TgGRA23, a novel Toxoplasma gondii dense granule protein associated with the parasitophorous vacuole membrane and intravacuolar network

Parasitology International

Volumn 62, Issue 4, 2013, Pages 372-379

  Masatani, Tatsunori ^a   Matsuo, Tomohide ^b   Tanaka, Tetsuya ^b   Terkawi, Mohamad Alaa ^a   Lee, Eung Goo ^a   Goo, Youn Kyoung ^a   Aboge, Gabriel Oluga ^a   Yamagishi, Junya ^a   Hayashi, Kei ^a   Kameyama, Kyohko ^a   Cao, Shinuo ^a   Nishikawa, Yoshifumi ^a   Xuan, Xuenan ^a  

^a OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Dense granule; Intravacuolar network; Parasitophorous vacuole; Parasitophorous vacuole membrane; TgGRA23; Toxoplasma gondii

Indexed keywords

GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; POLYCLONAL; POLYCLONAL ANTISERUM; PROTOZOAL PROTEIN; RECOMBINANT PROTEIN; TGGRA23 PROTEIN; TGGRA4 PROTEIN; TGGRA7 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL LYSATE; CELL MEMBRANE; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; HYDROPHILICITY; IMMUNOBLOTTING; IMMUNOELECTRON MICROSCOPY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PARASITOPHOROUS VACUOLE MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SARCOCYSTIS; TOXOPLASMA GONDII; TOXOPLASMOSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, PROTOZOAN; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; GLUTATHIONE TRANSFERASE; IMMUNE SERA; MICE; MICE, INBRED ICR; PROTOZOAN PROTEINS; RABBITS; RECOMBINANT FUSION PROTEINS; SECRETORY VESICLES; SEQUENCE ALIGNMENT; TOXOPLASMA; TOXOPLASMOSIS; VACUOLES; VERO CELLS;

ESCHERICHIA COLI; MUS; ORYCTOLAGUS CUNICULUS; PROTOZOA; SARCOCYSTIS MURIS; TOXOPLASMA; TOXOPLASMA GONDII;

EID: 84877047062     PISSN: 13835769     EISSN: 18730329     Source Type: Journal    
DOI: 10.1016/j.parint.2013.04.003     Document Type: Article

References (30)

