메뉴 건너뛰기




Volumn 13, Issue 1, 2013, Pages 35-44

Outcomes of patients with chronic heart failure and iron deficiency treated with intravenous iron: A meta-analysis

Author keywords

Anemia; Chronic heart failure; EPO; Erythropoietin; Heart failure; Intravenous iron; Iron deficiency

Indexed keywords

C REACTIVE PROTEIN; FERRIC CARBOXYMALTOSE; IRON;

EID: 84876743344     PISSN: 1871529X     EISSN: None     Source Type: Journal    
DOI: 10.2174/1871529X11313010004     Document Type: Article
Times cited : (40)

References (35)
  • 1
    • 63849177462 scopus 로고    scopus 로고
    • Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation
    • Hunt, S.A.; Abraham, W.T.; Chin, M.H.; Feldman, A.M.; Francis, G.S.; Ganiats, T.G.; et al. 2009 Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation. J. Am. Coll. Cardiol., 2009, 53(15), e1-e90.
    • (2009) J. Am. Coll. Cardiol , vol.53 , Issue.15
    • Hunt, S.A.1    Abraham, W.T.2    Chin, M.H.3    Feldman, A.M.4    Francis, G.S.5    Ganiats, T.G.6
  • 2
    • 53249090182 scopus 로고    scopus 로고
    • ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: The Task Force for the diagnosis and treatment of acute and chronic heart failure 2008 of the European Society of Cardiology
    • Task Force for Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of European Society of Cardiology, ESC Committee for Practice Guidelines, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Filippatos G, et al, Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM)
    • Task Force for Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of European Society of Cardiology, Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJ, Ponikowski P, Poole-Wilson PA, et al.; ESC Committee for Practice Guidelines, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Filippatos G, et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the diagnosis and treatment of acute and chronic heart failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM). Eur. Heart J., 2008 29(19), 2388-2442.
    • (2008) Eur. Heart J , vol.29 , Issue.19 , pp. 2388-2442
    • Dickstein, K.1    Cohen-Solal, A.2    Filippatos, G.3    McMurray, J.J.4    Ponikowski, P.5    Poole-Wilson, P.A.6
  • 3
    • 0037005813 scopus 로고    scopus 로고
    • Confirmation of a heart failure epidemic: Findings from the Resource Utilization Among Congestive Heart Failure (REACH) study
    • McCullough, P.A.; Philbin, E.F.; Spertus, J.A.; Kaatz, S.; Sandberg, K.R.; Weaver, W.D. Confirmation of a heart failure epidemic: findings from the Resource Utilization Among Congestive Heart Failure (REACH) study. J. Am. Coll Cardiol., 2002, 39(1), 60-69.
    • (2002) J. Am. Coll Cardiol , vol.39 , Issue.1 , pp. 60-69
    • McCullough, P.A.1    Philbin, E.F.2    Spertus, J.A.3    Kaatz, S.4    Sandberg, K.R.5    Weaver, W.D.6
  • 4
    • 0037024202 scopus 로고    scopus 로고
    • Anemia is associated with worse symptoms, greater impairment in functional capacity and a significant increase in mortality in patients with advanced heart failure
    • Horwich, T.B.; Fonarow, G.C.; Hamilton, M.A.; MacLellan, W.R.; Borenstein, J. Anemia is associated with worse symptoms, greater impairment in functional capacity and a significant increase in mortality in patients with advanced heart failure. J. Am. Coll Cardiol., 2002, 39(11), 1780-1786.
    • (2002) J. Am. Coll Cardiol , vol.39 , Issue.11 , pp. 1780-1786
    • Horwich, T.B.1    Fonarow, G.C.2    Hamilton, M.A.3    Maclellan, W.R.4    Borenstein, J.5
  • 5
    • 0037976873 scopus 로고    scopus 로고
    • Anemia predicts mortality in severe heart failure: The prospective randomized amlodipine survival evaluation (PRAISE)
    • Mozaffarian, D.; Nye, R.; Levy, W.C. Anemia predicts mortality in severe heart failure: the prospective randomized amlodipine survival evaluation (PRAISE). J. Am. Coll Cardiol., 2003, 41(11), 1933-1939.
