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Volumn 19, Issue 3, 2013, Pages 351-354

The Rodin (Research Of Determinants of INhibitor Development among PUPs with haemophilia) study: The clinical conundrum from the perspective of haemophilia treaters

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIBODY; BLOOD CLOTTING FACTOR 8 ANTIBODY; RECOMBINANT BLOOD CLOTTING FACTOR 8; VON WILLEBRAND FACTOR;

EID: 84876794924     PISSN: 13518216     EISSN: 13652516     Source Type: Journal    
DOI: 10.1111/hae.12149     Document Type: Note
Times cited : (28)

References (12)
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    • (2013) N Engl J Med , vol.368 , pp. 231-239
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  • 3
    • 84876787851 scopus 로고    scopus 로고
    • the PedNet and Rodin Study Group. Factor VIII prophylaxis and inhibitor development in previously untreated patients with severe hemophilia A: the Rodin study. In: The etiology of inhibitor development in children with severe hemophilia A. Thesis. Utrecht University. 2011. Chapter 7, page 167-94. Available at Accessed March 4, 2013.
    • Gouw SC, van den Berg HM, van der Bom JG, the PedNet and Rodin Study Group. Factor VIII prophylaxis and inhibitor development in previously untreated patients with severe hemophilia A: the Rodin study. In: The etiology of inhibitor development in children with severe hemophilia A. Thesis. Utrecht University. 2011. Chapter 7, page 167-94. Available at http://igitur-archive.library.uu.nl/dissertations/2011-1110-200501/gouw.pdf. Accessed March 4, 2013.
    • Gouw, S.C.1    van den Berg, H.M.2    van der Bom, J.G.3
  • 4
    • 0023216759 scopus 로고
    • Statistical problems in the reporting of clinical trials
    • Pocock SJ, Lee RJ. Statistical problems in the reporting of clinical trials. N Engl J Med 1987; 317: 426-32.
    • (1987) N Engl J Med , vol.317 , pp. 426-432
    • Pocock, S.J.1    Lee, R.J.2
  • 5
    • 15344351616 scopus 로고    scopus 로고
    • Full-length sucrose-formulated recombinant factor VIII for treatment of previously untreated or minimally treated young children with severe haemophilia
    • Kreuz W, Gill JC, Rothchild C et al. Full-length sucrose-formulated recombinant factor VIII for treatment of previously untreated or minimally treated young children with severe haemophilia. Thromb Haemost 2005; 93: 457-67.
    • (2005) Thromb Haemost , vol.93 , pp. 457-467
    • Kreuz, W.1    Gill, J.C.2    Rothchild, C.3
  • 6
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    • In vitro characterization of recombinant factor VIII concentrates reveals significant differences in protein content, activity and thrombin activation profile
    • doi: 10.1111/hae.12076 [Epub ahead of print].
    • Pahl S, Pavlova A, Driesen J, Müller J, Pötzsch B, Oldenburg J. In vitro characterization of recombinant factor VIII concentrates reveals significant differences in protein content, activity and thrombin activation profile. Haemophilia 2012. doi: 10.1111/hae.12076 [Epub ahead of print].
    • (2012) Haemophilia
    • Pahl, S.1    Pavlova, A.2    Driesen, J.3    Müller, J.4    Pötzsch, B.5    Oldenburg, J.6
  • 7
    • 80055114308 scopus 로고    scopus 로고
    • Can B-domain deletion alter the immunogenicity of recombinant factor VIII? A meta- analysis of prospective clinical studies
    • Aledort LM, Navickis RJ, Wilkes MM. Can B-domain deletion alter the immunogenicity of recombinant factor VIII? A meta- analysis of prospective clinical studies J Thromb Haemost 2011; 9: 2180-92.
    • (2011) J Thromb Haemost , vol.9 , pp. 2180-2192
    • Aledort, L.M.1    Navickis, R.J.2    Wilkes, M.M.3
  • 8
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    • The central role of the propensity score in observational studies for causal effects
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  • 10
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    • Unraveling the genetics of inhibitors in hemophilia
    • Gouw SC, Fijnvandraat K. Unraveling the genetics of inhibitors in hemophilia. Thromb Hemost 2013; 121: 1250-1.
    • (2013) Thromb Hemost , vol.121 , pp. 1250-1251
    • Gouw, S.C.1    Fijnvandraat, K.2
  • 11
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    • F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis
    • Gouw SC, van den Berg M, Oldenburg J et al. F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis. Blood 2012; 119: 2922-34.
    • (2012) Blood , vol.119 , pp. 2922-2934
    • Gouw, S.C.1    van den Berg, M.2    Oldenburg, J.3
  • 12
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    • European Medicines Agency. Available at Accessed September 3, 2013.
    • European Medicines Agency. Available at http://www.ema.europa.eu/ema/index.jsp?curl=pages/news_and_events/news/2013/03/news_detail_001732.jsp&mid=WC0b01ac058004d5c1. Accessed September 3, 2013.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.