 2010, 10, 470-481.
    • (2010) Proteomics , vol.10 , pp. 470-481
    • Abbott, K.L.1    Lim, J.M.2    Wells, L.3    Benigno, B.B.4    McDonald, J.F.5    Pierce, M.6
  • 34
    • 84877023639 scopus 로고    scopus 로고
    • Investigation of ovarian cancer associated sialylation changes in N-linked glycopeptides by quantitative proteomics
    • Shetty, V.; Hafner, J.; Shah, P.; Nickens, Z.; Philip, R. Investigation of ovarian cancer associated sialylation changes in N-linked glycopeptides by quantitative proteomics. Clin. Proteomics 2012, 9, 10.
    • (2012) Clin. Proteomics , vol.9 , pp. 10
    • Shetty, V.1    Hafner, J.2    Shah, P.3    Nickens, Z.4    Philip, R.5
  • 36
    • 84878109455 scopus 로고    scopus 로고
    • Cell signalling analyses in the functional genomics era
    • in press
    • Rogne, M.; TaskénK. Cell signalling analyses in the functional genomics era. New Biotechnol. 2013, in press.
    • (2013) New Biotechnol
    • Rogne, M.1    Taskén, K.2
  • 37
    • 84867036962 scopus 로고    scopus 로고
    • Enrichment techniques employed in phosphoproteomics
    • Fíla, J.; Honys, D. Enrichment techniques employed in phosphoproteomics. Amino Acids 2012, 43, 1025-1047.
    • (2012) Amino Acids , vol.43 , pp. 1025-1047
    • Fíla, J.1    Honys, D.2
  • 38
    • 78349310118 scopus 로고    scopus 로고
    • Phosphoproteomics in cancer
    • Harsha, H.C.; Pandey, A. Phosphoproteomics in cancer. Mol. Oncol. 2010, 4, 482-495.
    • (2010) Mol. Oncol , vol.4 , pp. 482-495
    • Harsha, H.C.1    Pandey, A.2
  • 41
    • 50349091687 scopus 로고    scopus 로고
    • The early detection of ovarian cancer: From traditional methods to proteomics. Can we really do better than serum CA-125
    • Nossov, V.; Amneus, M.; Su, F.; Lang, J.; Janco, J.M.; Reddy, S.T.; Farias-Eisner, R. The early detection of ovarian cancer: from traditional methods to proteomics. Can we really do better than serum CA-125? Am. J. Obstet. Gynecol. 2008, 199, 215-223.
    • (2008) Am. J. Obstet. Gynecol , vol.199 , pp. 215-223
    • Nossov, V.1    Amneus, M.2    Su, F.3    Lang, J.4    Janco, J.M.5    Reddy, S.T.6    Farias-Eisner, R.7
  • 44
    • 58549090494 scopus 로고    scopus 로고
    • Proteomic identification of tumor-associated protein in ovarian serous cystadenocarinoma
    • Li, X.Q.; Zhang, S.L.; Cai, Z.; Zhou, Y.; Ye, T.M.; Chiu, J.F. Proteomic identification of tumor-associated protein in ovarian serous cystadenocarinoma. Cancer Lett. 2009, 275, 109-116.
    • (2009) Cancer Lett , vol.275 , pp. 109-116
    • Li, X.Q.1    Zhang, S.L.2    Cai, Z.3    Zhou, Y.4    Ye, T.M.5    Chiu, J.F.6
  • 48
    • 84873027532 scopus 로고    scopus 로고
    • Utility of mesothelin, L1CAM and Afamin as biomarkers in primary ovarian cancer
    • Aktas, B.; Kasimir-Bauer, S.; Wimberger, P.; Kimmig, R.; Heubner, M. Utility of mesothelin, L1CAM and Afamin as biomarkers in primary ovarian cancer. Anticancer Res. 2013, 33, 329-336.
    • (2013) Anticancer Res , vol.33 , pp. 329-336
    • Aktas, B.1    Kasimir-Bauer, S.2    Wimberger, P.3    Kimmig, R.4    Heubner, M.5
  • 50
    • 16844374909 scopus 로고    scopus 로고
    • Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas
    • Drapkin, R.; von Horsten, H.H.; Lin, Y.; Mok, S.C.; Crum, C.P.; Welch, W.R.; Hecht, J.L. Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas. Cancer Res. 2005, 65, 2162-2169.
    • (2005) Cancer Res , vol.65 , pp. 2162-2169
    • Drapkin, R.1    von Horsten, H.H.2    Lin, Y.3    Mok, S.C.4    Crum, C.P.5    Welch, W.R.6    Hecht, J.L.7
  • 51
    • 84879409530 scopus 로고    scopus 로고
    • Evaluation of HE4 as an extrabiomarker to CA125 to improve detection of ovarian carcinoma: Is it time for a step forward?
    • in press
    • Azzam, A.Z.; Hashad, D.I.; Kamel, N.A. Evaluation of HE4 as an extrabiomarker to CA125 to improve detection of ovarian carcinoma: Is it time for a step forward? Arch. Gynecol. Obstet. 2013, in press.
    • (2013) Arch. Gynecol. Obstet
    • Azzam, A.Z.1    Hashad, D.I.2    Kamel, N.A.3
  • 53
  • 56
    • 64649105107 scopus 로고    scopus 로고
    • Development and validation of a protein-based signature for the detection of ovarian cancer
    • Kim, K.; Visintin, I.; Alvero, A.B.; Mor, G. Development and validation of a protein-based signature for the detection of ovarian cancer. Clin. Lab. Med. 2009, 29, 47-55.
