Structural neuroplastic change after constraint-induced movement therapy in children with cerebral palsy

Pediatrics

Volumn 131, Issue 5, 2013, Pages

  Sterling, Chelsey ^a   Taub, Edward ^a   Davis, Drew ^a   Rickards, Tyler ^a   Gauthier, Lynne V ^b   Griffin, Angi ^c   Uswatte, Gitendra ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c Physical Therapy and Occupational Therapy Department   (United States)

Author keywords

Cerebral palsy; Ci therapy; Hemiplegia; Neuroimaging; Neuroplasticity; Rehabilitation

Indexed keywords

ARM MOVEMENT; ARTICLE; BRAIN SIZE; CEREBRAL PALSY; CHILD; CLINICAL ARTICLE; CONSTRAINT INDUCED THERAPY; DAILY LIFE ACTIVITY; FEMALE; GRAY MATTER; HEMIPARESIS; HUMAN; MALE; MOTOR CORTEX; MOTOR PERFORMANCE; MOVEMENT THERAPY; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PEDIATRIC MOTOR ACTIVITY LOG REVISED; PILOT STUDY; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SCORING SYSTEM; SENSORIMOTOR CORTEX; THERAPY EFFECT; TREATMENT DURATION; VOXEL BASED MORPHOMETRY;

CEREBRAL PALSY; CI THERAPY; HEMIPLEGIA; NEUROIMAGING; NEUROPLASTICITY; REHABILITATION;

CEREBRAL CORTEX; CEREBRAL PALSY; CHILD; CHILD, PRESCHOOL; EXERCISE MOVEMENT TECHNIQUES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; PARESIS; PILOT PROJECTS; RECOVERY OF FUNCTION; RESTRAINT, PHYSICAL; RISK ASSESSMENT; SAMPLING STUDIES; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 84877018667     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2012-2051     Document Type: Article

References (31)

