Aberrant free radical biology is a unifying theme in the etiology and pathogenesis of major human diseases

International Journal of Molecular Sciences

Volumn 14, Issue 4, 2013, Pages 8491-8495

  Domann, Frederick E ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Aging; Cancer; Diabetes; Free radicals; Mitochondria; Neurodegenerative disease; Nitric oxide; Oxidative stress; Reactive oxygen; Vascular disease

Indexed keywords

NITRIC OXIDE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; FREE RADICAL;

ARTICLE; CELL HYPOXIA; CEREBROVASCULAR DISEASE; DEGENERATIVE DISEASE; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDOPLASMIC RETICULUM STRESS; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; HUMAN; INTRACELLULAR SIGNALING; LIPID PEROXIDATION; LYMPHOMA; MALIGNANT NEOPLASTIC DISEASE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; STEM CELL NICHE; VASCULAR DISEASE; AGING; DISEASE; METABOLISM; MITOCHONDRION;

AGING; DISEASE; FREE RADICALS; HUMANS; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES;

EID: 84877067524     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms14048491     Document Type: Article

References (24)

1. Lin, C.-S.; Lee, H.-T.; Lee, S.-Y.; Shen, Y.-A.; Wang, L.-S.; Chen, Y.-J.; Wei, Y.-H. High mitochondrial DNA copy number and bioenergetic function are associated with tumor invasion of esophageal squamous cell carcinoma cell lines. Int. J. Mol. Sci. 2012, 13, 11228-11246.
2. Wilkinson, S.T.; Tome, M.E.; Briehl, M.M. Mitochondrial adaptations to oxidative stress confer resistance to apoptosis in lymphoma cells. Int. J. Mol. Sci. 2012, 13, 10212-10228.
3. Sharma, S.; Sun, X.; Agarwal, S.; Rafikov, R.; Dasarathy, S.; Kumar, S.; Black, S. Role of carnitine acetyl transferase in regulation of nitric oxide signaling in pulmonary arterial endothelial cells. Int. J. Mol. Sci. 2013, 14, 255-272.
4. Tomassoni, D.; Amenta, F.; Amantini, C.; Farfariello, V.; di Cesare Mannelli, L.; Nwankwo, I.; Marini, C.; Tayebati, S. Brain activity of thioctic acid enantiomers: In vitro and in vivo studies in an animal model of cerebrovascular injury. Int. J. Mol. Sci. 2013, 14, 4580-4595.
5. Xie, X.; Zhao, R.; Shen, G. Impact of cyanidin-3-glucoside on glycated ldl-induced nadph oxidase activation, mitochondrial dysfunction and cell viability in cultured vascular endothelial cells. Int. J. Mol. Sci. 2012, 13, 15867-15880.
6. De M. Bandeira, S.; da Fonseca, L.; da S. Guedes, G.; Rabelo, L.; Goulart, M.; Vasconcelos, S. Oxidative stress as an underlying contributor in the development of chronic complications in diabetes mellitus. Int. J. Mol. Sci. 2013, 14, 3265-3284.
7. Kumar, H.; Lim, H.-W.; More, S.V.; Kim, B.-W.; Koppula, S.; Kim, I.S.; Choi, D.-K. The role of free radicals in the aging brain and parkinson's disease: Convergence and parallelism. Int. J. Mol. Sci. 2012, 13, 10478-10504.
8. Lee, H.-T.; Lin, C.-S.; Chen, W.-S.; Liao, H.-T.; Tsai, C.-Y.; Wei, Y.-H. Leukocyte mitochondrial DNA alteration in systemic lupus erythematosus and its relevance to the susceptibility to lupus nephritis. Int. J. Mol. Sci. 2012, 13, 8853-8868.