    • (2003) J. Am. Coll Cardiol , vol.41 , Issue.11 , pp. 1933-1939
    • Mozaffarian, D.1    Nye, R.2    Levy, W.C.3
  • 10
    • 1642393242 scopus 로고    scopus 로고
    • Tissue iron deficiency without anemia impairs adaptation in endurance capacity after aerobic training in previously untrained women
    • Brownlie, T.; Utermohlen, V.; Hinton, P.S.; Haas, J.D. Tissue iron deficiency without anemia impairs adaptation in endurance capacity after aerobic training in previously untrained women. Am. J. Clin. Nutr., 2004, 79(3), 437-443.
    • (2004) Am. J. Clin. Nutr , vol.79 , Issue.3 , pp. 437-443
    • Brownlie, T.1    Utermohlen, V.2    Hinton, P.S.3    Haas, J.D.4
  • 11
    • 0242691880 scopus 로고
    • Muscle mitochondrial bioenergetics, oxygen supply, and work capacity during dietary iron deficiency and repletion
    • Davies, K.J.; Maguire, J.J.; Brooks, G.A.; Dallman, P.R.; Packer, L. Muscle mitochondrial bioenergetics, oxygen supply, and work capacity during dietary iron deficiency and repletion. Am. J. Physiol., 1982, 242(6), E418-E427.
    • (1982) Am. J. Physiol , vol.242 , Issue.6
    • Davies, K.J.1    Maguire, J.J.2    Brooks, G.A.3    Dallman, P.R.4    Packer, L.5
  • 12
    • 0034128813 scopus 로고    scopus 로고
    • The use of subcutaneous erythropoietin and intravenous iron for the treatment of the anemia of severe, resistant congestive heart failure improves cardiac and renal function and functional cardiac class, and markedly reduces hospitalizations
    • Silverberg, D.S.; Wexler, D.; Blum, M.; Keren, G.; Sheps, D.; Leibovitch, E.; et al. The use of subcutaneous erythropoietin and intravenous iron for the treatment of the anemia of severe, resistant congestive heart failure improves cardiac and renal function and functional cardiac class, and markedly reduces hospitalizations. J. Am. Coll. Cardiol., 2000, 35(7), 1737-1744.
    • (2000) J. Am. Coll. Cardiol , vol.35 , Issue.7 , pp. 1737-1744
    • Silverberg, D.S.1    Wexler, D.2    Blum, M.3    Keren, G.4    Sheps, D.5    Leibovitch, E.6
  • 13
    • 70350567772 scopus 로고    scopus 로고
    • A pilot evaluation of the long-term effect of combined therapy with intravenous iron sucrose and erythropoietin in elderly patients with advanced chronic heart failure and cardio-renal anemia syndrome: Influence of neurohormonal activiation and clinical outcomes
    • Comin-Colet, J.; Ruiz, S.; Cladellas, M.; Rizzo, M.; Torres, A.; Bruguera, J. A pilot evaluation of the long-term effect of combined therapy with intravenous iron sucrose and erythropoietin in elderly patients with advanced chronic heart failure and cardio-renal anemia syndrome: influence of neurohormonal activiation and clinical outcomes. J. Card. Fail., 2009, 15(9), 727-735.
    • (2009) J. Card. Fail , vol.15 , Issue.9 , pp. 727-735
    • Comin-Colet, J.1    Ruiz, S.2    Cladellas, M.3    Rizzo, M.4    Torres, A.5    Bruguera, J.6
  • 15
    • 50049102529 scopus 로고    scopus 로고
    • Intravenous iron without erythropoietin for the treatment of iron deficiency anemia in patients with moderate to severe congestive heart failure and chronic kidney insufficiency
    • Usmanov, R.I.; Zueva, E.B.; Silverberg, D.S.; Shaked, M. Intravenous iron without erythropoietin for the treatment of iron deficiency anemia in patients with moderate to severe congestive heart failure and chronic kidney insufficiency. J. Nephrol., 2008, 21, 236-242.
    • (2008) J. Nephrol , vol.21 , pp. 236-242
    • Usmanov, R.I.1    Zueva, E.B.2    Silverberg, D.S.3    Shaked, M.4
  • 17
    • 35248870765 scopus 로고    scopus 로고
    • Intravenous iron reduced NT-pro-brain natriuretic peptide in anemic patients with chronic heart failure and renal insufficiency
