The European General Practice Research Network Presents a Comprehensive Definition of Multimorbidity in Family Medicine and Long Term Care, Following a Systematic Review of Relevant Literature

Journal of the American Medical Directors Association

Volumn 14, Issue 5, 2013, Pages 319-325

  Le Reste, Jean Yves ^a   Nabbe, Patrice ^a   Manceau, Benedicte ^a   Lygidakis, Charilaos ^b   Doerr, Christa ^c   Lingner, Heidrun ^d   Czachowski, Slawomir ^e   Munoz, Miguel ^f   Argyriadou, Stella ^g   Claveria, Ana ^h   Le Floch, Bernard ^a   Barais, Marie ^a   Bower, Peter ⁱ   Van Marwijk, Harm ^j   Van Royen, Paul ^k   Lietard, Claire ^a  

^a UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

^b Associazione Italiana Medici di Famiglia (AIMEF)   (Italy)

^c UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^d HANNOVER MEDICAL SCHOOL   (Germany)

^e NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^f Research Institute University Primary Care IDIAP Jordi Gol   (Spain)

^g The Greek Association of General Practitioners (ELEGEIA)   (Greece)

^h Xerencia de Atención Primaria de Vigo   (Spain)

ⁱ UNIVERSITY OF MANCHESTER   (United Kingdom)

^j VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^k UNIVERSITY OF ANTWERP   (Belgium)

more..

Author keywords

Epidemiology; Family medicine; Multimorbidity; Research

Indexed keywords

CHRONIC DISEASE; COPING BEHAVIOR; FAMILY MEDICINE; FRAIL ELDERLY; HEALTH CARE UTILIZATION; HUMAN; MORBIDITY; QUALITY OF LIFE; REVIEW; RISK FACTOR; SOCIAL NETWORK; SYSTEMATIC REVIEW;

EID: 84876783045     PISSN: 15258610     EISSN: 15389375     Source Type: Journal    
DOI: 10.1016/j.jamda.2013.01.001     Document Type: Review

References (75)