9. Cardenas-Rodriguez, N.; Huerta-Gertrudis, B.; Rivera-Espinosa, L.; Montesinos-Correa, H.; Bandala, C.; Carmona-Aparicio, L.; Coballase-Urrutia, E. Role of oxidative stress in refractory epilepsy: Evidence in patients and experimental models. Int. J. Mol. Sci. 2013, 14, 1455-1476.
10. Fischer, S.; Perez, R.; Nouta, J.; Zuurmond, W.; Scheffer, P. Oxidative stress in CRPS: No systemically elevated levels of malondialdehyde, F2-isoprostanes and 8OHdG in a selected sample of patients. Int. J. Mol. Sci. 2103, 14, 7784-7794.
11. Qi, Z.; Zhang, Y.; Guo, W.; Ji, L.; Ding, S. Increased insulin sensitivity and distorted mitochondrial adaptations during muscle unloading. Int. J. Mol. Sci. 2012, 13, 16971-16985.
12. Bhandary, B.; Marahatta, A.; Kim, H.-R.; Chae, H.-J. An involvement of oxidative stress in endoplasmic reticulum stress and its associated diseases. Int. J. Mol. Sci. 2013, 14, 434-456.
13. Kong, S.-S.; Liu, J.-J.; Yu, X.-J.; Lu, Y.; Zang, W.-J. Protection against ischemia-induced oxidative stress conferred by vagal stimulation in the rat heart: Involvement of the AMPK-PKC pathway. Int. J. Mol. Sci. 2012, 13, 14311-14325.
14. Percário, S.; Moreira, D.; Gomes, B.; Ferreira, M.; Gonçalves, A.; Laurindo, P.; Vilhena, T.; Dolabela, M.; Green, M. Oxidative stress in malaria. Int. J. Mol. Sci. 2012, 13, 16346-16372.
15. Pogue, A.I.; Jones, B.M.; Bhattacharjee, S.; Percy, M.E.; Zhao, Y.; Lukiw, W.J. Metal-sulfate induced generation of ros in human brain cells: Detection using an isomeric mixture of 5- and 6-carboxy-2',7'-dichlorofluorescein diacetate (carboxy-DCFDA) as a cell permeant tracer. Int. J. Mol. Sci. 2012, 13, 9615-9626.
16. Gamba, J.; Gamba, L.; Rodrigues, G.; Kiyomoto, B.; Moraes, C.; Tengan, C. Nitric oxide synthesis is increased in cybrid cells with m.3243A>G mutation. Int. J. Mol. Sci. 2013, 14, 394-410.
17. Tengan, C.; Rodrigues, G.; Godinho, R. Nitric oxide in skeletal muscle: Role on mitochondrial biogenesis and function. Int. J. Mol. Sci. 2012, 13, 17160-17184.
18. Chen, S.-H.; Chiu, S.-J.; Hu, T.-M. Superoxide dismutase as a novel macromolecular nitric oxide carrier: Preparation and characterization. Int. J. Mol. Sci. 2012, 13, 13985-14001.
19. Cosentino-Gomes, D.; Rocco-Machado, N.; Meyer-Fernandes, J.R. Cell signaling through protein kinase C oxidation and activation. Int. J. Mol. Sci. 2012, 13, 10697-10721.
20. Berniakovich, I.; Giorgio, M. Low oxygen tension maintains multipotency, whereas normoxia increases differentiation of mouse bone marrow stromal cells. Int. J. Mol. Sci. 2013, 14, 2119-2134.
21. Milisav, I.; Poljsak, B.; Šuput, D. Adaptive response, evidence of cross-resistance and its potential clinical use. Int. J. Mol. Sci. 2012, 13, 10771-10806.
22. Lizcano, L.J.; Viloria-Bernal, M.; Vicente, F.; Berrueta, L.A.; Gallo, B.; Martínez-Cañamero, M.; Ruiz-Larrea, M.B.; Ruiz-Sanz, J.I. Lipid oxidation inhibitory effects and phenolic composition of aqueous extracts from medicinal plants of colombian amazonia. Int. J. Mol. Sci. 2012, 13, 5454-5467.
23. Uusitalo, L.M.; Hempel, N. Recent advances in intracellular and in vivo ROS sensing: Focus on nanoparticle and nanotube applications. Int. J. Mol. Sci. 2012, 13, 10660-10679.
24. Xu, Y.; Gu, Y.; Qian, S. An advanced electron spin resonance (ESR) spin-trapping and LC/(ESR)/MS technique for the study of lipid peroxidation. Int. J. Mol. Sci. 2012, 13, 14648-14666.