    • Toblli, J.E.; Lombrana, A.; Duarte, P.; Di Gennaro F. Intravenous iron reduced NT-pro-brain natriuretic peptide in anemic patients with chronic heart failure and renal insufficiency. J. Am. Coll Cardiol., 2007, 50(17),1657-1665.
    • (2007) J. Am. Coll Cardiol , vol.50 , Issue.17 , pp. 1657-1665
    • Toblli, J.E.1    Lombrana, A.2    Duarte, P.3    Di Gennaro, F.4
  • 18
    • 0035370037 scopus 로고    scopus 로고
    • The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: A randomized, controlled study
    • Silverberg, D.S.; Wexler, D.; Sheps, D.; Blum, M.; Keren, G.; Baruch, R.; Schwartz, D.; Yachnin, T.; Steinbruch, S.; Shapira, I.; Laniado, S.; Iaina, A. The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: a randomized, controlled study. J. Am. Coll. Cardiol., 2001, 37(7), 1775-1780.
    • (2001) J. Am. Coll. Cardiol , vol.37 , Issue.7 , pp. 1775-1780
    • Silverberg, D.S.1    Wexler, D.2    Sheps, D.3    Blum, M.4    Keren, G.5    Baruch, R.6    Schwartz, D.7    Yachnin, T.8    Steinbruch, S.9    Shapira, I.10    Laniado, S.11    Iaina, A.12
  • 20
    • 84876698458 scopus 로고    scopus 로고
    • Pubmed Home. Accessed on-line on June 5, 2010 at
    • Pubmed Home. Accessed on-line on June 5, 2010 at: http://www.pubmed.gov.
  • 21
    • 84876732414 scopus 로고    scopus 로고
    • Home - Clinicaltrials.gov. Accessed on line on June 5, 2010 at
    • Home - Clinicaltrials.gov. Accessed on line on June 5, 2010 at: http://www.clinicaltrials.gov.
  • 22
    • 84876710245 scopus 로고    scopus 로고
    • The Cochrane Library. Accessed on-line on June 5, 2010 at
    • The Cochrane Library. Accessed on-line on June 5, 2010 at: http://www.mrw.interscience.wiley.com/cochrane/cochrane_clcentral_articles_fs.html.
  • 23
    • 0026699989 scopus 로고
    • Assessment of patient outcome with the Minnesota Living with Heart Failure questionnaire: Reliability and validity during a randomized, double blind, placebo-controlled trial of pimobendan. Pimobendan Multicenter Research Group
    • Rector, T.S.; Cohn, J.N. Assessment of patient outcome with the Minnesota Living with Heart Failure questionnaire: reliability and validity during a randomized, double blind, placebo-controlled trial of pimobendan. Pimobendan Multicenter Research Group. Am. Heart J., 1992, 124,1017-1025.
    • (1992) Am. Heart J , vol.124 , pp. 1017-1025
    • Rector, T.S.1    Cohn, J.N.2
  • 24
    • 0027195028 scopus 로고
    • Validity of the Minnesota Living with Heart Failure questionnaire as a measure of therapeutic response to enalapril or placebo
    • Rector, T.S.; Kubo, S.H.; Cohn, J.N. Validity of the Minnesota Living with Heart Failure questionnaire as a measure of therapeutic response to enalapril or placebo. Am. J. Cardiol., 1993, 71,1106-1107.
    • (1993) Am. J. Cardiol , vol.71 , pp. 1106-1107
    • Rector, T.S.1    Kubo, S.H.2    Cohn, J.N.3
  • 25
    • 0034039691 scopus 로고    scopus 로고
    • Development and evaluation of the Kansas City Cardiomyopathy questionnaire: A new health status measure for heart failure
    • Green, C.P.; Porter, C.B.; Bresnahan XX, Spertus J.A. Development and evaluation of the Kansas City Cardiomyopathy questionnaire: a new health status measure for heart failure. J. Am. Coll. Cardiol., 2000, 35, 1245-1255.
    • (2000) J. Am. Coll. Cardiol , vol.35 , pp. 1245-1255
    • Green, C.P.1    Porter, C.B.2    Bresnahan, X.X.3    Spertus, J.A.4
  • 26
    • 84890613528 scopus 로고    scopus 로고
    • Chapter 16: Special topics in statistics
    • In: Higgins JPT, Green S (editors), updated September 2008, The Cochrane Collaboration, Available from
    • Higgins, J.P.T.; Deeks, J.J.; Altman, D.G.; (editors). Chapter 16: Special topics in statistics. In: Higgins JPT, Green S (editors), Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 (updated September 2008). The Cochrane Collaboration, 2008. Available from www.cochrane-handbook.org.