    • (2009) Clin. Lab. Med , vol.29 , pp. 47-55
    • Kim, K.1    Visintin, I.2    Alvero, A.B.3    Mor, G.4
  • 58
    • 85040711538 scopus 로고    scopus 로고
    • Investigation of human cationic antimicrobial protein-18 (hCAP-18), lactoferrin and CD163 as potential biomarkers for ovarian cancer
    • Lim, R.; Lappas, M.; Riley, C.; Borregaard, N.; Moller, H.J.; Ahmed, N.; Rice, G.E. Investigation of human cationic antimicrobial protein-18 (hCAP-18), lactoferrin and CD163 as potential biomarkers for ovarian cancer. J. Ovarian Res. 2013, 6, 5.
    • (2013) J. Ovarian Res , vol.6 , pp. 5
    • Lim, R.1    Lappas, M.2    Riley, C.3    Borregaard, N.4    Moller, H.J.5    Ahmed, N.6    Rice, G.E.7
  • 59
    • 83855160925 scopus 로고    scopus 로고
    • Proteomic biomarkers in combination with CA 125 for detection of epithelial ovarian cancer using prediagnostic serum samples from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial
    • 191-100
    • Moore, L.E.; Pfeiffer, R.M.; Zhang, Z.; Lu, K.H.; Fung, E.T.; Bast, R.C., Jr. Proteomic biomarkers in combination with CA 125 for detection of epithelial ovarian cancer using prediagnostic serum samples from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial. Cancer 2012, 118, 191-100.
    • (2012) Cancer , vol.118
    • Moore, L.E.1    Pfeiffer, R.M.2    Zhang, Z.3    Lu, K.H.4    Fung, E.T.5    Bast Jr., R.C.6
  • 60
    • 84862878412 scopus 로고    scopus 로고
    • The ovarian cancer-derived secretory/releasing proteome: A repertoire of tumor markers
    • Zhang, Y.; Xu, B.; Liu, Y.; Yao, H.; Lu, N.; Li, B.; Gao, J.; Guo, S.; Han, N.; Qi, J. et al. The ovarian cancer-derived secretory/releasing proteome: A repertoire of tumor markers. Proteomics 2012, 12, 1883-1891.
    • (2012) Proteomics , vol.12 , pp. 1883-1891
    • Zhang, Y.1    Xu, B.2    Liu, Y.3    Yao, H.4    Lu, N.5    Li, B.6    Gao, J.7    Guo, S.8    Han, N.9    Qi, J.10
  • 61
    • 85128759053 scopus 로고    scopus 로고
    • A list of candidate cancer biomarkers for targeted proteomics
    • Polanski, M.; Anderson, N.L. A list of candidate cancer biomarkers for targeted proteomics. Biomark. Insights 2007, 1, 1-48.
    • (2007) Biomark. Insights , vol.1 , pp. 1-48
    • Polanski, M.1    Anderson, N.L.2
  • 64
    • 78650328715 scopus 로고    scopus 로고
    • The road from discovery to clinical diagnostics: Lessons learned from the first FDA-cleared in vitro diagnostic multivariate index assay of proteomic biomarkers
    • Zhang, Z.; Chan, D.W. The road from discovery to clinical diagnostics: lessons learned from the first FDA-cleared in vitro diagnostic multivariate index assay of proteomic biomarkers. Cancer Epidemiol. Biomarkers Prev. 2010, 19, 2995-2999.
    • (2010) Cancer Epidemiol. Biomarkers Prev , vol.19 , pp. 2995-2999
    • Zhang, Z.1    Chan, D.W.2
  • 65
    • 75749101060 scopus 로고    scopus 로고
    • A recipe for proteomics diagnostic test development: The OVA1 test, from biomarker discovery to FDA clearance
    • Fung, E.T. A recipe for proteomics diagnostic test development: the OVA1 test, from biomarker discovery to FDA clearance. Clin. Chem. 2010, 56, 327-329.
    • (2010) Clin. Chem , vol.56 , pp. 327-329
    • Fung, E.T.1
  • 69
    • 34147150867 scopus 로고    scopus 로고
    • Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17--demethoxygeldanamycin
    • Maloney, A.; Clarke, P.A.; Naaby-Hansen, S.; Stein, R.; Koopman, J.O.; Akpan, A.; Yang, A.; Zvelebil, M.; Cramer, R.; Stimson, L. et al. Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17--demethoxygeldanamycin. Cancer Res. 2007, 67, 3239-3253.
    • (2007) Cancer Res , vol.67 , pp. 3239-3253
    • Maloney, A.1    Clarke, P.A.2    Naaby-Hansen, S.3    Stein, R.4    Koopman, J.O.5    Akpan, A.6    Yang, A.7    Zvelebil, M.8    Cramer, R.9    Stimson, L.10
  • 70
    • 77956262516 scopus 로고    scopus 로고
    • Making the best of PARP inhibitors in ovarian cancer
    • Banerjee, S.; Kaye, S.B.; Ashworth, A. Making the best of PARP inhibitors in ovarian cancer. Nat. Rev. Clin. Oncol. 2010, 7, 508-519.
    • (2010) Nat. Rev. Clin. Oncol , vol.7 , pp. 508-519
    • Banerjee, S.1    Kaye, S.B.2    Ashworth, A.3
  • 71
    • 84865519032 scopus 로고    scopus 로고
    • Poly (ADP-ribose) polymerase inhibitors: On the horizon of tailored and personalized therapies for epithelial ovarian cancer
    • Ratner, E.S.; Sartorelli, A.C.; Lin, Z.P. Poly (ADP-ribose) polymerase inhibitors: on the horizon of tailored and personalized therapies for epithelial ovarian cancer. Curr. Opin. Oncol. 2012, 24, 564-571.
    • (2012) Curr. Opin. Oncol , vol.24 , pp. 564-571
    • Ratner, E.S.1    Sartorelli, A.C.2    Lin, Z.P.3


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