Intracardiac thrombus: Diagnosis, complications and management

American Journal of the Medical Sciences

Volumn 345, Issue 5, 2013, Pages 391-395

  Egolum, Ugochukwu O ^a   Stover, Daniel G ^a   Anthony, Ryan ^a   Wasserman, Allison M ^a   Lenihan, Daniel ^a   Damp, Julie B ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Emboli; Embolic; Intracardiac thrombus; Thrombi

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; LACTIC ACID; TROPONIN;

ADULT; ALCOHOL CONSUMPTION; ANTICOAGULATION; ARTERIAL PH; ARTERY OCCLUSION; ARTERY THROMBOSIS; ARTICLE; ARTIFICIAL EMBOLISM; BARE METAL STENT; BLOOD VESSEL OCCLUSION; CARDIOGENIC SHOCK; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CASE REPORT; CHRONIC OBSTRUCTIVE LUNG DISEASE; DIABETES MELLITUS; DYSPNEA; ELECTROCARDIOGRAM; EXTRACORPOREAL OXYGENATION; FAINTNESS; HEART CATHETERIZATION; HEART LEFT VENTRICLE EJECTION FRACTION; HIGH RISK PATIENT; HUMAN; HYPERTENSION; HYPOKINESIA; INOTROPISM; INTRACARDIAC THROMBOSIS; LACTATE BLOOD LEVEL; LEG SWELLING; LUNG ARTERY PRESSURE; MALE; PERIPHERAL VASCULAR DISEASE; PEROPERATIVE CARE; POSTOPERATIVE CARE; PROTEIN BLOOD LEVEL; PULMONARY ARTERY OCCLUSION PRESSURE; ST SEGMENT DEPRESSION; ST SEGMENT ELEVATION; THROMBOSIS PREVENTION; UPPER RESPIRATORY TRACT INFECTION; VENA CAVA FILTER;

EID: 84876836756     PISSN: 00029629     EISSN: 15382990     Source Type: Journal    
DOI: 10.1097/MAJ.0b013e318272b0b0     Document Type: Article

References (35)

