Biological and tumor-promoting effects of dioxin-like and non-dioxin-like polychlorinated biphenyls in mouse liver after single or combined treatment

Toxicological Sciences

Volumn 133, Issue 1, 2013, Pages 29-41

  Rignall, Benjamin ^a   Grote, Konstanze ^b   Gavrilov, Alina ^a   Weimer, Marc ^c   Kopp Schneider, Annette ^c   Krause, Eberhard ^d   Appel, Klaus E ^e   Buchmann, Albrecht ^a   Robertson, Larry W ^f   Lehmler, Hans Joachim ^f   Kania Korwel, Izabela ^f   Chahoud, Ibrahim ^b   Schwarz, Michael ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^e FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^f UNIVERSITY OF IOWA   (United States)

Author keywords

Cyp1a1; Cyp2b10.; PCB126; PCB153; Tumor promotion

Indexed keywords

2,2',4,4',5,5' HEXACHLOROBIPHENYL; 3,3',4,4',5 PENTACHLOROBIPHENYL; BIOLOGICAL MARKER; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 1A1; CYTOCHROME P450 2B; CYTOCHROME P450 2B10; DIETHYLNITROSAMINE; DIOXIN; MESSENGER RNA; POLYCHLORINATED BIPHENYL; POLYCHLORINATED BIPHENYL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL COMPOSITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; LIVER CARCINOGENESIS; LIVER LEVEL; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEOMICS; RISK ASSESSMENT; TUMOR GROWTH;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BLOTTING, WESTERN; COCARCINOGENESIS; CYTOCHROME P-450 CYP1A1; DIETHYLNITROSAMINE; DIOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME INDUCTION; IMMUNOHISTOCHEMISTRY; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICE; MICE, INBRED C3H; POLYCHLORINATED BIPHENYLS; STEROID HYDROXYLASES;

MUS;

EID: 84876809253     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft034     Document Type: Article

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