1. Brandlmeier P. Multimorbidity among elderly patients in an urban general practice. ZFA (Stuttgart) 1976, 52:1269-1275.
2. Heuft G. Future research perspectives of a psychoanalytical gerontopsychophysiology-personality and the aging process. Z Gerontol 1990, 23:262-266.
3. Starfield B. Global health, equity, and primary care. J Am Board Fam Med 2007, 20:511-513.
4. Beasley J.W., Starfield B., van Weel C., et al. Global health and primary care research. J Am Board Fam Med 2007, 20:518-526.
5. Boyd C.M., Shadmi E., Conwell L.J., et al. A pilot test of the effect of guided care on the quality of primary care experiences for multimorbid older adults. J Gen Intern Med 2008, 23:536-542.
6. Primary Health Care-Now more than ever 2008, World Health Organization. The World Health Report 2008, The World Health Report, New York, p. 148.
7. the European Definition of General Practice/Family Medicine 2002, European Academy of Teachers in General Practice (Network within Wonca Europe), WONCA.
8. Huber M., Knottnerus J.A., Green L., et al. How should we define health?. BMJ 2011, 343:d4163.
9. Fried L.P., Ferrucci L., Darer J., et al. Untangling the concepts of disability, frailty, and comorbidity: Implications for improved targeting and care. J Gerontol A Biol Sci Med Sci 2004, 59:255-263.
10. Abellan van Kan G., Rolland Y.M., Morley J.E., Vellas B. Frailty: Toward a clinical definition. J Am Med Dir Assoc 2008, 9:71-72.
11. Gobbens R.J.J., van Assen M.A.L.M., Luijkx K.G., et al. Determinants of frailty. J Am Med Dir Assoc 2010, 11:356-364.
12. Hummers-Pradier E., Beyer M., Chevallier P., et al. Series: The research agenda for general practice/family medicine and primary health care in Europe. Part 4. Results: Specific problem solving skills. Eur J Gen Pract 2010, 16:174-181.
13. Le Reste J.Y., Nabbe P., Lygidakis C., et al. A research group from the European General Practice Research Network (EGPRN) explores the concept of multimorbidity for further research into long-term care. J Am Med Dir Assoc 2012, 13.
14. Le Reste JY. The FPDM (Family Practice Depression and Multimorbidity) Study: Project for systematic review of literature to find criteria for multimorbidity definition. Paper presented at: the EGPRN (European General Practitioner Research Network) meeting; May 2011; Nice, France.
15. Liberati A., Altman D.G., Tetzlaff J., et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med 2009, 6:e1000100.
16. Summa J., Hunger A., Platt D. Multimorbidity in old age. Med Welt 1995, 46:232-237.
17. Grimby A., Svanborg A. Morbidity and health-related quality of life among ambulant elderly citizens. Aging (Milan, Italy) 1997, 9:356-364.
18. Linden M., Kurtz G., Baltes M.M., et al. Depression in the very elderly. Nervenarzt 1998, 69:27-37.
19. Schilling S., Pollmeier G., Hardt R. Influencing factors and results of geriatric rehabilitation treatment-Einflussfaktoren Und Ergebnisse Geriatrischer Rehabilitation. Geriatrie Forschung 1998, 8:123-126.
20. Gassmann K., Lang E. The influence of multimorbidity and old age on geriatric rehabilitation. Geriatrie Forschung 1999, 9:54-59.
21. Van den Akker M., Buntinx F., Metsemakers J.F., Knottnerus J.A. Marginal impact of psychosocial factors on multimorbidity: Results of an explorative nested case-control study. Soc Sci Med 2000, 50:1679-1693.
22. Hessel A., Gunzelmann T., Geyer M., Brähler E. Utilization of medical services and medication intake of patients over 60 in Germany-health related, social structure related, socio-demographic and subjective factors. Z Gerontol Geriatr 2000, 33:289-299.
23. Van den Akker M., Buntinx F., Metsemakers J.F., et al. Psychosocial patient characteristics and GP-registered chronic morbidity: A prospective study. J Psychosom Res 2001, 50:95-102.
24. Neeleman J., Ormel J., Bijl R.V. The distribution of psychiatric and somatic III health: associations with personality and socioeconomic status. Psychosom Med 2001, 63:239-247.
25. Angst J., Sellaro R., Ries Merikangas K. Multimorbidity of psychiatric disorders as an indicator of clinical severity. Eur Arch Psychiatry Clin Neurosci 2002, 252:147-154.
26. John R., Kerby D.S., Hennessy C.H. Patterns and impact of comorbidity and multimorbidity among community-resident American Indian elders. Gerontologist 2003, 43:649-660.