1. Hill D.E., Chirukandoth S., Dubey J.P. Biology and epidemiology of Toxoplasma gondii in man and animals. Animal Health Research Reviews 2005, 6:41-61.
2. Vallochi A.L., Nakamura M.V., Schlesinger D., Martins M.C., Silveira C., Belfort R., et al. Ocular toxoplasmosis: more than just what meets the eye. Scandinavian Journal of Immunology 2002, 55:324-328.
3. Cesbron-Delauw M.F., Gendrin C., Travier L., Ruffiot P., Mercier C. Apicomplexa in mammalian cells: trafficking to the parasitophorous vacuole. Traffic 2008, 9:657-664.
4. Soldati D., Dubremetz J.F., Lebrun M. Microneme proteins: structural and functional requirements to promote adhesion and invasion by the apicomplexan parasite Toxoplasma gondii. International Journal of Parasitology 2001, 31:1293-1302.
5. Bradley P.J., Sibley L.D. Rhoptries: an arsenal of secreted virulence factors. Current Opinion in Microbiology 2007, 10:582-587.
6. Mercier C., Adjogble K.D., Daubener W., Delauw M.F. Dense granules: are they key organelles to help understand the parasitophorous vacuole of all Apicomplexa parasites?. International Journal of Parasitology 2005, 35:829-849.
7. Nam H.W. GRA proteins of Toxoplasma gondii: maintenance of host-parasite interactions across the parasitophorous vacuolar membrane. The Korean Journal of Parasitology 2009, 47:S29-S37.
8. Rosowski E.E., Lu D., Julien L., Gaiser R.A., Jensen K.D., Saeij J.P. Strain-specific activation of the NF-kB pathway by GRA15, a novel Toxoplasma gondii dense granule protein. The Journal of Experimental Medicine 2011, 208:195-212.
9. Hsiao C.H., Luisa Hiller N., Haldar K., Knoll L.J. A HT/PEXEL motif in Toxoplasma dense granule proteins is a signal for protein cleavage but not export into the host cell. Traffic 2013, 14:519-531.
10. Golkar M., Rafati S., Abdel-Latif M.S., Brenier-Pinchart M.P., Fricker-Hidalgo H., Sima B.K., et al. The dense granule protein GRA2, a new marker for the serodiagnosis of acute Toxoplasma infection: comparison of sera collected in both France and Iran from pregnant women. Diagnostic Microbiology and Infectious Disease 2007, 58:419-426.
11. Sousa S., Ajzenberg D., Vilanova M., Costa J., Dardé M.L. Use of GRA6-derived synthetic polymorphic peptides in an immunoenzymatic assay to serotype Toxoplasma gondii in human serum samples collected from three continents. Clinical and Vaccine Immunology 2008, 15:1380-1386.
12. Golkar M., Azadmanesh K., Khalili G., Khoshkholgh-Sima B., Babaie J., Mercier C., et al. Serodiagnosis of recently acquired Toxoplasma gondii infection in pregnant women using enzyme-linked immunosorbent assays with a recombinant dense granule GRA6 protein. Diagnostic Microbiology and Infectious Disease 2008, 61:31-39.
13. Pietkiewicz H., Hiszczyńska-Sawicka E., Kur J., Petersen E., Nielsen H.V., Stankiewicz M., et al. Usefulness of Toxoplasma gondii-specific recombinant antigens in serodiagnosis of human toxoplasmosis. Journal of Clinical Microbiology 2004, 42:1779-1781.
14. Velmurugan G.V., Tewari A.K., Rao J.R., Baidya S., Kumar M.U., Mishra A.K. High- level expression of SAG1 and GRA7 gene of Toxoplasma gondii (Izatnagar isolate) and their application in serodiagnosis of goat toxoplasmosis. Veterinary Parasitology 2008, 154:185-192.
15. Pfrepper K.I., Enders G., Gohl M., Krczal D., Hlobil H., Wassenberg D., et al. Seroreactivity to and avidity for recombinant antigens in toxoplasmosis. Clinical and Diagnostic Laboratory Immunology 2005, 12:977-982.
16. Koethe M., Pott S., Ludewig M., Bangoura B., Zöller B., Daugschies A., et al. Prevalence of specific IgG-antibodies against Toxoplasma gondii in domestic turkeys determined by kinetic ELISA based on recombinant GRA7 and GRA8. Veterinary Parasitology 2011, 180:179-190.
17. Freyer B., Eschenbacher K.H., Mehlhorn H., Rueger W. Isolation and characterization of cDNA clones encoding a 32-kDa dense-granule antigen of Sarcocystis muris (Apicomplexa). Parasitology Research 1998, 84:583-589.
18. Jia H., Nishikawa Y., Luo Y., Yamagishi J., Sugimoto C., Xuan X. Characterization of a leucine aminopeptidase from Toxoplasma gondii. Molecular and Biochemical Parasitology 2010, 170:1-6.
19. Zhang G., Huong V.T., Battur B., Zhou J., Zhang H., Liao M., et al. A heterologous prime-boost vaccination regime using DNA and a vaccinia virus, both expressing GRA4, induced protective immunity against Toxoplasma gondii infection in mice. Parasitology 2007, 134:1339-1346.
20. Zhang H., Compaore M.K., Lee E.G., Liao M., Zhang G., Sugimoto C., et al. Apical membrane antigen 1 is a cross-reactive antigen between Neospora caninum and Toxoplasma gondii, and the anti-NcAMA1 antibody inhibits host cell invasion by both parasites. Molecular and Biochemical Parasitology 2007, 151:205-212.
21. Yu L., Yamagishi J., Zhang S., Jin C., Aboge G.O., Zhang H., et al. Protective effect of a prime-boost strategy with plasmid DNA followed by recombinant adenovirus expressing TgAMA1 as vaccines against Toxoplasma gondii infection in mice. Parasitology International 2012, 61:481-486.
22. Ueno A., Dautu G., Munyaka B., Carmen G., Kobayashi Y., Igarashi M. Toxoplasma gondii: identification and characterization of bradyzoite-specific deoxyribose phosphate aldolase-like gene (TgDPA). Experimental Parasitology 2009, 121:55-63.
23. Ibrahim H.M., Bannai H., Xuan X., Nishikawa Y. Toxoplasma gondii cyclophilin 18-mediated production of nitric oxide induces Bradyzoite conversion in a CCR5-dependent manner. Infection and Immunity 2009, 77:3686-3695.
24. Adjogble K.D., Mercier C., Dubremetz J.F., Hucke C., Mackenzie C.R., et al. GRA9, a new Toxoplasma gondii dense granule protein associated with the intravacuolar network of tubular membranes. International Journal of Parasitology 2004, 34:1255-1264.
25. Carruthers V.B., Sibley L.D. Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblast. European Journal of Cell Biology 1997, 73:114-123.
26. Sibley L.D., Niesman I.R., Parmeley S.F., Cesbron-Delauw M.F. Regulated secretion of multi-lamellar vesicles leads to formation of a tubulo-vesicular network in host-cell vacuoles occupied by Toxoplasma gondii. Journal of Cell Science 1995, 108:1669-1677.
27. Luo Y., Jia H., Terkawi M.A., Goo Y.K., Kawano S., Ooka H., et al. Identification and characterization of a novel secreted antigen 1 of Babesia microti and evaluation of its potential use in enzyme-linked immunosorbent assay and immunochromatographic test. Parasitology International 2011, 60:119-125.
28. Goo Y.K., Jia H., Aboge G.O., Terkawi M.A., Kuriki K., Nakamura C., et al. Babesia gibsoni: serodiagnosis of infection in dogs by an enzyme-linked immunosorbent assay with recombinant BgTRAP. Experimental Parasitology 2008, 118:555-560.
29. Burg J.L., Perelman D., Kasper L.H., Ware P.L., Boothroyd J.C. Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii. Journal of Immunology 1988, 141:3584-3591.
30. Neudeck A., Stachelhaus S., Nischik N., Striepen B., Reichmann G., Fischer H.G. Expression variance, biochemical and immunological properties of Toxoplasma gondii dense granule protein GRA7. Microbes and Infection 2002, 4:581-590.