Combination of β-cyclodextrin inclusion complex and self-microemulsifying drug delivery system for photostability and enhanced oral bioavailability of methotrexate: Novel technique

Drug Development and Industrial Pharmacy

Volumn 39, Issue 6, 2013, Pages 918-927

  Bourkaib, Nadia ^a   Zhou, Jianping ^a   Yao, Jing ^a   Fang, Zhengjie ^a   Mezghrani, Omar ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

CD; Bioavailability; Inclusion complex; MTX; Photostability; SMEDDS

Indexed keywords

BETA CYCLODEXTRIN; METHOTREXATE; OLEIC ACID ETHYL ESTER; POLYSORBATE 80; PROPYLENE GLYCOL;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; FREEZE DRYING; IN VITRO STUDY; INFRARED SPECTROSCOPY; LIGHT EXPOSURE; NONHUMAN; PH; PHOTOSENSITIVITY; RAT; ULTRAVIOLET RADIATION;

ADMINISTRATION, ORAL; ANIMALS; BETA-CYCLODEXTRINS; BIOLOGICAL AVAILABILITY; DRUG COMBINATIONS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; EMULSIFYING AGENTS; METHOTREXATE; PHOTIC STIMULATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84877045119     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2012.718785     Document Type: Article

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