    • (2008) Cochrane Handbook For Systematic Reviews of Interventions Version 5.0.1
    • Higgins, J.P.T.1    Deeks, J.J.2    Altman, D.G.3
  • 28
    • 84890783342 scopus 로고    scopus 로고
    • Chapter 9: Analysing data and undertaking meta-analyses
    • In: Higgins JPT, Green S (editors), updated September 2008, The Cochrane Collaboration, Available from
    • Deeks JJ, Higgins JPT, Altman DG (editors). Chapter 9: Analysing data and undertaking meta-analyses. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 (updated September 2008). The Cochrane Collaboration, 2008. Available from www.cochrane-handbook.org.
    • (2008) Cochrane Handbook For Systematic Reviews of Interventions Version 5.0.1
    • Deeks, J.J.1    Higgins, J.P.T.2    Altman, D.G.3
  • 29
    • 0034812030 scopus 로고    scopus 로고
    • Reduced kidney function and anemia as risk factors for mortality in patients with left ventricular dysfunction
    • Al-Ahmad, A.; Rand, W.M.; Manjunath, G.; Konstam, M.A.; Salem, D.N.; Levey, A.S.; et al. Reduced kidney function and anemia as risk factors for mortality in patients with left ventricular dysfunction. J. Am. Coll. Cardiol., 2001, 38, 955-962.
    • (2001) J. Am. Coll. Cardiol , vol.38 , pp. 955-962
    • Al-Ahmad, A.1    Rand, W.M.2    Manjunath, G.3    Konstam, M.A.4    Salem, D.N.5    Levey, A.S.6
  • 30
    • 33947204175 scopus 로고    scopus 로고
    • Emerging role of anemia in heart failure
    • Mitchell, J.E. Emerging role of anemia in heart failure. Am. J. Cardiol., 2007, 99(6B), 15D-20D.
    • (2007) Am. J. Cardiol , vol.99 , Issue.6 B
    • Mitchell, J.E.1
  • 32
    • 0033162263 scopus 로고    scopus 로고
    • Advances in the anemia of chronic disease
    • Means, R.T.; Advances in the anemia of chronic disease. Int. J. Hematol., 1999, 70(1), 7-12.
    • (1999) Int. J. Hematol , vol.70 , Issue.1 , pp. 7-12
    • Means, R.T.1
  • 33
    • 0029862870 scopus 로고    scopus 로고
    • Factors which alter the relationship between ventilation and carbon dioxide production during exercise in normal subjects
    • Clark, A.L.; Volterrani, M.; Piepoli, M.; Coats, A.J. Factors which alter the relationship between ventilation and carbon dioxide production during exercise in normal subjects. Eur. J. Appl. Physiol. Occup. Physiol., 1996, 73(1-2), 144-148.
    • (1996) Eur. J. Appl. Physiol. Occup. Physiol , vol.73 , Issue.1-2 , pp. 144-148
    • Clark, A.L.1    Volterrani, M.2    Piepoli, M.3    Coats, A.J.4
  • 34
    • 0023785393 scopus 로고
    • Skeletal muscles metabolism during exercise under ischemic condtions in congestive heart failure. Evidence for abnormalities unrelated to blood flow
    • Massie, B.M.; Conway, M.; Rajagopalan, B.; Yonge, R.; Frostick, S.; Ledingham, J.; Sleight, P.; Radda, G. Skeletal muscles metabolism during exercise under ischemic condtions in congestive heart failure. Evidence for abnormalities unrelated to blood flow. Circulation, 1988, 78, 320-326.
    • (1988) Circulation , vol.78 , pp. 320-326
    • Massie, B.M.1    Conway, M.2    Rajagopalan, B.3    Yonge, R.4    Frostick, S.5    Ledingham, J.6    Sleight, P.7    Radda, G.8
  • 35
    • 77249139676 scopus 로고    scopus 로고
    • A meta-analysis of erythropoiesis-stimulating agents in anaemic patients with chronic heart failure
    • Jin, B.; Luo, X.; Lin, H.; Li, J.; Shi, H. A meta-analysis of erythropoiesis-stimulating agents in anaemic patients with chronic heart failure. Eur. J. Heart Fail., 2010, 12(3), 249-253.
    • (2010) Eur. J. Heart Fail , vol.12 , Issue.3 , pp. 249-253
    • Jin, B.1    Luo, X.2    Lin, H.3    Li, J.4    Shi, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.