27. Fortin M., Lapointe L., Hudon C., Vanasse A. Multimorbidity is common to family practice: Is it commonly researched?. Can Fam Physician 2005, 51:244-245.
28. Noël P.H., Frueh B.C., Larme A.C., Pugh J.A. Collaborative care needs and preferences of primary care patients with multimorbidity. Health Expect 2005, 8:54-63.
29. Fortin M., Hudon C., Dubois M.-F., et al. Comparative assessment of three different indices of multimorbidity for studies on health-related quality of life. Health Qual Life Outcomes 2005, 3:74.
30. Byles J.E., D'Este C., Parkinson L., et al. Single index of multimorbidity did not predict multiple outcomes. J Clin Epidemiol 2005, 58:997-1005.
31. Fortin M., Bravo G., Hudon C., et al. Prevalence of multimorbidity among adults seen in family practice. Ann Fam Med 2005, 3:223-228.
32. Van den Akker M., Vos R., Knottnerus J.A. In an exploratory prospective study on multimorbidity general and disease-related susceptibility could be distinguished. J Clin Epidemiol 2006, 59:934-939.
33. Batstra L., Neeleman J., Elsinga C., Hadders-Algra M. Psychiatric morbidity is related to a chain of prenatal and perinatal adversities. Early Hum Dev 2006, 82:721-729.
34. Castel S., Rush B., Urbanoski K., Toneatto T. Overlap of clusters of psychiatric symptoms among clients of a comprehensive addiction treatment service. Psychol Addict Behav 2006, 20:28-35.
35. Fortin M., Bravo G., Hudon C., et al. Relationship between multimorbidity and health-related quality of life of patients in primary care. Qual Life Res 2006, 15:83-91.
36. Fortin M., Bravo G., Hudon C., et al. Psychological distress and multimorbidity in primary care. Ann Fam Med 2006, 4:417-422.
37. Kadam U.T., Croft P.R. Clinical multimorbidity and physical function in older adults: A record and health status linkage study in general practice. Fam Pract 2007, 24:412-419.
38. Whitson H.E., Cousins S.W., Burchett B.M., et al. The combined effect of visual impairment and cognitive impairment on disability in older people. J Am Geriatr Soc 2007, 55:885-891.
39. Noël P.H., Parchman M.L., Williams J.W., et al. The challenges of multimorbidity from the patient perspective. J Gen Intern Med 2007, 22:419-424.
40. Stålbrand I.S., Svensson T., Elmståhl S., et al. Subjective health and illness, coping and life satisfaction in an 80-year-old Swedish population-implications for mortality. Int J Behav Med 2007, 14:173-180.
41. Min L.C., Wenger N.S., Fung C., et al. Multimorbidity is associated with better quality of care among vulnerable elders. Med Care 2007, 45:480-488.
42. Schram M.T., Frijters D., van de Lisdonk E.H., et al. Setting and registry characteristics affect the prevalence and nature of multimorbidity in the elderly. J Clin Epidemiol 2008, 61:1104-1112.
43. Hudon C., Soubhi H., Fortin M. Relationship between multimorbidity and physical activity: Secondary analysis from the Quebec health survey. BMC Public Health 2008, 8:304.
44. Britt H.C., Harrison C.M., Miller G.C., Knox S.A. Prevalence and patterns of multimorbidity in Australia. Med J Aust 2008, 189:72-77.
45. Glynn L.G., Buckley B., Reddan D., et al. Multimorbidity and risk among patients with established cardiovascular disease: A cohort study. Br J Gen Pract 2008, 58:488-494.
46. Laux G., Kuehlein T., Rosemann T., Szecsenyi J. Co- and multimorbidity patterns in primary care based on episodes of care: Results from the German CONTENT project. BMC Health Serv Res 2008, 8:14.
47. Tooth L., Hockey R., Byles J., Dobson A. Weighted multimorbidity indexes predicted mortality, health service use, and health-related quality of life in older women. J Clin Epidemiol 2008, 61:151-159.
48. Marengoni A., Petroboni B., Casella S., et al. Total lymphocyte count and in-hospital mortality in older persons with multimorbidity. Aging Clin Exp Res 2008, 20:290-296.
49. Nagel G., Peter R., Braig S., et al. The impact of education on risk factors and the occurrence of multimorbidity in the EPIC-Heidelberg cohort. BMC Public Health 2008, 8:384.
50. Kadam U.T., Schellevis F.G., Lewis M., et al. Does age modify the relationship between morbidity severity and physical health in English and Dutch family practice populations?. Qual Life Res 2009, 18:209-220.
