Diagnosis of myalgic encephalomyelitis: Where are we now?

Expert Opinion on Medical Diagnostics

Volumn 7, Issue 3, 2013, Pages 221-225

  Maes, Michael ^a,b,c   Anderson, George ^d   Morris, Gerwyn ^e   Berk, Michael ^b,f,g,h  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b DEAKIN UNIVERSITY   (Australia)

^c PNI Clinics   (Thailand)

^d CRC   (United Kingdom)

^e Mumbles Head ^*  (United Kingdom)

^f UNIVERSITY OF MELBOURNE   (Australia)

^g Flory Institute of Neuroscience and Mental Health   (Australia)

^h UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Case definition; Chronic fatigue; Chronic fatigue syndrome; Diagnosis; Immune; Inflammation; Myalgic encepahlomyelitis

Indexed keywords

BIOLOGICAL MARKER;

ALGORITHM; CHRONIC FATIGUE SYNDROME; CONSENSUS; DIAGNOSIS RELATED GROUP; DISEASE SEVERITY; EVIDENCE BASED PRACTICE; HUMAN; PATTERN RECOGNITION; REVIEW; SYMPTOM; WORLD HEALTH ORGANIZATION; FATIGUE SYNDROME, CHRONIC; PUBLIC HEALTH SERVICE; UNITED STATES;

CENTERS FOR DISEASE CONTROL AND PREVENTION (U.S.); FATIGUE SYNDROME, CHRONIC; HUMANS; UNITED STATES; WORLD HEALTH ORGANIZATION;

EID: 84876872615     PISSN: 17530059     EISSN: 17530067     Source Type: Journal    
DOI: 10.1517/17530059.2013.776039     Document Type: Review

References (16)

1. Maes M, Twisk FN. Chronic fatigue syndrome: Harvey and Wessely's (bio) psychosocial model versus a bio (psychosocial) model based on inflammatory and oxidative and nitrosative stress pathways. BMC Med 2010;8:35
2. Morris G, Maes M. A neuro-immune model of Myalgic Encephalomyelitis/ Chronic fatigue syndrome. Metab Brain Dis 2012. [Epub ahead of print]; PubMed PMID: 22718491
3. Komaroff AL, Cho TA. Role of infection and neurologic dysfunction in chronic fatigue syndrome. Semin Neurol 2011;31(3):325-37
4. Klimas NG, Salvato FR, Morgan R, Fletcher MA. Immunologic abnormalities in chronic fatigue syndrome. J Clin Microbiol 1990;28(6):1403-10
5. Myhill S, Booth NE, McLaren-Howard J. Chronic fatigue syndrome and mitochondrial dysfunction. Int J Clin Exp Med 2009;2(1):1-16
6. Maes M, Mihaylova I, Kubera M, et al. IgM-mediated autoimmune responses directed against anchorage epitopes are greater in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) than in major depression. Metab Brain Dis 2012;27(4):415-23
7. http://sciencewatch.com/dr/erf/2010/ 10octerf/
8. WHO: International Classification of Diseases, Eight Edition (ICD-8), 1969. .. The inclusion of ME (CFS) in the International Classification of Diseases (ICD-8) as a Diseases of the Nervous System was a significant step forward in the recognition of ME or CFS as a neurological disorder.
9. Fukuda K, Straus SE, Hickie I, et al. The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann Intern Med 1994;121(12):953
10. Maes M, Twisk FN, Johnson C. Myalgic Encephalomyelitis (ME), Chronic Fatigue Syndrome (CFS), and Chronic Fatigue (CF) are distinguished accurately: results of supervised learning techniques applied on clinical and inflammatory data. Psychiatry Res 2012;200(2-3):754-60
11. Carruthers BM, van de Sande MI, De Meirleir KL, et al. Myalgic encephalomyelitis: international Consensus Criteria. J Intern Med 2011;270(4):327-38
12. Maes M, Cosyns P, Maes L, et al. Clinical subtypes of unipolar depression: part I. A validation of the vital and nonvital clusters. Psychiatry Res 1990;34(1):29-41
13. Maes M, Schotte C, Maes L, Cosyns P. Clinical subtypes of unipolar depression: part II. Quantitative and qualitative clinical differences between the vital and nonvital depression groups. Psychiatry Res 1990;34(1):43-57
14. Maes M, Maes L, Schotte C, et al. Clinical subtypes of unipolar depression: part III. Quantitative differences in various biological markers between the cluster-analytically generated nonvital and vital depression classes. Psychiatry Res 1990;34(1):59-75
15. Nacul LC, Lacerda EM, Pheby D, et al. Prevalence of myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS) in three regions of England: a repeated cross-sectional study in primary care. BMC Med 2011;9:91
16. Light AR, Bateman L, Jo D, et al. Gene expression alterations at baseline and following moderate exercise in patients with Chronic Fatigue Syndrome and Fibromyalgia Syndrome. J Intern Med 2012;271(1):64-81