Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas

PLoS Genetics

Volumn 9, Issue 4, 2013, Pages

  Basten, Sander G ^a   Davis, Erica E ^b   Gillis, Ad J M ^c   van Rooijen, Ellen ^a   Stoop, Hans ^c   Babala, Nikolina ^a   Logister, Ive ^a   Heath, Zachary G ^b   Jonges, Trudy N ^a   Katsanis, Nicholas ^b   Voest, Emile E ^a   van Eeden, Freek J ^a   Medema, Rene H ^a   Ketting, René F ^a   Schulte Merker, Stefan ^a   Looijenga, Leendert H J ^a   Giles, Rachel H ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMINE; GLYCINE; HISTONE H2AX; LEUCINE RESPONSIVE REGULATORY PROTEIN; LEUCINE RICH REPEAT CONTAINING PROTEIN 50; METHIONINE; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE MUTATION; GENETIC ANALYSIS; GENETIC PREDISPOSITION; GENOTYPE; GERM CELL TUMOR; HETEROZYGOSITY; HETEROZYGOSITY LOSS; HUMAN; IMMUNOHISTOCHEMISTRY; NONHUMAN; NONSENSE MUTATION; PEDIGREE ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SEMINOMA; SINGLE NUCLEOTIDE POLYMORPHISM; SPERMATOGONIUM; TUMOR GROWTH; ZEBRA FISH; ANIMAL; GENETICS; MUTATION; TUMOR SUPPRESSOR GENE;

ANIMALIA; DANIO RERIO; VERTEBRATA;

ANIMALS; GENES, TUMOR SUPPRESSOR; GENOTYPE; HUMANS; MUTATION; SEMINOMA; ZEBRAFISH;

EID: 84876871506     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003384     Document Type: Article

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