Evaluation of real-time PCR, galactomannan enzyme-linked immunosorbent assay (ELISA), and a novel lateral-flow device for diagnosis of invasive aspergillosis

Journal of Clinical Microbiology

Volumn 51, Issue 5, 2013, Pages 1510-1516

  White, P Lewis ^a   Parr, Christian ^a,b   Thornton, Christopher ^c   Barnes, Rosemary A ^b  

^a UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF EXETER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GALACTOMANNAN; GLYCOPROTEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY JF5; RNA 28S; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; FUNGUS ANTIGEN; MANNAN;

ADULT; ANALYTICAL PARAMETERS; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DIAGNOSTIC EQUIPMENT; DIAGNOSTIC TEST ACCURACY STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; INTERMETHOD COMPARISON; INVASIVE ASPERGILLOSIS; LATERAL-FLOW DEVICE; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PERFORMANCE; PREDICTIVE VALUE; PRIORITY JOURNAL; PROCESSING TIME; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; ASPERGILLUS; BLOOD; CLASSIFICATION; EVALUATION STUDY; GENETICS; IMMUNOLOGY; INVASIVE PULMONARY ASPERGILLOSIS; MIDDLE AGED;

ANTIBODIES, MONOCLONAL; ANTIGENS, FUNGAL; ASPERGILLUS; BIOLOGICAL MARKERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; INVASIVE PULMONARY ASPERGILLOSIS; MALE; MANNANS; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; RNA, RIBOSOMAL, 28S; SENSITIVITY AND SPECIFICITY;

EID: 84876747359     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.03189-12     Document Type: Article

References (23)

