The dense granule protein GRA2, a new marker for the serodiagnosis of acute Toxoplasma infection: comparison of sera collected in both France and Iran from pregnant women

Diagnostic Microbiology and Infectious Disease

Volumn 58, Issue 4, 2007, Pages 419-426

  Golkar, Majid ^a,b   Rafati, Sima ^b   Abdel Latif, Mohamed S ^a,c   Brenier Pinchart, Marie Pierre ^a,d   Fricker Hidalgo, Hélène ^d   Sima, Baharak Khoshkholgh ^b   Babaie, Jalal ^b   Pelloux, Hervé ^a,d   Cesbron Delauw, Marie France ^a   Mercier, Corinne ^a  

^a CNRS   (France)

^b PASTEUR INSTITUTE OF IRAN   (Iran)

^c ALEXANDRIA UNIVERSITY   (Egypt)

^d GRENOBLE UNIVERSITY HOSPITAL   (France)

Author keywords

Dense granule; Parasite; pET vector; Serologic diagnosis; Thioredoxin; Toxoplasma gondii

Indexed keywords

ANTIGEN; BIOLOGICAL MARKER; DENSE GRANULE ANTIGEN 2; HYBRID PROTEIN; UNCLASSIFIED DRUG;

ACUTE DISEASE; ARTICLE; BLOOD SAMPLING; CHRONIC DISEASE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FRANCE; HUMAN; IMMUNOBLOTTING; IMMUNOREACTIVITY; IRAN; PREGNANT WOMAN; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SERODIAGNOSIS; TOXOPLASMOSIS;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FRANCE; HUMANS; IMMUNOGLOBULIN G; IRAN; PREGNANT WOMEN; PROTOZOAN PROTEINS; RECOMBINANT FUSION PROTEINS; SENSITIVITY AND SPECIFICITY; SEROLOGIC TESTS; TOXOPLASMA; TOXOPLASMOSIS;

EID: 34547575468     PISSN: 07328893     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2007.03.003     Document Type: Article

References (28)

