Amyloid positron emission tomography with 18F-flutemetamol and structural magnetic resonance imaging in the classification of mild cognitive impairment and Alzheimer's disease

Alzheimer's and Dementia

Volumn 9, Issue 3, 2013, Pages 295-301

  Duara, Ranjan ^a,b   Loewenstein, David A ^a,b   Shen, Qian ^a,b   Barker, Warren ^a   Potter, Elizabeth ^a   Varon, Daniel ^a   Heurlin, Kristen ^c   Vandenberghe, Rik ^d   Buckley, Christopher ^c  

^a MOUNT SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c GE HEALTHCARE   (United Kingdom)

^d UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Amyloid imaging; Hippocampal atrophy; MCI; MRI; PET

Indexed keywords

AMYLOID; FLUTEMETAMOL F 18;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN ATROPHY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE CLASSIFICATION; DISEASE SEVERITY; FEMALE; HUMAN; MALE; MILD COGNITIVE IMPAIRMENT; MULTICENTER STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PRODROMAL SYMPTOM; SCORING SYSTEM;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID; ANILINE COMPOUNDS; BENZOTHIAZOLES; FEMALE; HUMANS; LOGISTIC MODELS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MILD COGNITIVE IMPAIRMENT; NEOCORTEX; NEUROPSYCHOLOGICAL TESTS; POSITRON-EMISSION TOMOGRAPHY; SEVERITY OF ILLNESS INDEX;

EID: 84876898625     PISSN: 15525260     EISSN: 15525279     Source Type: Journal    
DOI: 10.1016/j.jalz.2012.01.006     Document Type: Article

References (31)