1. De Pauw B, Walsh TJ, Donnelly JP, Stevens DA, Edwards JE, Calandra T, Pappas PG, Maertens J, Lortholary O, Kauffman CA, Denning DW, Patterson TF, Maschmeyer G, Bille J, Dismukes WE, Herbrecht R, Hope WW, Kibbler CC, Kullberg BJ, Marr KA, Muñoz P, Odds FC, Perfect JR, Restrepo A, Ruhnke M, Segal BH, Sobel JD, Sorrell TC, Viscoli C, Wingard JR, Zaoutis T, Bennett JE, European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group, National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. 2008. Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. Clin. Infect. Dis. 46:1813-1821.
2. Karageorgopoulos DE, Vouloumanou EK, Ntziora F, Michalopoulos A, Rafailidis PI, Falagas ME. 2011.-D-Glucan assay for the diagnosis of invasive fungal infections: a meta-analysis. Clin. Infect. Dis. 52:750-770.
3. Leeflang MM, Debets-Ossenkopp YJ, Visser CE, Scholten RJ, Hooft L, Bijlmer HA, Reitsma JB, Bossuyt PM, Vandenbroucke-Grauls CM. 2008. Galactomannan detection for invasive aspergillosis in immunocompromised patients. Cochrane Database Syst. Rev. 8(4):CD007394. doi:10 .1002/14651858.CD007394.
4. Maertens J, Theunissen K, Lagrou K. 2010. Galactomannan testing, p 105-124. In Pasqualotto AC (ed), Aspergillosis: from diagnosis to prevention, 1st ed. Springer Publishers, London, United Kingdom.
5. Mengoli C, Cruciani M, Barnes RA, Loeffler J, Donnelly JP. 2009. Use of PCR for diagnosis of invasive aspergillosis: systematic review and metaanalysis. Lancet Infect. Dis. 9:89-96.
6. Barnes RA, White PL, Bygrave C, Evans N, Healy B, Kell J. 2009. Clinical impact of enhanced diagnosis of invasive fungal disease in high-risk haematology and stem cell transplant patients. J. Clin. Pathol. 62:64-69.
7. White PL, Bretagne S, Klingspor L, Melchers WJ, McCulloch E, Schulz B, Finnstrom N, Mengoli C, Barnes RA, Donnelly JP, Loeffler J, European Aspergillus PCR Initiative. 2010. Aspergillus PCR: one step closer to standardization. J. Clin. Microbiol. 48:1231-1240.
8. White PL, Mengoli C, Bretagne S, Cuenca-Estrella M, Finnstrom N, Klingspor L, Melchers WJ, McCulloch E, Barnes RA, Donnelly JP, Loeffler J, European Aspergillus PCR Initiative (EAPCRI). 2011. Evaluation of Aspergillus PCR protocols for testing serum specimens. J. Clin. Microbiol. 49:3842-3848.
9. Torelli R, Sanguinetti M, Moody A, Pagano L, Caira M, De Carolis E, Fuso L, De Pascale G, Bello G, Antonelli M, Fadda G, Posteraro B. 2011. Diagnosis of invasive aspergillosis by a commercial real-time PCR assay for Aspergillus DNA in bronchoalveolar lavage fluid samples from highrisk patients compared to a galactomannan enzyme immunoassay. J. Clin. Microbiol. 49:4273-4278.
10. White PL, Perry MD, Moody A, Follett SA, Morgan G, Barnes RA. 2011. Evaluation of analytical and preliminary clinical performance of Myconostica MycAssay Aspergillus when testing serum specimens for diagnosis of invasive aspergillosis. J. Clin. Microbiol. 49:2169-2174.
11. Thornton CR. 2008. Development of an immunochromatographic lateral-flow device for rapid serodiagnosis of invasive aspergillosis. Clin. Vaccine Immunol. 15:1095-1105.
12. Wiederhold NP, Thornton CR, Najvar LK, Kirkpatrick WR, Bocanegra R, Patterson TF. 2009. Comparison of lateral flow technology and galactomannan and (1¡3)-beta-D-glucan assays for detection of invasive pulmonary aspergillosis. Clin. Vaccine Immunol. 16:1844-1846.
13. Hoenigl M, Koidl C, Duettmann W, Seeber K, Wagner J, Buzina W, Wölfler A, Raggam RB, Thornton CR, Krause R. 2012. Bronchoalveolar lavage lateral-flow device test for invasive pulmonary aspergillosis diagnosis in haematological malignancy and solid organ transplant patients. J. Infect. 65:588-591.
14. White PL, Linton CJ, Perry MD, Johnson EM, Barnes RA. 2006. The evolution and evaluation of a whole blood polymerase chain reaction assay for the detection of invasive aspergillosis in hematology patients in a routine clinical setting. Clin. Infect. Dis. 42:479-486.
15. Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista M, Mueller R, Nolan T, Pfaffl MW, Shipley GL, Vandesompele J, Wittwer CT. 2009. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin. Chem. 55:611-622.
16. Newcombe RG. 1998. Improved confidence intervals for the difference between binomial proportions based on paired data. Stat. Med. 17:2635-2650.
17. Viera AJ, Garrett JM. 2005. Understanding interobserver agreement: the kappa statistic. Fam. Med. 37:360-363.
18. Faulstich K, Gruler R, Eberhard M, Lentzsch D, Haberstroh K. 2009. Handheld and portable reader devices for lateral flow immunoassays, p 157-183. In Wong RC, Tse HY (ed), Lateral flow immunoassay. Humana Press, New York, NY.
19. Mennink-Kersten MA, Ruegebrink D, Wasei N, Melchers WJ, Verweij PE. 2006. In vitro release by Aspergillus fumigatus of galactofuranose antigens, 1,3-beta-D-glucan, and DNA, surrogate markers used for diagnosis of invasive aspergillosis. J. Clin. Microbiol. 44:1711-1718.
20. Morton CO, Loeffler J, De Luca A, Frost S, Kenny C, Duval S, Romani L, Rogers TR. 2010. Dynamics of extracellular release of Aspergillus fumigatus DNA and galactomannan during growth in blood and serum. J. Med. Microbiol. 59:408-413.
21. Green R, Shibuya K, Ando T. 2009. Histology and radiology, p 373-390. In Latge J-P, Steinbach WJ (ed), Aspergillus fumigatus and aspergillosis. ASM Press, Washington, DC.
22. Caillot D, Couaillier JF, Bernard A, Casasnovas O, Denning DW, Mannone L, Lopez J, Couillault G, Piard F, Vagner O, Guy H. 2001. Increasing volume and changing characteristics of invasive pulmonary aspergillosis on sequential thoracic computed tomography scans in patients with neutropenia. J. Clin. Oncol. 19:253-259.
23. Verweij PE. 2005. Advances in diagnostic testing. Med. Mycol. 43:S121-S124.