1. Altcheh J., Diaz N.S., Pepe C.M., Martin V., Nigro M., Freilij H., and Angel S.O. Kinetic analysis of the humoral immune response against three Toxoplasma gondii-recombinant proteins in infants with suspected congenital toxoplasmosis. Diagn. Microbiol. Infect. Dis. 56 (2006) 161-165
2. Aubert D., Maine G.T., Villena I., Hunt J.C., Howard L., Sheu M., Brojanac S., Chovan L.E., Nowlan S.F., and Pinon J.M. Recombinant antigens to detect Toxoplasma gondii-specific immunoglobulin G and immunoglobulin M in human sera by enzyme immunoassay. J. Clin. Microbiol. 38 (2000) 1144-1150
3. Beghetto E., Buffolano W., Spadoni A., Del Pezzo M., Di Cristina M., Minenkova O., Petersen E., Felici F., and Gargano N. Use of an immunoglobulin G avidity assay based on recombinant antigens for diagnosis of primary Toxoplasma gondii infection during pregnancy. J. Clin. Microbiol. 41 (2003) 5414-5418
4. Beghetto E., Spadoni A., Bruno L., Buffolano W., and Gargano N. Chimeric antigens of Toxoplasma gondii; toward standardization of toxoplasmosis serodiagnosis using recombinant products. J. Clin. Microbiol. 44 (2006) 2133-2140
5. Brinkmann V., Remington J.S., and Sharma S.D. Vaccination of mice with the protective F3G3 antigen of Toxoplasma gondii activates CD4+ but not CD8+ cells and induces Toxoplasma specific IgG antibody. Mol. Immunol. 30 (1993) 353-358
6. Buffolano W., Beghetto E., Del Pezzo M., Spadoni A., Di Cristina M., Petersen E., and Gargano N. Use of recombinant antigens for early postnatal diagnosis of congenital toxoplasmosis. J. Clin. Microbiol. 43 (2005) 5916-5924
7. Ferrandiz J., Mercier C., Wallon M., Picot S., Cesbron-Delauw M.F., and Peyron F. Limited value of assays using detection of immunoglobulin G antibodies to the two recombinant dense granule antigens, GRA1 and GRA6 Nt of Toxoplasma gondii, for distinguishing between acute and chronic infections in pregnant women. Clin. Diagn. Lab. Immunol. 11 (2004) 1016-1021
8. Fricker-Hidalgo H., Saddoux C., Suchel-Jambon A.S., Romand S., Foussadier A., Pelloux H., and Thulliez P. New Vidas assay for Toxoplasma-specific IgG avidity, evaluation on 603 sera. Diagn. Microbiol. Infect. Dis. (2006) [Online May 23]
9. Gatkowska J., Hiszczynska-Sawicka E., Kur J., Holec L., and Dlugonska H. Toxoplasma gondii, an evaluation of diagnostic value of recombinant antigens in a murine model. Exp. Parasitol. 114 (2006) 220-227
10. Golkar M., Rafati S., Taslimi Y., Taheri T., Doustdari F., and Assmar M. High-level expression and evaluation of the antigenicity of a recombinant Toxoplasma gondii GRA2 protein. Iranian J. Biotech. 2 (2004) 170-176
11. Hughes H.P., and van Knapen F. Characterisation of a secretory antigen from Toxoplasma gondii and its role in circulating antigen production. Int. J. Parasitol. 12 (1982) 433-437
12. Jacobs D., Vercammen M., and Saman E. Evaluation of recombinant dense granule antigen 7 (GRA7) of Toxoplasma gondii for detection of immunoglobulin G antibodies and analysis of a major antigenic domain. Clin. Diagn. Lab. Immunol. 6 (1999) 24-29
13. Lecordier L., Fourmaux M.P., Mercier C., Dehecq E., Masy E., and Cesbron-Delauw M.F. Enzyme-linked immunosorbent assays using the recombinant dense granule antigens GRA6 and GRA1 of Toxoplasma gondii for detection of immunoglobulin G antibodies. Clin. Diagn. Lab. Immunol. 7 (2000) 607-611
14. Li S., Galvan G., Araujo F.G., Suzuki Y., Remington J.S., and Parmley S. Serodiagnosis of recently acquired Toxoplasma gondii infection using an enzyme-linked immunosorbent assay with a combination of recombinant antigens. Clin. Diagn. Lab. Immunol. 7 (2000) 781-787
15. Makrides S.C. Strategies for achieving high-level expression of genes in Escherichia coli. Microbiol Rev. 60 (1996) 512-538
16. Mercier C., Cesbron-Delauw M.F., and Ferguson D.J.P. Dense granules of the infectious stages of Toxoplasma gondii: their central role in the host/parasite relationship. In: Soldati D., and Ajioka J. (Eds). Toxoplasma: Molecular and Cellular Biology (2007), Horizon Scientific Press [In press]
17. Mercier C., Lecordier L., Darcy F., Deslée D., Murray A., Tourvieille B., Maes P., Capron A., and Cesbron-Delauw M.F. Toxoplasma gondii: molecular characterization of a dense granule antigen (GRA2) associated with the network of the parasitophorous vacuole. Mol. Biochem. Parasitol. 58 (1993) 71-82
18. Montoya J.G., and Rosso F. Diagnosis and management of toxoplasmosis. Clin. Perinatol. 32 (2005) 705-726
19. Murray A., Mercier C., Decoster A., Lecordier L., Capron A., and Cesbron-Delauw M.F. Multiple B-cell epitopes in a recombinant GRA2 secreted antigen of Toxoplasma gondii. Appl. Parasitol. 34 (1993) 235-244
20. Nigro M., Gutierrez A., Hoffer A.M., Clemente M., Kaufer F., Carral L., Martin V., Guarnera E.A., and Angel S.O. Evaluation of Toxoplasma gondii recombinant proteins for the diagnosis of recently acquired toxoplasmosis by an immunoglobulin G analysis. Diagn. Microbiol. Infect. Dis. 47 (2003) 609-613
21. Parmley S.F., Sgarlato G.D., and Remington J.S. Genomic and corrected cDNA sequence of the P28 gene from Toxoplasma gondii. Mol. Biochem. Parasitol. 57 (1993) 161-166
22. Parmley S.F., Sgarlato G.D., Mark J., Prince J.B., and Remington J.S. Expression, characterization and serologic reactivity of recombinant surface antigen P22 of Toxoplasma gondii. J. Clin. Microbiol. 30 (1992) 1127-1133
23. Pfrepper K.I., Enders G., Gohl M., Krczal D., Hlobil H., Wassenberg D., and Soutschek E. Seroreactivity to and avidity for recombinant antigens in toxoplasmosis. Clin. Diagn. Lab. Immunol. 12 (2005) 977-982
24. Pietkiewicz H., Hiszczynska-Sawicka E., Kur J., Petersen E., Nielsen H.V., Stankiewicz M., Andrzejewska I., and Myjak P. Usefulness of Toxoplasma gondii-specific recombinant antigens in serodiagnosis of human toxoplasmosis. J. Clin. Microbiol. 42 (2004) 1779-1781
25. Prigione I., Facchetti P., Lecordier L., Deslée D., Chiesa S., Cesbron-Delauw M.F., and Pistoia V. T cell clones raised from chronically infected healthy humans by stimulation with Toxoplasma gondii excretory-secretory antigens cross-react with live tachyzoites: characterization of the fine antigenic specificity of the clones and implications for vaccine development. J. Immunol. 164 (2000) 3741-3748
26. Redlich A., and Muller W.A. Serodiagnosis of acute toxoplasmosis using a recombinant form of the dense granule antigen GRA6 in an enzyme-linked immunosorbent assay. Parasitol. Res. 84 (1998) 700-706
27. Reiter-Owona I., Petersen E., Joynson D., Aspöck H., Dardé M.L., Disko R., Dreazen O., Dumon H., Grillot R., Gross U., Hayde M., Holliman R., Ho-Yen D.O., Janitschke K., Jenum P.A., Naser K., Olszewski M., Thulliez P., and Seitz H.M. The past and present role of the Sabin-Feldman dye test in the serodiagnosis of toxoplasmosis. Bull. World Health Organ. 77 (1999) 929-935
28. Sharma S.D., Araujo F.G., and Remington J.S. Toxoplasma antigen isolated by affinity chromatography with monoclonal antibody protects mice against lethal infection with Toxoplasma gondii. J. Immunol. 133 (1984) 2818-2820