1. C.R. Jack Jr., D.S. Knopman, W.J. Jagust, L.M. Shaw, P.S. Aisen, and M.W. Weiner Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade Lancet Neurol 9 2010 119 128
2. J. Morris, C. Roe, C. Xiong, A.M. Fagan, A.M. Goate, and D.M. Holtzman APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging Ann Neurol 67 2010 122 131
3. K. Pike, G. Savage, V.L. Villemagne, S. Ng, S.A. Moss, and P. Maruff β Amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease Brain 130 2007 2837 2844
4. G. Chetelat, V.L. Villemagne, and K.E. Pike Independent contribution of temporal b-amyloid deposition to memory decline in the pre-dementia phase of Alzheimer's disease Brain 134 2011 798 807
5. C.R. Jack Jr., H.J. Wiste, P. Vemuri, S.D. Weigand, M.L. Senjem, and G. Zeng Alzheimer's Disease Neuroimaging Initiative. Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease Brain 133 2010 3336 3348
6. A. Okello, J. Koivunen, P. Edison, H.A. Archer, F.E. Turkheimer, and K. Någren Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study Neurology 73 2009 754 760
7. D. Tosun, N. Schuff, C.A. Mathis, W. Jagust, and M.W. Weiner Spatial patterns of brain amyloid-β burden and atrophy rate associations in mild cognitive impairment Brain 134 2011 1077 1088
8. C.D. Smith, H. Chebrolu, D.R. Wekstein, F.A. Schmitt, G.A. Jicha, and G. Cooper Brain structural alterations before mild cognitive impairment Neurology 68 2007 1268 1273
9. A. Convit, J. de Asis, M.J. de Leon, C.Y. Tarshish, S. De Santi, and H. Rusinek Atrophy of the medial occipitotemporal, inferior, and middle temporal gyri in non-demented elderly predict decline to Alzheimer's disease Neurobiol Aging 21 2000 19 26
10. R. Petersen, G. Smith, S. Waring, R.J. Ivnik, E.G. Tangalos, and Kokmen Mild cognitive impairment: clinical characterization and outcome Arch Neurol 56 1999 303 308
11. H. Buschke Selective reminding for analysis of memory and learning J Verbal Learn Verbal Behav 12 1973 543 550
12. W.G. Rosen, R.C. Mohs, and K.L. Davis A new rating scale for Alzheimer's disease Am J Psychiatry 141 1984 1356 1364
13. A. Rey L'examen clinique en psychologie (The clinical and psychological evaluation) 1964 Presses Universitaries de France Paris, France
14. 18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial Ann Neurol 68 2010 319 329
15. Alemán-Gómez Y, Melie-García L, Valdés- Hernandez P. IBASPM: toolbox for automatic parcellation of brain structures. Presented at the: 12th Annual Meeting of the Organization for Human Brain Mapping, June 11-15, 2006, Florence, Italy. Available on CD-Rom in NeuroImage, Volume 27, No. 1.
16. R. Duara, D.A. Loewenstein, E. Potter, J. Appel, M.T. Greig, and R. Urs Medial temporal lobe atrophy on MRI scans and the diagnosis of Alzheimer's disease Neurology 71 2008 1986 1992
17. J.M. Hilbe Logistic regression models 2009 Chapman & Hall/CRC Press Boca Raton, FL
18. R. Duara, D.A. Loewenstein, M.T. Greig-Custo, A. Acevedo, E. Potter, and J. Appel Reliability and validity of an algorithm for the diagnosis of normal cognition, MCI and dementia: implications for multi-center research studies Am J Geriatr Psychiatry 18 2010 363 370
19. Q. Shen, D.A. Loewenstein, E. Potter, W. Zhao, J. Appel, and M.T. Greig Volumetric and visual rating of magnetic resonance imaging scans in the diagnosis of amnestic mild cognitive impairment and Alzheimer's disease Alzheimers Dement 7 2011 e101 e108
20. M. Bobinski, M.J. de Leon, J. Wegiel, S. Desanti, A. Convit, and L.A. Saint Louis The histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in Alzheimer's disease Neuroscience 95 2000 721 725
21. E.J. Burton, R. Barber, E.B. Mukaetova-Ladinska, J. Robson, R.H. Perry, and E. Jaros Medial temporal lobe atrophy on MRI differentiates Alzheimer's disease from dementia with Lewy bodies and vascular cognitive impairment: a prospective study with pathological verification of diagnosis Brain 132 2009 195 203
22. E.M. Reiman, A. Uecker, R.J. Caselli, S. Lewis, D. Bandy, and M.J. de Leon Hippocampal volumes in cognitively normal persons at genetic risk for Alzheimer's disease Ann Neurol 44 1998 288 291
23. T. den Heijer, F. van der Lijn, P.J. Koudstaal, A. Hofman, A. van der Lugt, and G.P. Krestin A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline Brain 133 2010 1163 1172
24. D.A. Loewenstein, A. Acevedo, J. Agron, and R. Duara Stability of neurocognitive impairment in different subtypes of mild cognitive impairment Dement Geriatr Cog Disord 23 2006 82 86
25. C. Jack, V.J. Loew, M.L. Senjem, S.D. Weigand, B.J. Kemp, and M.M. Shiung 11-C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment Brain 131 2008 665 680
26. E.C. Mormino, J.T. Kluth, C.M. Madison, G.D. Rabinovici, S.L. Baker, and B. Miller Episodic memory loss is related to hippocampal-mediated β-amyloid deposition in elderly subjects Brain 132 2009 1310 1323
27. K.E. Pike, K.A. Ellis, V.L. Villemagne, N. Good, G. Chételat, and D. Ames Cognition and beta-amyloid in preclinical Alzheimer's disease: data from the AIBL study Neuropsychologia 49 2011 2384 2390
28. W.J. Jagust, L. Zheng, D.J. Harvey, W.J. Mack, H.V. Vinters, and M.W. Weiner Neuropathological basis of magnetic resonance images in aging and dementia Ann Neurol 63 2008 72 80
29. I. Driscoll, Y. Zhou, Y. An, J. Sojkova, C. Davatzikos, and M.A. Kraut Lack of association between 11C-PiB and longitudinal brain atrophy in non-demented older individuals Neurobiol Aging 32 2010 2123 2130
30. G. Chételat, V.L. Villemagne, P. Bourgeat, K.E. Pike, G. Jones, and D. Ames Relationship between atrophy and β-amyloid deposition in Alzheimer disease Ann Neurol 67 2010 317 324
31. S.W. Pimplikar, R.A. Nixon, N.K. Robakis, J. Shen, and L.H. Tsai Amyloid-independent mechanisms in Alzheimer's disease pathogenesis J Neurosci 30 2010 14946 14954