1. Taub E, Miller NE, Novack TA, et al. Technique to improve chronic motor deficit after stroke. Arch Phys Med Rehabil. 1993;74(4):347-354 (Pubitemid 23115348)
2. Taub E, Uswatte G, King DK, Morris D, Crago JE, Chatterjee A. A placebo-controlled trial of constraint-induced movement therapy for upper extremity after stroke. Stroke. 2006;37(4):1045-1049
3. Wolf SL, Winstein CJ, Miller JP, et al EXCITE Investigators. Effect of constraint-induced movement therapy on upper extremity function 3 to 9 months after stroke: the EXCITE randomized clinical trial. JAMA. 2006;296(17):2095-2104 (Pubitemid 44664704)
4. Taub E, Ramey SL, DeLuca S, Echols K. Efficacy of constraint-induced movement therapy for children with cerebral palsy with asymmetric motor impairment. Pediatrics. 2004;113(2):305-312 (Pubitemid 38177081)
5. Taub E, Griffin A, Nick J, Gammons K, Uswatte G, Law CR. Pediatric CI therapy for stroke-induced hemiparesis in young children. Dev Neurorehabil. 2007;10(1):3-18 (Pubitemid 47555466)
6. Taub E, Griffin A, Uswatte G, Gammons K, Nick J, Law CR. Treatment of congenital hemiparesis with pediatric constraint-induced movement therapy. J Child Neurol. 2011;26(9):1163-1173
7. Huang HH, Fetters L, Hale J, McBride A. Bound for success: a systematic review of constraint-induced movement therapy in children with cerebral palsy supports improved arm and hand use. Phys Ther. 2009;89(11):1126-1141
8. Kopp B, Kunkel A, Mühlnickel W, Villringer K, Taub E, Flor H. Plasticity in the motor system related to therapy-induced improvement of movement after stroke. Neuroreport. 1999;10(4):807-810 (Pubitemid 29393827)
9. Liepert J, Bauder H, Miltner WH, Taub E, Weiller C. Treatment-induced cortical reorganization after stroke in humans. Stroke. 2000;31(6):1210-1216 (Pubitemid 30351235)
10. Schaechter JD, Kraft E, Hilliard TS, et al. Motor recovery and cortical reorganization after constraint-induced movement therapy in stroke patients: a preliminary study. Neurorehabil Neural Repair. 2002;16(4):326-338 (Pubitemid 35375608)
11. Wittenberg GF, Chen R, Ishii K, et al. Constraint-induced therapy in stroke: magnetic-stimulation motor maps and cerebral activation. Neurorehabil Neural Repair. 2003;17(1):48-57 (Pubitemid 37102027)
12. Mark VW, Taub E, Morris DM. Neuroplasticity and constraint-induced movement therapy. Eura Medicophys. 2006;42(3):269-284 (Pubitemid 46030369)
13. Gauthier LV, Taub E, Perkins C, Ortmann M, Mark VW, Uswatte G. Remodeling the brain: plastic structural brain changes produced by different motor therapies after stroke. Stroke. 2008;39(5):1520-1525
14. Wallen M, Bundy A, Pont K, Ziviani J. Psychometric properties of the Pediatric Motor Activity Log used for children with cerebral palsy. Dev Med Child Neurol. 2009;51(3):200-208
15. Uswatte G, Taub E, Griffin A, Vogtle L, Rowe J, Barman J. The Pediatric Motor Activity Log-Revised: assessing real-world arm use in children with cerebral palsy. Rehabil Psychol. 2012;57(2):149-158
16. Cravero JP, Blike GT, Beach M, et al Pediatric Sedation Research Consortium. Incidence and nature of adverse events during pediatric sedation/anesthesia for procedures outside the operating room: report from the Pediatric Sedation Research Consortium. Pediatrics. 2006;118(3):1087-1096 (Pubitemid 46090050)
17. Kiringoda R, Thurm AE, Hirschtritt ME, et al. Risks of propofol sedation/anesthesia for imaging studies in pediatric research: eight years of experience in a clinical research center. Arch Pediatr Adolesc Med. 2010;164(6):554-560
18. Smith SM. Fast robust automated brain extraction. Hum Brain Mapp. 2002;17(3):143-155 (Pubitemid 35253488)
19. Wilke M, Holland SK, Altaye M, Gaser C. Template-O-Matic: a toolbox for creating customized pediatric templates. Neuroimage. 2008;41(3):903-913
20. Uswatte G, Taub E, Griffin A, Rowe J, Vogtle L, Barman J. Pediatric arm function test: reliability and validity for assessing more-affected arm motor capacity in children with cerebral palsy. Am J Phys Med Rehabil. 2012;91(12):1060-1069
21. Sutcliffe TL, Gaetz WC, Logan WJ, Cheyne DO, Fehlings DL. Cortical reorganization after modified constraint-induced movement therapy in pediatric hemiplegic cerebral palsy. J Child Neurol. 2007;22(11):1281-1287 (Pubitemid 350130643)
22. Sutcliffe TL, Logan WJ, Fehlings DL. Pediatric constraint-induced movement therapy is associated with increased contralateral cortical activity on functional magnetic resonance imaging. J Child Neurol. 2009;24(10):1230-1235
23. Mall V, Linder M, Herpers M, et al. Recruitment of the sensorimotor cortex - a developmental fMRI study. Neuropediatrics. 2005;36(6):373-379 (Pubitemid 43162348)
24. Carr LJ, Harrison LM, Evans AL, Stephens JA. Patterns of central motor reorganization in hemiplegic cerebral palsy. Brain. 1993;116(pt 5):1223-1247 (Pubitemid 23329891)
25. Thickbroom GW, Byrnes ML, Archer SA, Nagarajan L, Mastaglia FL. Differences in sensory and motor cortical organization following brain injury early in life. Ann Neurol. 2001;49(3):320-327 (Pubitemid 32202785)
26. Staudt M, Grodd W, Gerloff C, Erb M, Stitz J, Krägeloh-Mann I. Two types of ipsilateral reorganization in congenital hemiparesis: a TMS and fMRI study. Brain. 2002;125(pt 10):2222-2237
27. Taub E, Pearson S, Griffin A, et al. Motor deficit following hemispherectomy treated with pediatric CI therapy: a case study, Program No. 697.4, Neuroscience 2007. Abstracts. San Diego, CA: Society for Neuroscience, 2007.
28. Briones TL, Suh E, Jozsa L, Woods J. Behaviorally induced synaptogenesis and dendritic growth in the hippocampal region following transient global cerebral ischemia are accompanied by improvement in spatial learning. Exp Neurol. 2006;198(2):530-538
29. Kolb B, Morshead C, Gonzalez C, et al. Growth factor-stimulated generation of new cortical tissue and functional recovery after stroke damage to the motor cortex of rats. J Cereb Blood Flow Metab. 2007;27(5):983-997 (Pubitemid 46659027)
30. Maier IC, Baumann K, Thallmair M, Weinmann O, Scholl J, Schwab ME. Constraint-induced movement therapy in the adult rat after unilateral corticospinal tract injury. J Neurosci. 2008;28(38):9386-9403
31. Zhao C, Wang J, Zhao S, Nie Y. Constraint-induced movement therapy enhanced neurogenesis and behavioral recovery after stroke in adult rats. Tohoku J Exp Med. 2009;218(4):301-308