51. Marengoni A., von Strauss E., Rizzuto D., et al. The impact of chronic multimorbidity and disability on functional decline and survival in elderly persons. A community-based, longitudinal study. J Intern Med 2009, 265:288-295.
52. Bayliss E.A., Ellis J.L., Steiner J.F. Seniors' self-reported multimorbidity captured biopsychosocial factors not incorporated into two other data-based morbidity measures. J Clin Epidemiol 2009, 62:550-557.
53. Marengoni A., Rizzuto D., Wang H.-X., et al. Patterns of chronic multimorbidity in the elderly population. J Am Geriatr Soc 2009, 57:225-230.
54. Loza E., Jover J.A., Rodriguez L., Carmona L. Multimorbidity: Prevalence, effect on quality of life and daily functioning, and variation of this effect when one condition is a rheumatic disease. Semin Arthritis Rheum 2009, 38:312-319.
55. Hodek J.M., Ruhe A., Greiner W. Multimorbidity and health-related quality of life among elderly persons. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2009, 52:1188-1201.
56. Akner G. Analysis of multimorbidity in individual elderly nursing home residents. Development of a multimorbidity matrix. Arch Gerontol Geriatr 2009, 49:413-419.
57. Holzapfel N., Löwe B., Wild B., et al. Self-care and depression in patients with chronic heart failure. Heart Lung 2009, 38:392-397.
58. Valderas J.M., Starfield B., Sibbald B., et al. Defining comorbidity: Implications for understanding health and health services. Ann Fam Med 2009, 7:357-363.
59. Fortin M., Hudon C., Haggerty J., et al. Prevalence estimates of multimorbidity: A comparative study of 2 sources. BMC Health Serv Res 2010, 10:111.
60. Taylor A.W., Price K., Gill T.K., et al. Multimorbidity-not just an older person's issue. Results from an Australian biomedical study. BMC Public Health 2010, 10:718.
61. Smith S.M., O'Kelly S., O'Dowd T. GPs' and pharmacists' experiences of managing multimorbidity: A "Pandora's box". Br J Gen Pract 2010, 60:285-294.
62. Andrade L.H., Benseñor I.M., Viana M.C., et al. Clustering of psychiatric and somatic illnesses in the general population: Multimorbidity and socioeconomic correlates. Braz J Med Biol Res 2010, 43:483-491.
63. Stecker T., Fortney J., Owen R., et al. Co-occurring medical, psychiatric, and alcohol-related disorders among veterans returning from Iraq and Afghanistan. Psychosomatics 2010, 51:503-507.
64. Hodek J.-M., Ruhe A.-K., Greiner W. Relationship between health-related quality of life and multimorbidity. Gesundheitswesen 2010, 72:455-465.
65. Diederichs C., Berger K., Bartels D.B. The measurement of multiple chronic diseases-a systematic review on existing multimorbidity indices. J Gerontol A Biol Sci Med Sci 2011, 66:301-311.
66. Aarts S., van den Akker M., Tan F.E.S., et al. Influence of multimorbidity on cognition in a normal aging population: A 12-year follow-up in the Maastricht Aging Study. Int J Geriatr Psychiatry 2011, 26:1046-1053.
67. O'Brien R., Wyke S., Guthrie B., et al. An "endless struggle": a qualitative study of general practitioners' and practice nurses' experiences of managing multimorbidity in socio-economically deprived areas of Scotland. Chronic Illn 2011, 7:45-59.
68. Aarts S., van den Akker M., Hajema K.J., et al. Multimorbidity and its relation to subjective memory complaints in a large general population of older adults. Int Psychogeriatr 2011, 23:616-624.
69. Hudon C., Fortin M., Vanasse A. Cumulative Illness Rating Scale was a reliable and valid index in a family practice context. J Clin Epidemiol 2005, 58:603-608.
70. Engel G. The need for a new medical model: A challenge for biomedicine. Science 1977, 196:129-136.
71. Sumsion T. The Delphi technique: An adaptive research tool. Br J Occup Ther 1998, 61:153-156.
72. Hasson F., Keeney S., McKenna H. Research guidelines for the Delphi survey technique. J Adv Nurs 2000, 32:1008-1015.
73. Soler J.-K., Okkes I., Wood M., Lamberts H. The coming of age of ICPC: Celebrating the 21st birthday of the International Classification of Primary Care. Fam Pract 2008, 25:312-317.
74. Steel K., Jónsson P.V., Dupasquier J.N., et al. Systems of care for frail older persons. InterRAI. Trans Am Clin Climatol Assoc 1999, 110:30-35.
75. Salisbury C. Multimorbidity: Redesigning health care for people who use it. Lancet 2012, 6736:12-13.