INDACO project: A pilot study on incidence of comorbidities in COPD patients referred to pneumology units

Multidisciplinary Respiratory Medicine

Volumn 8, Issue 4, 2013, Pages

  Fumagalli, Giorgio ^a,f   Fabiani, Fabrizio ^b   Forte, Silvia ^b   Napolitano, Massimiliano ^c   Marinelli, Paolo ^d   Palange, Paolo ^d   Pentassuglia, Antonella ^c   Carlone, Stefano ^b   Sanguinetti, Claudio Maria ^e  

^a SAN FILIPPO NERI HOSPITAL   (Italy)

^b Hospital San Giovanni Addolorata   (Italy)

^c MOLINETTE HOSPITAL   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e Clinica Quisisana Orthopedia   (Italy)

^f UOC di Pneumologia   (Italy)

Author keywords

BMI; Charlson comorbidity index; Comorbidities; COPD; COPD exacerbation; Inhaled drug therapy; Smoking

Indexed keywords

BRONCHODILATING AGENT; CORTICOSTEROID;

ADULT; AGED; ANTHROPOMETRY; ANXIETY; ARTICLE; BODY MASS; CHARLSON COMORBIDITY INDEX; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMORBIDITY; DEPRESSION; DIABETES MELLITUS; DISEASE EXACERBATION; DISEASE SEVERITY; DYSPNEA; FEMALE; HOSPITAL; HUMAN; HYPERTENSION; INCIDENCE; ITALY; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; NEOPLASM; OUTPATIENT; PATIENT REFERRAL; PILOT STUDY; PREVALENCE; RESPIRATORY FUNCTION; SMOKING;

EID: 84876909512     PISSN: 1828695X     EISSN: 20496958     Source Type: Journal    
DOI: 10.1186/2049-6958-8-28     Document Type: Article

References (44)

1. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease (GOLD, updated 2012). Available at: http://www.goldcopd.org.
2. Barnes PJ, Celli BR: Systemic manifestations and comorbidities of COPD. Eur Respir J 2009, 33:1165-1185.
3. Donner CF (Ed): COPD is/is not a systemic disease? New York: Nova Biomedica Books; 2010.
4. Chatila WM, Thomashow BM, Minai OA, Criner GC, Make BJ: Comorbidities in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2008, 5:549-555. (Pubitemid 351669185)
5. Gan WQ, Man SF, Senthilselvan A, Sin DD: Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis. Thorax 2004, 59:574-580. (Pubitemid 38901515)
6. Sevenoaks MJ, Stockley RA: Chronic obstructive pulmonary disease, Inflammation, and co-morbidity-a common inflammatory phenotype? Respir Res 2006, 7:70.
7. Fabbri LM, Rabe KF: From COPD to chronic systemic inflammatory syndrome? Lancet 2007, 370:797-799. (Pubitemid 47320803)
8. Lange P, Mogelvang R, Marott JL, Vestbo J, Jensen JS: Cardiovascular morbidity in COPD: a study of the general population. COPD 2010, 7:5-10.
9. Holguin F, Folch E, Redd SC, Mannino DM: Comorbidity and mortality in COPD-related hospitalizations in the United States, 1979 to 2001. Chest 2005, 128:2005- 2011.
10. Mannino DM, Thorn D, Swenses A, Holguin F: Prevalence and outcomes of diabetes, hypertension, and cardiovascular disease in chronic obstructive pulmonary disease. Eur Respir J 2008, 32:962-969.
11. Foster TS, Miller JD, Marton JP, Caloyeras JP, Russell MW, Menzin J: Assessment of the economic burden of COPD in the US: a review and synthesis of the literature. COPD 2006, 3:211-218. (Pubitemid 44949061)
12. Anthonisen NR, Connett JE, Enright PL, Manfreda J: Hospitalizations and mortality in the Lung Health Study. Am J Respir Crit Care Med 2002, 166:333-339. (Pubitemid 34864422)
13. Sin DD, Anthonisen NR, Soriano JB, Agusti AG: Mortality in COPD: role of comorbidities. Eur Respir J 2006, 28:1245-1257. (Pubitemid 44883863)
14. Garcia-Sanz MT, Pol-Balado C, Abellas C, Canive-Gomez JC, Anton-Sanmartin D, Gonzalez-Barcala FJ: Factors associated with hospital admission in patients reaching the emergency department with COPD exacerbation. Multidiscip Respir Med 2012, 7:6-13.
15. Antonelli-Incalzi R, Fuso L, De Rosa M, Forastiere F, Rapiti E, Nardecchia B, Pistelli R: Co-morbidity contributes to predict mortality of patients with chronic obstructive pulmonary disease. Eur Respir J 1997, 10:2794-2800. (Pubitemid 28052790)
16. Fuso L, Incalzi RA, Pistelli R, Muzzolon R, Valente S, Pagliari G, Gliozzi F, Ciappi G: Predicting mortality of patients hospitalized for acutely exacerbated chronic obstructive pulmonary disease. Am J Med 1995, 98:272-277.
17. Van Manen JG, Bindels PJ, IJzermans CJ, van der Zee JS, Bottema BJ, Schadè E: Prevalence of comorbidity in patients with a chronic airway obstruction and controls over the age of 40. J Clin Epidemiol 2001, 54:287-293. (Pubitemid 32153871)
18. Mapel DW, Hurley JS, Frost FJ, Petersen HV, Picchi MA, Coultas DB: Health care utilization in chronic obstructive pulmonary disease: a case-control study in a health maintenance organization. Arch Intern Med 2000, 160:2653-2658.
19. Sidney S, Sorel M, Quesenberry CP Jr, DeLuise C, Lanes S, Eisner MD: COPD and incident cardiovascular disease hospitalizations and mortality: Kaiser permanente medical care program. Chest 2005, 128: 2068-2075. (Pubitemid 41507542)
20. Soriano JB, Visick GT, Muellerova H, Payvandi N, Hansell AL: Patterns of comorbidities in newly diagnosed COPD and asthma in primary care. Chest 2005, 128:2099-2107. (Pubitemid 41507547)
21. Crisafulli E, Costi S, Luppi F, Cirelli G, Cilione C, Coletti O, Fabbri LM, Clini EM: Role of comorbidities in a cohort of patients with COPD undergoing pulmonary rehabilitation. Thorax 2008, 63:487-492. (Pubitemid 351831155)
22. Feary JR, Rodriguez LC, Smith CJ, Hubbard RB, Gibson JE: Prevalence of major comorbidities in subjects with COPD and incidence of myocardial infarction and stroke: a comprehensive analysis using data from primary care. Thorax 2010. doi:10.1136/thx.2009.128082.
23. Almagro P, López García F, Cabrera FJ, Montero L, Morchon D: Comorbidity and gender-related differences in patients hospitalized for COPD. The ECCO study. Respir Med 2010, 104:253-259.
24. Cazzola M, Bettoncelli G, Sessa E, Cricelli C, Biscione G: Prevalence of comorbidities in patients with chronic obstructive pulmonary disease. Respiration 2010, 80:112-119.
25. Terzano C, Conti V, Di Stefano F, Petroianni A, Ceccarelli D, Graziani E, Mariotta S, Ricci A, Vitarelli A, Puglisi G, De Vito C, Villari P, Allegra L: Comorbidity, hospitalization, and mortality in COPD: results from a longitudinalstudy. Lung 2010, 188: 321-329.
26. Charlson ME, Pompei P, Ales KL, MacKenzie CR: A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chron Dis 1987, 40:373-383. (Pubitemid 17055592)
27. Anecchino C, Rossi E, Fanizza C, De Rosa M, Tognoni G, Romero M: Prevalence of chronic obstructive pulmonary disease and pattern of comorbidities in a general population. Int J COPD 2007, 2:567-574.
28. The Italian cardiovascular epidemiological observatory. Ital Heart J 2004, 5(suppl. 3):49S-92S.
29. Heindl S, Lehnert M, Crièe CP, Hasenfuss G, Andreas S: Marked sympathetic activation in patients with chronic respiratory failure. Am J Respir Crit Care Med 2001, 164:597-601. (Pubitemid 32801663)
30. Sin DD, Man SFP: Chronic obstructive pulmonary disease: a novel risk factor for cardiovascular disease. Can J Physiol Pharmacol 2005, 83:8-13. (Pubitemid 40754770)
31. Ridker PM: Clinical applications of C-reactive protein for cardiovascular disease detection and prevention. Circulation 2003, 107:363-369.
32. Mills NL, Miller JJ, Anand A, Robinson SD, Frazer GA, Anderson D, Breen L, Wilkinson IB, McEniery CM, Donaldson K, Newby DE, Macnee W: Increased arterial stiffness in patients with chronic obstructive pulmonary disease: a mechanism for increased cardiovascular risk. Thorax 2008, 63:306-311. (Pubitemid 351497941)
33. Johnston AK, Mannino DM, Hagan GW, Davis KJ, Kiri VA: Relationship between lung function impairment and incidence or recurrence of cardiovascular events in a middle-aged cohort. Thorax 2008, 63:599-605. (Pubitemid 351969252)
34. Ford ES, Giles WH, Dietz WH: Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 2002, 287:356-359. (Pubitemid 34251969)
35. Notarbartolo A: La sindromemetabolica in Italia: rilievi epidemiologici e clinici (Editorial, 2008). www.cardiometabolica.org; accessed january 2011.
36. Visser M, Bouter LM, McQuillan GM, Wener MH, Harris TB: Elevated Creactive protein levels in overweight and obese adults. JAMA 1999, 282:2131-2135.
37. Magnussen H, Watz H: Systemic inflammation in chronic obstructive pulmonary disease and asthma: relation with comorbidities. Proc Am Thorac Soc 2009, 6:648-651.
38. Watz H, Waschki B, Kirsten A, Muller KC, Kretschmar G, Meyer T, Holz O, Magnussen H: The metabolic syndrome in patients with chronic bronchitis and COPD: frequency and associated consequences for systemic inflammation and physical inactivity. Chest 2009, 136:1039-1046.
39. Epicentro: centronazionale di epidemiologia, sorveglianza e promozione della salute dell'Istituto Superiore di Sanità: www.epicentro.iss.it; accessed january 2011.
40. Rana JS, Mittleman MA, Sheikh J, Hu FB, Manson JE, Colditz GA, Speizer FE, Barr RG, Camargo CA Jr: Chronic obstructive pulmonary disease, asthma, and risk of type 2 diabetes in women. Diabetes Care 2004, 27:2478-2484. (Pubitemid 39281404)
41. Sonnenberg GE, Krakower GR, Kissebah AH: A novel pathway to the manifestations of metabolic syndrome. Obes Res 2004, 12: 180-186. (Pubitemid 41132540)
42. Zhang H: Molecular signaling and genetic pathways of senescence: its role in tumorigenesis and aging. J Cell Physiol 2007, 210:567-574.
43. Mannino DM, Aguayo SM, Petty TL, Redd SC: Low lung function and incident lung cancer in the United States: data from the First National Health and Nutrition Examination Survey follow-up. Arch Intern Med 2003, 163:1475-1480. (Pubitemid 36758921)
44. Yohannes AM, Baldwin RC, Connolly MJ: Depression and anxiety in elderly patients with chronic obstructive pulmonary disease. Age Ageing 2006, 35:457-459. (Pubitemid 44295630)