1. Waller BF, Rohr TM, McLaughlin T, et al. Intracardiac thrombi: Frequency, location, etiology, and complications: A morphologic review - Part V. Clin Cardiol 1995;18:731-4.
2. Adams PC, Cohen M, Chesebro JH, et al. Thrombosis and embolism from cardiac chambers and infected valves. J Am Coll Cardiol 1986;8(6 Suppl B):76B-87B.
3. Obeid AI, al Mudamgha A, Smulyan H. Diagnosis of right atrial mass lesions by transesophageal and transthoracic echocardiography. Chest 1993;103:1447-51.
4. Weinsaft JW, Kim HW, Shah DJ, et al. Detection of left ventricular thrombus by delayed-enhancement cardiovascular magnetic resonance prevalence and markers in patients with systolic dysfunction. J Am Coll Cardiol 2008;52:148-57.
5. Weinsaft JW, Kim RJ, RossM, et al. Contrast-enhanced anatomic imaging as compared to contrast-enhanced tissue characterization for detection of left ventricular thrombus. JACC Cardiovasc Imaging 2009;2:969-79.
6. Waller BF, Grider L, Rohr TM, et al. Intracardiac thrombi: Frequency, location, etiology, and complications: A morphologic review - Part I. Clin Cardiol 1995;18:477-9.
7. Chesebro JH, Adams PC, Fuster V. Antithrombotic therapy in patients with valvular heart disease and prosthetic heart valves. J Am Coll Cardiol 1986;8(6 Suppl B):41B-56B.
8. Al-Saady NM, Obel OA, Camm AJ. Left atrial appendage: Structure, function, and role in thromboembolism. Heart 1999;82:547-54.
9. Pfeiffer D, Jung W, Fehske W, et al. Complications of pacemakerdefibrillator devices: Diagnosis and management. Am Heart J 1994;127 (4 Pt 2):1073-80.
10. Supple GE, Ren JF, Zado ES, et al. Mobile thrombus on device leads in patients undergoing ablation: Identification, incidence, location, and association with increased pulmonary artery systolic pressure. Circulation 2011;124:772-8.
11. Ahnert AM, Freudenberger RS. What do we know about anticoagulation in patients with heart failure? Curr Opin Cardiol 2008;23:228-32.
12. Dec GW, Fuster V. Idiopathic dilated cardiomyopathy. N Engl J Med 1994;331:1564-75.
13. Vaitkus PT, Barnathan ES. Embolic potential, prevention and management of mural thrombus complicating anterior myocardial infarction: A meta-analysis. J Am Coll Cardiol 1993;22:1004-9.
14. Feng D, Syed IS, Martinez M, et al. Intracardiac thrombosis and anticoagulation therapy in cardiac amyloidosis. Circulation 2009;119: 2490-7.
15. Mogulkoc N, Burgess MI, Bishop PW. Intracardiac thrombus in Behcet's disease: A systematic review. Chest 2000;118:479-87.
16. Carod-Artal FJ, Gascon J. Chagas disease and stroke. Lancet Neurol 2010;9:533-42.
17. Chartier L, Bera J, Delomez M, et al. Free-floating thrombi in the right heart: Diagnosis, management, and prognostic indexes in 38 consecutive patients. Circulation 1999;99:2779-83.
18. Torbicki A, Galie N, Covezzoli A, et al. Right heart thrombi in pulmonary embolism: Results from the International Cooperative Pulmonary Embolism Registry. J Am Coll Cardiol 2003;41:2245-51.
19. Rose PS, Punjabi NM, Pearse DB. Treatment of right heart thromboemboli. Chest 2002;121:806-14.
20. Visser CA, Kan G, David GK, et al. Two dimensional echocardiography in the diagnosis of left ventricular thrombus. A prospective study of 67 patients with anatomic validation. Chest 1983;83:228-32.
21. Waller BF, Howard J, Fess S. Pathology of tricuspid valve stenosis and pure tricuspid regurgitation - Part I. Clin Cardiol 1995;18:97-102.
22. Rockson SG, Albers GW. Comparing the guidelines: Anticoagulation therapy to optimize stroke prevention in patients with atrial fibrillation. J Am Coll Cardiol 2004;43:929-35.
23. Meurin P, Tabet JY, Renaud N, et al. Treatment of left ventricular thrombi with a low molecular weight heparin. Int J Cardiol 2005;98: 319-23.
24. Srichai MB, Junor C, Rodriguez LL, et al. Clinical, imaging, and pathological characteristics of left ventricular thrombus: A comparison of contrast-enhanced magnetic resonance imaging, transthoracic echocardiography, and transesophageal echocardiography with surgical or pathological validation. Am Heart J 2006;152:75-84.
25. Visser CA, Kan G, Meltzer RS, et al. Embolic potential of left ventricular thrombus after myocardial infarction: A two-dimensional echocardiographic study of 119 patients. J Am Coll Cardiol 1985;5:1276-80.
26. Turpie AG, Robinson JG, Doyle DJ, et al. Comparison of high-dose with low-dose subcutaneous heparin to prevent left ventricular mural thrombosis in patients with acute transmural anterior myocardial infarction. N Engl J Med 1989;320:352-7.
27. Kushner FG, Hand M, Smith SC Jr, et al. 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update) a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2009;54:2205-41.
28. Falk RH, Foster E, Coats MH. Ventricular thrombi and thromboembolism in dilated cardiomyopathy: A prospective follow-up study. Am Heart J 1992;123:136-42.
29. Pfeffer MA, Braunwald E, Moye LA, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med 1992;327: 669-77.
30. Massie BM, Collins JF, Ammon SE, et al. Randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: The Warfarin and Antiplatelet Therapy in Chronic Heart Failure (WATCH) trial. Circulation 2009;119:1616-24.
31. Cleland JG, Findlay I, Jafri S, et al. The Warfarin/Aspirin Study in Heart failure (WASH): A randomized trial comparing antithrombotic strategies for patients with heart failure. Am Heart J 2004;148:157-64.
32. Homma S, Thompson JLP, Pullicino PM, et al. Warfarin and aspirin in patients with heart failure and sinus rhythm. N Engl J Med 2012;366: 1859-69.
33. Hunt SA, Abraham WT, Chin MH, et al. ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): Developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: Endorsed by the Heart Rhythm Society. Circulation 2005;112:e154-235.
34. Heik SC, Kupper W, Hamm C, et al. Efficacy of high dose intravenous heparin for treatment of left ventricular thrombi with high embolic risk. J Am Coll Cardiol 1994;24:1305-09.
35. Leacche M, Unic D, Goldhaber SZ, et al. Modern surgical treatment of massive pulmonary embolism: Results in 47 consecutive patients after rapid diagnosis and aggressive surgical approach. J Thorac Cardiovasc Surg 2005;129:1018-23.